-
1
-
-
0024342417
-
Functional analysis of the ligand binding site of EGF-receptor utilizing chimeric chicken/human receptor molecules
-
Lax I, Bellot F, Howk R, Ullrich A, Givol D, Schlessinger J. Functional analysis of the ligand binding site of EGF-receptor utilizing chimeric chicken/human receptor molecules. EMBO J 1989;8:421-427.
-
(1989)
EMBO J
, vol.8
, pp. 421-427
-
-
Lax, I.1
Bellot, F.2
Howk, R.3
Ullrich, A.4
Givol, D.5
Schlessinger, J.6
-
2
-
-
0024841734
-
Epidermal growth factor binding induces a conformational change in the external domain of its receptor
-
Greenfield C, Miles I, Waterfield MD, et al. Epidermal growth factor binding induces a conformational change in the external domain of its receptor. EMBO J 1989;8:4115-4123.
-
(1989)
EMBO J
, vol.8
, pp. 4115-4123
-
-
Greenfield, C.1
Miles, I.2
Waterfield, M.D.3
-
3
-
-
0037429737
-
Epidermal growth factor receptor: Mechanisms of activation and signalling
-
Jorissen RN, Walker F, Pouliot N, Garrett TP, Ward CW, Burgess AW. Epidermal growth factor receptor: Mechanisms of activation and signalling. Exp Cell Res 2003;284:31-53.
-
(2003)
Exp Cell Res
, vol.284
, pp. 31-53
-
-
Jorissen, R.N.1
Walker, F.2
Pouliot, N.3
Garrett, T.P.4
Ward, C.W.5
Burgess, A.W.6
-
4
-
-
0024538540
-
Ligand-independent tyrosine phosphorylation of EGF receptor and the erbB-2/neu proto-oncogene product is induced by hyperosmotic shock
-
King CR, Borrello I, Porter L, Comoglio P, Schlessinger J. Ligand-independent tyrosine phosphorylation of EGF receptor and the erbB-2/neu proto-oncogene product is induced by hyperosmotic shock. Oncogene 1989;4:13-18.
-
(1989)
Oncogene
, vol.4
, pp. 13-18
-
-
King, C.R.1
Borrello, I.2
Porter, L.3
Comoglio, P.4
Schlessinger, J.5
-
5
-
-
0029790979
-
Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants, or alkylating agents
-
Knebel A, Rahmsdorf HJ, Ullrich A, Herrlich P. Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants, or alkylating agents. EMBO J 1996;15:5314-5325.
-
(1996)
EMBO J
, vol.15
, pp. 5314-5325
-
-
Knebel, A.1
Rahmsdorf, H.J.2
Ullrich, A.3
Herrlich, P.4
-
6
-
-
0030044360
-
Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
-
Daub H, Weiss FU, Wallasch C, Ullrich A. Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 1996;379:557-560.
-
(1996)
Nature
, vol.379
, pp. 557-560
-
-
Daub, H.1
Weiss, F.U.2
Wallasch, C.3
Ullrich, A.4
-
7
-
-
0033598131
-
Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways
-
Carpenter G. Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways. J Cell Biol 1999;146:697-702.
-
(1999)
J Cell Biol
, vol.146
, pp. 697-702
-
-
Carpenter, G.1
-
8
-
-
0033854267
-
EGF receptor activation by G-protein coupled receptors
-
Harris RC. EGF receptor activation by G-protein coupled receptors. Kidney Int 2000;58:898-899.
-
(2000)
Kidney Int
, vol.58
, pp. 898-899
-
-
Harris, R.C.1
-
9
-
-
0034468086
-
Tyrosine kinase signalling in breast cancer. Epidermal growth factor receptor: Convergence point for signal integration and diversification
-
Prenzel N, Zwick E, Leserer M, Ullrich A. Tyrosine kinase signalling in breast cancer. Epidermal growth factor receptor: Convergence point for signal integration and diversification. Breast Cancer Res 2000;2:184-190.
