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Volumn 3, Issue 1, 2011, Pages 79-94

Early development of sigma-receptor ligands

Author keywords

[No Author keywords available]

Indexed keywords

4 METHYL 1 (3 PHENYLPROPYL)PIPERIDINE; ANTINEOPLASTIC AGENT; ANXIOLYTIC AGENT; BUTYROPHENONE DERIVATIVE; CALCIUM ION; CB 184; CB 64D; CHOLINERGIC RECEPTOR BLOCKING AGENT; CYCLAZOCINE; DEXTROMETHORPHAN; GEMCITABINE; HALOPERIDOL; LEVORPHANOL; LIGAND; MORPHINE; N [2 (3,4 DICHLOROPHENYL)ETHYL] N METHYL 2 (1 PYRROLIDINYL)ETHYLAMINE; N ALLYLNORMETAZOCINE; N CYCLOHEXYL N ETHYL 3 (3 CHLORO 4 CYCLOHEXYLPHENYL) 2 PROPENYLAMINE; NALOXONE; NEUROSTEROID; OCTAHYDROBENZO[F]QUINOLINE; OPIATE AGONIST; PACLITAXEL; PB 28; PHENOTHIAZINE DERIVATIVE; PHENYLALKYLPIPERAZINE; POTASSIUM ION; SIGMA 1 OPIATE RECEPTOR; SIGMA 2 OPIATE RECEPTOR; SIRAMESINE; SSR 125329A; SV 119; THIOXANTHENE DERIVATIVE; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG; WC 26;

EID: 78650664286     PISSN: 17568919     EISSN: None     Source Type: Journal    
DOI: 10.4155/fmc.10.279     Document Type: Review
Times cited : (44)

References (121)
  • 1
    • 0017064976 scopus 로고
    • The effects of morphine- and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog
    • Martin WR, Eades CG, Thompson JA, Huppler RE, Gilbert PE. The effects of morphine- and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog. J. Pharmacol. Exp. Ther. 197, 517-532 (1976).
    • (1976) J. Pharmacol. Exp. Ther. , vol.197 , pp. 517-532
    • Martin, W.R.1    Eades, C.G.2    Thompson, J.A.3    Huppler, R.E.4    Gilbert, P.E.5
  • 2
    • 0026543326 scopus 로고
    • The m-opioid activity of k-opioid receptor agonist compounds in the guinea pig ileum
    • Berzetei-Gurske IP, Toll L. The m-opioid activity of k-opioid receptor agonist compounds in the guinea pig ileum. Eur. J. Pharmacol. 212, 283-286 (1992).
    • (1992) Eur. J. Pharmacol. , vol.212 , pp. 283-286
    • Berzetei-Gurske, I.P.1    Toll, L.2
  • 3
    • 0021284195 scopus 로고
    • S receptors mediated the psychotomimetic effects of N-allylnormetazocine (SKF-10,047), but not its opioid agonistic-antagonistic properties.
    • Khazan N, Young GA, El-Fakany EE, Hong O, Calligaro D. s receptors mediated the psychotomimetic effects of N-allylnormetazocine (SKF-10,047), but not its opioid agonistic-antagonistic properties. Neuropharmacology 23, 983-987 (1984).
    • (1984) Neuropharmacology , vol.23 , pp. 983-987
    • Khazan, N.1    Young, G.A.2    El-Fakany, E.E.3    Hong, O.4    Calligaro, D.5
  • 4
    • 0020619765 scopus 로고
    • Naltrexone fails to antagonize the s effects of PCP and SKF 10 47 in the dog
    • Vaupel DB. Naltrexone fails to antagonize the s effects of PCP and SKF 10,047 in the dog. Eur. J. Pharmacol. 92, 269-274 (1983).
    • (1983) Eur. J. Pharmacol. , vol.92 , pp. 269-274
    • Vaupel, D..1
  • 5
    • 0019523684 scopus 로고
    • Locomotor activity and antinociception after putative m k and s opioid receptor agonists in the rat: Influence of dopaminergic agonists and antagonists
    • Iwamoto ET. Locomotor activity and antinociception after putative m, k and s opioid receptor agonists in the rat: influence of dopaminergic agonists and antagonists. J. Pharmacol. Exp. Ther. 217, 451-460 (1981).
    • (1981) J. Pharmacol. Exp. Ther. , vol.217 , pp. 451-460
    • Iwamoto, E.T.1
  • 6
    • 0021743167 scopus 로고
    • Differential neuropharmacological effects of m k and s opioid agonists on cortical EEG power spectra in the rat Stereospecificity and naloxone antagonism
    • Young GA, Khazan N. Differential neuropharmacological effects of m, k and s opioid agonists on cortical EEG power spectra in the rat. Stereospecificity and naloxone antagonism. Neuropharmacology 23, 1161-1165 (1984).
    • (1984) Neuropharmacology , vol.23 , pp. 1161-1165
    • Young, G.A.1    Khazan, N.2
  • 7
    • 0023818680 scopus 로고
    • 3H MK-801 labels a site on the N-methyl-d-aspartate receptor channel complex in rat brain membranes
    • Wong EHF, Knight AR, Woodruff GN. [3H] MK-801 labels a site on the N-methyl-d-aspartate receptor channel complex in rat brain membranes. J. Neurochem. 50, 274-281 (1988).
    • (1988) J. Neurochem. , vol.50 , pp. 274-281
    • Wong, E.H.F.1    Knight, A.R.2    Woodruff, G.N.3
  • 8
    • 0026567933 scopus 로고
    • A proposal for the classification of s binding sites
    • Quirion R, Bowen WD, Itzhak Y et al. A proposal for the classification of s binding sites. Trends Pharmacol. Sci. 13, 85-86 (1992).
    • (1992) Trends Pharmacol. Sci. , vol.13 , pp. 85-86
    • Quirion, R.1    Bowen, W.D.2    Itzhak, Y.3
  • 9
    • 0037171847 scopus 로고    scopus 로고
    • The s receptor as a ligand-regulated auxiliary potassium channel subunit
    • Aydar E, Palmer CP, Klyachko VA, Jackson MB. The s receptor as a ligand-regulated auxiliary potassium channel subunit. Neuron 34, 399-410 (2002).
    • (2002) Neuron , vol.34 , pp. 399-410
    • Aydar, E.1    Palmer, C.P.2    Klyachko, V.A.3    Jackson, M.B.4
  • 10
    • 0030800651 scopus 로고    scopus 로고
    • Purification and characterization of the human SR 31747A-binding protein a nuclear membrane protein related to yeast sterol isomerase
    • Jbilo O, Vidal H, Paul R et al. Purification and characterization of the human SR 31747A-binding protein. A nuclear membrane protein related to yeast sterol isomerase. J. Biol. Chem. 272, 27107-27115 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 27107-27115
    • Jbilo, O.1    Vidal, H.2    Paul, R.3
  • 11
    • 0029797712 scopus 로고    scopus 로고
    • Purification molecular cloning and expression of the mammalian s1-binding site
    • USA
    • Hanner M, Moebius FF, Flandorfer A et al. Purification, molecular cloning and expression of the mammalian s1-binding site. Proc. Natl. Acad. Sci. USA 93, 8072-8077 (1996).
    • (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 8072-8077
    • Hanner, M.1    Moebius, F.F.2    Flandorfer, A.3
  • 12
    • 0035427616 scopus 로고    scopus 로고
    • Molecular cloning and pharmacological characterization of the rat s1 receptor
    • Mei J, Pasternak GW. Molecular cloning and pharmacological characterization of the rat s1 receptor. Biochem. Pharmacol. 62, 349-355 (2001).
    • (2001) Biochem. Pharmacol. , vol.62 , pp. 349-355
    • Mei, J.1    Pasternak, G.W.2
  • 14
    • 0031577794 scopus 로고    scopus 로고
    • Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 s receptor
    • Seth P, Leibach FH, Ganapathy V. Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 s receptor. Biochem. Biophys. Res. Commun. 241, 535-540 (1997).
