Transfer of tolerance to collagen type v suppresses T-helper-cell-17 lymphocyte-mediated acute lung transplant rejection

Transplantation

Volumn 88, Issue 12, 2009, Pages 1341-1348

  Braun, Ruedi K ^a   Molitor Dart, Melanie ^b   Wigfield, Christopher ^a   Xiang, Zhuzai ^b   Fain, Sean B ^b   Jankowska Gan, Ewa ^b   Seroogy, Christine M ^b   Burlingham, William J ^b   Wilkes, David S ^c   Brand, David D ^d   Torrealba, Jose ^b   Love, Robert B ^a  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^b University of Wisconsin Health   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Adoptive transfer; Animal model; Autoimmunity; IL 17; Lung transplantation

Indexed keywords

COLLAGEN TYPE 5; INTERLEUKIN 17; TUMOR NECROSIS FACTOR ALPHA;

ACUTE GRAFT REJECTION; ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHIOLITIS; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; EFFECTOR CELL; HISTOCHEMISTRY; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; LUNG GRAFT REJECTION; LUNG TRANSPLANTATION; MEDIASTINUM LYMPH NODE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGULATORY T LYMPHOCYTE; SPLEEN CELL; T CELL DEPLETION; TH17 CELL; VASCULITIS; ACUTE DISEASE; ALLOTRANSPLANTATION; ANIMAL; BIOSYNTHESIS; CELLULAR IMMUNITY; COMPARATIVE STUDY; DISEASE MODEL; FISCHER 344 RAT; GRAFT REJECTION; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; T LYMPHOCYTE SUBPOPULATION; WISTAR KYOTO RAT;

ACUTE DISEASE; ANIMALS; COLLAGEN TYPE V; DISEASE MODELS, ANIMAL; GRAFT REJECTION; IMMUNITY, CELLULAR; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-17; LUNG TRANSPLANTATION; POSITRON-EMISSION TOMOGRAPHY; RATS; RATS, INBRED F344; RATS, INBRED WKY; T-LYMPHOCYTE SUBSETS; TRANSPLANTATION, HOMOLOGOUS;

EID: 74049089202     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e3181bcde7b     Document Type: Article

References (54)

