Oral silicon supplementation: An effective therapy for preventing oral aluminum absorption and retention in mammals

Nutrition Reviews

Volumn 69, Issue 1, 2011, Pages 41-51

  Domingo, José L ^a   Gómez, Mercedes ^a   Colomina, M Teresa ^a  

^a UNIVERSITAT ROVIRA I VIRGILI   (Spain)

Author keywords

Aluminum; Drinking water; Interactions; Mammals; Silicon

Indexed keywords

ALUMINUM; SILICON;

ALUMINUM METABOLISM; ALZHEIMER DISEASE; ARTICLE; BRAIN; COGNITION; DIET SUPPLEMENTATION; HUMAN; MAMMAL; NONHUMAN;

ADMINISTRATION, ORAL; ALUMINUM; ALZHEIMER DISEASE; BRAIN; DIETARY SUPPLEMENTS; HUMANS; INTESTINAL ABSORPTION; SILICON;

MAMMALIA;

EID: 78650761517     PISSN: 00296643     EISSN: 17534887     Source Type: Journal    
DOI: 10.1111/j.1753-4887.2010.00360.x     Document Type: Article

References (96)

1. Poole RL, Hintz SR, Mackenzie NI, Kerner JA Jr. Aluminum exposure from pediatric parenteral nutrition: meeting the new FDA regulation. JPEN J Parenter Enteral Nutr. 2008;32:242-246.
2. Poole RL, Schiff L, Hintz SR, Wong A, Mackenzie N, Kerner JA Jr. Aluminum content of parenteral nutrition in neonates: measured versus calculated levels. J Pediatr Gastroenterol Nutr. 2010;50:208-211.
3. Saiyed SM, Yokel RA. Aluminum content of some foods and food products in the USA, with aluminum food additives. Food Addit Contam. 2005;22:234-244.
4. World Health Organization. Aluminum-Environmental Health Criteria, Vol 194. Geneva, Switzerland: World Health Organization; 1997:1-152.
5. Yokel RA, Florence RL. Aluminum bioavailability from the approved food additive leavening agent acidic sodium aluminum phosphate, incorporated into a baked good, is lower than from water. Toxicology. 2006;227:86-93.
6. Yokel RA, Florence RL. Aluminum bioavailability from tea infusion. Food Chem Toxicol. 2008;46:3659-3663.
7. Savory J, Huang Y, Herman MM, Reyes MR, Wills MR. Tau immunoreactivity associated with aluminum maltolate-induced neurofibrillary degeneration in rabbits. Brain Res. 1995;669:325-329.
8. Savory J, Herman MM, Ghribi O. Mechanisms of aluminum-induced neurodegeneration in animals: implications for Alzheimer's disease. J Alzheimers Dis. 2006;10:135-144.
9. McLachlan DR, Bergeron C, Smith JE, Boomer D, Rifat SL. Risk for neuropathologically confirmed Alzheimer's disease and residual aluminum in municipal drinking water employing weighted residential histories. Neurology. 1996;46:401-405.
10. Altmann P, Cunningham J, Dhanesha U, Ballard M, Thompson J, Marsh F. Disturbance of cerebral function in people exposed to drinking water contaminated with aluminum sulphate: retrospective study of the Camelford water incident. BMJ. 1999;25:807-811.
11. Gauthier E, Fortier I, Courchesne F, Pepin P, Mortimer J, Gauvreau D. Aluminum forms in drinking water and risk of Alzheimer's disease. Environ Res. 2000;3:234-246.
12. Flaten TP. Aluminum as a risk factor in Alzheimer's disease, with emphasis on drinking water. Brain Res Bull. 2001;55:187-196.
13. Exley C, Esiri MM. Severe cerebral congophilic angiopathy coincident with increased brain aluminum in a resident of Camelford, Cornwall, UK. J Neurol Neurosurg Psychiatry. 2006;77:877-879.
14. Rifat SL, Eastwood MR, McLachlan DR, Corey PN. Effect of exposure of miners to aluminum powder. Lancet. 1990;336:1162-1165.
15. Polizzi S, Pira E, Ferrara M, et al. Neurotoxic effects of aluminum among foundry workers and Alzheimer's disease. Neurotoxicology. 2002;23:761-774.
