메뉴 건너뛰기




Volumn 7, Issue 4, 2010, Pages 301-310

Traumatic spinal cord injury alters angiogenic factors and TGF-betal that may affect vascular recovery

Author keywords

Angiogenic factors; Gene expression; Rat model; Revascularization; Spinal cord injury; Vessel regression

Indexed keywords

ANGIOGENIC FACTOR; ANGIOPOIETIN 1; CYSTEINE RICH PROTEIN 61; MESSENGER RNA; PLACENTAL GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN;

EID: 78650632991     PISSN: 15672026     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720210793180756     Document Type: Article
Times cited : (31)

References (84)
  • 1
    • 38149090292 scopus 로고    scopus 로고
    • The blood-brain barrier in health and chronic neurodegenerative disorders
    • Zlokovic BV. The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 2008; 57(2): 178-201.
    • (2008) Neuron , vol.57 , Issue.2 , pp. 178-201
    • Zlokovic, B.V.1
  • 3
    • 0031128370 scopus 로고    scopus 로고
    • Spinal cord compression injury in guinea pigs: Structural changes of endothelium and its perivascular cell associations after blood-brain barrier breakdown and repair
    • Jaeger CB, Blight AR. Spinal cord compression injury in guinea pigs: structural changes of endothelium and its perivascular cell associations after blood-brain barrier breakdown and repair. Exp Neurol 1997; 144(2): 381-99.
    • (1997) Exp Neurol , vol.144 , Issue.2 , pp. 381-399
    • Jaeger, C.B.1    Blight, A.R.2
  • 4
    • 0030875191 scopus 로고    scopus 로고
    • Local changes in vascular architecture following partial spinal cord lesion in the rat
    • Imperato-Kalmar EL, McKinney RA, Schnell L, Rubin BP, Schwab ME. Local changes in vascular architecture following partial spinal cord lesion in the rat. Exp Neurol 1997; 145(2 Pt 1): 322-8.
    • (1997) Exp Neurol , vol.145 , Issue.2 PART 1 , pp. 322-328
    • Imperato-Kalmar, E.L.1    McKinney, R.A.2    Schnell, L.3    Rubin, B.P.4    Schwab, M.E.5
  • 5
    • 0036144964 scopus 로고    scopus 로고
    • New vascular tissue rapidly replaces neural parenchyma and vessels destroyed by a contusion injury to the rat spinal cord
    • Casella GT, Marcillo A, Bunge MB, Wood PM. New vascular tissue rapidly replaces neural parenchyma and vessels destroyed by a contusion injury to the rat spinal cord. Exp Neurol 2002; 173(1): 63-76.
    • (2002) Exp Neurol , vol.173 , Issue.1 , pp. 63-76
    • Casella, G.T.1    Marcillo, A.2    Bunge, M.B.3    Wood, P.M.4
  • 6
    • 0037089824 scopus 로고    scopus 로고
    • Temporal progression of angiogenesis and basal lamina deposition after contusive spinal cord injury in the adult rat
    • Loy DN, Crawford CH, Darnall JB, Burke DA, Onifer SM, Whittemore SR. Temporal progression of angiogenesis and basal lamina deposition after contusive spinal cord injury in the adult rat. J Comp Neurol 2002; 445(4): 308-24.
    • (2002) J Comp Neurol , vol.445 , Issue.4 , pp. 308-324
    • Loy, D.N.1    Crawford, C.H.2    Darnall, J.B.3    Burke, D.A.4    Onifer, S.M.5    Whittemore, SR.6
  • 7
    • 0026326449 scopus 로고
    • Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms
    • Tator CH, Fehlings MG. Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms. J Neurosurg 1991; 75(1): 15-26.
    • (1991) J Neurosurg , vol.75 , Issue.1 , pp. 15-26
    • Tator, C.H.1    Fehlings, M.G.2
  • 8
    • 77951701586 scopus 로고    scopus 로고
    • CD133 expressing pericytes and relationship to SDF-1 and CXCR4 in spinal cord injury
    • Graumann U, Ritz MF, Rivero BG, Hausmann O. CD133 expressing pericytes and relationship to SDF-1 and CXCR4 in spinal cord injury. Curr Neurovasc Res 2010; 7(2): 144-54.
    • (2010) Curr Neurovasc Res , vol.7 , Issue.2 , pp. 144-154
    • Graumann, U.1    Ritz, M.F.2    Rivero, B.G.3    Hausmann, O.4
  • 9
    • 0038376002 scopus 로고    scopus 로고
    • Molecular regulation of vessel maturation
    • Jain RK. Molecular regulation of vessel maturation. Nat Med 2003; 9(6): 685-93.
    • (2003) Nat Med , vol.9 , Issue.6 , pp. 685-693
    • Jain, R.K.1
  • 10
    • 2442689337 scopus 로고    scopus 로고
    • Adenosine A(2A) receptor activation promotes wound neovascularization by stimulating angiogenesis and vasculogenesis
    • Montesinos MC, Shaw JP, Yee H, Shamamian P, Cronstein BN. Adenosine A(2A) receptor activation promotes wound neovascularization by stimulating angiogenesis and vasculogenesis. Am J Pathol 2004; 164(6): 1887-92.