1. Yoshida S, Haque A, Mizobuchi T, et al. Anti-type V collagen lymphocytes that express IL-17 and IL-23 induce rejection pathology in fresh and well-healed lung transplants. Am J Transplant 2006; 6: 724.
2. Burlingham WJ, Love RB, Jankowska-Gan E, et al. IL-17-dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants. J Clin Invest 2007; 117: 3498.
3. Yasufuku K, Heidler KM, Woods KA, et al. Prevention of bronchiolitis obliterans in rat lung allografts by type V collagen-induced oral tolerance. Transplantation 2002; 73: 500.
4. Linsenmayer TF, Gibney E, Igoe F, et al. Type V collagen: Molecular structure and fibrillar organization of the chicken alpha 1(V) NH2-terminal domain, a putative regulator of corneal fibrillogenesis. J Cell Biol 1993; 121: 1181.
5. Schwarze U, Atkinson M, Hoffman GG, et al. Null alleles of the COL5A1 gene of type V collagen are a cause of the classical forms of Ehlers-Danlos syndrome (types I and II). Am J Hum Genet 2000; 66: 1757.
6. Chalasani G, Li Q, Konieczny BT, et al. The allograft defines the type of rejection (acute versus chronic) in the face of an established effector immune response. J Immunol 2004; 172: 7813.
7. Chanut-DelalandeH, Bonod-BidaudC,CogneS,etal. Development of a functional skin matrix requires deposition of collagen V heterotrim-ers. Mol Cell Biol, 2004:24;6049
8. Haque MA, Mizobuchi T, Yasufuku K, et al. Evidence for immune responses to a self-antigen in lung transplantation: Role of type V collagen-specific T cells in the pathogenesis of lung allograft rejection. J Immunol 2002; 169: 1542.
9. Park H, Li Z, Yang XO, et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 2005; 6: 1133.
10. Bettelli E, Oukka M, Kuchroo VK. T(H)-17 cells in the circle of immunity and autoimmunity. Nat Immunol 2007; 8: 345.
11. Acosta-Rodriguez EV, NapolitaniG,LanzavecchiaA,etal. Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol 2007; 8: 942.
12. Bettelli E, Korn T, Oukka M, et al. Induction and effector functions of T(H)17 cells. Nature 2008; 453: 1051.
13. Kelly MN, Kolls JK, Happel K, et al. Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection. Infect Immun 2005; 73: 617.
14. Ye P, Garvey PB, Zhang P, et al. Interleukin-17 and lung host defense against Klebsiella pneumoniae infection. Am J Respir Cell Mol Biol 2001; 25: 335.
15. Huang W, Na L, Fidel PL, et al. Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. JInfect Dis 2004; 190: 624.
16. Aggarwal S, Gurney AL. IL-17: Prototype member of an emerging cytokine family. J Leukoc Biol 2002; 71:1.
17. Zhang GX, Xu H, Kishi M, et al. The role of IL-12 in the induction of intravenous tolerance in experimental autoimmune encephalomyelitis. J Immunol 2002; 168:2501.
18. Li H, Ciric B, Yang J, et al. Intravenous tolerance modulates macrophage classical activation and antigen presentation in experimental autoimmune encephalomyelitis. J Neuroimmunol 2009; 208: 54.
19. Faria AM, Weiner HL. Oral tolerance. Immunol Rev 2005; 206: 232.
20. Mizobuchi T, Yasufuku K, Zheng Y, et al. Differential expression of Smad7 transcripts identifies the CD4( + )CD45RC(high) regulatory T cells that mediate type V collagen-induced tolerance to lung allografts. J Immunol 2003; 171: 1140.
21. +CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen. J Immunol 2001; 167: 188.
22. + regulatory T cells and suppresses delayed-type hypersensitivity reactions. Scand J Immunol 2006; 64: 251.
23. Seidel-Guyenot W, Perschon S, Dechant N, et al. Low zone tolerance induced by systemic application of allergens inhibits Tc1-mediated skin inflammation. J Allergy Clin Immunol 2006; 117: 1170.
24. + T regulatory cells. Invest Ophthalmol Vis Sci 2006; 47: 1047.
25. Kamphorst AO, da Silva MF, da Silva AC, et al. Genetic selection for resistance or susceptibility to oral tolerance to ovalbumin affects general mechanisms of tolerance induction in mice. Ann N Y Acad Sci 2004; 1029: 350.
26. Mizuta T, Nakahara K, Shirakura R, et al. Total nonmicrosuture technique for rat lung transplantation. J Thorac Cardiovasc Surg 1991; 102:159.
27. Mizuta T, Kawaguchi A, Nakahara K, et al. Simplified rat lung transplantation using a cuff technique. J Thorac Cardiovasc Surg 1989; 97:578.
28. Mizobuchi T, Sekine Y, Yasufuku K, et al. Comparison of surgical procedures for vascular and airway anastomoses that utilize a modified non-suture external cuff technique for experimental lung transplantation in rats. J Heart Lung Transplant 2004; 23: 889.
29. Yasufuku K, Heidler KM, O'Donnell PW, et al. Oral tolerance induction by type V collagen downregulates lung allograft rejection. Am J Respir Cell Mol Biol 2001; 25: 26.
30. Kearney ER, Pape KA, Loh DY, et al. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1994; 1: 327.
31. Green LA, Gambhir SS, Srinivasan A, et al. Noninvasive methods for quantitating blood time-activity curves from mouse PET images obtained with fluorine-18-fluorodeoxyglucose. J Nucl Med 1998; 39: 729.
32. Yousem SA, Berry GJ, Cagle PT, et al. Revision of the 1990 working formulation for the classification of pulmonary allograft rejection: Lung Rejection Study Group. J Heart Lung Transplant 1996; 15: 1.
33. Lee YK, Mukasa R, Hatton RD, et al. Developmental plasticity of Th17 and Treg cells. Curr Opin Immunol 2009; 21: 274.
34. Vanaudenaerde BM, Dupont LJ, Wuyts WA, et al. The role of interleukin-17 during acute rejection after lung transplantation. Eur Respir J 2006; 27:779.
35. Hilliard BA, Kamoun M, Ventura E, et al. Mechanisms of suppression of experimental autoimmune encephalomyelitis by intravenous administration of myelin basic protein: Role of regulatory spleen cells. Exp Mol Pathol 2000; 68: 29.
36. Langrish CL, Chen Y, Blumenschein WM, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005; 201: 233.
37. KoendersMI, KollsJK, Oppers-Walgreen B, et al. Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis. Arthritis Rheum 2005; 52: 3239.
38. Vanaudenaerde BM, De Vleeschauwer SI, Vos R, et al. The role of the IL23/IL17 axis in bronchiolitis obliterans syndrome after lung transplantation. Am J Transplant 2008; 8: 1911.
39. Stumhofer JS, Hunter CA. Advances in understanding the antiinflammatory properties of IL-27. Immunol Lett 2008; 117: 123.
40. Bobadilla JL, Love RB, Jankowska-Gan E, et al. TH-17, monokines, collagen type v, and primary graft dysfunction in lung transplantation. Am J Respir Crit Care Med 2008; 177: 660.
41. Mills KH. Induction, function and regulation of IL-17-producing T cells. Eur J Immunol 2008; 38: 2636.
42. Messi M, Giacchetto I, Nagata K, et al. Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytes. Nat Immunol 2003; 4: 78.
43. + T cells prevents development of experimental autoimmune diseases. J Immunol 2008; 180: 6070.
44. + regulatory T cells prevent autoimmunity by inhibiting dendritic cells from activating autoreactive T cells. J Immunol 2007; 179: 4685.
45. Stockinger B, Veldhoen M. Differentiation and function of Th17 T cells. Curr Opin Immunol 2007; 19: 281.
46. + T cells. J Immunol 2006; 176: 6202.
47. Stummvoll GH, DiPaolo RJ, Huter EN, et al. Th1, Th2, and Th17 effector T cell-induced autoimmune gastritis differs in pathological pattern and in susceptibility to suppression by regulatory T cells. JIm-munol2008; 181: 1908.
48. Korn T, Reddy J, Gao W, et al. Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nat Med2007; 13:423.
49. +CD25~Foxp3~ T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta. J Immunol 2007; 178: 6725.
50. Muthukumar T, Dadhania D, Ding R, et al. Messenger RNA for FOXP3 in the urine of renal-allograft recipients. NEngl J Med 2005; 353: 2342.
51. YangH, DingR, SharmaVK, etal. HyperexpressionofFoxp3 andIDO during acute rejection of islet allografts. Transplantation 2007; 83:1643.
52. Mitchell P, Afzali B, Lombardi G, et al. The T helper 17-regulatory T cell axis in transplant rejection and tolerance. Curr Opin Organ Transplant 2009; 14:326.
53. Beriou G, Costantino CM, Ashley CW, et al. IL-17-producing human peripheral regulatory T cells retain suppressive function. Blood 2009; 113: 4240.
54. Zheng XX, Sanchez-Fueyo A, Sho M, et al. Favorably tipping the balance between cytopathic and regulatory T cells to create transplantation tolerance. Immunity 2003; 19: 503.