    • (1997) Biochem. Biophys. Res. Commun. , vol.241 , pp. 535-540
    • Seth, P.1    Leibach, F.H.2    Ganapathy, V.3
  • 16
    • 0028864537 scopus 로고
    • Inotropic action of s receptor ligands in isolated cardiac myocytes from adult rats
    • Novakova M, Ela C, Barg J, Vogel Z, Hasin Y, Eilam Y. Inotropic action of s receptor ligands in isolated cardiac myocytes from adult rats. Eur. J. Pharmacol. 286, 19-30 (1995).
    • (1995) Eur. J. Pharmacol. , vol.286 , pp. 19-30
    • Novakova, M.1    Ela, C.2    Barg, J.3    Vogel, Z.4    Hasin, Y.5    Eilam, Y.6
  • 17
    • 0343924591 scopus 로고    scopus 로고
    • Differential localization of three distinct binding sites for s receptor ligands in rat spleen
    • Wolfe SA Jr, Ha BK, Whitlock BB, Saini P. Differential localization of three distinct binding sites for s receptor ligands in rat spleen. J. Neuroimmun. 72, 45-58 (1997).
    • (1997) J. Neuroimmun. , vol.72 , pp. 45-58
    • Wolfe Jr., S.A.1    Ha, B.K.2    Whitlock, B.B.3    Saini, P.4
  • 18
    • 0034080806 scopus 로고    scopus 로고
    • S receptors: Recent advances and new clinical potentials
    • Bowen WD. s receptors: recent advances and new clinical potentials. Pharm. Acta Helv. 74, 211-218 (2000).
    • (2000) Pharm. Acta Helv. , vol.74 , pp. 211-218
    • Bowen, W.D.1
  • 19
    • 0035895206 scopus 로고    scopus 로고
    • Regulating ankyrin dynamics: Roles of s-1 receptors
    • USA
    • Hayashi T, Su TP. Regulating ankyrin dynamics: roles of s-1 receptors. Proc. Natl. Acad. Sci. USA 98, 491-496 (2001).
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , pp. 491-496
    • Hayashi, T.1    Su, T.P.2
  • 20
    • 35549006797 scopus 로고    scopus 로고
    • S-1 receptor chaperones at ER-mitochondria interface regulate calcium signaling and cell survival
    • Hayashi T, Su TP. s-1 receptor chaperones at ER-mitochondria interface regulate calcium signaling and cell survival. Cell 131, 596-610 (2007).
    • (2007) Cell. , vol.131 , pp. 596-610
    • Hayashi, T.1    Su, T.P.2
  • 21
    • 0034085467 scopus 로고    scopus 로고
    • Ca2+ signalling via s1-receptors: Novel regulatory mechanism affecting intracellular Ca2+ concentration
    • Hayashi T, Maurice T, Su TP. Ca2+ signalling via s1-receptors: novel regulatory mechanism affecting intracellular Ca2+ concentration. J. Pharmacol. Exp. Ther. 293, 788-798 (2000).
    • (2000) J. Pharmacol. Exp. Ther. , vol.293 , pp. 788-798
    • Hayashi, T.1    Maurice, T.2    Su, T.P.3
  • 22
    • 0025228974 scopus 로고
    • N-Methyl-d -aspartate-induced neuronal activation is selectively modulated by s receptors
    • Monnet FP, Debonnel G, Junien JL, De Montigny C. N-Methyl-d -aspartate-induced neuronal activation is selectively modulated by s receptors. Eur. J. Pharmacol. 179, 441-445 (1990).
    • (1990) Eur. J. Pharmacol. , vol.179 , pp. 441-445
    • Monnet, F.P.1    Debonnel, G.2    Junien, J.L.3    De Montigny, C.4
  • 23
    • 0033863418 scopus 로고    scopus 로고
    • Is a nitrogen atom an important pharmacophoric element in s ligand binding
    • Ablordeppey SY, Fischer JB, Glennon RA. Is a nitrogen atom an important pharmacophoric element in s ligand binding? Bioorg. Med. Chem. 8, 2105-2111 (2000).
    • (2000) Bioorg. Med. Chem. , vol.8 , pp. 2105-2111
    • Ablordeppey, S.Y.1    Fischer, J.B.2    Glennon, R.A.3
  • 27
    • 36248941186 scopus 로고    scopus 로고
    • Smolders I s-1 receptor-mediated increase in hippocampal extracellular dopamine contributes to the mechanism of the anticonvulsant action of neuropeptide Y
    • Muers A, Clinkers R, Ebinger G, Michotte Y, Smolders I. s-1 receptor-mediated increase in hippocampal extracellular dopamine contributes to the mechanism of the anticonvulsant action of neuropeptide Y. Eur. J. Neurosci. 26, 3079-3092 (2007).
    • (2007) Eur. J. Neurosci. , vol.26 , pp. 3079-3092
    • Muers, A.1    Clinkers, R.2    Ebinger, G.3    Michotte, Y.4
  • 28
    • 64549104571 scopus 로고    scopus 로고
    • The s-1 receptor interacts with N-alkyl amines and endogenous sphingolipids
    • Ramachandran S, Chu UB, Mavlyutov TA et al. The s-1 receptor interacts with N-alkyl amines and endogenous sphingolipids. Eur. J. Pharmacol. 609, 19-26 (2009).
    • (2009) Eur. J. Pharmacol. , vol.609 , pp. 19-26
    • Ramachandran, S.1    Chu, U.B.2    Mavlyutov, T.A.3
  • 29
    • 0025180755 scopus 로고
    • A s-like binding site in rat pheochromocytoma PC12 cells: Decreased affinity for ±benzomorphans and lower molecular weight suggest a different s receptor form from that of guinea pig brain
    • Hellewell SB, Bowen WD. A s-like binding site in rat pheochromocytoma (PC12) cells: decreased affinity for (+)-benzomorphans and lower molecular weight suggest a different s receptor form from that of guinea pig brain. Brain Res. 527, 244-253 (1990).
    • (1990) Brain Res. , vol.527 , pp. 244-253
    • Hellewell, S.B.1    Bowen, W.D.2
  • 30
    • 0028180570 scopus 로고
    • Rat liver and kidney contain high densities of s1 and s2 receptors: Characterization by ligand binding and photoaffinity labeling
    • Hellewell SB, Bruce A, Feinstein G, Orringer J, Williams W, Bowen WD. Rat liver and kidney contain high densities of s1 and s2 receptors: characterization by ligand binding and photoaffinity labeling. Eur. J. Pharmacol. 268, 9-18 (1994).
    • (1994) Eur. J. Pharmacol. , vol.268 , pp. 9-18
    • Hellewell, S.B.1    Bruce, A.2    Feinstein, G.3    Orringer, J.4    Williams, W.5    Bowen, W.D.6
  • 31
    • 0026332936 scopus 로고
    • Overexpression of s receptors in nonneural human tumors
    • Bem WT, Thomas GE, Mamone JY et al. Overexpression of s receptors in nonneural human tumors. Cancer Res. 51, 6558-6562 (1991).
    • (1991) Cancer Res. , vol.51 , pp. 6558-6562
    • Bem, W.T.1    Thomas, G.E.2    Mamone, J.Y.3
  • 32
    • 0001717594 scopus 로고
    • Characterization of s-like binding sites of NB41A3 S-20Y and N1E-115 neuroblastomas C6 glioma and NG108-15 neuroblastoma-glioma hybrid cells: Further evidence for s-2 receptors
    • 3rd Kamenka, Jean-Marc, Domino, Edward F (Eds) American chemical society, WA, USA
    • Vilner BJ, Bowen WD. Characterization of s-like binding sites of NB41A3, S-20Y, and N1E-115 neuroblastomas, C6 glioma, and NG108-15 neuroblastoma-glioma hybrid cells: further evidence for s-2 receptors. In: Mult. Sigma PCP Recept. Ligands: Mech. Neuromodulation Neuroprot., Proc. Jt. Fr.-U.S. Semin, CNRS-NSF, 3rd. Kamenka, Jean-Marc, Domino, Edward F (Eds). 341-353 American chemical society, WA, USA (1992).