    • (2004) Am J Pathol , vol.164 , Issue.6 , pp. 1887-1892
    • Montesinos, M.C.1    Shaw, J.P.2    Yee, H.3    Shamamian, P.4    Cronstein, B.N.5
  • 12
    • 0031900714 scopus 로고    scopus 로고
    • Differentiation of blood-brain barrier endothelial cells
    • Risau W, Esser S, Engelhardt B. Differentiation of blood-brain barrier endothelial cells. Pathol Biol (Paris) 1998; 46(3): 171-5.
    • (1998) Pathol Biol (Paris) , vol.46 , Issue.3 , pp. 171-175
    • Risau, W.1    Esser, S.2    Engelhardt, B.3
  • 13
    • 0032125525 scopus 로고    scopus 로고
    • Spontaneous longitudinally orientated axonal regeneration is associated with the Schwann cell framework within the lesion site following spinal cord compression injury of the rat
    • Brook GA, Plate D, Franzen R, et al. Spontaneous longitudinally orientated axonal regeneration is associated with the Schwann cell framework within the lesion site following spinal cord compression injury of the rat. J Neurosci Res 1998; 53(1): 51-65.
    • (1998) J Neurosci Res , vol.53 , Issue.1 , pp. 51-65
    • Brook, G.A.1    Plate, D.2    Franzen, R.3
  • 14
    • 34547650849 scopus 로고    scopus 로고
    • Spinal cord injury-induced expression of the antiangiogenic endostatin/collagen XVIII in areas of vascular remodelling
    • Mueller CA, Conrad S, Schluesener HJ, Pietsch T, Schwab JM. Spinal cord injury-induced expression of the antiangiogenic endostatin/collagen XVIII in areas of vascular remodelling. J Neurosurg Spine 2007; 7(2): 205-14.
    • (2007) J Neurosurg Spine , vol.7 , Issue.2 , pp. 205-214
    • Mueller, C.A.1    Conrad, S.2    Schluesener, H.J.3    Pietsch, T.4    Schwab, J.M.5
  • 15
    • 34547633098 scopus 로고    scopus 로고
    • Hepatocyte growth factor promotes endogenous repair and functional recovery after spinal cord injury
    • Kitamura K, Iwanami A, Nakamura M, et al. Hepatocyte growth factor promotes endogenous repair and functional recovery after spinal cord injury. J Neurosci Res 2007; 85(11): 2332-42.
    • (2007) J Neurosci Res , vol.85 , Issue.11 , pp. 2332-2342
    • Kitamura, K.1    Iwanami, A.2    Nakamura, M.3
  • 16
    • 0042133340 scopus 로고    scopus 로고
    • Vascular endothelial growth factor improves functional outcome and decreases secondary degeneration in experimental spinal cord contusion injury
    • Widenfalk J, Lipson A, Jubran M, et al. Vascular endothelial growth factor improves functional outcome and decreases secondary degeneration in experimental spinal cord contusion injury. Neuroscience 2003; 120(4): 951-60.
    • (2003) Neuroscience , vol.120 , Issue.4 , pp. 951-960
    • Widenfalk, J.1    Lipson, A.2    Jubran, M.3
  • 17
    • 69249108768 scopus 로고    scopus 로고
    • Reduced Vascular Endothelial Growth Factor Expression in Contusive Spinal Cord Injury
    • Herrera JJ, Nesic-Taylor DO, Narayana PA. Reduced Vascular Endothelial Growth Factor Expression In Contusive Spinal Cord Injury. J Neurotrauma 2009; 26: 995-1003.
    • (2009) J Neurotrauma , vol.26 , pp. 995-1003
    • Herrera, J.J.1    Nesic-Taylor, D.O.2    Narayana, P.A.3
  • 18
    • 0037314660 scopus 로고    scopus 로고
    • Lesional expression of a proinflammatory and antiangiogenic cytokine EMAP II confined to endothelium and microglia/ macrophages during secondary damage following experimental traumatic brain injury
    • Mueller CA, Schluesener HJ, Conrad S, Meyermann R, Schwab JM. Lesional expression of a proinflammatory and antiangiogenic cytokine EMAP II confined to endothelium and microglia/ macrophages during secondary damage following experimental traumatic brain injury. J Neuroimmunol 2003; 135(12): 1-9.
    • (2003) J Neuroimmunol , vol.135 , Issue.1-2 , pp. 1-9
    • Mueller, C.A.1    Schluesener, H.J.2    Conrad, S.3    Meyermann, R.4    Schwab, J.M.5
  • 19
    • 0036445830 scopus 로고    scopus 로고
    • Vascular and neuronal effects of VEGF in the nervous system: Implications for neurological disorders
    • Carmeliet P, Storkebaum E. Vascular and neuronal effects of VEGF in the nervous system: implications for neurological disorders. Semin Cell Dev Biol 2002; 13(1): 39-53.
    • (2002) Semin Cell Dev Biol , vol.13 , Issue.1 , pp. 39-53
    • Carmeliet, P.1    Storkebaum, E.2
  • 20
    • 17344390961 scopus 로고    scopus 로고
    • Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor
    • Pettersson A, Nagy JA, Brown LF, et al. Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor. Lab Invest 2000; 80(1): 99-115.
    • (2000) Lab Invest , vol.80 , Issue.1 , pp. 99-115
    • Pettersson, A.1    Nagy, J.A.2    Brown, L.F.3
  • 21
    • 0030460424 scopus 로고    scopus 로고
    • Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning
    • Davis S, Aldrich TH, Jones PF, et al. Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell 1996; 87(7): 1161-9.
