Integrin-α5 mediates epidermal growth factor-induced retinal pigment epithelial cell proliferation and migration

Pathobiology

Volumn 77, Issue 2, 2010, Pages 88-95

  Chen, Zhen ^a   Chen, Chang Zheng ^a   Gong, Wen Rong ^a   Li, Jun Ping ^b,c   Xing, Yi Qiao ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Epidermal growth factor; Integrin 5; Migration; Proliferation; Retinal pigment epithelial cells

Indexed keywords

ALPHA5 INTEGRIN; EPIDERMAL GROWTH FACTOR; MESSENGER RNA;

ADULT; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CELL SURFACE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; MALE; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VITREORETINOPATHY; WESTERN BLOTTING; CELL LINE; CELL MEMBRANE; CELL MOTION; CELL SURVIVAL; DRUG EFFECT; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY;

ADULT; CELL LINE; CELL MEMBRANE; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; EPIDERMAL GROWTH FACTOR; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; HUMANS; INTEGRIN ALPHA5; MALE; MIDDLE AGED; RETINAL PIGMENT EPITHELIUM; VITREORETINOPATHY, PROLIFERATIVE;

EID: 77950148880     PISSN: 10152008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000278290     Document Type: Article

References (35)

1. Charteris DG: Proliferative vitreoretinopathy: pathobiology, surgical management, and adjunctive treatment. Br J Ophthalmol 1995; 79: 953-960.
2. Hoffmann S, He S, Jin M, Ehren M, Wiedemann P, Ryan SJ, Hinton DR: A selective cyclic integrin antagonist blocks the integrin receptors- v-3 and-v- 5 and inhibits retinal pigment epithelium cell attachment, migration and invasion. BMC Ophthalmol 2005; 5: 16.
3. Campochiaro PA, Hackett SF: Corneal endothelial cell matrix promotes expression of differentiated features of retinal pigmented epithelial cells: implication of laminin and basic fibroblast growth factor as active components. Exp Eye Res 1993; 57: 539-547.
4. Miceli MV, Newsome DA: Effects of extracellular matrix and Bruch's membrane on retinal outer segment phagocytosis by cultured human retinal pigment epithelium. Curr Eye Res 1996; 15: 17-26.
5. Priglinger SG, Alge CS, Neubauer AS, Kristin N, Hirneiss C, Eibl K, Kampik A, Welge- Lussen U: TGF-- 2 -induced cell surface tissue transglutaminase increases adhesion and migration of RPE cells on fibronectin through the gelatin-binding domain. Invest Ophthalmol Vis Sci 2004; 45: 955-963.
6. Ioachim E, Stefaniotou M, Gorezis S, Tsanou E, Psilas K, Agnantis NJ: Immunohistochemical study of extracellular matrix components in epiretinal membranes of vitreoproliferative retinopathy and proliferative diabetic retinopathy. Eur J Ophthalmol 2005; 15: 384-391.
7. Springer TA, Wang JH: The three-dimensional structure of integrins and their ligands, and conformational regulation of cell adhesion. Adv Protein Chem 2004; 68: 29-63.
8. Hynes RO: Integrins: bidirectional, allosteric signaling machines. Cell 2002; 110: 673-687.
9. Ramsay AG, Marshall JF, Hart IR: Integrin trafficking and its role in cancer metastasis. Cancer Metastasis Rev 2007; 26: 567-578.
10. Luo BH, Springer TA: Integrin structures and conformational signaling. Curr Opin Cell Biol 2006; 18: 579-586.
11. Somanath PR, Ciocea A, Byzova TV: Integrin and growth factor receptor alliance in angiogenesis. Cell Biochem Biophys 2009; 53: 53-64.
12. Elner SG, Elner VM: The integrin superfamily and the eye. Invest Ophthalmol Vis Sci 1996; 37: 696-701.
13. Aota S, Yamada KM: Fibronectin and cell adhesion: specificity of integrin-ligand interaction. Adv Enzymol Relat Areas Mol Biol 1995; 70: 1-21.
14. Yin Z, Gabriele E, Leprini A, Perris R, Colombatti A: Differential cation regulation of the- 5- 1 -integrin-mediated adhesion of leukemic cells to the central cell-binding domain of fibronectin. Cell Growth Differ 1997; 8: 1339-1347.
