1'-benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4'-piperidine] (Spipethiane), a potent and highly selective σ1 ligand

Journal of Medicinal Chemistry

Volumn 41, Issue 10, 1998, Pages 1557-1560

  Quaglia, Wilma ^a   Giannella, Mario ^a   Piergentili, Alessandro ^a   Pigini, Maria ^a   Brasili, Livio ^b   Toro, Rosanna ^c   Rossetti, Lorena ^c   Spampinato, Santi ^c   Melchiorre, Carlo ^c  

^a UNIVERSITY OF CAMERINO   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PIPERIDINE DERIVATIVE; SPIPETHIANE; UNCLASSIFIED DRUG;

DRUG ACTIVITY; DRUG BINDING; DRUG POTENCY; DRUG STRUCTURE; LETTER; LIGAND BINDING;

ANIMALS; GUINEA PIGS; LIGANDS; PIPERIDINES; RATS; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, DOPAMINE D2; RECEPTORS, MUSCARINIC; RECEPTORS, OPIOID; RECEPTORS, SEROTONIN; RECEPTORS, SIGMA; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032492927     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970740r     Document Type: Letter

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