    • (1992) Mult. Sigma PCP Recept Ligands: Mech. Neuromodulation Neuroprot. Proc. Jt. Fr.-U.S. Semin CNRS-NSF , pp. 341-353
    • Vilner, B.J.1    Bowen, W.D.2
  • 33
    • 0031015053 scopus 로고    scopus 로고
    • Wheeler KT s2 receptors as potential biomarkers of proliferation in breast cancer
    • Mach RH, Smith CR, Al-Nabulsi I, Whirrett BR, Childers SR, Wheeler KT. s2 receptors as potential biomarkers of proliferation in breast cancer. Cancer Res. 57, 156-161 (1997).
    • (1997) Cancer Res. , vol.57 , pp. 156-161
    • Mach, R.H.1    Smith, C.R.2    Al-Nabulsi, I.3    Whirrett, B.R.4    Childers, S.R.5
  • 34
    • 58949100861 scopus 로고    scopus 로고
    • New N-substituted 9-azabicyclo3 3 1 nonan-3a-yl phenlcarbamate analogs as s-2 receptor ligands: Synthesis in vitro characterization, and evaluation as PET imaging and chemosensitization agents
    • Chu W, Xu J, Zeng C et al. New N-substituted 9-azabicyclo[3.3.1]nonan-3a- yl phenlcarbamate analogs as s-2 receptor ligands: synthesis, in vitro characterization, and evaluation as PET imaging and chemosensitization agents. Bioorg. Med. Chem. 17, 1222-1231 (2009).
    • (2009) Bioorg. Med. Chem. , vol.17 , pp. 1222-1231
    • Chu, W.1    Xu, J.2    Zeng, C.3
  • 35
    • 33748102817 scopus 로고    scopus 로고
    • Synthesis of N-substituted 9-aza-bucyclo 3 3 1 nonan-3a-yl carbamate analogs as s-2 receptor ligands
    • Vangveravong S, Xu J, Zeng C, Mach RH. Synthesis of N-substituted 9-aza-bucyclo[3.3.1]nonan-3a-yl carbamate analogs as s-2 receptor ligands. Bioorg. Med. Chem. 14, 6988-6997 (2007).
    • (2007) Bioorg. Med. Chem. , vol.14 , pp. 6988-6997
    • Vangveravong, S.1    Xu, J.2    Zeng, C.3    Mach, R.H.4
  • 36
    • 34547773199 scopus 로고    scopus 로고
    • Selective s-2 ligands preferentially bind to pancreatic adenocarcinomas: Application in diagnostic imaging and therapy
    • Kashiwagi H, McDunn JE, Simon PO. Selective s-2 ligands preferentially bind to pancreatic adenocarcinomas: application in diagnostic imaging and therapy. Mol. Cancer 6, 48 (2007).
    • (2007) Mol. Cancer , vol.6 , pp. 48
    • Kashiwagi, H.1    McDunn, J.E.2    Simon, P.O.3
  • 37
    • 65349102411 scopus 로고    scopus 로고
    • S-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma
    • Kashiwagi H, McDunn JE, Simon PO et al. s-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma. J. Transl. Med. 7, 24 (2009).
    • (2009) J. Transl. Med. , vol.7 , pp. 24
    • Kashiwagi, H.1    McDunn, J.E.2    Simon, P.O.3
  • 38
    • 0036141493 scopus 로고    scopus 로고
    • Bowen WD s-2 receptor agonists activate a novel apoptotic pathway and potentiate antineoplastic drugs in breast tumor cell lines
    • Crawford KW, Bowen WD. s-2 receptor agonists activate a novel apoptotic pathway and potentiate antineoplastic drugs in breast tumor cell lines. Cancer Res. 62, 313-322 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 313-322
    • Crawford, K.W.1
  • 39
    • 25444483322 scopus 로고    scopus 로고
    • Effective tumor cell death by s-2 receptor ligand siramesine involves lysosomal leakage and oxidative stress ostenfeld ms fehrenbacher n høyer-hansen m thomsen c farkas t jäättelä M
    • Effective tumor cell death by s-2 receptor ligand siramesine involves lysosomal leakage and oxidative stress. Ostenfeld MS, Fehrenbacher N, Høyer-Hansen M, Thomsen C, Farkas T, Jäättelä M. Cancer Res. 65, 8975-8983 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 8975-8983
  • 40
    • 0037123809 scopus 로고    scopus 로고
    • Bowen WD s2 receptors regulate changes in sphingolipid levels in breast tumor cells
    • Crawford KW, Coop A, Bowen WD. s2 receptors regulate changes in sphingolipid levels in breast tumor cells. Eur. J. Pharmacol. 443, 207-209 (2002).
    • (2002) Eur. J. Pharmacol. , vol.443 , pp. 207-209
    • Crawford, K.W.1    Coop, A.2
  • 41
    • 0028989833 scopus 로고
    • Pang G T s binding site ligands inhibit cell proliferation in mammary and colon carcinoma cell lines and melanoma cells in culture
    • Brent PJ, Pang GT. s binding site ligands inhibit cell proliferation in mammary and colon carcinoma cell lines and melanoma cells in culture. Eur. J. Pharmacol. 278, 151-160 (1995).
    • (1995) Eur. J. Pharmacol. , vol.278 , pp. 151-160
    • Brent, P.J.1
  • 42
    • 0027471841 scopus 로고
    • Bowen WD s receptor-active neuroleptics are cytotoxic to C6 glioma cells in culture
    • Vilner BJ, Bowen WD. s receptor-active neuroleptics are cytotoxic to C6 glioma cells in culture. Eur. J. Pharmacol. 244, 199-201 (1993).
    • (1993) Eur. J. Pharmacol. , vol.244 , pp. 199-201
    • Vilner, B.J.1
  • 43
    • 33748291765 scopus 로고    scopus 로고
    • Cyclohexylpiperazine derivative PB28 a s-2 agonist and s-1 antagonist receptor inhibits cell growth modulates P-glycoprotein and synergizes with anthracyclines in breast cancer
    • Azzariti A, Colabufo NA, Berardi F et al. Cyclohexylpiperazine derivative PB28, a s-2 agonist and s-1 antagonist receptor, inhibits cell growth, modulates P-glycoprotein and synergizes with anthracyclines in breast cancer. Mol. Cancer Ther. 5, 1807-1816 (2006).
    • (2006) Mol. Cancer Ther , vol.5 , pp. 1807-1816
    • Azzariti, A.1    Colabufo, N.A.2    Berardi, F.3
  • 44
    • 0037294002 scopus 로고    scopus 로고
    • 14-Dibenzylpiperazines possess anticocaine activity
    • Foster A, Wu H, Chen W et al. 1,4-Dibenzylpiperazines possess anticocaine activity. Bioorg. Med. Chem. Lett. 13, 749-751 (2003).
    • (2003) Bioorg. Med. Chem. Lett. , vol.13 , pp. 749-751
    • Foster, A.1    Wu, H.2    Chen, W.3
  • 45
    • 0035815645 scopus 로고    scopus 로고
    • -SM 21 attenuates the convulsive and locomotor stimulatory effects of cocaine in mice
    • Matsumoto RR, Mack AL. (+)-SM 21 attenuates the convulsive and locomotor stimulatory effects of cocaine in mice. Eur. J. Pharmacol. 417, R1-R2 (2001).
    • (2001) Eur. J. Pharmacol. , vol.417
    • Matsumoto, R.R.1    Mack, A.L.2
  • 46
    • 0026650831 scopus 로고
    • In vivo electrophysiological evidence for a selective modulation of N-methyl-d-aspartate-induced neuronal activation in rat CA3 dorsal hippocampus by s ligands
    • Monnet FP, Debonnel G, De Montigny C. In vivo electrophysiological evidence for a selective modulation of N-methyl-d-aspartate-induced neuronal activation in rat CA3 dorsal hippocampus by s ligands. J. Pharmacol. Exp. Ther. 261, 123-130 (1992).
