Glucosamine inhibits epidermal growth factor-induced proliferation and cell-cycle progression in retinal pigment epithelial cells

Molecular Vision

Volumn 16, Issue , 2010, Pages 2559-2571

  Liang, Chang Min ^a,b   Tai, Ming Cheng ^b   Chang, Yun Hsiang ^b   Chen, Yi Hao ^b   Chen, Ching Long ^b   Chien, Ming Wei ^a   Chen, Jiann Torng ^a,b  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE; CYCLIN E; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GLUCOSAMINE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEAT SHOCK PROTEIN 90; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; STAT3 PROTEIN;

APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL LINE; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INHIBITION KINETICS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

BETA CATENIN; CELL CYCLE; CELL DEATH; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLINS; ENDOPLASMIC RETICULUM; EPIDERMAL GROWTH FACTOR; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLUCOSAMINE; GLYCOSYLATION; HUMANS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; RETINAL PIGMENT EPITHELIUM; STAT3 TRANSCRIPTION FACTOR; STRESS, PHYSIOLOGICAL; TRANSCRIPTIONAL ACTIVATION;

EID: 78650797075     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Pastor JC. Proliferative Vitreoretinopathy: An Overview. Surv Ophthalmol 1998; 43:3-18. [PMID: 9716190]
2. He S, Chen Y, Khankan R, Barron E, Burton R, Zhu D, Ryan SJ, Oliver N, Hinton DR. Connective tissue growth factor as a mediator of intraocular fibrosis. Invest Ophthalmol Vis Sci 2008; 49:4078-88. [PMID: 18450591]
3. Yan F, Hui YN, Li YJ, Guo CM, Meng H. Epidermal growth factor receptor in cultured human retinal pigment epithelial cells. Ophthalmologica 2007; 221:244-50. [PMID: 17579290]
4. Defoe DM, Grindstaff RD. Epidermal growth factor stimulation of RPE cell survival: contribution of phosphatidylinositol 3- kinase and mitogen-activated protein kinase pathways. Exp Eye Res 2004; 79:51-9. [PMID: 15183100]
5. Leschey KH, Hackett SF, Singer JH, Campochiaro PA. Growth factor responsiveness of human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 1990; 31:839-46. [PMID: 2186011]
6. Spraul CW, Kaven C, Lang GK, Lang GE. Effect of growth factors on bovine retinal pigment epithelial cell migration and proliferation. Ophthalmic Res 2004; 36:166-71. [PMID: 15103208]
7. Steindl-Kuscher K, Krugluger W, Boulton ME, Haas P, Schrattbauer K, Feichtinger H, Adlassnig W, Binder S. Activation of the beta-catenin signaling pathway and its impact on RPE cell cycle. Invest Ophthalmol Vis Sci 2009; 50:4471-6. [PMID: 19369241]
8. Sugino IK, Wang H, Zarbin MA. Age-related macular degeneration and retinal pigment epithelium wound healing. Mol Neurobiol 2003; 28:177-94. [PMID: 14576455]
9. Khaliq A, Jarvis-Evans J, McLeod D, Boulton M. Oxygen modulates the response of the retinal pigment epithelium to basic fibroblast growth factor and epidermal growth factor by receptor regulation. Invest Ophthalmol Vis Sci 1996; 37:436-43. [PMID: 8603849]
10. Baudouin C, Fredj-Reygrobellet D, Brignole F, Nègre F, Lapalus P, Gastaud P. Growth factors in vitreous and subretinal fluid cells from patients with proliferative vitreoretinopathy. Ophthalmic Res 1993; 25:52-9. [PMID: 8446368]
11. Heidenkummer HP, Kampik A. Immunohistochemical localization of epidermal growth factor receptor in a human epiretinal membrane. Graefes Arch Clin Exp Ophthalmol 1991; 229:492-6. [PMID: 1718825]
12. Chen Z, Chen CZ, Gong WR, Li JP, Xing YQ. Integrin-alpha5 mediates epidermal growth factor-induced retinal pigment epithelial cell proliferation and migration. Pathobiology 2010; 77:88-95. [PMID: 20332668]
13. Chang YH, Horng CT, Chen YH, Chen PL, Chen CL, Liang CM, Chien MW, Chen JT. Inhibitory Effects of Glucosamine on Endotoxin-Induced Uveitis in Lewis Rats. Invest Ophthalmol Vis Sci 2008; 49:5441-9. [PMID: 18719082]