16. Giorgianni C, Faranda M, Brecciaroli R, et al. Cognitive disorders among welders exposed to aluminum. G Ital Med Lav Ergon. 2003;25:102-103.
17. Kawahara M. Effects of aluminum on the nervous system and its possible link with neurodegenerative diseases. J Alzheimers Dis. 2005;8:171-182.
18. Pratico D, Uryu K, Sung S, Tang S, Trojanowski JQ, Lee VM. Aluminum modulates brain amyloidosis through oxidative stress in APP transgenic mice. FASEB J. 2002;16:1138-1140.
19. Esparza JL, Gomez M, Romeu M, et al. Aluminum-induced pro-oxidant effects in rats: protective role of exogenous melatonin. J Pineal Res. 2003;35:32-39.
20. Esparza JL, Gomez M, Nogues MR, Paternain JL, Mallol J, Domingo JL. Melatonin reduces oxidative stress and increases gene expression in the cerebral cortex and cerebellum of aluminum exposed-rats. J Pineal Res. 2005;39:129-136.
21. Szutowicz A. Aluminum, NO, and nerve growth factor neurotoxicity in cholinergic neurons. J Neurosci Res. 2001;66:1009-1018.
22. Ghribi O, Herman MM, Forbes MS, DeWitt DA, Savory J. GDNF protects against aluminum-induced apoptosis in rabbits by upregulating Bcl-2 and Bcl-XL and inhibiting mitochondrial Bax translocation. Neurobiol Dis. 2001;8:764-773.
23. Rodella LF, Ricci F, Borsani E, et al. Aluminum exposure induces Alzheimer's disease-like histopathological alterations in mouse brain. Histol Histopathol. 2008;23:433-439.
24. Krewski D, Yokel RA, Nieboer E, et al. Human health risk assessment for aluminum, aluminum oxide, and aluminum hydroxide. J Toxicol Environ Health B Crit Rev. 2007;10:1-269.
25. Golub MS, Germann SL, Han B, Keen CL. Lifelong feeding of a high aluminum diet to mice. Toxicology. 2000;50:107-117.
26. Roig JL, Fuentes S, Colomina MT, Vicens P, Domingo JL. Aluminum, restraint stress and aging: behavioral effects in rats after 1 and 2 years of aluminum exposure. Toxicology. 2006;218:112-124.
27. Strong MJ. Aluminum neurotoxicity: an experimental approach to the induction of neurofilamentous inclusions. J Neurol Sci. 1994;124(Suppl):S20-S26.
28. Exley C. The pro-oxidant activity of aluminum. Free Radic Biol Med. 2004;36:380-387.
29. Gómez M, Esparza JL, Nogués MR, Giralt M, Domingo JL. Pro-oxidant activity of aluminum in the rat hippocampus: gene expression of antioxidant enzymes after melatonin administration. Free Radic Biol Med. 2005;38:104-111.
30. Shcherbatykh I, Carpenter DO. The role of metals in the etiology of Alzheimer's disease. J Alzheimers Dis. 2007;11:191-205.
31. Walton JR. An aluminum-based rat model for Alzheimer's disease exhibits oxidative damage, inhibition of PP2A activity, hyperphosphorylated tau, and granulovacuolar degeneration. J Inorg Biochem. 2007;101:1275-1284.
32. McLachlan DR, Lukiw WJ, Kruck TP. New evidence for an active role of aluminum in Alzheimer' disease. Can J Neurol Sci. 1989;16:490-497.
33. McLachlan DR, Kruck TP, Lukiw WJ, Krishnan SS. Would decreased aluminum ingestion reduce the incidence of Alzheimer' disease? CMAJ. 1991;145:793-804.
34. Yokel RA. The toxicology of aluminum in the brain: a review. Neurotoxicology. 2000;21:813-828.
35. Yumoto S, Kakimi S, Ohsaki A, Ishikawa A. Demonstration of aluminum in amyloid fibers in the cores of senile plaques in the brains of patients with Alzheimer's disease. J Inorg Biochem. 2009;103:1579-1584.