-
(2000)
Breast Cancer Res
, vol.2
, pp. 184-190
-
-
Prenzel, N.1
Zwick, E.2
Leserer, M.3
Ullrich, A.4
-
10
-
-
0037025389
-
Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation
-
Wu W, Graves LM, Gill GN, Parsons SJ, Samet JM. Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation. J Biol Chem 2002;277:24252-24257.
-
(2002)
J Biol Chem
, vol.277
, pp. 24252-24257
-
-
Wu, W.1
Graves, L.M.2
Gill, G.N.3
Parsons, S.J.4
Samet, J.M.5
-
11
-
-
0030614911
-
Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation
-
Luttrell LM, Della Rocca GJ, van Biesen T, Luttrell DK, Lef kowitz RJ. Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation. J Biol Chem 1997;272:4637-4644.
-
(1997)
J Biol Chem
, vol.272
, pp. 4637-4644
-
-
Luttrell, L.M.1
Della Rocca, G.J.2
Van Biesen, T.3
Luttrell, D.K.4
Lef Kowitz, R.J.5
-
12
-
-
7144227948
-
Growth hormone-induced tyrosine phosphorylation of EGF receptor as an essential element leading to MAP kinase activation and gene expression
-
Yamauchi T, Ueki K, Tobe K, et al. Growth hormone-induced tyrosine phosphorylation of EGF receptor as an essential element leading to MAP kinase activation and gene expression. Endocr J 1998;45:527-531.
-
(1998)
Endocr J
, vol.45
, pp. 527-531
-
-
Yamauchi, T.1
Ueki, K.2
Tobe, K.3
-
13
-
-
0029121267
-
Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: Implications for the etiology of multiple human cancers
-
Maa MC, Leu TH, McCarley DJ, Schatzman RC, Parsons SJ. Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: Implications for the etiology of multiple human cancers. Proc Natl Acad Sci USA 1995;92:6981-6985.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 6981-6985
-
-
Maa, M.C.1
Leu, T.H.2
McCarley, D.J.3
Schatzman, R.C.4
Parsons, S.J.5
-
14
-
-
0033583220
-
C-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function
-
Biscardi JS, Maa MC, Tice DA, Cox ME, Leu TH, Parsons SJ. c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function. J Biol Chem 1999;274:8335-8343.
-
(1999)
J Biol Chem
, vol.274
, pp. 8335-8343
-
-
Biscardi, J.S.1
Maa, M.C.2
Tice, D.A.3
Cox, M.E.4
Leu, T.H.5
Parsons, S.J.6
-
15
-
-
0033573921
-
Mechanism of biological synergy between cellular Src and epidermal growth factor receptor
-
Tice DA, Biscardi JS, Nickles AL, Parsons SJ. Mechanism of biological synergy between cellular Src and epidermal growth factor receptor. Proc Natl Acad Sci USA 1999;96:1415-1420.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1415-1420
-
-
Tice, D.A.1
Biscardi, J.S.2
Nickles, A.L.3
Parsons, S.J.4
-
16
-
-
0024418535
-
Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis
-
Fantl WJ, Escobedo JA, Williams LT. Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis. Mol Cell Biol 1989;9:4473-4478.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 4473-4478
-
-
Fantl, W.J.1
Escobedo, J.A.2
Williams, L.T.3
-
18
-
-
0024478058
-
Pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src
-
Wilson LK, Luttrell DK, Parsons JT, Parsons SJ. pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src. Mol Cell Biol 1989;9:1536-1544.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1536-1544
-
-
Wilson, L.K.1
Luttrell, D.K.2
Parsons, J.T.3
Parsons, S.J.4
-
19
-
-
0031979414
-
Characterization of human epidermal growth factor receptor and c-Src interactions in human breast tumor cells
-
Biscardi JS, Belsches AP, Parsons SJ. Characterization of human epidermal growth factor receptor and c-Src interactions in human breast tumor cells. Mol Carcinog 1998;21:261-272.