    • (1992) J. Pharmacol. Exp. Ther. , vol.261 , pp. 123-130
    • Monnet, F.P.1    Debonnel, G.2    De Montigny, C.3
  • 47
    • 0033529174 scopus 로고    scopus 로고
    • Intracellular s1 receptor modulates phospholipase C and protein kinase C activities in the brainstem
    • USA
    • Morin-Surun MP, Collin T, Denavit-Saubie M, Baulieu EE, Monnet FP. Intracellular s1 receptor modulates phospholipase C and protein kinase C activities in the brainstem. Proc. Natl. Acad. Sci. USA 96, 8196-8199 (1999).
    • (1999) Proc. Natl. Acad. Sci. , vol.96 , pp. 8196-8199
    • Morin-Surun, M.P.1    Collin, T.2    Denavit-Saubie, M.3    Baulieu, E.E.4    Monnet, F.P.5
  • 48
    • 0024427631 scopus 로고
    • Weber E s receptors regulate contractions of the guinea pig ileum longitudinal muscle myenteric plexus preparation elicited by both electrical stimulation and exogenous serotonin
    • Campbell BG, Scherz MW, Keana JF, Weber E. s receptors regulate contractions of the guinea pig ileum longitudinal muscle/ myenteric plexus preparation elicited by both electrical stimulation and exogenous serotonin. J. Neurosci. 9, 3380-3391 (1989).
    • (1989) J. Neurosci. , vol.9 , pp. 3380-3391
    • Campbell, B.G.1    Scherz, M.W.2    Keana, J.F.3
  • 49
    • 0028171131 scopus 로고
    • Regulation of 3H dopamine release from rat striatal slices by s receptor ligands
    • Gonzalez-Alvear GM, Werling LL. Regulation of [3H]dopamine release from rat striatal slices by s receptor ligands. J. Pharmacol. Exp. Ther. 271, 212-219 (1994).
    • (1994) J. Pharmacol. Exp. Ther. , vol.271 , pp. 212-219
    • Gonzalez-Alvear, G.M.1    Werling, L.L.2
  • 50
    • 0030607989 scopus 로고    scopus 로고
    • Regulation of 3H dopamine release from mesolimbic and mesocortical areas of guinea pig brain by sreceptors
    • Weatherspoon JK, Gonzalez-Alvear GM, Frank AR, Werling LL. Regulation of [3H] dopamine release from mesolimbic and mesocortical areas of guinea pig brain by sreceptors. Schizophr. Res. 21, 51-62 (1996).
    • (1996) Schizophr. Res. , vol.21 , pp. 51-62
    • Weatherspoon, J.K.1    Gonzalez-Alvear, G.M.2    Frank, A.R.3    Werling, L.L.4
  • 51
    • 0036779371 scopus 로고    scopus 로고
    • Effect of SA4503 on the electrically evoked release of 3H-acetylcholine from striatal and hippocampal rat brain slices
    • Horan B, Gifford AN, Matsuno K, Mita S, Ashby CR Jr. Effect of SA4503 on the electrically evoked release of 3H-acetylcholine from striatal and hippocampal rat brain slices. Synapse 46, 1-3 (2002).
    • (2002) Synapse , vol.46 , pp. 1-3
    • Horan, B.1    Gifford, A.N.2    Matsuno, K.3    Mita, S.4    Ashby, C.R.Jr.5
  • 52
    • 0025197009 scopus 로고
    • Lipton P s-ligands and non-competitive NMDA antagonists inhibit glutamate release during cerebral ischemia
    • Lobner D, Lipton P. s-ligands and non-competitive NMDA antagonists inhibit glutamate release during cerebral ischemia. Neurosci. Lett. 117, 169-174 (1990).
    • (1990) Neurosci. Lett. , vol.117 , pp. 169-174
    • Lobner, D.1
  • 53
    • 0027853934 scopus 로고
    • Delineating biochemical and functional properties of s receptors: Emerging concepts
    • Su TP. Delineating biochemical and functional properties of s receptors: emerging concepts. Crit. Rev. Neurobiol. 7, 187-203 (1993).
    • (1993) Crit. Rev. Neurobiol. , vol.7 , pp. 187-203
    • Su, T.P.1
  • 56
    • 0036131342 scopus 로고    scopus 로고
    • Effects of s ligands on NMDA receptor function in the bulbectomy model of depression: A behavioural study in the rat
    • Bermack J, Lavoie N, Dryver E, Debonnel G. Effects of s ligands on NMDA receptor function in the bulbectomy model of depression: a behavioural study in the rat. Int. J. Neuropsychopharmacol. 5, 53-62 (2002).
    • (2002) Int. J. Neuropsychopharmacol. , vol.5 , pp. 53-62
    • Bermack, J.1    Lavoie, N.2    Dryver, E.3    Debonnel, G.4
  • 57
    • 0028199907 scopus 로고
    • The effects of s ligands and of neuropeptide Y on N-methyl-d-aspartate- induced neuronal activation of CA3 dorsal hippocampus neurons are differentially affected by pertussis toxin
    • Monnet FP, Debonnel G, Bergeron R, Gronier B, de Montigny C. The effects of s ligands and of neuropeptide Y on N-methyl-d-aspartate-induced neuronal activation of CA3 dorsal hippocampus neurons are differentially affected by pertussis toxin. Br. J. Pharmacol. 112, 709-715 (1994).
    • (1994) Br. J. Pharmacol. , vol.112 , pp. 709-715
    • Monnet, F.P.1    Debonnel, G.2    Bergeron, R.3    Gronier, B.4    De Montigny, C.5
  • 58
    • 0032442582 scopus 로고    scopus 로고
    • E-5842: A new potent and preferential s ligand. Preclinical pharmacological profile
    • Guitart X, Codony X, Ballarin M, Dordal A. Farre AJ. E-5842: a new potent and preferential s ligand. Preclinical pharmacological profile. CNS Drug Rev. 4, 201-224 (1998).
    • (1998) CNS Drug Rev. , vol.4 , pp. 201-224
    • Guitart, X.1    Codony, X.2    Ballarin, M.3    Dordal, A.4    Farre, A.J.5
  • 59
    • 0000476908 scopus 로고
    • NE-100 a novel s receptor ligand: In vivo tests
    • Okuyama S, Imagawa Y, Ogawa S et al. NE-100, a novel s receptor ligand: in vivo tests. Life Sci. 53, PL285-PL290 (1993).
    • (1993) Life Sci. , vol.53
    • Okuyama, S.1    Imagawa, Y.2    Ogawa, S.3
  • 60
    • 0011328699 scopus 로고
    • BMY 14802: A potential antipsychotic agent that selectively binds to s receptors
    • 2nd. Domino, Edward F, Kamenka, Jean-Marc (Eds) American chemical society, WA, USA
    • Taylor DP, Dekleva J. BMY 14802: a potential antipsychotic agent that selectively binds to s receptors. In: Sigma Phencyclidine-like Compd. Mol. Probes Biol., [Proc. U.S.-Fr. Sponsored Int. Semin.], 2nd. Domino, Edward F, Kamenka, Jean-Marc (Eds). American chemical society, WA, USA 345-355 (1988).
    • (1988) Sigma Phencyclidine-like Compd. Mol. Probes Biol. Proc. U.S.-Fr. Sponsored Int. Semin , pp. 345-355
    • Taylor, D.P.1    Dekleva, J.2
  • 61
    • 0028337224 scopus 로고
    • Immunopharmacological profile of SR 31747: In vitro and in vivo studies on humoral and cellular responses
    • Casellas P, Bourrie B, Canat X et al. Immunopharmacological profile of SR 31747: In vitro and in vivo studies on humoral and cellular responses. J. Neuroimmun. 52, 193-203 (1994).
