Synthesis and characterization of N,N-dialkyl and N-alkyl-N-aralkyl fenpropimorph-derived compounds as high affinity ligands for sigma receptors

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 12, 2010, Pages 4397-4404

  Hajipour, Abdol R ^a,b   Fontanilla, Dominique ^a   Chu, Uyen B ^a   Arbabian, Marty ^a   Ruoho, Arnold E ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b ISFAHAN UNIVERSITY OF TECHNOLOGY   (Iran)

Author keywords

Cancer; Fenpropimorphy; Sigma receptor; Tumor cell lines

Indexed keywords

FENPROPIMORPH; LIGAND; N PROPYL N' 4 AMINOPHENYLETHYL 3 (4 NITROPHENYL)PROPYLAMINE; N,N DIBUTYL 3 (4 FLUOROPHENYL)PROPYLAMINE; N,N DIBUTYL 3 (4 NITROPHENYL)PROPYLAMINE; PROPYLAMINE; SIGMA 1 OPIATE RECEPTOR; UNCLASSIFIED DRUG; ANILINE DERIVATIVE; ANTINEOPLASTIC AGENT; MORPHOLINE DERIVATIVE; N,N-DIBUTYL-3-(4-FLUOROPHENYL)PROPYLAMINE; N,N-DIBUTYL-3-(4-NITROPHENYL)PROPYLAMINE; N-PROPYL-N'-4-AMINOPHENYLETHYL-3-(4-NITROPHENYL)PROPYLAMINE; PROTEIN BINDING; SIGMA OPIATE RECEPTOR; SIGMA-1 RECEPTOR;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; GROWTH INHIBITION; HUMAN; HUMAN CELL; PHARMACOPHORE; RECEPTOR AFFINITY; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG SCREENING; METABOLISM; SYNTHESIS; TOXICITY; TUMOR CELL LINE;

ANILINE COMPOUNDS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LIGANDS; MORPHOLINES; PROPYLAMINES; PROTEIN BINDING; RECEPTORS, SIGMA;

EID: 77953130623     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.04.078     Document Type: Article

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