15. Nista A, Leonetti C, Bernardini G, Mattioni M, Santoni A: Functional role of- 4- 1 - and- 5- 1 -integrin fibronectin receptors expressed on Adriamycin-resistant MCF-7 human mammary carcinoma cells. Int J Cancer 1997; 72: 133-141.
16. Chon JH, Netzel R, Rock BM, Chaikof EL:- 4- 1 and- 5- 1 control cell migration on fibronectin by differentially regulating cell speed and motile cell phenotype. Ann Biomed Eng 1998; 26: 1091-1101.
17. Hakkinen L, Heino J, Koivisto L, Larjava H: Altered interaction of human granulationtissue fibroblasts with fibronectin is regulated by-5- 1 -integrin. Biochim Biophys Acta 1994; 1224: 33-42.
18. Jin M, He S, Worpel V, Ryan SJ, Hinton DR: Promotion of adhesion and migration of RPE cells to provisional extracellular matrices by TNF-- . Invest Ophthalmol Vis Sci 2000; 41: 4324-4332.
19. Davey G, Buzzai M, Assoian RK: Reduced expression of- 5- 1 -integrin prevents spreading- dependent cell proliferation. J Cell Sc 1999; 112(pt 24):4663-4672.
20. Campochiaro PA: Pathogenic mechanisms in proliferative vitreoretinopathy. Arch Ophthalmol 1997; 115: 237-241.
21. Jin S, Wang Y, Jiang G: Measurements of serum and subretinal fluid before and after surgery of retinal detachment (in Chinese). Zhonghua Yan Ke Za Zhi 1997; 33: 36-38.
22. Hecquet C, Lefèvre G, Valtink M, Engelmann K, Mascarelli F: Activation and role of MAP kinase-dependent pathways in retinal pigment epithelial cells: ERK and RPE cell proliferation. Invest Ophthalmol Vis Sci 2002; 43: 3091-3098.
23. Brem RB, Robbins SG, Wilson DJ, O'Rourke LM, Mixon RN, Robertson JE, Planck SR, Rosenbaum JT: Immunolocalization of integrins in the human retina. Invest Ophthalmol Vis Sci 1994; 35: 3466-3474.
24. Rizzolo LJ, Zhou S, Li ZQ: The neural retina maintains integrins in the apical membrane of the RPE early in development. Invest Ophthalmol Vis Sci 1994; 35: 2567-2576.
25. Proulx S, Guérin SL, Salesse C: Effect of quiescence on integrin--5- 1 expression in human retinal pigment epithelium. Mol Vis 2003; 9: 473-481.
26. Robbins SG, Brem RB, Wilson DJ, O'Rourke LM, Robertson JE, Westra I, Planck SR, Rosenbaum JT: Immunolocalization of integrins in proliferative retinal membranes. Invest Ophthalmol Vis Sci 1994; 35: 3475-3485.
27. Immonen I, Tervo K, Virtanen I, Laatikainen L, Tervo T: Immunohistochemical demonstration of cellular fibronectin and tenascin in human epiretinal membranes. Acta Ophthalmol (Copenh) 1991; 69: 466-471.
28. Goldschild M, Baudouin C: Role of integrins in ocular physiology and diseases (in French). J Fr ophtalmol 1997; 20: 311-325.
29. Hollborn M, Iandiev I, Seifert M, Schnurrbusch UE, Wolf S, Wiedemann P, Bringmann A, Kohen L: Expression of HB-EGF by retinal pigment epithelial cells in vitreoretinal proliferative disease. Curr Eye Res 2006; 31: 863-874.
30. Carpenter G, Cohen S: Epidermal growth factor. J Biol Chem 1990; 265: 7709-7712.
31. Fujii K, Dousaka-Nakajima N, Imamura S: Epidermal growth factor enhancement of HSC-1 human cutaneous squamous carcinoma cell adhesion and migration on type I collagen involves selective up-regulation of-2- 1 -integrin expression. Exp Cell Res 1995; 216: 261-272.
32. Chen JD, Lapiere JC, Sauder DN, Peavey C, Woodley DT: Interleukin-1- stimulates keratinocyte migration through an epidermal growth factor/transforming growth factor-- -independent pathway. J Invest Dermatol 1995; 104: 729-733.
33. Nagineni CN, Kutty V, Detrick B, Hooks JJ: Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-- . J Cell Physiol 2005; 203: 35-43.
34. Eichler W, Reiche A, Yafai Y, Lange J, Wiedemann P: Growth-related effects of oxidantinduced stress on cultured RPE and choroidal endothelial cells. Exp Eye Res 2008; 87: 342-348.
35. Sastry SK, Horwitz AF: Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling. Curr Opin Cell Biol 1993; 5: 819-831.