-
(1998)
Mol Carcinog
, vol.21
, pp. 261-272
-
-
Biscardi, J.S.1
Belsches, A.P.2
Parsons, S.J.3
-
20
-
-
0024604427
-
Gene amplification and overexpression of EGF receptor in squamous cell carcinomas of the head and neck
-
Ishitoya J, Toriyama M, Oguchi N, et al. Gene amplification and overexpression of EGF receptor in squamous cell carcinomas of the head and neck. Br J Cancer 1989;59:559-562.
-
(1989)
Br J Cancer
, vol.59
, pp. 559-562
-
-
Ishitoya, J.1
Toriyama, M.2
Oguchi, N.3
-
21
-
-
0032933797
-
C-Src, receptor tyrosine kinases, and human cancer
-
Biscardi JS, Tice DA, Parsons SJ. c-Src, receptor tyrosine kinases, and human cancer. Adv Cancer Res 1999;76:61-119.
-
(1999)
Adv Cancer Res
, vol.76
, pp. 61-119
-
-
Biscardi, J.S.1
Tice, D.A.2
Parsons, S.J.3
-
22
-
-
0032054511
-
Overexpression of c-Src in areas of hyperproliferation in head and neck cancer, premalignant lesions and benign mucosal disorders
-
van Oijen MG, Rijksen G, ten Broek FW, Slootweg PJ. Overexpression of c-Src in areas of hyperproliferation in head and neck cancer, premalignant lesions and benign mucosal disorders. J Oral Pathol Med 1998;27:147-152.
-
(1998)
J Oral Pathol Med
, vol.27
, pp. 147-152
-
-
Van Oijen, M.G.1
Rijksen, G.2
Ten Broek, F.W.3
Slootweg, P.J.4
-
23
-
-
0020645860
-
Expression of pp60c-src protein kinase in adult and fetal human tissue: High activities in some sarcomas and mammary carcinomas
-
Jacobs C, Rubsamen H. Expression of pp60c-src protein kinase in adult and fetal human tissue: High activities in some sarcomas and mammary carcinomas. Cancer Res 1983;43:1696-1702.
-
(1983)
Cancer Res
, vol.43
, pp. 1696-1702
-
-
Jacobs, C.1
Rubsamen, H.2
-
24
-
-
0026674221
-
Characterization of protein tyrosine kinases from human breast cancer: Involvement of the c-src oncogene product
-
Ottenhoff-Kalff AE, Rijksen G, van Beurden EA, Hennipman A, Michels AA, Staal GE. Characterization of protein tyrosine kinases from human breast cancer: Involvement of the c-src oncogene product. Cancer Res 1992;52:4773-4778.
-
(1992)
Cancer Res
, vol.52
, pp. 4773-4778
-
-
Ottenhoff-Kalff, A.E.1
Rijksen, G.2
Van Beurden, E.A.3
Hennipman, A.4
Michels, A.A.5
Staal, G.E.6
-
25
-
-
0031979414
-
Characterization of human epidermal growth factor receptor and c-Src interactions in human breast tumor cells
-
Biscardi JS, Belsches AP, Parsons SJ. Characterization of human epidermal growth factor receptor and c-Src interactions in human breast tumor cells. Mol Carcinog 1998;21:261-272.
-
(1998)
Mol Carcinog
, vol.21
, pp. 261-272
-
-
Biscardi, J.S.1
Belsches, A.P.2
Parsons, S.J.3
-
26
-
-
0026641543
-
Endothelin rapidly stimulates mitogen-activated protein kinase activity in rat mesangial cells
-
Wang Y, Simonson MS, Pouyssegur J, Dunn MJ. Endothelin rapidly stimulates mitogen-activated protein kinase activity in rat mesangial cells. Biochem J 1992;287:589-594.
