A local anesthetic, ropivacaine, suppresses activated microglia via a nerve growth factor-dependent mechanism and astrocytes via a nerve growth factor-independent mechanism in neuropathic pain

Molecular Pain

Volumn 7, Issue , 2011, Pages

  Toda, Shigeru ^a   Sakai, Atsushi ^a   Ikeda, Yumiko ^a   Sakamoto, Atsuhiro ^a   Suzuki, Hidenori ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CELL MARKER; GLIAL FIBRILLARY ACIDIC PROTEIN; HYBRID PROTEIN; IMMUNOGLOBULIN G; NERVE GROWTH FACTOR; PROTEIN TYROSINE KINASE A; ROPIVACAINE; AMIDE; LOCAL ANESTHETIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL ACTIVATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; HYPERALGESIA; IMMUNOREACTIVITY; MALE; MICROGLIA; NERVE CELL INHIBITION; NERVE CELL LESION; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SCIATIC NERVE; UPREGULATION; ANIMAL; CHRONIC DISEASE; EPIDURAL ANESTHESIA; METABOLISM; NEURALGIA; PATHOLOGY; SPRAGUE DAWLEY RAT; TEMPERATURE;

AMIDES; ANESTHESIA, EPIDURAL; ANESTHETICS, LOCAL; ANIMALS; ASTROCYTES; CHRONIC DISEASE; HYPERALGESIA; MALE; MICROGLIA; NERVE GROWTH FACTORS; NEURALGIA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKA; TEMPERATURE;

EID: 78650926554     PISSN: None     EISSN: 17448069     Source Type: Journal    
DOI: 10.1186/1744-8069-7-2     Document Type: Article

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