메뉴 건너뛰기




Volumn 25, Issue 1, 2011, Pages 28-36

Acute ethanol exposure disrupts actin cytoskeleton and generates reactive oxygen species in c6 cells

Author keywords

Actin; Cell morphology; Ethanol; Oxidative stress

Indexed keywords

ALCOHOL; ANTIOXIDANT; REACTIVE OXYGEN METABOLITE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; VINCULIN;

EID: 78650520910     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.09.003     Document Type: Article
Times cited : (25)

References (83)
  • 2
    • 0025267736 scopus 로고
    • Cytoskeleton as a target in menadione-induced oxidative stress in cultured mammalian cells. I. Biochemical and immunocytochemical features
    • Bellomo G., Mirabelli F., Vairetti M., Iosi F., Malorni W. Cytoskeleton as a target in menadione-induced oxidative stress in cultured mammalian cells. I. Biochemical and immunocytochemical features. J. Cell Physiol. 1990, 143:118-128.
    • (1990) J. Cell Physiol. , vol.143 , pp. 118-128
    • Bellomo, G.1    Mirabelli, F.2    Vairetti, M.3    Iosi, F.4    Malorni, W.5
  • 3
    • 0016206214 scopus 로고
    • Characteristics of the rat C-6 glioma maintained in organ culture systems. Production of glial fibrillary acidic protein in the absence of gliofibrillogenesis
    • Bissell M.G., Rubinstein L.J., Bignami A., Herman M.M. Characteristics of the rat C-6 glioma maintained in organ culture systems. Production of glial fibrillary acidic protein in the absence of gliofibrillogenesis. Brain Res. 1974, 82:77-89.
    • (1974) Brain Res. , vol.82 , pp. 77-89
    • Bissell, M.G.1    Rubinstein, L.J.2    Bignami, A.3    Herman, M.M.4
  • 4
    • 36048943866 scopus 로고    scopus 로고
    • Ethanol intake enhances inflammatory mediators in brain: role of glial cells and TLR4/IL-1RI receptors
    • Blanco A.M., Guerri C. Ethanol intake enhances inflammatory mediators in brain: role of glial cells and TLR4/IL-1RI receptors. Front. Biosci. 2007, 12:2616-2630.
    • (2007) Front. Biosci. , vol.12 , pp. 2616-2630
    • Blanco, A.M.1    Guerri, C.2
  • 5
    • 77956587996 scopus 로고    scopus 로고
    • Chronic ethanol exposure produces tolerance to elevations in neuroactive steroids: mechanisms and reversal by exogenous ACTH
    • Boyd K.N., Kumar S., O'Buckley T.K., Morrow A.L. Chronic ethanol exposure produces tolerance to elevations in neuroactive steroids: mechanisms and reversal by exogenous ACTH. J. Neurochem. 2010.
    • (2010) J. Neurochem.
    • Boyd, K.N.1    Kumar, S.2    O'Buckley, T.K.3    Morrow, A.L.4
  • 6
    • 70450123699 scopus 로고    scopus 로고
    • Resveratrol: a natural polyphenol with multiple chemopreventive properties
    • Brisdelli F., D'Andrea G., Bozzi A. Resveratrol: a natural polyphenol with multiple chemopreventive properties. Curr. Drug Metab. 2009, 10:530-546.
    • (2009) Curr. Drug Metab. , vol.10 , pp. 530-546
    • Brisdelli, F.1    D'Andrea, G.2    Bozzi, A.3
  • 7
    • 0032937280 scopus 로고    scopus 로고
    • Effects of ethanol on calcium homeostasis in the nervous system: implications for astrocytes
    • Catlin M.C., Guizzetti M., Costa L.G. Effects of ethanol on calcium homeostasis in the nervous system: implications for astrocytes. Mol. Neurobiol. 1999, 19:1-24.
    • (1999) Mol. Neurobiol. , vol.19 , pp. 1-24
    • Catlin, M.C.1    Guizzetti, M.2    Costa, L.G.3
  • 8
    • 3543113113 scopus 로고    scopus 로고