    • (1996) Cell , vol.87 , Issue.7 , pp. 1161-1169
    • Davis, S.1    Aldrich, T.H.2    Jones, P.F.3
  • 24
    • 34547637867 scopus 로고    scopus 로고
    • Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102
    • Sennino B, Falcon BL, McCauley D, et al. Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102. Cancer Res 2007; 67(15): 7358-67.
    • (2007) Cancer Res , vol.67 , Issue.15 , pp. 7358-7367
    • Sennino, B.1    Falcon, B.L.2    McCauley, D.3
  • 25
    • 5444260754 scopus 로고    scopus 로고
    • Vascular frontiers without borders: Multifaceted roles of platelet-derived growth factor (PDGF) in supporting postnatal angiogenesis and lymphangiogenesis
    • Vincent L, Rafii S. Vascular frontiers without borders: multifaceted roles of platelet-derived growth factor (PDGF) in supporting postnatal angiogenesis and lymphangiogenesis. Cancer Cell 2004; 6(4): 307-9.
    • (2004) Cancer Cell , vol.6 , Issue.4 , pp. 307-309
    • Vincent, L.1    Rafii, S.2
  • 26
    • 33847379437 scopus 로고    scopus 로고
    • G-CSF and HGF: Combination of vasculogenesis and angiogenesis synergistically improves recovery in murine hind limb ischemia
    • Ieda Y, Fujita J, Ieda M, et al. G-CSF and HGF: combination of vasculogenesis and angiogenesis synergistically improves recovery in murine hind limb ischemia. J Mol Cell Cardiol 2007; 42(3): 540-8.
    • (2007) J Mol Cell Cardiol , vol.42 , Issue.3 , pp. 540-548
    • Ieda, Y.1    Fujita, J.2    Ieda, M.3
  • 27
    • 0035996581 scopus 로고    scopus 로고
    • Hepatocyte growth factor is a survival factor for endothelial cells and is expressed in human atherosclerotic plaques
    • Ma H, Calderon TM, Fallon JT, Berman JW. Hepatocyte growth factor is a survival factor for endothelial cells and is expressed in human atherosclerotic plaques. Atherosclerosis 2002; 164(1): 79-87.
    • (2002) Atherosclerosis , vol.164 , Issue.1 , pp. 79-87
    • Ma, H.1    Calderon, T.M.2    Fallon, J.T.3    Berman, J.W.4
  • 28
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • Carmeliet P. Angiogenesis in health and disease. Nat Med 2003; 9(6): 653-60.
    • (2003) Nat Med , vol.9 , Issue.6 , pp. 653-660
    • Carmeliet, P.1
  • 29
    • 34547937556 scopus 로고    scopus 로고
    • The angiogenic factor CCN1 promotes adhesion and migration of circulating CD34+ progenitor cells: Potential role in angiogenesis and endothelial regeneration
    • Grote K, Salguero G, Ballmaier M, Dangers M, Drexler H, Schieffer B. The angiogenic factor CCN1 promotes adhesion and migration of circulating CD34+ progenitor cells: potential role in angiogenesis and endothelial regeneration. Blood 2007; 110(3): 877-85.
    • (2007) Blood , vol.110 , Issue.3 , pp. 877-885
    • Grote, K.1    Salguero, G.2    Ballmaier, M.3    Dangers, M.4    Drexler, H.5    Schieffer, B.6
  • 30
    • 41549100146 scopus 로고    scopus 로고
    • Cysteine-rich protein 61 and connective tissue growth factor induce deadhesion and anoikis of retinal pericytes
    • Liu H, Yang R, Tinner B, Choudhry A, Schutze N, Chaqour B. Cysteine-rich protein 61 and connective tissue growth factor induce deadhesion and anoikis of retinal pericytes. Endocrinology 2008; 149(4): 1666-77.
    • (2008) Endocrinology , vol.149 , Issue.4 , pp. 1666-1677
    • Liu, H.1    Yang, R.2    Tinner, B.3    Choudhry, A.4    Schutze, N.5    Chaqour, B.6
  • 31
    • 0142116387 scopus 로고    scopus 로고
    • VEGF165 therapy exacerbates secondary damage following spinal cord injury
    • Benton RL, Whittemore SR. VEGF165 therapy exacerbates secondary damage following spinal cord injury. Neurochem Res 2003; 28(11): 1693-703.
    • (2003) Neurochem Res , vol.28 , Issue.11 , pp. 1693-1703
    • Benton, R.L.1    Whittemore, SR.2
  • 32
    • 27544451238 scopus 로고    scopus 로고
    • VEGF-induced BBB permeability is associated with an MMP-9 activity increase in cerebral ischemia: Both effects decreased by Ang-1
    • Valable S, Montaner J, Bellail A, et al. VEGF-induced BBB permeability is associated with an MMP-9 activity increase in cerebral ischemia: both effects decreased by Ang-1. J Cereb Blood Flow Metab 2005; 25(11): 1491-504.
    • (2005) J Cereb Blood Flow Metab , vol.25 , Issue.11 , pp. 1491-1504
    • Valable, S.1    Montaner, J.2    Bellail, A.3
  • 33
    • 34648839855 scopus 로고    scopus 로고
    • Angiopoietin1/Tie2 and VEGF/Flk1 induced by MSC treatment amplifies angiogenesis and vascular stabilization after stroke
    • Zacharek A, Chen J, Cui X, et al. Angiopoietin1/Tie2 and VEGF/Flk1 induced by MSC treatment amplifies angiogenesis and vascular stabilization after stroke. J Cereb Blood Flow Metab 2007; 27(10): 1684-91.
