메뉴 건너뛰기




Volumn 31, Issue 1, 2011, Pages 45-52

The role of ERK1/2 in 15-HETE-inhibited apoptosis in pulmonary arterial smooth muscle cells

Author keywords

15 Hydroxyeicosatetrenoic acid; Apoptosis; ERK; Pulmonary artery muscle smooth cells

Indexed keywords

15 HYDROXYICOSATETRAENOIC ACID; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATASE; PROTEIN BCL 2; TENSIN;

EID: 78650766586     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.3109/10799893.2010.512013     Document Type: Article
Times cited : (24)

References (29)
  • 1
    • 4644290657 scopus 로고    scopus 로고
    • Treatment of pulmonary arterial hypertension
    • Humbert M, Sitbon O, Simonneau G. Treatment of pulmonary arterial hypertension. N Engl J Med 2004, 351, 1425-1436.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 1425-1436
    • Humbert, M.1    Sitbon, O.2    Simonneau, G.3
  • 2
    • 4143118866 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of pulmonary vascular remodeling: Role in the development of pulmonary hypertension
    • Mandegar M, Fung YC, Huang W, Remillard CV, Rubin LJ, Yuan JX. Cellular and molecular mechanisms of pulmonary vascular remodeling: role in the development of pulmonary hypertension. Microvasc Res 2004, 68, 75-103.
    • (2004) Microvasc. Res. , vol.68 , pp. 75-103
    • Mandegar, M.1    Fung, Y.C.2    Huang, W.3    Remillard, C.V.4    Rubin, L.J.5    Yuan, J.X.6
  • 4
    • 0031671673 scopus 로고    scopus 로고
    • Elastase and the pathobiology of unexplained pulmonary hypertension
    • Rabinovitch M. Elastase and the pathobiology of unexplained pulmonary hypertension. Chest 1998, 114, 213S-224S.
    • (1998) Chest , vol.114
    • Rabinovitch, M.1
  • 6
    • 0029043582 scopus 로고
    • How MAP kinases are regulated
    • Cobb MH, Goldsmith EJ. How MAP kinases are regulated. J Biol Chem 1995, 270, 14843-14846.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14843-14846
    • Cobb, M.H.1    Goldsmith, E.J.2
  • 8
    • 0037077253 scopus 로고    scopus 로고
    • Notch3 signaling in vascular smooth muscle cells induces c-FLIP expression via ERK/MAPK activation
    • Wang W, Prince CZ, Mou Y, Pollman MJ. Notch3 signaling in vascular smooth muscle cells induces c-FLIP expression via ERK/MAPK activation. JBC 2002, 277, 21723-21729.
    • (2002) JBC , vol.277 , pp. 21723-21729
    • Wang, W.1    Prince, C.Z.2    Mou, Y.3    Pollman, M.J.4
  • 11
    • 39749112553 scopus 로고    scopus 로고
    • BMP suppresses PTEN expression via RAS/ERK signaling
    • Beck SE, Carethers JM. BMP suppresses PTEN expression via RAS/ERK signaling. Cancer Biol Ther 2007, 6, 1313-1317.
    • (2007) Cancer Biol. Ther. , vol.6 , pp. 1313-1317
    • Beck, S.E.1    Carethers, J.M.2
  • 12
    • 7244243972 scopus 로고    scopus 로고
    • Oxidants inhibit ERK/MAPK and prevent its ability to delay neutrophil apoptosis downstream of mitochondrial changes and at the level of XIAP
    • Gardai SJ, Whitlock BB, Xiao YQ, Bratton DB, Henson PM. Oxidants inhibit ERK/MAPK and prevent its ability to delay neutrophil apoptosis downstream of mitochondrial changes and at the level of XIAP. J Biol Chem 2004, 279, 44695-44703.
    • (2004) J. Biol. Chem. , vol.279 , pp. 44695-44703
    • Gardai, S.J.1    Whitlock, B.B.2    Xiao, Y.Q.3    Bratton, D.B.4    Henson, P.M.5
  • 13
    • 0037687982 scopus 로고    scopus 로고