    • Intermediate filaments mediate cytoskeletal crosstalk
    • Chang L., Goldman R.D. Intermediate filaments mediate cytoskeletal crosstalk. Nat. Rev. Mol. Cell Biol. 2004, 5:601-613.
    • (2004) Nat. Rev. Mol. Cell Biol. , vol.5 , pp. 601-613
    • Chang, L.1    Goldman, R.D.2
  • 9
    • 0036216238 scopus 로고    scopus 로고
    • Ethanol exposure enhances cell death in the developing cerebral cortex: role of brain-derived neurotrophic factor and its signaling pathways
    • Climent E., Pascual M., Renau-Piqueras J., Guerri C. Ethanol exposure enhances cell death in the developing cerebral cortex: role of brain-derived neurotrophic factor and its signaling pathways. J. Neurosci. Res. 2002, 68:213-225.
    • (2002) J. Neurosci. Res. , vol.68 , pp. 213-225
    • Climent, E.1    Pascual, M.2    Renau-Piqueras, J.3    Guerri, C.4
  • 10
    • 0032213261 scopus 로고    scopus 로고
    • Cytoskeletal assembly and ATP release regulate astrocytic calcium signaling
    • Cotrina M.L., Lin J.H., Nedergaard M. Cytoskeletal assembly and ATP release regulate astrocytic calcium signaling. J. Neurosci. 1998, 18:8794-8804.
    • (1998) J. Neurosci. , vol.18 , pp. 8794-8804
    • Cotrina, M.L.1    Lin, J.H.2    Nedergaard, M.3
  • 12
    • 34249274957 scopus 로고    scopus 로고
    • Ethanol metabolism and effects: nitric oxide and its interaction
    • Deng X.S., Deitrich R.A. Ethanol metabolism and effects: nitric oxide and its interaction. Curr. Clin. Pharmacol. 2007, 2:145-153.
    • (2007) Curr. Clin. Pharmacol. , vol.2 , pp. 145-153
    • Deng, X.S.1    Deitrich, R.A.2
  • 13
    • 0141953237 scopus 로고    scopus 로고
    • Cytoskeletal dynamics and transport in growth cone motility and axon guidance
    • Dent E.W., Gertler F.B. Cytoskeletal dynamics and transport in growth cone motility and axon guidance. Neuron 2003, 40:209-227.
    • (2003) Neuron , vol.40 , pp. 209-227
    • Dent, E.W.1    Gertler, F.B.2
  • 14
    • 14844288299 scopus 로고    scopus 로고
    • Ethanol-induced neuroapoptosis in the developing rodent cerebellum and related brain stem structures
    • Dikranian K., Qin Y.Q., Labruyere J., Nemmers B., Olney J.W. Ethanol-induced neuroapoptosis in the developing rodent cerebellum and related brain stem structures. Brain Res. Dev. Brain Res. 2005, 155:1-13.
    • (2005) Brain Res. Dev. Brain Res. , vol.155 , pp. 1-13
    • Dikranian, K.1    Qin, Y.Q.2    Labruyere, J.3    Nemmers, B.4    Olney, J.W.5
  • 15
    • 0033501641 scopus 로고    scopus 로고
    • Glutamate induces rapid upregulation of astrocyte glutamate transport and cell-surface expression of GLAST
    • Duan S., Anderson C.M., Stein B.A., Swanson R.A. Glutamate induces rapid upregulation of astrocyte glutamate transport and cell-surface expression of GLAST. J. Neurosci. 1999, 19:10193-10200.
    • (1999) J. Neurosci. , vol.19 , pp. 10193-10200
    • Duan, S.1    Anderson, C.M.2    Stein, B.A.3    Swanson, R.A.4
  • 19
    • 25144493250 scopus 로고    scopus 로고
    • Branched-chain alpha-keto acids accumulating in maple syrup urine disease induce reorganization of phosphorylated GFAP in C6-glioma cells
    • Funchal C., Dos Santos A.Q., Jacques-Silva M.C., Zamoner A., Gottfried C., Wajner M., Pessoa-Pureur R. Branched-chain alpha-keto acids accumulating in maple syrup urine disease induce reorganization of phosphorylated GFAP in C6-glioma cells. Metab. Brain Dis. 2005, 20:205-217.
