Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK

Molecular and Cellular Biochemistry

Volumn 269, Issue 1, 2005, Pages 109-114

  Nishida, Shozo ^a   Matsuoka, Hiroshi ^b   Tsubaki, Masanobu ^a   Tanimori, Yoshihiro ^a   Yanae, Masasi ^a   Fujii, Yoshiki ^a   Iwaki, Masahiro ^a  

^a KINKI UNIVERSITY   (Japan)

^b KINDAI UNIVERSITY NARA HOSPITAL   (Japan)

Author keywords

Apoptosis; ERK; Mevastatin; Statin

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ADENINE DERIVATIVE; ANTINEOPLASTIC AGENT; COMPACTIN; FARNESYL DIPHOSPHATE; GERANYLGERANYL PYROPHOSPHATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2; PROTEIN KINASE B; SQUALENE; UBIQUINONE;

APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL NUCLEUS; CELL STRAIN HL 60; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BUTADIENES; CASPASE 3; CASPASES; CELL NUCLEUS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HL-60 CELLS; HUMANS; LOVASTATIN; NITRILES; PHOSPHORYLATION; POLYISOPRENYL PHOSPHATES; PROTEIN KINASE INHIBITORS;

EID: 14244266579     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11010-005-3086-0     Document Type: Article

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