36. Frisardi V, Solfrizzi V, Capurso C, et al. Aluminum in the diet and Alzheimer's disease: from current epidemiology to possible disease-modifying treatment. J Alzheimers Dis. 2010;20:17-30.
37. Bondy SC. The neurotoxicity of environmental aluminum is still an issue. Neurotoxicology. 2010;31:575-581.
38. Domingo JL. Aluminum and other metals in Alzheimer's disease: a review of potential therapy with chelating agents. J Alzheimers Dis. 2006;10:331-341.
39. Yokel RA. Blood-brain barrier flux of aluminum, manganese, iron and other metals suspected to contribute to metal-induced neurodegeneration. J Alzheimers Dis. 2006;10:223-253.
40. Maynard CJ, Cappai R, Volitakis I, et al. Gender and genetic background effects on brain metal levels in APP transgenic and normal mice: implications for Alzheimer beta-amyloid pathology. J Inorg Biochem. 2006;100:952-962.
41. Rondeau V. A review of epidemiologic studies on aluminum and silica in relation to Alzheimer's disease and associated disorders. Rev Environ Health. 2002;17:107-121.
42. Molloy DW, Standish TI, Nieboer E, Turnbull JD, Smith SD, Dubois S. Effects of acute exposure to aluminum on cognition in humans. J Toxicol Environ Health. 2007;70:2011-2019.
43. Yokel RA, Ackrill P, Burgess E, et al. Prevention and treatment of aluminum toxicity including chelation therapy: status and research needs. J Toxicol Environ Health. 1996;48:667-683.
44. Sripanyakorn S, Jugdaohsingh R, Elliott H, et al. The silicon content of beer and its bioavailability in healthy volunteers. Br J Nutr. 2004;91:403-409.
45. Sripanyakorn S, Jugdaohsingh R, Dissayabutr W, Anderson SH, Thompson RP, Powell JJ. The comparative absorption of silicon from different foods and food supplements. Br J Nutr. 2009;102:825-834.
46. Jugdaohsingh R, Anderson SH, Tucker KL, et al. Dietary silicon intake and absorption. Am J Clin Nutr. 2002;75:887-893.
47. Powell JJ, McNaughton SA, Jugdaohsingh R, et al. A provisional database for the silicon content of foods in the United Kingdom. Br J Nutr. 2005;94:804-812.
48. Pérez-Granados AM, Vaquero MP. Silicon, aluminum, arsenic and lithium: essentiality and human health implications. J Nutr Health Aging. 2002;6:154-162.
49. Robberecht H, Van Cauwenbergh R, Van Vlaslaer V, Hermans N. Dietary silicon intake in Belgium: sources, availability from foods, and human serum levels. Sci Total Environ. 2009;407:4777-4782.
50. Fauteux F, Rémus-Borel W, Menzies JG, Bélanger RR. Silicon and plant disease resistance against pathogenic fungi. FEMS Microbiol Lett. 2005;249:1-6.
51. Maurel C. Plant aquaporins: novel functions and regulation properties. FEBS Lett. 2007;581:2227-2236.
52. Fauteux F, Chain F, Belzile F, Menzies JG, Bélanger RR. The protective role of silicon in the Arabidopsis-powdery mildew pathosystem. Proc Natl Acad Sci U S A. 2006;103:17554-17559.
53. Exley C. Silicon in life: whither biological silicification? Prog Mol Subcell Biol. 2009;47:173-184.
54. Kinrade SD, Del Nin JW, Schach AS, et al. Stable five- and six-coordinated silicate anions in aqueous solution. Science. 1999;285:1542-1545.
55. Lambert JB, Lu G, Singer SR, Kolb VM. Silicate complexes of sugars in aqueous solution. J Am Chem Soc. 2004;126:9611-9625.
56. Reffitt DM, Jugdaohsingh R, Thompson RP, Powell JJ. Silicic acid: its gastrointestinal uptake and urinary excretion in man and effects on aluminium excretion. J Inorg Biochem. 1999;76:141-147.
57. Exley C, Pinnegar JK, Taylor H. Hydroxyaluminosilicates and acute aluminum toxicity in fish. J Theor Biol. 1997;189:133-139.