    • (2007) J Cereb Blood Flow Metab , vol.27 , Issue.10 , pp. 1684-1691
    • Zacharek, A.1    Chen, J.2    Cui, X.3
  • 34
    • 34147117767 scopus 로고    scopus 로고
    • Advanced glycation end products cause increased CCN family and extracellular matrix gene expression in the diabetic rodent retina
    • Hughes JM, Kuiper EJ, Klaassen I, et al. Advanced glycation end products cause increased CCN family and extracellular matrix gene expression in the diabetic rodent retina. Diabetologia 2007; 50(5): 1089-98.
    • (2007) Diabetologia , vol.50 , Issue.5 , pp. 1089-1098
    • Hughes, J.M.1    Kuiper, E.J.2    Klaassen, I.3
  • 35
    • 0026333744 scopus 로고
    • Morphometric analysis of blood vessels in chronic experimental spinal cord injury: Hypervascularity and recovery of function
    • Blight AR. Morphometric analysis of blood vessels in chronic experimental spinal cord injury: hypervascularity and recovery of function. J Neurol Sci 1991; 106(2): 158-74.
    • (1991) J Neurol Sci , vol.106 , Issue.2 , pp. 158-174
    • Blight, A.R.1
  • 36
    • 0037369110 scopus 로고    scopus 로고
    • Von Willebrand factor
    • Ruggeri ZM. Von Willebrand factor. Curr Opin Hematol 2003; 10(2): 142-9.
    • (2003) Curr Opin Hematol , vol.10 , Issue.2 , pp. 142-149
    • Ruggeri, Z.M.1
  • 37
    • 51349102183 scopus 로고    scopus 로고
    • Von-Willebrand factor influences blood brain barrier permeability and brain inflammation in experimental allergic encephalomyelitis
    • Noubade R, del Rio R, McElvany B, et al. von-Willebrand factor influences blood brain barrier permeability and brain inflammation in experimental allergic encephalomyelitis. Am J Pathol 2008; 173(3): 892-900.
    • (2008) Am J Pathol , vol.173 , Issue.3 , pp. 892-900
    • Noubade, R.1    Del Rio, R.2    McElvany, B.3
  • 38
    • 0141705210 scopus 로고    scopus 로고
    • Blood-spinal cord barrier after spinal cord injury: Relation to revascularization and wound healing
    • Whetstone WD, Hsu JY, Eisenberg M, Werb Z, Noble-Haeusslein LJ. Blood-spinal cord barrier after spinal cord injury: relation to revascularization and wound healing. J Neurosci Res 2003; 74(2): 227-39.
    • (2003) J Neurosci Res , vol.74 , Issue.2 , pp. 227-239
    • Whetstone, W.D.1    Hsu, J.Y.2    Eisenberg, M.3    Werb, Z.4    Noble-Haeusslein, L.J.5
  • 39
    • 0035940295 scopus 로고    scopus 로고
    • Astrocyte-derived VEGF mediates survival and tube stabilization of hypoxic brain microvascular endothelial cells in vitro
    • Chow J, Ogunshola O, Fan SY, Li Y, Ment LR, Madri JA. Astrocyte-derived VEGF mediates survival and tube stabilization of hypoxic brain microvascular endothelial cells in vitro. Brain Res Dev Brain Res 2001; 130(1): 123-32.
    • (2001) Brain Res Dev Brain Res , vol.130 , Issue.1 , pp. 123-132
    • Chow, J.1    Ogunshola, O.2    Fan, S.Y.3    Li, Y.4    Ment, L.R.5    Madri, J.A.6
  • 40
    • 0242456268 scopus 로고    scopus 로고
    • Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival
    • Darland DC, Massingham LJ, Smith SR, Piek E, Saint-Geniez M, D'Amore PA. Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival. Dev Biol 2003; 264(1): 275-88.
    • (2003) Dev Biol , vol.264 , Issue.1 , pp. 275-288
    • Darland, D.C.1    Massingham, L.J.2    Smith, S.R.3    Piek, E.4    Saint-Geniez, M.5    D'Amore, P.A.6
  • 41
    • 20144387644 scopus 로고    scopus 로고
    • Exogenous Bcl-xL fusion protein spares neurons after spinal cord injury
    • Nesic-Taylor O, Cittelly D, Ye Z, et al. Exogenous Bcl-xL fusion protein spares neurons after spinal cord injury. J Neurosci Res 2005; 79(5): 628-37.
    • (2005) J Neurosci Res , vol.79 , Issue.5 , pp. 628-637
    • Nesic-Taylor, O.1    Cittelly, D.2    Ye, Z.3
  • 42
    • 0035074297 scopus 로고    scopus 로고
    • Temporal-spatial pattern of acute neuronal and glial loss after spinal cord contusion
    • Grossman SD, Rosenberg LJ, Wrathall JR. Temporal-spatial pattern of acute neuronal and glial loss after spinal cord contusion. Exp Neurol 2001; 168(2): 273-82.
    • (2001) Exp Neurol , vol.168 , Issue.2 , pp. 273-282
    • Grossman, S.D.1    Rosenberg, L.J.2    Wrathall, JR.3
  • 43
    • 65749108276 scopus 로고    scopus 로고
    • Neutralizing endogenous VEGF following traumatic spinal cord injury modulates microvascular plasticity but not tissue sparing or functional recovery
    • Benton RL, Maddie MA, Gruenthal MJ, Hagg T, Whittemore SR. Neutralizing endogenous VEGF following traumatic spinal cord injury modulates microvascular plasticity but not tissue sparing or functional recovery. Curr Neurovasc Res 2009; 6(2): 124-31.