    • (1994) J. Neuroimmun. , vol.52 , pp. 193-203
    • Casellas, P.1    Bourrie, B.2    Canat, X.3
  • 62
    • 0028853342 scopus 로고
    • In vivo inhibition of endotoxin-induced pro-inflammatory cytokines production by the s ligand SR 31747
    • Derocq JM, Bourrie B, Segui M, Le Fur G, Casellas P. In vivo inhibition of endotoxin-induced pro-inflammatory cytokines production by the s ligand SR 31747. J. Pharmacol. Exp. 272, 224-230 (1995).
    • (1995) J. Pharmacol. Exp. , vol.272 , pp. 224-230
    • Derocq, J.M.1    Bourrie, B.2    Segui, M.3    Le Fur, G.4    Casellas, P.5
  • 63
    • 0028818066 scopus 로고
    • Enhancement of endotoxin-induced interleukin-10 production by SR 31747A a s ligand
    • Bourrie B, Bouaboula M, Menoit JM et al. Enhancement of endotoxin-induced interleukin-10 production by SR 31747A, a s ligand. Eur. J. Immun. 25, 2882-2887 (1995).
    • (1995) Eur. J. Immun. , vol.25 , pp. 2882-2887
    • Bourrie, B.1    Bouaboula, M.2    Menoit, J.M.3
  • 64
    • 0030015149 scopus 로고    scopus 로고
    • A s ligand SR 31747A potently modulates staphylococcal enterotoxin B-induced cytokine production in mice
    • Bourrie B, Benoit JM, Derocq JM et al. A s ligand, SR 31747A, potently modulates Staphylococcal enterotoxin B-induced cytokine production in mice. Immunology 88, 389-393 (1996).
    • (1996) Immunology , vol.88 , pp. 389-393
    • Bourrie, B.1    Benoit, J.M.2    Derocq, J.M.3
  • 65
    • 0037027945 scopus 로고    scopus 로고
    • SSR125329A a high affinity s receptor ligand with potent anti-inflammatory properties
    • Bourrie B, Bribes E, De Nys N et al. SSR125329A, a high affinity s receptor ligand with potent anti-inflammatory properties. Eur. J. Pharmacol. 456, 123-131 (2002).
    • (2002) Eur. J. Pharmacol. , vol.456 , pp. 123-131
    • Bourrie, B.1    Bribes, E.2    De Nys, N.3
  • 66
    • 0038054062 scopus 로고    scopus 로고
    • Brackett DJ. s receptors: Potential medications development target for anti-cocaine agents
    • Matsumoto RR, Liu Y, Lerner M, Howard EW, Brackett DJ. s receptors: potential medications development target for anti-cocaine agents. Eur. J. Pharmacol. 469, 1-12 (2003).
    • Eur. J. Pharmacol. , vol.469 , pp. 1-12
    • Matsumoto, R.R.1    Liu, Y.2    Lerner, M.3    Howard, E.W.4
  • 67
    • 0034726011 scopus 로고    scopus 로고
    • Involvement of s 1 receptors in methamphetamine-induced behavioral sensitization in rats
    • Takahashi S, Miwa T, Horikomi K. Involvement of s 1 receptors in methamphetamine-induced behavioral sensitization in rats. Neurosci. Lett. 289, 21-24 (2000).
    • (2000) Neurosci. Lett. , vol.289 , pp. 21-24
    • Takahashi, S.1    Miwa, T.2    Horikomi, K.3
  • 68
    • 0002719634 scopus 로고
    • Structure-activity relationships and evolution of sreceptor ligands 1976-present
    • de Costa BR, He X. Structure-activity relationships and evolution of sreceptor ligands (1976-present). Sigma Recept. 45-111 (1994).
    • (1994) Sigma Recept. , pp. 45-111
    • De Costa, B.R.1    He, X.2
  • 69
    • 77956866269 scopus 로고
    • Glennon RA. s receptors and their ligands: The s enigma
    • Abou-Gharbia M, Ablordeppey SY, Glennon RA. s receptors and their ligands: the s enigma. Annu. Rep. Med. Chem. 28, 1-10 (1993).
    • (1993) Annu. Rep. Med. Chem. , vol.28 , pp. 1-10
    • Abou-Gharbia, M.1    Ablordeppey, S.Y.2
  • 70
    • 0025274410 scopus 로고
    • Metabolites of haloperidol display preferential activity at s receptors compared with dopamine D-2 receptors
    • Bowen WD, Moses EL, Tolentino PJ, Walker JM. Metabolites of haloperidol display preferential activity at s receptors compared with dopamine D-2 receptors. Eur. J. Pharmacol 177, 111-118 (1990).
    • (1990) Eur. J. Pharmacol , vol.177 , pp. 111-118
    • Bowen, W.D.1    Moses, E.L.2    Tolentino, P.J.3    Walker, J.M.4
  • 71
    • 0037059866 scopus 로고    scopus 로고
    • N-arylalkylpiperidines as high-affinity s-1 and s-2 receptor ligands: Phenylpropylamines as potential leads for selective s-2 agents
    • Maeda DY, Williams W, Kim WE, Thatcher LN, Bowen WD, Coop A. N-arylalkylpiperidines as high-affinity s-1 and s-2 receptor ligands: phenylpropylamines as potential leads for selective s-2 agents. Bioorg. Med. Chem. Lett. 12, 497-500 (2002).
    • (2002) Bioorg. Med. Chem. Lett. , vol.12 , pp. 497-500
    • Maeda, D.Y.1    Williams, W.2    Kim, W.E.3    Thatcher, L.N.4    Bowen, W.D.5    Coop, A.6
  • 72
    • 0023514378 scopus 로고
    • Quantitative structure-activity relationships and eudismic analyses of the presynaptic dopaminergic activity and dopamine D2 and s receptor affinities of 3-3-hydroxyphenyl piperidines and octahydrobenz of quinolines
    • Van de Waterbeemd H, El Tayar N, Testa B, Wikstroem H, Largent B. Quantitative structure-activity relationships and eudismic analyses of the presynaptic dopaminergic activity and dopamine D2 and s receptor affinities of 3-(3-hydroxyphenyl)piperidines and octahydrobenzo[f]quinolines. J. Med. Chem. 30, 2175-2181 (1987).
    • (1987) J. Med. Chem. , vol.30 , pp. 2175-2181
    • Van De Waterbeemd, H.1    El Tayar, N.2    Testa, B.3    Wikstroem, H.4    Largent, B.5
  • 73
    • 0034598323 scopus 로고    scopus 로고
    • A s-1 receptor selective analogue of BD1008 A potential substitute for opioids in s receptor binding assays
    • Maeda DY, Williams W, Bowen WD, Coop A. A s-1 receptor selective analogue of BD1008. A potential substitute for (+)-opioids in s receptor binding assays. Bioorg. Med. Chem. Lett. 10, 17-18 (2000).
    • (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 17-18
    • Maeda, D.Y.1    Williams, W.2    Bowen, W.D.3    Coop, A.4
  • 74
    • 0033602524 scopus 로고    scopus 로고
    • Design synthesis structure-activity relationships and biological characterization of novel arylalkoxyphenylalkylamine s ligands as potential antipsychotic drugs
    • Nakazato A, Ohta K, Sekiguchi Y et al. Design, synthesis, structure-activity relationships, and biological characterization of novel arylalkoxyphenylalkylamine s ligands as potential antipsychotic drugs. J. Med. Chem. 42, 1076-1087 (1999).
    • (1999) J. Med. Chem. , vol.42 , pp. 1076-1087
    • Nakazato, A.1    Ohta, K.2    Sekiguchi, Y.3
  • 76
    • 0026452029 scopus 로고
    • Novel piperidine s-receptor ligands as potential antipsychotic drugs
    • Gilligan PJ, Cain GA, Christos TE et al. Novel piperidine s-receptor ligands as potential antipsychotic drugs. J. Med. Chem. 35, 4344-4361 (1992).