-
(1992)
Biochem J
, vol.287
, pp. 589-594
-
-
Wang, Y.1
Simonson, M.S.2
Pouyssegur, J.3
Dunn, M.J.4
-
27
-
-
0029620504
-
JAK2, Ras, and Raf are required for activation of extracellular signal-regulated kinase/mitogen-activated protein kinase by growth hormone
-
Winston LA, Hunter T. JAK2, Ras, and Raf are required for activation of extracellular signal-regulated kinase/mitogen-activated protein kinase by growth hormone. J Biol Chem 1995;270:30837-30840.
-
(1995)
J Biol Chem
, vol.270
, pp. 30837-30840
-
-
Winston, L.A.1
Hunter, T.2
-
28
-
-
0030903882
-
C-terminal mutation of G protein beta subunit affects differentially extracellular signal-regulated kinase and c-Jun N-terminal kinase pathways in human embryonal kidney 293 cells
-
Yamauchi J, Kaziro Y, Itoh H. C-terminal mutation of G protein beta subunit affects differentially extracellular signal-regulated kinase and c-Jun N-terminal kinase pathways in human embryonal kidney 293 cells. J Biol Chem 1997;272:7602-7607.
-
(1997)
J Biol Chem
, vol.272
, pp. 7602-7607
-
-
Yamauchi, J.1
Kaziro, Y.2
Itoh, H.3
-
29
-
-
0027223986
-
Lysophosphatidic acid induces tyrosine phosphorylation and activation of MAP-kinase and focal adhesion kinase in cultured Swiss 3T3 cells
-
Kumagai N, Morii N, Fujisawa K, Yoshimasa T, Nakao K, Narumiya S. Lysophosphatidic acid induces tyrosine phosphorylation and activation of MAP-kinase and focal adhesion kinase in cultured Swiss 3T3 cells. FEBS Lett 1993;329:273-276.
-
(1993)
FEBS Lett
, vol.329
, pp. 273-276
-
-
Kumagai, N.1
Morii, N.2
Fujisawa, K.3
Yoshimasa, T.4
Nakao, K.5
Narumiya, S.6
-
30
-
-
0029879203
-
Characterization and cloning of STAT5 from IM-9 cells and its activation by growth hormone
-
Silva CM, Lu H, Day RN. Characterization and cloning of STAT5 from IM-9 cells and its activation by growth hormone. Mol Endocrinol 1996;10:508-518.
-
(1996)
Mol Endocrinol
, vol.10
, pp. 508-518
-
-
Silva, C.M.1
Lu, H.2
Day, R.N.3
-
31
-
-
0029115640
-
Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue
-
Liu X, Robinson GW, Gouilleux F, Groner B, Hennighausen L. Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue. Proc Natl Acad Sci USA 1995;92:8831-8835.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8831-8835
-
-
Liu, X.1
Robinson, G.W.2
Gouilleux, F.3
Groner, B.4
Hennighausen, L.5
-
32
-
-
0033546315
-
ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases
-
Olayioye MA, Beuvink I, Horsch K, Daly JM, Hynes NE. ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases. J Biol Chem 1999;274:17209-17218.
-
(1999)
J Biol Chem
, vol.274
, pp. 17209-17218
-
-
Olayioye, M.A.1
Beuvink, I.2
Horsch, K.3
Daly, J.M.4
Hynes, N.E.5
-
33
-
-
0033599039
-
EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
-
Prenzel N, Zwick E, Daub H, et al. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 1999;402:884-888.
-
(1999)
Nature
, vol.402
, pp. 884-888
-
-
Prenzel, N.1
Zwick, E.2
Daub, H.3
-
34
-
-
0037157854
-
The metalloprotease Kuzbanian (ADAM 10) mediates the transactivation of EGF receptor by G protein-coupled receptors.PG-221-6
-
Yan Y, Shirakabe K, Werb Z. The metalloprotease Kuzbanian (ADAM 10) mediates the transactivation of EGF receptor by G protein-coupled receptors.PG-221-6. J Cell Biol 2002;158:221-226.