    • (2009) Curr Neurovasc Res , vol.6 , Issue.2 , pp. 124-131
    • Benton, R.L.1    Maddie, M.A.2    Gruenthal, M.J.3    Hagg, T.4    Whittemore, SR.5
  • 44
    • 73049117998 scopus 로고    scopus 로고
    • An engineered transcription factor which activates VEGF-A enhances recovery after spinal cord injury
    • Liu Y, Figley S, Spratt SK, et al. An engineered transcription factor which activates VEGF-A enhances recovery after spinal cord injury. Neurobiol Dis 2010; 37(2): 384-93.
    • (2010) Neurobiol Dis , vol.37 , Issue.2 , pp. 384-393
    • Liu, Y.1    Figley, S.2    Spratt, S.K.3
  • 45
    • 19244379078 scopus 로고    scopus 로고
    • Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
    • Carmeliet P, Moons L, Luttun A, et al. Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med 2001; 7(5): 575-83.
    • (2001) Nat Med , vol.7 , Issue.5 , pp. 575-583
    • Carmeliet, P.1    Moons, L.2    Luttun, A.3
  • 46
    • 53149097323 scopus 로고    scopus 로고
    • Beneficial effects of prolonged systemic administration of PlGF on late outcome of post-ischaemic myocardial performance
    • Roncal C, Buysschaert I, Chorianopoulos E, et al. Beneficial effects of prolonged systemic administration of PlGF on late outcome of post-ischaemic myocardial performance. J Pathol 2008; 216(2): 236-44.
    • (2008) J Pathol , vol.216 , Issue.2 , pp. 236-244
    • Roncal, C.1    Buysschaert, I.2    Chorianopoulos, E.3
  • 47
    • 0036202011 scopus 로고    scopus 로고
    • Cell type-specific expression of neuropilins in an MCA-occlusion model in mice suggests a potential role in post-ischemic brain remodeling
    • Beck H, Acker T, Puschel AW, Fujisawa H, Carmeliet P, Plate KH. Cell type-specific expression of neuropilins in an MCA-occlusion model in mice suggests a potential role in post-ischemic brain remodeling. J Neuropathol Exp Neurol 2002; 61(4): 339-50.
    • (2002) J Neuropathol Exp Neurol , vol.61 , Issue.4 , pp. 339-350
    • Beck, H.1    Acker, T.2    Puschel, A.W.3    Fujisawa, H.4    Carmeliet, P.5    Plate, K.H.6
  • 48
  • 49
    • 0033678506 scopus 로고    scopus 로고
    • Expression of angiopoietin-1, angiopoietin-2, and tie receptors after middle cerebral artery occlusion in the rat
    • Beck H, Acker T, Wiessner C, Allegrini PR, Plate KH. Expression of angiopoietin-1, angiopoietin-2, and tie receptors after middle cerebral artery occlusion in the rat. Am J Pathol 2000; 157(5): 1473-83.
    • (2000) Am J Pathol , vol.157 , Issue.5 , pp. 1473-1483
    • Beck, H.1    Acker, T.2    Wiessner, C.3    Allegrini, P.R.4    Plate, K.H.5
  • 50
    • 77950810539 scopus 로고    scopus 로고
    • Rescuing vasculature with intravenous angiopoietin-1 and avβ3 integrin peptide is protective after spinal cord injury
    • Han S, Arnold SA, Sithu SD, et al. Rescuing vasculature with intravenous angiopoietin-1 and avβ3 integrin peptide is protective after spinal cord injury. Brain 2010; 133: 1026-42.
    • (2010) Brain , vol.133 , pp. 1026-1042
    • Han, S.1    Arnold, S.A.2    Sithu, S.D.3
  • 51
    • 1642521733 scopus 로고    scopus 로고
    • Cerebral angiogenesis induced by growth factors: Intravital microscopic studies using models
    • Niimi H. Cerebral angiogenesis induced by growth factors: intravital microscopic studies using models. Clin Hemorheol Microcirc 2003; 29(34): 149-56.
    • (2003) Clin Hemorheol Microcirc , vol.29 , Issue.3-4 , pp. 149-156
    • Niimi, H.1
  • 52
    • 17444393268 scopus 로고    scopus 로고
    • An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculature
    • Lehti K, Allen E, Birkedal-Hansen H, et al. An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculature. Genes Dev 2005; 19(8): 979-91.
    • (2005) Genes Dev , vol.19 , Issue.8 , pp. 979-991
    • Lehti, K.1    Allen, E.2    Birkedal-Hansen, H.3
  • 53
    • 0029866683 scopus 로고    scopus 로고
    • Cultured retinal capillary pericytes die by apoptosis after an abrupt fluctuation from high to low glucose levels: A comparative study with retinal capillary endothelial cells
    • Li W, Liu X, Yanoff M, Cohen S, Ye X. Cultured retinal capillary pericytes die by apoptosis after an abrupt fluctuation from high to low glucose levels: a comparative study with retinal capillary endothelial cells. Diabetologia 1996; 39(5): 537-47.
    • (1996) Diabetologia , vol.39 , Issue.5 , pp. 537-547
    • Li, W.1    Liu, X.2    Yanoff, M.3    Cohen, S.4    Ye, X.5
  • 54
    • 0030756325 scopus 로고    scopus 로고
    • Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
    • Lindahl P, Johansson BR, Leveen P, Betsholtz C. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science 1997; 277(5323): 242-5.