14. Chen JT, Chen PL, Chang YH, Chien MW, Chen YH, Lu DW. Glucosamine sulfate inhibits leukocyte adhesion in response to cytokine stimulation of retinal pigment epithelial cells in vitro. Exp Eye Res 2006; 83:1052-62. [PMID: 16822504]
15. Chesnokov V, Sun C, Itakura K. Glucosamine suppresses proliferation of human prostate carcinoma DUI 45 cells through inhibition of STAT3 signaling. Cancer Cell Int 2009; 9:25. [PMID: 19744341]
16. Pan YT, Elbein A. The formation of lipid-linked oligosaccharides in Madin-Darby canine kidney cells. Changes in oligosaccharide profiles induced by glucosamine. J Biol Chem 1982; 257:2795-801. [PMID: 7061450]
17. Carpenter G, Cohen S. Epidermal growth factor. J Biol Chem 1990; 265:7709-12. [PMID: 2186024]
18. Gamou S, Shimizu N. Glycosylation of the epidermal growth factor receptor and its relationship to membrane transport and ligand binding. J Biochem 1988; 104:388-96. [PMID: 3149275]
19. Saika S, Yamanaka O, Nishikawa-Ishida I, Kitano A, Flanders KC, Okada Y, Ohnishi Y, Nakajima Y, Ikeda K. Effect of Smad7 gene overexpression on transforming growth factor beta-induced retinal pigment fibrosis in a proliferative vitreoretinopathy mouse model. Arch Ophthalmol 2007; 125:647-54. [PMID: 17502504]
20. Oda K, Matsuoka Y, Funahashi A, Kitano H. A comprehensive pathway map of epidermal growth factor receptor signaling. Mol Syst Biol 2005; 1:2005.0010.
21. Konishi A, Berk BC. Epidermal Growth Factor Receptor Transactivation Is Regulated by Glucose in Vascular Smooth Muscle Cells. J Biol Chem 2003; 278:35049-56. [PMID: 12829718]
22. Boerner JL, Biscardi JS, Silva CM, Parsons SJ. Transactivating agonists of the EGF receptor require Tyr 845 phosphorylation for induction of DNA synthesis. Mol Carcinog 2005; 44:262-73. [PMID: 16167350]
23. Takahashi M, Tsuda T, Ikeda Y, Honke K, Taniguchi N. Role of N-glycans in growth factor signaling. Glycoconj J 2004; 20:207-12. [PMID: 15090734]
24. Partridge EA, Le Roy C, Di Guglielmo GM, Pawling J, Cheung P, Granovsky M, Nabi IR, Wrana JL, Dennis JW. Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis. Science 2004; 306:120-4. [PMID: 15459394]
25. Bekesi JG, Winzler RJ. Inhibitory effects of D-glucosamine on the growth of Walker 256 carcinosarcoma and on protein, RNA, and DNA synthesis. Cancer Res 1970; 30:2905-12. [PMID: 5494575]
26. Friedman SJ, Skehan P. Membrane-active drugs potentiate the killing of tumor cells by D-glucosamine. Proc Natl Acad Sci USA 1980; 77:1172-6. [PMID: 6928667]
27. Masson E, Wiernsperger N, Lagarde M, El Bawab S. Involvement of gangliosides in glucosamine-induced proliferation decrease of retinal pericytes. Glycobiology 2005; 15:585-91. [PMID: 15625180]
28. Luo Y, Zhuo Y, Fukuhara M, Rizzolo LF. Effects of culture conditions on heterogeneity and the apical junctional complex of the ARPE-19 cell line. Invest Ophthalmol Vis Sci 2006; 47:3644-55. [PMID: 16877439]
29. Tian J, Ishibashi K, Honda S, Boylan SA, Hjelmeland LM, Handa JT. The expression of native and cultured human retinal pigment epithelial cells grown in different culture conditions. Br J Ophthalmol 2005; 89:1510-1517. [PMID: 16234463]
30. Sharma RK, Orr WE, Schmitt AD, Johnson DA. A functional profile of gene expression in ARPE-19 cells. BMC Ophthalmol 2005; 5:25. [PMID: 16262907]
31. Strunnikova NV, Maminishkis A, Barb JJ, Wang F, Zhi C, Sergeev Y, Chen W, Edwards AO, Stambolian D, Abecasis G, Swaroop A, Munson PJ, Miller SS. Transcriptome analysis and molecular signature of human retinal pigment epithelium. Hum Mol Genet 2010; 19:2468-86. [PMID: 20360305]
32. Cai H, Del Priore LV. Gene expression profile of cultured adult compared to immortalized human RPE. Mol Vis 2006; 12:1-14. [PMID: 16446697]