Effect of dextromethorphan on human Kv1.3 channel activity: Involvement of C-type inactivation

European Journal of Pharmacology

Volumn 651, Issue 1-3, 2011, Pages 122-127

  Lee, Jun Ho ^a   Choi, Sun Hye ^b   Shin, Tae Joon ^b   Lee, Byung Hwan ^b   Hwang, Sung Hee ^b   Kim, Hyoung Chun ^c   Nah, Seung Yeol ^b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Konkuk University   (South Korea)

^c Kangwon National University   (South Korea)

Author keywords

C type inactivation; Dextromethorphan; Kv1.3 channel; Xenopus oocyte

Indexed keywords

DEXTROMETHORPHAN; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KV1.2; POTASSIUM CHANNEL KV1.3; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; FEMALE; HETEROLOGOUS EXPRESSION; MOLECULAR MECHANICS; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PRIORITY JOURNAL; STEADY STATE; VOLTAGE CLAMP; XENOPUS LAEVIS;

ANIMALS; DEXTROMETHORPHAN; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC CONDUCTIVITY; HUMANS; KINETICS; KV1.2 POTASSIUM CHANNEL; KV1.3 POTASSIUM CHANNEL; NEUROPROTECTIVE AGENTS;

EID: 78650676939     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.10.091     Document Type: Article

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