High-mobility group box 1 promotes early acute allograft rejection by enhancing IL-6-dependent Th17 alloreactive response

Laboratory Investigation

Volumn 91, Issue 1, 2011, Pages 43-53

  Duan, Lihua ^a   Wang, Cong Yi ^a,b   Chen, Jie ^a   Gong, Quan ^a   Zhu, Ping ^a   Zheng, Fang ^a   Tan, Zheng ^a   Gong, Feili ^a   Fang, Min ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

allograft rejection; HMGB1; Th17; transplantation

Indexed keywords

GAMMA INTERFERON; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 17; INTERLEUKIN 6; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; RECOMBINANT PROTEIN;

ACUTE GRAFT REJECTION; ALLOIMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BAGG ALBINO MOUSE; CARDIAC GRAFT REJECTION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; EFFECTOR CELL; FEMALE; GRAFT RECIPIENT; GRAFT SURVIVAL; HEART TRANSPLANTATION; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; IMMUNOSTIMULATION; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL; TH1 CELL; TH17 CELL;

ACUTE DISEASE; ANIMALS; ANTIBODIES, NEUTRALIZING; CELLS, CULTURED; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; HMGB1 PROTEIN; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKIN-6; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES; TH1 CELLS; TH17 CELLS; TRANSPLANTATION, HOMOLOGOUS;

EID: 78650774420     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2010.141     Document Type: Article

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