-
(2002)
J Cell Biol
, vol.158
, pp. 221-226
-
-
Yan, Y.1
Shirakabe, K.2
Werb, Z.3
-
35
-
-
0034737483
-
The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor
-
Maudsley S, Pierce KL, Zamah AM, et al. The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor. J Biol Chem 2000;275:9572-9580.
-
(2000)
J Biol Chem
, vol.275
, pp. 9572-9580
-
-
Maudsley, S.1
Pierce, K.L.2
Zamah, A.M.3
-
36
-
-
0037162024
-
Trans-regulation of epidermal growth factor receptor by lysophosphatidic acid and G protein-coupled receptors
-
Wu J, Cunnick JM. Trans-regulation of epidermal growth factor receptor by lysophosphatidic acid and G protein-coupled receptors. Biochim Biophys Acta 2002;1582:100-106.
-
(2002)
Biochim Biophys Acta
, vol.1582
, pp. 100-106
-
-
Wu, J.1
Cunnick, J.M.2
-
37
-
-
0030656447
-
Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone
-
Yamauchi T, Ueki K, Tobe K, et al. Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone. Nature 1997;390:91-96.
-
(1997)
Nature
, vol.390
, pp. 91-96
-
-
Yamauchi, T.1
Ueki, K.2
Tobe, K.3
-
38
-
-
0037160137
-
Identification of a JAK2-independent pathway regulating growth hormone (GH)-stimulated p44/42 mitogen-activated protein kinase activity. GH activation of Ral and phospholipase D is Src-dependent
-
Zhu T, Ling L, Lobie PE. Identification of a JAK2-independent pathway regulating growth hormone (GH)-stimulated p44/42 mitogen-activated protein kinase activity. GH activation of Ral and phospholipase D is Src-dependent. J Biol Chem 2002;277:45592-45603.
-
(2002)
J Biol Chem
, vol.277
, pp. 45592-45603
-
-
Zhu, T.1
Ling, L.2
Lobie, P.E.3
-
39
-
-
0037449766
-
STAT5b, a mediator of synergism between c-Src and the epidermal growth factor receptor
-
Kloth MT, Laughlin KK, Biscardi JS, Boerner JL, Parsons SJ, Silva CM. STAT5b, a mediator of synergism between c-Src and the epidermal growth factor receptor. J Biol Chem 2003;278:1671-1679.
-
(2003)
J Biol Chem
, vol.278
, pp. 1671-1679
-
-
Kloth, M.T.1
Laughlin, K.K.2
Biscardi, J.S.3
Boerner, J.L.4
Parsons, S.J.5
Silva, C.M.6
-
40
-
-
0034748380
-
Crosstalk between ERs and signal transducer and activator of transcription 5 is E2 dependent and involves two functionally separate mechanisms
-
Faulds MH, Pettersson K, Gustafsson JA, Haldosen LA. Crosstalk between ERs and signal transducer and activator of transcription 5 is E2 dependent and involves two functionally separate mechanisms. Mol Endocrinol 2001;15:1929-1940.
-
(2001)
Mol Endocrinol
, vol.15
, pp. 1929-1940
-
-
Faulds, M.H.1
Pettersson, K.2
Gustafsson, J.A.3
Haldosen, L.A.4
-
41
-
-
0033613938
-
Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes
-
Luttrell LM, Ferguson SS, Daaka Y, et al. Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science 1999;283:655-661.
-
(1999)
Science
, vol.283
, pp. 655-661
-
-
Luttrell, L.M.1
Ferguson, S.S.2
Daaka, Y.3
-
42
-
-
0034268796
-
Src tyrosine kinase is a novel direct effector of G proteins
-
Ma YC, Huang J, Ali S, Lowry W, Huang XY. Src tyrosine kinase is a novel direct effector of G proteins. Cell 2000;102:635-646.
-
(2000)
Cell
, vol.102
, pp. 635-646
-
-
Ma, Y.C.1
Huang, J.2
Ali, S.3
Lowry, W.4
Huang, X.Y.5
|