    • Chronic hypoxia activates lung 15-lipoxygenase, which catalyzes production of 15-HETE and enhances constriction in neonatal rabbit pulmonary arteries
    • Zhu D, Medhora M, Campbell WB, Spitzbarth N, Baker JE, Jacobs ER. Chronic hypoxia activates lung 15-lipoxygenase, which catalyzes production of 15-HETE and enhances constriction in neonatal rabbit pulmonary arteries. Circ Res 2003, 92, 992-1000.
    • (2003) Circ Res. , vol.92 , pp. 992-1000
    • Zhu, D.1    Medhora, M.2    Campbell, W.B.3    Spitzbarth, N.4    Baker, J.E.5    Jacobs, E.R.6
  • 15
    • 33846965975 scopus 로고    scopus 로고
    • Role of 15-hydroxyeicosatetraenoic acid in phosphorylation of ERK1/2 and caldesmon in pulmonary arterial smooth muscle cells
    • Lu C, Liu Y, Tang X, Ye H, Zhu D. Role of 15-hydroxyeicosatetraenoic acid in phosphorylation of ERK1/2 and caldesmon in pulmonary arterial smooth muscle cells. Can J Physiol Pharmacol 2006, 84, 1061-1069.
    • (2006) Can J. Physiol. Pharmacol. , vol.84 , pp. 1061-1069
    • Lu, C.1    Liu, Y.2    Tang, X.3    Ye, H.4    Zhu, D.5
  • 16
    • 44149086360 scopus 로고    scopus 로고
    • Subacute hypoxia suppresses Kv3.4 channel expression and whole-cell K+ currents through endogenous 15-hydroxyeicosatetraenoic acid in pulmonary arterial smooth muscle cells
    • Guo L, Tang X, Tian H, Liu Y, Wang Z, Wu H, Wang J, Guo S, Zhu D. Subacute hypoxia suppresses Kv3.4 channel expression and whole-cell K+ currents through endogenous 15-hydroxyeicosatetraenoic acid in pulmonary arterial smooth muscle cells. Eur J Pharmacol 2008, 587, 187-195.
    • (2008) Eur. J. Pharmacol. , vol.587 , pp. 187-195
    • Guo, L.1    Tang, X.2    Tian, H.3    Liu, Y.4    Wang, Z.5    Wu, H.6    Wang, J.7    Guo, S.8    Zhu, D.9
  • 17
    • 44249108050 scopus 로고    scopus 로고
    • 20-Hydroxyeicosatetraenoic acid inhibits the apoptotic responses in pulmonary artery smooth muscle cells
    • Wang Z, Tang X, Li Y, Leu C, Guo L, Zheng X, Zhu D. 20- Hydroxyeicosatetraenoic acid inhibits the apoptotic responses in pulmonary artery smooth muscle cells. Eur J Pharmacol 2008, 588, 9-17.
    • (2008) Eur. J. Pharmacol. , vol.588 , pp. 9-17
    • Wang, Z.1    Tang, X.2    Li, Y.3    Leu, C.4    Guo, L.5    Zheng, X.6    Zhu, D.7
  • 18
    • 0033048656 scopus 로고    scopus 로고
    • Cell cycle regulatory molecules cyclins cyclindependent kinases and cyclin-dependent kinase inhibitors and the cardiovascular system potential targets for therapy
    • Li JM, Brooks G. Cell cycle regulatory molecules (cyclins, cyclindependent kinases and cyclin-dependent kinase inhibitors) and the cardiovascular system; potential targets for therapy? Eur Heart J 1999, 20, 406-420.
    • (1999) Eur. Heart J. , vol.20 , pp. 406-420
    • Li, J.M.1    Brooks, G.2
  • 19
    • 36348934636 scopus 로고    scopus 로고
    • Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members
    • Chen M, Guerrero AD, Huang L, Shabier Z, Pan M, Tan TH, Wang J. Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members. J Biol Chem 2007, 282, 33888-33895.
    • (2007) J. Biol. Chem. , vol.282 , pp. 33888-33895
    • Chen, M.1    Guerrero, A.D.2    Huang, L.3    Shabier, Z.4    Pan, M.5    Tan, T.H.6    Wang, J.7
  • 20
    • 1642499403 scopus 로고    scopus 로고
    • Suppression of PTEN expression by NF-kappa B prevents apoptosis