    • (1997) Science , vol.277 , Issue.5323 , pp. 242-245
    • Lindahl, P.1    Johansson, B.R.2    Leveen, P.3    Betsholtz, C.4
  • 55
    • 0027936261 scopus 로고
    • Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities
    • Leveen P, Pekny M, Gebre-Medhin S, Swolin B, Larsson E, Betsholtz C. Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities. Genes Dev 1994; 8(16): 1875-87.
    • (1994) Genes Dev , vol.8 , Issue.16 , pp. 1875-1887
    • Leveen, P.1    Pekny, M.2    Gebre-Medhin, S.3    Swolin, B.4    Larsson, E.5    Betsholtz, C.6
  • 56
    • 64249148750 scopus 로고    scopus 로고
    • Dual gene transfer of fibroblast growth factor-2 and platelet derived growth factor-BB using plasmid deoxyribonucleic acid promotes effective angiogenesis and arteriogenesis in a rodent model of hindlimb ischemia
    • de Paula EV, Flores-Nascimento MC, Arruda VR, Garcia RA, Ramos CD, Guillaumon AT, et al. Dual gene transfer of fibroblast growth factor-2 and platelet derived growth factor-BB using plasmid deoxyribonucleic acid promotes effective angiogenesis and arteriogenesis in a rodent model of hindlimb ischemia. Transl Res 2009; 153(5): 232-9.
    • (2009) Transl Res , vol.153 , Issue.5 , pp. 232-239
    • De Paula, E.V.1    Flores-Nascimento, M.C.2    Arruda, V.R.3    Garcia, R.A.4    Ramos, C.D.5    Guillaumon, A.T.6
  • 57
    • 77953545743 scopus 로고    scopus 로고
    • Synergistic effects of FGF-2 and PDGF-BB on angiogenesis and muscle regeneration in rabbit hindlimb ischemia model
    • Li J, Wei Y, Liu K, et al. Synergistic effects of FGF-2 and PDGF-BB on angiogenesis and muscle regeneration in rabbit hindlimb ischemia model. Microvasc Res 2010; 80(1): 10-7.
    • (2010) Microvasc Res , vol.80 , Issue.1 , pp. 10-17
    • Li, J.1    Wei, Y.2    Liu, K.3
  • 58
    • 0028049655 scopus 로고
    • Ischemia induces the expression of the platelet-derived growth factor-B chain in neurons and brain macrophages in vivo
    • Iihara K, Sasahara M, Hashimoto N, Uemura Y, Kikuchi H, Hazama F. Ischemia induces the expression of the platelet-derived growth factor-B chain in neurons and brain macrophages in vivo. J Cereb Blood Flow Metab 1994; 14(5): 818-24.
    • (1994) J Cereb Blood Flow Metab , vol.14 , Issue.5 , pp. 818-824
    • Iihara, K.1    Sasahara, M.2    Hashimoto, N.3    Uemura, Y.4    Kikuchi, H.5    Hazama, F.6
  • 59
    • 0032065993 scopus 로고    scopus 로고
    • Expression of platelet-derived growth factor after transient forebrain ischemia in the gerbil hippocampus
    • Kaneko M, Sasahara M, Takayama S, Handa J, Hazama F. Expression of platelet-derived growth factor after transient forebrain ischemia in the gerbil hippocampus. Acta Neuropathol 1998; 95(5): 471-8.
    • (1998) Acta Neuropathol , vol.95 , Issue.5 , pp. 471-478
    • Kaneko, M.1    Sasahara, M.2    Takayama, S.3    Handa, J.4    Hazama, F.5
  • 60
    • 0037906352 scopus 로고    scopus 로고
    • Time-and cell type-specific induction of platelet-derived growth factor receptor-beta during cerebral ischemia
    • Renner O, Tsimpas A, Kostin S, et al. Time-and cell type-specific induction of platelet-derived growth factor receptor-beta during cerebral ischemia. Brain Res Mol Brain Res 2003; 113(1-2): 44-51.
    • (2003) Brain Res Mol Brain Res , vol.113 , Issue.12 , pp. 44-51
    • Renner, O.1    Tsimpas, A.2    Kostin, S.3
  • 61
    • 60749108728 scopus 로고    scopus 로고
    • Roles of Platelet-Derived Growth Factor-B Expression in the Ventral Horn and Motor Cortex in the Spinal Cord-Hemisected Rhesus Monkey
    • Xiyang YB, Liu S, Liu J, et al. Roles of Platelet-Derived Growth Factor-B Expression in the Ventral Horn and Motor Cortex in the Spinal Cord-Hemisected Rhesus Monkey. J Neurotrauma 2009; 26(2): 275-87.
    • (2009) J Neurotrauma , vol.26 , Issue.2 , pp. 275-287
    • Xiyang, Y.B.1    Liu, S.2    Liu, J.3
  • 62
    • 44149090296 scopus 로고    scopus 로고
    • Role of platelet-derived growth factors in physiology and medicine
    • Andrae J, Gallini R, Betsholtz C. Role of platelet-derived growth factors in physiology and medicine. Genes Dev 2008; 22(10): 1276-312.
    • (2008) Genes Dev , vol.22 , Issue.10 , pp. 1276-1312
    • Andrae, J.1    Gallini, R.2    Betsholtz, C.3
  • 63
    • 0028014275 scopus 로고
    • Terminal complement proteins C5b-9 release basic fibroblast growth factor and platelet-derived growth factor from endothelial cells
    • Benzaquen LR, Nicholson-Weller A, Halperin JA. Terminal complement proteins C5b-9 release basic fibroblast growth factor and platelet-derived growth factor from endothelial cells. J Exp Med 1994; 179(3): 985-92.