58. Edwardson JA, Moore PB, Ferrier IN, et al. Effect of silicon on gastrointestinal absorption of aluminum. Lancet. 1993;342:211-212.
59. Bellia JP, Birchall JD, Roberts NB. The role of silicic acid in the renal excretion of aluminum. Ann Clin Lab Sci. 1996;26:227-233.
60. Doucet FJ, Rotov ME, Exley C. Direct and indirect identification of the formation of hydroxyaluminosilicates in acidic solutions. J Inorg Biochem. 2001;87:71-79.
61. Exley C, Korchazhkina O, Job D, Strekopytov S, Polwart A, Crome P. Non-invasive therapy to reduce the body burden of aluminum in Alzheimer's disease. J Alzheimers Dis. 2006;10:17-24.
62. Birchall JD, Chappell JS. Aluminum, water chemistry, and Alzheimer's disease. Lancet. 1989;1:953.
63. Taylor GA, Newens AJ, Edwardson JA, Kay DW, Forster DP. Alzheimer's disease and the relationship between silicon and aluminum in water supplies in northern England. J Epidemiol Community Health. 1995;49:323-324.
64. Jacqmin-Gadda H, Commenges D, Letenneur L, Dartigues JF. Silica and aluminum in drinking water and cognitive impairment in the elderly. Epidemiology. 1996;7:281-285.
65. Rondeau V, Commenges D, Jacqmin-Gadda H, Dartigues JF. Relation between aluminum concentrations in drinking water and Alzheimer's disease: an 8-year follow-up study. Am J Epidemiol. 2000;152:59-66.
66. Rondeau V, Jacqmin-Gadda H, Commenges D, Dartigues JF. Aluminum in drinking water and cognitive decline in elderly subjects: the Paquid cohort. Am J Epidemiol. 2001;154:288-290.
67. Martyn CN, Coggon DN, Inskip H, Lacey RF, Young WF. Aluminum concentrations in drinking water and risk of Alzheimer's disease. Epidemiology. 1997;8:281-286.
68. Rondeau V, Jacqmin-Gadda H, Commenges D, Helmer C, Dartigues JF. Aluminum and silica in drinking water and the risk of Alzheimer's disease or cognitive decline: findings from 15-year follow-up of the PAQUID cohort. Am J Epidemiol. 2009;169:489-496.
69. Gillette-Guyonnet S, Andrieu S, Nourhashemi F, Guéronnière V, Grandjean H, Vellas B. Cognitive impairment and composition of drinking water in women: findings of the EPIDOS Study. Am J Clin Nutr. 2005;81:897-902.
70. Gillette-Guyonnet S, Andrieu S, Vellas B. The potential influence of silica present in drinking water on Alzheimer's disease and associated disorders. J Nutr Health Aging. 2007;11:119-124.
71. Birchall JD, Chappell JS. The chemistry of aluminum and silicon in relation to Alzheimer's disease. Clin Chem. 1988;34:265-267.
72. Birchall JD, Exley C, Chappell JS, Phillips MJ. Acute toxicity of aluminum to fish eliminated in silicon-rich acid waters. Nature. 1989;338:146-148.
73. Hammond KE, Evans DE, Hodson MJ. Aluminum/silicon interactions in barley (Hordeum vulgare L.) seedlings. Plant Soil. 1995;173:89-95.
74. Exley C, Schneider C, Doucet FJ. The reaction of aluminum with silicic acid in acidic solution: an important mechanism in controlling the biological availability of aluminum? Coord Chem Rev. 2002;228:127-135.
75. Perry CC, Keeling-Tucker T. Aspects of the bioinorganic chemistry of silicon in conjunction with the biometals calcium, iron and aluminum. J Inorg Biochem. 1998;69:181-191.
76. Perry CC, Keeling-Tucker T. Model studies of the precipitation of silica in the presence of aluminum; implications for biology and industry. J Inorg Biochem. 2000;78:331-339.