    • (1992) J. Med. Chem. , vol.35 , pp. 4344-4361
    • Gilligan, P.J.1    Cain, G.A.2    Christos, T.E.3
  • 78
    • 0025737571 scopus 로고
    • Binding of substituted and conformationally restricted derivatives of N-3-phenyl-N-propyl-1-phenyl-2-aminopropane at s-receptors
    • Glennon RA, Ismaiel AM, Smith JD et al. Binding of substituted and conformationally restricted derivatives of N-(3-phenyl-N-propyl)-1-phenyl-2- aminopropane at s-receptors. J. Med. Chem. 34, 1855-1859 (1991).
    • (1991) J. Med. Chem. , vol.34 , pp. 1855-1859
    • Glennon, R.A.1    Ismaiel, A.M.2    Smith, J.D.3
  • 79
    • 0026319468 scopus 로고
    • S compounds derived from phencyclidine: Identification of PRE-084 a new selective s ligand
    • Su TP, Wu XZ, Cone EJ et al. s compounds derived from phencyclidine: identification of PRE-084, a new, selective s ligand. J. Pharmacol. Exp. Ther. 259, 543-550 (1991).
    • (1991) J. Pharmacol. Exp. Ther. , vol.259 , pp. 543-550
    • Su, T.P.1    Wu, X.Z.2    Cone, E.J.3
  • 81
    • 0024281403 scopus 로고
    • Steroid binding at s receptors suggests a link between endocrine, nervous and immune systems
    • Su TP, London ED, Jaffe JH. Steroid binding at s receptors suggests a link between endocrine, nervous and immune systems. Science 240, 219-221 (1988).
    • (1988) Science , vol.240 , pp. 219-221
    • Su, T.P.1    London, E.D.2    Jaffe, J.H.3
  • 82
    • 0032124437 scopus 로고    scopus 로고
    • A CoMFA investigation of s receptor binding affinity: Reexamination of a spurious s ligand
    • Ablordeppey SY, El-Ashmawy M, Fischer JB, Glennon RA. A CoMFA investigation of s receptor binding affinity: reexamination of a spurious s ligand. Eur. J. Med. Chem. 33, 625-633 (1998).
    • (1998) Eur. J. Med. Chem. , vol.33 , pp. 625-633
    • Ablordeppey, S.Y.1    El-Ashmawy, M.2    Fischer, J.B.3    Glennon, R.A.4
  • 83
    • 23844457000 scopus 로고    scopus 로고
    • Discovery of high-affinity ligands of s-1 receptor ERG2 and emopamil binding protein by pharmacophore modeling and virtual screening
    • Laggner C, Schieferer C, Fiechtner B et al. Discovery of high-affinity ligands of s-1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening. J. Med. Chem. 48, 4754-4764 (2005).
    • (2005) J. Med. Chem. , vol.48 , pp. 4754-4764
    • Laggner, C.1    Schieferer, C.2    Fiechtner, B.3
  • 84
    • 77954346690 scopus 로고    scopus 로고
    • 5D-QSAR for spirocyclic s-1 receptor ligands by quasar receptor surface modeling
    • Oberdorf C, Schmidt TJ, Wünsch B. 5D-QSAR for spirocyclic s-1 receptor ligands by Quasar receptor surface modeling. Eur. J. Med. Chem. 45, 3116-3124 (2010).
    • (2010) Eur. J. Med. Chem. , vol.45 , pp. 3116-3124
    • Oberdorf, C.1    Schmidt, T.J.2    Wünsch, B.3
  • 85
    • 69949100924 scopus 로고    scopus 로고
    • Synthesis biological evaluation and three-dimensional in silico pharmacophore model for s-1 receptor ligands based on a series of substituted benzo d oxazol-2 3H-one derivatives
    • Zamoieri D, Mamolo MG, Laurini E et al. Synthesis, biological evaluation, and three-dimensional in silico pharmacophore model for s-1 receptor ligands based on a series of substituted benzo[d]oxazol-2(3H)-one derivatives. J. Med. Chem. 52, 5380-5393 (2009).
    • (2009) J. Med. Chem. , vol.52 , pp. 5380-5393
    • Zamoieri, D.1    Mamolo, M.G.2    Laurini, E.3
  • 86
    • 0242642846 scopus 로고    scopus 로고
    • Molecular modeling of s-1 receptor ligands: A model of binding conformational and electrostatic considerations
    • Gund TM, Floyd J, Jung D. Molecular modeling of s-1 receptor ligands: a model of binding conformational and electrostatic considerations. J. Mol. Graph. Model 22, 221-230 (2004).
    • (2004) J. Mol. Graph. Model , vol.22 , pp. 221-230
    • Gund, T.M.1    Floyd, J.2    Jung, D.3
  • 87
    • 77950862146 scopus 로고    scopus 로고
    • A 3D-pharmacophore model for s-2 receptors based on a series of substituted benzo d oxazol-2 3H-one derivatives
    • Laurini E, Zampieri D, Mamolo MG et al. A 3D-pharmacophore model for s-2 receptors based on a series of substituted benzo[d] oxazol-2(3H)-one derivatives. Bioorg. Med. Chem. Lett. 20, 2954-2957 (2010).
    • (2010) Bioorg. Med. Chem. Lett. , vol.20 , pp. 2954-2957
    • Laurini, E.1    Zampieri, D.2    Mamolo, M.G.3
  • 88
    • 16644397215 scopus 로고    scopus 로고
    • GRIND-derived pharmacophore model for a series of a-tropanyl derivative ligands of the s-2 receptor
    • Cratteri P, Romanelli MN, Cruciani G, Bonaccini C, Melani F. GRIND-derived pharmacophore model for a series of a-tropanyl derivative ligands of the s-2 receptor. J. Comp. Aid. Mol. Des. 18, 361-374 (2004).
    • (2004) J. Comp. Aid. Mol. Des. , vol.18 , pp. 361-374
    • Cratteri, P.1    Romanelli, M.N.2    Cruciani, G.3    Bonaccini, C.4    Melani, F.5
  • 89
    • 0024385291 scopus 로고
    • Synthesis and evaluation of optically pure 3H-+-pentazocine a highly potent and selective radioligand for s receptors
    • De Costa BR, Bowen WD, Hellewell SB et al. Synthesis and evaluation of optically pure [3H]- (+)-pentazocine, a highly potent and selective radioligand for s receptors. FEBS Lett. 251, 53-58 (1989).
    • (1989) FEBS Lett. , vol.251 , pp. 53-58
    • De Costa, B.R.1    Bowen, W.D.2    Hellewell, S.B.3
  • 90
    • 0011190242 scopus 로고
    • 13-Di 2-5-3H tolyl guanidine: A selective ligand that labels s-type receptors for psychotomimetic opiates and antipsychotic drugs
    • U. S. A.
    • Weber E, Sonders M, Quarum M, McLean S, Pou S, Keana JFW. 1,3-Di(2-[5-3H]tolyl) guanidine: a selective ligand that labels s-type receptors for psychotomimetic opiates and antipsychotic drugs. Proc. Natl. Acad. Sci. U. S. A. 83, 8784-8788 (1986).
    • (1986) Proc. Natl. Acad. Sci , vol.83 , pp. 8784-8788
    • Weber, E.1    Sonders, M.2    Quarum, M.3    McLean, S.4    Pou, S.5    Keana, J.F.W.6
  • 91
    • 0032545520 scopus 로고    scopus 로고
    • The effect of E-5842 a s receptor ligand and potential atypical antipsychotic on Fos expression in rat forebrain
    • Guitart X, Farre AJ. The effect of E-5842, a s receptor ligand and potential atypical antipsychotic, on Fos expression in rat forebrain. Eur. J. Pharmacol. 363, 127-130 (1998).
    • (1998) Eur. J. Pharmacol. , vol.363 , pp. 127-130
    • Guitart, X.1    Farre, A.J.2
  • 92
    • 0032995091 scopus 로고    scopus 로고
    • E-5842: Antipsychotic s-receptor ligand
    • Guitart X, Ballarin M, Codony X et al. E-5842: antipsychotic s-receptor ligand. Drugs Future 24, 386-392 (1999).