    • (1994) J Exp Med , vol.179 , Issue.3 , pp. 985-992
    • Benzaquen, L.R.1    Nicholson-Weller, A.2    Halperin, J.A.3
  • 64
    • 0025350739 scopus 로고
    • Localization of PDGF-B protein in macrophages in all phases of atherogenesis
    • Ross R, Masuda J, Raines EW, et al. Localization of PDGF-B protein in macrophages in all phases of atherogenesis. Science 1990; 248(4958): 1009-12.
    • (1990) Science , vol.248 , Issue.4958 , pp. 1009-1012
    • Ross, R.1    Masuda, J.2    Raines, E.W.3
  • 65
    • 77949976466 scopus 로고    scopus 로고
    • Platelet-derived growth factor-induced severe and chronic vasoconstriction of cerebral arteries: Proposed growth factor explanation of cerebral vasospasm
    • discussion 35.
    • Zhang ZW, Yanamoto H, Nagata I, et al. Platelet-derived growth factor-induced severe and chronic vasoconstriction of cerebral arteries: proposed growth factor explanation of cerebral vasospasm. Neurosurgery 2010; 66(4): 728-35; discussion 35.
    • (2010) Neurosurgery , vol.66 , Issue.4 , pp. 728-735
    • Zhang, Z.W.1    Yanamoto, H.2    Nagata, I.3
  • 66
    • 0032477844 scopus 로고    scopus 로고
    • Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: The case for paracrine amplification of angiogenesis
    • Van Belle E, Witzenbichler B, Chen D, et al. Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: the case for paracrine amplification of angiogenesis. Circulation 1998; 97(4): 381-90.
    • (1998) Circulation , vol.97 , Issue.4 , pp. 381-390
    • Van Belle, E.1    Witzenbichler, B.2    Chen, D.3
  • 67
    • 36649029983 scopus 로고    scopus 로고
    • In vivo hepatocyte growth factor gene transfer reduces myocardial ischemia-reperfusion injury through its multiple actions
    • Chen XH, Minatoguchi S, Kosai K, et al. In vivo hepatocyte growth factor gene transfer reduces myocardial ischemia-reperfusion injury through its multiple actions. J Card Fail 2007; 13(10): 874-83.
    • (2007) J Card Fail , vol.13 , Issue.10 , pp. 874-883
    • Chen, X.H.1    Minatoguchi, S.2    Kosai, K.3
  • 68
    • 34248161509 scopus 로고    scopus 로고
    • Expression of hepatocyte growth factor and c-Met after spinal cord injury in rats
    • Shimamura M, Sato N, Sata M, Wakayama K, Ogihara T, Morishita R. Expression of hepatocyte growth factor and c-Met after spinal cord injury in rats. Brain Res 2007; 1151: 188-94.
    • (2007) Brain Res , vol.1151 , pp. 188-194
    • Shimamura, M.1    Sato, N.2    Sata, M.3    Wakayama, K.4    Ogihara, T.5    Morishita, R.6
  • 69
    • 34250671041 scopus 로고    scopus 로고
    • Contextual role for angiopoietins and TGFbeta1 in blood vessel stabilization
    • Ramsauer M, D'Amore PA. Contextual role for angiopoietins and TGFbeta1 in blood vessel stabilization. J Cell Sci 2007; 120(Pt 10): 1810-7.
    • (2007) J Cell Sci , vol.120 , Issue.PART 10 , pp. 1810-1817
    • Ramsauer, M.1    D'Amore, P.A.2
  • 70
    • 3242757526 scopus 로고    scopus 로고
    • TGF-beta induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways
    • Nakagawa T, Li JH, Garcia G, et al. TGF-beta induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways. Kidney Int 2004; 66(2): 605-13.
    • (2004) Kidney Int , vol.66 , Issue.2 , pp. 605-613
    • Nakagawa, T.1    Li, J.H.2    Garcia, G.3
  • 71
    • 30144440059 scopus 로고    scopus 로고
    • Transforming growth factor-β signal transduction in angionenesis and vascular disorders
    • Bertolino P, Deckers M, Lebrin F, ten Dijke P. Transforming growth factor-β signal transduction in angionenesis and vascular disorders. CHEST 2005; 128: 585S-90S.
    • (2005) CHEST , vol.128
    • Bertolino, P.1    Deckers, M.2    Lebrin, F.3    Ten Dijke, P.4
  • 72
    • 64549113715 scopus 로고    scopus 로고
    • TGF-beta is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature
    • Walshe TE, Saint-Geniez M, Maharaj AS, Sekiyama E, Maldonado AE, D'Amore PA. TGF-beta is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature. PLoS One 2009; 4(4): e5149.
    • (2009) PLoS One , vol.4 , Issue.4
    • Walshe, T.E.1    Saint-Geniez, M.2    Maharaj, A.S.3    Sekiyama, E.4    Maldonado, A.E.5    D'Amore, P.A.6
  • 74
    • 43049087096 scopus 로고    scopus 로고
    • TGF-beta1 and TGF-beta2 expression after traumatic human spinal cord injury
    • Buss A, Pech K, Kakulas BA, et al. TGF-beta1 and TGF-beta2 expression after traumatic human spinal cord injury. Spinal Cord 2008; 46(5): 364-71.