    • Vasudevan KM, Gurumurthy S, Rangnekar VM. Suppression of PTEN expression by NF-kappa B prevents apoptosis. Mol Cell Biol 2004, 24, 1007-1021.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 1007-1021
    • Vasudevan, K.M.1    Gurumurthy, S.2    Rangnekar, V.M.3
  • 21
    • 34547606512 scopus 로고    scopus 로고
    • Role of ERK1/2 signaling pathways in 4-aminopyridine-induced rat pulmonary vasoconstriction
    • DOI 10.1016/j.ejphar.2007.04.042, PII S0014299907005201
    • Han W, Tang X, Wu H, Liu Y, Zhu D. Role of ERK1/2 signaling pathways in 4-aminopyridine-induced rat pulmonary vasoconstriction. Eur J Pharmacol 2007, 569, 138-144. (Pubitemid 47189561)
    • (2007) European Journal of Pharmacology , vol.569 , Issue.1-2 , pp. 138-144
    • Han, W.1    Tang, X.2    Wu, H.3    Liu, Y.4    Zhu, D.5
  • 23
    • 6344257102 scopus 로고    scopus 로고
    • Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis
    • McMurtry MS, Bonnet S, Wu X, Dyck JR, Haromy A, Hashimoto K, Michelakis ED. Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis. Circ Res 2004, 95, 830-840.
    • (2004) Circ Res. , vol.95 , pp. 830-840
    • McMurtry, M.S.1    Bonnet, S.2    Wu, X.3    Dyck, J.R.4    Haromy, A.5    Hashimoto, K.6    Michelakis, E.D.7
  • 25
    • 0343621512 scopus 로고    scopus 로고
    • The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase
    • Wang X, Gjörloff-Wingren A, Saxena M, Pathan N, Reed JC, Mustelin T. The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase. J Immunol 2000, 164, 1934-1939.
    • (2000) J. Immunol. , vol.164 , pp. 1934-1939
    • Wang, X.1    Gjörloff-Wingren, A.2    Saxena, M.3    Pathan, N.4    Reed, J.C.5    Mustelin, T.6
  • 26
    • 0037098951 scopus 로고    scopus 로고
    • PTEN blocks insulin-mediated ETS-2 phosphorylation through map kinase independently of the phosphoinositide 3-kinase pathway
    • Weng LP, Brown JL, Baker KM, Ostrowski MC, Eng C. PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway. Hum Mol Genet 2002, 11, 1687-1696.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 1687-1696
    • Weng, L.P.1    Brown, J.L.2    Baker, K.M.3    Ostrowski, M.C.4    Eng, C.5
  • 27
    • 0032583122 scopus 로고    scopus 로고
    • Tumor suppressor PTEN inhibits integrin-and growth factor-mediated mitogen-activated protein map kinase signaling pathways
    • Gu J, Tamura M, Yamada KM. Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways. J Cell Biol 1998, 143, 1375-1383.
    • (1998) J. Cell. Biol. , vol.143 , pp. 1375-1383
    • Gu, J.1    Tamura, M.2    Yamada, K.M.3
  • 28
    • 0033082995 scopus 로고    scopus 로고
    • IAP family proteins-suppressors of apoptosis
    • Deveraux QL, Reed JC. IAP family proteins-suppressors of apoptosis. Genes Dev 1999, 13, 239-252.
    • (1999) Genes Dev. , vol.13 , pp. 239-252
    • Deveraux, Q.L.1    Reed, J.C.2
  • 29
    • 50649111640 scopus 로고    scopus 로고
    • Impact of protein kinase CK2 on inhibitor of apoptosis proteins in prostate cancer cells
    • Wang G, Ahmad KA, Harris NH, Ahmed K. Impact of protein kinase CK2 on inhibitor of apoptosis proteins in prostate cancer cells. Mol Cell Biochem 2008, 316, 91-97.
    • (2008) Mol. Cell. Biochem. , vol.316 , pp. 91-97
    • Wang, G.1    Ahmad, K.A.2    Harris, N.H.3    Ahmed, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.