    • (1999) Drugs Future , vol.24 , pp. 386-392
    • Guitart, X.1    Ballarin, M.2    Codony, X.3
  • 93
    • 0032543727 scopus 로고    scopus 로고
    • Synthesis and quantitative structure-activity relationships of N-1-benzylpiperidin-4-yl phenylacetamides and related analogs as potent and selective s1 receptor ligands
    • Huang Y, Hammond PS, Whirrett BR et al. Synthesis and quantitative structure-activity relationships of N-(1-benzylpiperidin-4-yl) phenylacetamides and related analogs as potent and selective s1 receptor ligands. J. Med. Chem. 41, 2361-2370 (1998).
    • (1998) J. Med. Chem. , vol.41 , pp. 2361-2370
    • Huang, Y.1    Hammond, P.S.2    Whirrett, B.R.3
  • 94
    • 0028049301 scopus 로고
    • NE-100 a novel potent s ligand preferentially binds to s1 binding sites in guinea pig brain
    • Chaki S, Tanaka M, Muramatsu M, Otomo S. NE-100, a novel potent s ligand, preferentially binds to s1 binding sites in guinea pig brain. Eur. J. Pharmacol. 251, R1-R2 (1994).
    • (1994) Eur. J. Pharmacol. , vol.251
    • Chaki, S.1    Tanaka, M.2    Muramatsu, M.3    Otomo, S.4
  • 95
    • 0032492927 scopus 로고    scopus 로고
    • 1-benzyl-3 4-dihydrospiro 2H-1- benzothiopyran-2 4́-piperidine spipethiane a potent and highly selective s1 ligand
    • Quaglia W, Giannella M, Piergentili A et al. 1-benzyl-3,4- dihydrospiro[2H-1- benzothiopyran-2,4́-piperidine] (spipethiane), a potent and highly selective s1 ligand. J. Med. Chem. 41, 1557-1560 (1998).
    • (1998) J. Med. Chem. , vol.41 , pp. 1557-1560
    • Quaglia, W.1    Giannella, M.2    Piergentili, A.3
  • 96
    • 0037168069 scopus 로고    scopus 로고
    • Novel s receptor ligands part 2 SAR of Spiro 2 benzopyran- 1 4́-piperid- ines and spiro enzofuran-1 4́-piperidines with carbon substituents in position 3
    • Maier CA, Wünsch B. Novel s receptor ligands. Part 2. SAR of Spiro[[2]benzopyran- 1,4́-piperid- ines] and spiro[[2]benzofuran- 1,4́-piperidines] with carbon substituents in position 3. J. Med. Chem. 43, 4923-4930 (2002).
    • (2002) J. Med. Chem. , vol.43 , pp. 4923-4930
    • Maier, C.A.1    Wünsch, B.2
  • 97
    • 77953130623 scopus 로고    scopus 로고
    • Synthesis and characterization of N N-dialkyl and N-alkyl-N-aralkyl fenpropimorph-derived compounds as high affinity ligands for s receptors
    • Hajipour AR, Fontanilla D, Chu UB, Arbabian M, Ruoho AE. Synthesis and characterization of N,N-dialkyl and N-alkyl-N-aralkyl fenpropimorph-derived compounds as high affinity ligands for s receptors. Bioorg. Med. Chem. 18, 4397-4404 (2010).
    • (2010) Bioorg. Med. Chem. , vol.18 , pp. 4397-4404
    • Hajipour, A.R.1    Fontanilla, D.2    Chu, U.B.3    Arbabian, M.4    Ruoho, A.E.5
  • 99
    • 0029068247 scopus 로고
    • CB-64D and CB-184: Ligands with high s-2 receptor affinity and subtype selectivity
    • Bowen WD, Bertha CM, Vilner BJ, Rice KC. CB-64D and CB-184: ligands with high s-2 receptor affinity and subtype selectivity. Eur. J. Pharmacol. 278, 257-260 (1995).
    • (1995) Eur. J. Pharmacol. , vol.278 , pp. 257-260
    • Bowen, W.D.1    Bertha, C.M.2    Vilner, B.J.3    Rice, K.C.4
  • 100
    • 0034053453 scopus 로고    scopus 로고
    • Modulation of cellular calcium by s-2 receptors: Release from intracellular stores in human SK-N-SH neuroblastoma cells
    • Vilner BJ, Bowen WD. Modulation of cellular calcium by s-2 receptors: release from intracellular stores in human SK-N-SH neuroblastoma cells. J. Pharmacol. Exp. Ther. 292, 900-911 (2000).
    • (2000) J. Pharmacol. Exp. Ther. , vol.292 , pp. 900-911
    • Vilner, B.J.1    Bowen, W.D.2
  • 102
    • 0035233409 scopus 로고    scopus 로고
    • S receptors and iboga alkaloids
    • Bowen WD. s receptors and iboga alkaloids. Alkaloids Chem. Biol. 56, 173-191 (2001).
    • (2001) Alkaloids Chem. Biol. , vol.56 , pp. 173-191
    • Bowen, W.D.1
  • 103
    • 0029062721 scopus 로고
    • S ligands with subnanomolar affinity and preference for the s2 binding site 2 Spiro-joined benzofuran isobenzofuran and benzopyran piperidines
    • Moltzen EK, Perregaard J, Meier E. s ligands with subnanomolar affinity and preference for the s2 binding site. 2. Spiro-joined benzofuran, isobenzofuran, and benzopyran piperidines. J. Med. Chem. 38, 2009-2017 (1995).
    • (1995) J. Med. Chem. , vol.38 , pp. 2009-2017
    • Moltzen, E.K.1    Perregaard, J.2    Meier, E.3
  • 104
    • 0037765110 scopus 로고    scopus 로고
    • Synthesis of N-substituted 9-azabicyclo 3.3.1 nonan-3a-yl phenylcarbamate analogs as s-2 receptor ligands
    • Mach RH, Vangveravong S, Huang Y, Yang B, Blair JB, Wu L. Synthesis of N-substituted 9-azabicyclo[3.3.1]nonan-3a-yl phenylcarbamate analogs as s-2 receptor ligands. Med. Chem. Res. 11, 380-398 (2002).
    • (2002) Med. Chem. Res. , vol.11 , pp. 380-398
    • Mach, R.H.1    Vangveravong, S.2    Huang, Y.3    Yang, B.4    Blair, J.B.5    Wu, L.6
  • 105
    • 0001524144 scopus 로고    scopus 로고
    • The analgesic tropane analog ±-SM 21 has a high affinity for s2 receptors
    • Mach RH, Wu L, West T, Whirrett BR, Childers SR. The analgesic tropane analog (±)-SM 21 has a high affinity for s2 receptors. Life Sci. 64, PL131-PL137 (1999).
    • (1999) Life Sci. , vol.64
    • Mach, R.H.1    Wu, L.2    West, T.3    Whirrett, B.R.4    Childers, S.R.5
  • 106
    • 0029065278 scopus 로고
    • S ligands with subnanomolar affinity and preference for the s2 binding site 1 3-w-aminoalkyl-1h-indoles
    • Perregaard J, Moltzen EK, Meier E, Sanchez C. s ligands with subnanomolar affinity and preference for the s2 binding site. 1. 3-(w-aminoalkyl)-1h- indoles. J. Med. Chem. 38, 1998-2008 (1995).
    • (1995) J. Med. Chem. , vol.38 , pp. 1998-2008
    • Perregaard, J.1    Moltzen, E.K.2    Meier, E.3    Sanchez, C.4
  • 108
    • 1842679213 scopus 로고    scopus 로고
    • 4-tetralin-1-yl- and 4-naphthalen-1-yl alkyl derivatives of 1-cyclohexylpiperazine as s receptor ligands with agonist s2 activity
    • Berardi F, Ferorelli S, Abate C et al. 4-(tetralin-1-yl)- and 4-(naphthalen-1-yl) alkyl derivatives of 1-cyclohexylpiperazine as s receptor ligands with agonist s2 activity. J. Med. Chem. 47, 2308-2317 (2004).