    • (2008) Spinal Cord , vol.46 , Issue.5 , pp. 364-371
    • Buss, A.1    Pech, K.2    Kakulas, B.A.3
  • 75
    • 0036017364 scopus 로고    scopus 로고
    • Expression of TGFbeta2 but not TGFbeta1 correlates with the deposition of scar tissue in the lesioned spinal cord
    • Lagord C, Berry M, Logan A. Expression of TGFbeta2 but not TGFbeta1 correlates with the deposition of scar tissue in the lesioned spinal cord. Mol Cell Neurosci 2002; 20(1): 69-92.
    • (2002) Mol Cell Neurosci , vol.20 , Issue.1 , pp. 69-92
    • Lagord, C.1    Berry, M.2    Logan, A.3
  • 76
    • 37249048319 scopus 로고    scopus 로고
    • TGF-beta in neural stem cells and in tumors of the central nervous system
    • Aigner L, Bogdahn U. TGF-beta in neural stem cells and in tumors of the central nervous system. Cell Tissue Res 2008; 331(1): 225-41.
    • (2008) Cell Tissue Res , vol.331 , Issue.1 , pp. 225-241
    • Aigner, L.1    Bogdahn, U.2
  • 77
    • 33845906843 scopus 로고    scopus 로고
    • All in the CCN family: Essential matricellular signaling modulators emerge from the bunker
    • Leask A, Abraham DJ. All in the CCN family: essential matricellular signaling modulators emerge from the bunker. J Cell Sci 2006; 119(Pt 23): 4803-10.
    • (2006) J Cell Sci , vol.119 , Issue.PART 23 , pp. 4803-4810
    • Leask, A.1    Abraham, D.J.2
  • 78
    • 0033541389 scopus 로고    scopus 로고
    • The CCN family of angiogenic regulators: The integrin connection
    • Lau LF, Lam SC. The CCN family of angiogenic regulators: the integrin connection. Exp Cell Res 1999; 248(1): 44-57.
    • (1999) Exp Cell Res , vol.248 , Issue.1 , pp. 44-57
    • Lau, L.F.1    Lam, S.C.2
  • 79
    • 2242453283 scopus 로고    scopus 로고
    • Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells
    • Leu SJ, Lam SC, Lau LF. Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells. J Biol Chem 2002; 277(48): 46248-55.
    • (2002) J Biol Chem , vol.277 , Issue.48 , pp. 46248-46255
    • Leu, S.J.1    Lam, S.C.2    Lau, L.F.3
  • 80
    • 0036385767 scopus 로고    scopus 로고
    • Stimulation of angiogenesis by Cyr61 gene: A new therapeutic candidate
    • Fataccioli V, Abergel V, Wingertsmann L, et al. Stimulation of angiogenesis by Cyr61 gene: a new therapeutic candidate. Hum Gene Ther 2002; 13(12): 1461-70.
    • (2002) Hum Gene Ther , vol.13 , Issue.12 , pp. 1461-1470
    • Fataccioli, V.1    Abergel, V.2    Wingertsmann, L.3
  • 81
    • 67649964636 scopus 로고    scopus 로고
    • Cysteine-rich 61, a member of the CCN family, as a factor involved in the pathogenesis of proliferative diabetic retinopathy
    • You JJ, Yang CH, Chen MS, Yang CM. Cysteine-rich 61, a member of the CCN family, as a factor involved in the pathogenesis of proliferative diabetic retinopathy. Invest Ophthalmol Vis Sci 2009; 50(7): 3447-55.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , Issue.7 , pp. 3447-3455
    • You, J.J.1    Yang, C.H.2    Chen, M.S.3    Yang, C.M.4
  • 82
    • 53349143521 scopus 로고    scopus 로고
    • A Key role for cyclic AMP-responsive element binding protein in hypoxia-mediated activation of the angiogenesis factor CCN1 (CYR61) in Tumor cells
    • Meyuhas R, Pikarsky E, Tavor E, et al. A Key role for cyclic AMP-responsive element binding protein in hypoxia-mediated activation of the angiogenesis factor CCN1 (CYR61) in Tumor cells. Mol Cancer Res 2008; 6(9): 1397-409.
    • (2008) Mol Cancer Res , vol.6 , Issue.9 , pp. 1397-1409
    • Meyuhas, R.1    Pikarsky, E.2    Tavor, E.3
  • 83
    • 77950799532 scopus 로고    scopus 로고
    • Cyr61 mediates hepatocyte growth factor-dependent tumor cell growth, migration, and Akt activation
    • Goodwin CR, Lal B, Zhou X, Ho S, Xia S, et al. Cyr61 mediates hepatocyte growth factor-dependent tumor cell growth, migration, and Akt activation. Cancer Res 2010; 70(7): 2932-41.
    • (2010) Cancer Res , vol.70 , Issue.7 , pp. 2932-2941
    • Goodwin, C.R.1    Lal, B.2    Zhou, X.3    Ho, S.4    Xia, S.5
  • 84
    • 77951921964 scopus 로고    scopus 로고
    • Matricellular protein CCN1 activates a proinflammatory genetic program in murine macrophages
    • Bai T, Chen CC, Lau LF. Matricellular protein CCN1 activates a proinflammatory genetic program in murine macrophages. J Immunol 2010; 184(6): 3223-32.
    • (2010) J Immunol , vol.184 , Issue.6 , pp. 3223-3232
    • Bai, T.1    Chen, C.C.2    Lau, L.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.