77. Candy JM, Oakley AE, Klinowski J, et al. Aluminosilicates and senile plaque formation in Alzheimer's disease. Lancet. 1986;1:354-357.
78. Carlisle EM, Curran MJ. Effect of dietary silicon and aluminum on silicon and aluminum levels in rat brain. Alzheimer Dis Assoc Disord. 1987;1:83-89.
79. Bellés M, Sánchez DJ, Gómez M, Corbella J, Domingo JL. Silicon reduces aluminum accumulation in rats: relevance to the aluminum hypothesis of Alzheimer disease. Alzheimer Dis Assoc Disord. 1998;12:83-87.
80. Birchall JD. The interrelationship between silicon and aluminum in the biological effects of aluminum. Ciba Found Symp. 1992;169:50-61.
81. Drüeke TB, Jouhanneau P, Banide H, Lacour B, Yiou F, Raisbeck G. Effects of silicon, citrate and the fasting state on the intestinal absorption of aluminum in rats. Clin Sci. 1997;92:63-67.
82. Harris WR, Berthon G, Day JP, et al. Speciation of aluminum in biological systems. J Toxicol Environ Health. 1996;48:543-568.
83. Glynn AW, Sparén A, Danielsson LG, Sundström B, Jorhem L. The influence of complexing agents on the solubility and absorption of aluminum in rats exposed to aluminum in water. Food Addit Contam. 2001;18:515-523.
84. Peña A, Meseguer I, González-Muñoz MJ. Influence of moderate beer consumption on aluminum toxico-kynetics: acute study. Nutr Hosp. 2007;22:371-376. (in Spanish).
85. González-Muñoz MJ, Peña A, Meseguer I. Role of beer as a possible protective factor in preventing Alzheimer's disease. Food Chem Toxicol. 2008;46:49-56.
86. Granero S, Vicente M, Aguilar V, Martinez-Para MC, Domingo JL. Effects of beer as a source of dietary silicon on aluminum absorption and retention in mice. Trace Elem Electrolytes. 2004;21:28-32.
87. Gonzalez-Muñoz MJ, Meseguer I, Sanchez-Reus MI, et al. Beer consumption reduces cerebral oxidation caused by aluminum toxicity by normalizing gene expression of tumor necrotic factor alpha and several antioxidant enzymes. Food Chem Toxicol. 2008;46:1111-1118.
88. Bellés M, Albina ML, Sánchez DJ, Domingo JL. Lack of protective effects of dietary silicon on aluminum-induced maternal and developmental toxicity in mice. Pharmacol Toxicol. 1999;85:1-6.
89. Pennington JA. Silicon in foods and diets. Food Addit Contam. 1991;8:97-118.
90. Bellia JP, Birchall JD, Roberts NB. Beer: a dietary source of silicon. Lancet. 1994;343:235.
91. van Dyck K, Robberecht H, Van Cauwenbergh R, Van Vlaslaer V, Deelstra H. Indication of silicon essentiality in humans: serum concentrations in Belgian children and adults, including pregnant women. Biol Trace Elem Res. 2000;77:25-32.
92. Jugdaohsingh R, Reffitt DM, Oldham C, et al. Oligomeric but not monomeric silica prevents aluminum absorption in humans. Am J Clin Nutr. 2000;71:944-949.
93. Exley C, Wicks AJ, Hubert RB, Birchall JD. Polynuclear aluminum and acute aluminum toxicity in the fish. J Theor Biol. 1994;167:415-416.
94. Savory J, Herman MM, Ghribi O. Supplementation of the diet with silicic acid to reduce body burden of aluminum: a miracle cure or useless treatment for Alzheimer's disease? J Alzheimers Dis. 2006;10:25-27.
95. Fasman GD, Moore CD. The solubilization of model Alzheimer tangles: reversing the beta-sheet conformation induced by aluminum with silicates. Proc Natl Acad Sci USA. 1994;91:11232-11235.
96. Fasman GD, Perczel A, Moore CD. Solubilization of beta-amyloid-(1-42)-peptide: reversing the beta-sheet conformation induced by aluminum with silicates. Proc Natl Acad Sci USA. 1995;92:369-371.