    • (2004) J. Med. Chem. , vol.47 , pp. 2308-2317
    • Berardi, F.1    Ferorelli, S.2    Abate, C.3
  • 109
    • 0033625546 scopus 로고    scopus 로고
    • In vivo evaluation of 11C SA4503 as a PET ligand for mapping CNS s-1 receptors
    • Kawamura K, Ishiwata K, Tajima H et al. In vivo evaluation of [11C]SA4503 as a PET ligand for mapping CNS s-1 receptors. Nucl. Med. Biol. 27(3), 255-261 (2000).
    • (2000) Nucl. Med. Biol. , vol.27 , Issue.3 , pp. 255-261
    • Kawamura, K.1    Ishiwata, K.2    Tajima, H.3
  • 110
    • 0035371973 scopus 로고    scopus 로고
    • Mapping of CNS s1 receptors in the conscious monkey: Preliminary PET study with 11C SA4503
    • Ishiwata K, Tsukada H, Kawamura K et al. Mapping of CNS s1 receptors in the conscious monkey: preliminary PET study with [11C]SA4503. Synapse 40, 235-237 (2001).
    • (2001) Synapse , vol.40 , pp. 235-237
    • Ishiwata, K.1    Tsukada, H.2    Kawamura, K.3
  • 111
    • 0042886040 scopus 로고    scopus 로고
    • An increase in s1 receptors in aged monkey brain
    • Kawamura K, Kimura Y, Tsukada H et al. An increase in s1 receptors in aged monkey brain. Neurobiol. Ageing 24, 745-752 (2003).
    • (2003) Neurobiol. Ageing , vol.24 , pp. 745-752
    • Kawamura, K.1    Kimura, Y.2    Tsukada, H.3
  • 112
    • 34748820517 scopus 로고    scopus 로고
    • High occupancy of s-1 receptors in human brain after single oral administration of fluvoxamine: A positron emission tomography study using 11C SA4503
    • Ishikawa M, Ishiwata K, Ishii K et al. High occupancy of s-1 receptors in human brain after single oral administration of fluvoxamine: a positron emission tomography study using [11C]SA4503. Biol. Psychiatry. 62(8), 878-883 (2007).
    • (2007) Biol. Psychiatry , vol.62 , Issue.8 , pp. 878-883
    • Ishikawa, M.1    Ishiwata, K.2    Ishii, K.3
  • 113
    • 0030610886 scopus 로고    scopus 로고
    • In vivo evaluation of 18F 1-3-fluoropropyl-4-4- cyanophenoxymethyl piperidine: A selective s-1 receptor radioligand for PET
    • Waterhouse RN, Collier TL. In vivo evaluation of [18F]1-(3-fluoropropyl)- 4-(4- cyanophenoxymethyl)piperidine: a selective s-1 receptor radioligand for PET. Nucl. Med. Biol. 24, 127-134 (1997).
    • (1997) Nucl. Med. Biol. , vol.24 , pp. 127-134
    • Waterhouse, R.N.1    Collier, T.L.2
  • 114
    • 0037805586 scopus 로고    scopus 로고
    • Preclinical acute toxicity studies and rodent-based dosimetry estimates of the novel s-1 receptor radiotracer 18F FPS
    • Waterhouse RN, Stabin MG, Page JG. Preclinical acute toxicity studies and rodent-based dosimetry estimates of the novel s-1 receptor radiotracer [18F]FPS. Nucl. Med. Biol. 30, 555-563 (2003).
    • (2003) Nucl. Med. Biol. , vol.30 , pp. 555-563
    • Waterhouse, R.N.1    Stabin, M.G.2    Page, J.G.3
  • 115
    • 34250790845 scopus 로고    scopus 로고
    • Synthesis and evaluation of fluorine-18- labeled SA4503 as a selective s1 receptor ligand for positron emission tomography
    • Kawamura K, Tsukada H, Shiba K et al. Synthesis and evaluation of fluorine-18- labeled SA4503 as a selective s1 receptor ligand for positron emission tomography. Nucl. Med. Biol. 34, 571-577 (2007).
    • (2007) Nucl. Med. Biol. , vol.34 , pp. 571-577
    • Kawamura, K.1    Tsukada, H.2    Shiba, K.3
  • 116
    • 70349651658 scopus 로고    scopus 로고
    • Evaluation of spirocyclic 3-3-fluoropropyl- 2-benzofuran as s 1 receptor ligands for neuroimaging with positron imaging tomography
    • Maestrup EG, Fischer S, Wiese C et al. Evaluation of spirocyclic 3-(3-fluoropropyl)- 2-benzofuran as s 1 receptor ligands for neuroimaging with positron imaging tomography. J. Med. Chem. 52, 6062-6072 (2009).
    • (2009) J. Med. Chem. , vol.52 , pp. 6062-6072
    • Maestrup, E.G.1    Fischer, S.2    Wiese, C.3
  • 117
    • 28044445696 scopus 로고    scopus 로고
    • 3H N-4-3 4- dihydro-6 7-dimethoxyisoquinolin-2 1H-yl butyl -2-methoxy-5-methylbenzamide: A novel s-2 receptor probe
    • Xu J, Ti Z, Jones LA, Vangveravong S, Wheeler KT, Mach RH. [3H]N-[4-(3,4- dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl) butyl]-2-methoxy-5-methylbenzamide: a novel s-2 receptor probe. Eur. J. Pharmacol. 525, 8-17 (2005).
    • (2005) Eur. J. Pharmacol. , vol.525 , pp. 8-17
    • Xu, J.1    Ti, Z.2    Jones, L.A.3    Vangveravong, S.4    Wheeler, K.T.5    Mach, R.H.6
  • 118
    • 40749123571 scopus 로고    scopus 로고
    • Tritium radiolabelling of PB28 a potent s2 receptor ligand: Pharmacokinetic and pharmacodynamic characterization
    • Colabufo NA, Abate C, Contino M et al. Tritium radiolabelling of PB28, a potent s2 receptor ligand: pharmacokinetic and pharmacodynamic characterization. Bioorg. Med. Chem. Lett. 18, 2183-2187 (2008).
    • (2008) Bioorg. Med. Chem. Lett. , vol.18 , pp. 2183-2187
    • Colabufo, N.A.1    Abate, C.2    Contino, M.3
  • 119
    • 33746093953 scopus 로고    scopus 로고
    • Synthesis and in vivo evaluation of 2 high-affinity 76Br-labeled s-2- receptor ligands
    • Rowland DJ, Tu Z, Xu J et al. Synthesis and in vivo evaluation of 2 high-affinity 76Br-labeled s-2- receptor ligands. J. Nucl. Med. 47(6), 1041-1048 (2006).
    • (2006) J. Nucl. Med. , vol.47 , Issue.6 , pp. 1041-1048
    • Rowland, D.J.1    Tu, Z.2    Xu, J.3
  • 120
    • 34447511371 scopus 로고    scopus 로고
    • Fluorine-18-labeled benzamide analogues for imaging the s2 receptor status of solid tumor with positron emission tomography
    • Tu Z, Jones LA, Li S et al. Fluorine-18-labeled benzamide analogues for imaging the s2 receptor status of solid tumor with positron emission tomography. J. Med. Chem. 50(14), 3194-3204 (2007).
    • (2007) J. Med. Chem. , vol.50 , Issue.14 , pp. 3194-3204
    • Tu, Z.1    Jones, L.A.2    Li, S.3
  • 121
    • 77956408380 scopus 로고    scopus 로고
    • Radiosynthesis and biological evaluation of a promising s2 receptor ligand radiolabeled with fluorine-18 or iodine-125 as a PET SPECT probe for imaging breast cancer
    • Tu Z, Xu J, Jones LA et al.Radiosynthesis and biological evaluation of a promising s2 receptor ligand radiolabeled with fluorine-18 or iodine-125 as a PET/SPECT probe for imaging breast cancer. Appl. Radiat. Isot. 68, 2268-2273 (2010).
    • (2010) Appl. Radiat. Isot. , vol.68 , pp. 2268-2273
    • Tu, Z.1    Xu, J.2    Jones, L.A.3


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