    • (2005) Metab. Brain Dis. , vol.20 , pp. 205-217
    • Funchal, C.1    Dos Santos, A.Q.2    Jacques-Silva, M.C.3    Zamoner, A.4    Gottfried, C.5    Wajner, M.6    Pessoa-Pureur, R.7
  • 20
    • 33750018948 scopus 로고    scopus 로고
    • Morphological alterations and induction of oxidative stress in glial cells caused by the branched-chain alpha-keto acids accumulating in maple syrup urine disease
    • Funchal C., Latini A., Jacques-Silva M.C., Dos Santos A.Q., Buzin L., Gottfried C., Wajner M., Pessoa-Pureur R. Morphological alterations and induction of oxidative stress in glial cells caused by the branched-chain alpha-keto acids accumulating in maple syrup urine disease. Neurochem. Int. 2006, 49:640-650.
    • (2006) Neurochem. Int. , vol.49 , pp. 640-650
    • Funchal, C.1    Latini, A.2    Jacques-Silva, M.C.3    Dos Santos, A.Q.4    Buzin, L.5    Gottfried, C.6    Wajner, M.7    Pessoa-Pureur, R.8
  • 22
    • 0033129605 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein (GFAP): modulation by growth factors and its implication in astrocyte differentiation
    • Gomes F.C., Paulin D., Moura Neto V. Glial fibrillary acidic protein (GFAP): modulation by growth factors and its implication in astrocyte differentiation. Braz. J. Med. Biol. Res. 1999, 32:619-631.
    • (1999) Braz. J. Med. Biol. Res. , vol.32 , pp. 619-631
    • Gomes, F.C.1    Paulin, D.2    Moura Neto, V.3
  • 23
    • 35448999182 scopus 로고    scopus 로고
    • 2+ mobilization and increases GFAP content in rat hippocampal astrocytes
    • 2+ mobilization and increases GFAP content in rat hippocampal astrocytes. Brain Res. 2007, 1178:28-37.
    • (2007) Brain Res. , vol.1178 , pp. 28-37
    • Gonzalez, A.1    Pariente, J.A.2    Salido, G.M.3
  • 24
    • 21744445111 scopus 로고    scopus 로고
    • The actin cytoskeleton: a key regulator of apoptosis and ageing?
    • Gourlay C.W., Ayscough K.R. The actin cytoskeleton: a key regulator of apoptosis and ageing?. Nat. Rev. Mol. Cell Biol. 2005, 6:583-589.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 583-589
    • Gourlay, C.W.1    Ayscough, K.R.2
  • 25
    • 0242516021 scopus 로고    scopus 로고
    • RhoA and lysophosphatidic acid are involved in the actin cytoskeleton reorganization of astrocytes exposed to ethanol
    • Guasch R.M., Tomas M., Minambres R., Valles S., Renau-Piqueras J., Guerri C. RhoA and lysophosphatidic acid are involved in the actin cytoskeleton reorganization of astrocytes exposed to ethanol. J. Neurosci. Res. 2003, 72:487-502.
    • (2003) J. Neurosci. Res. , vol.72 , pp. 487-502
    • Guasch, R.M.1    Tomas, M.2    Minambres, R.3    Valles, S.4    Renau-Piqueras, J.5    Guerri, C.6
  • 26
    • 0002516157 scopus 로고    scopus 로고
    • The effects of ethanol on glial cell proliferation: relevance to the fetal alcohol syndrome
    • Guizzetti M., Catlin M., Costa L.G. The effects of ethanol on glial cell proliferation: relevance to the fetal alcohol syndrome. Front. Biosci. 1997, 2:e93-98.
    • (1997) Front. Biosci. , vol.2
    • Guizzetti, M.1    Catlin, M.2    Costa, L.G.3
  • 27
    • 0031431084 scopus 로고    scopus 로고
    • Effect of ammonium chloride on energy metabolism of astrocytes and C6-glioma cells in vitro
    • Haghighat N., McCandless D.W. Effect of ammonium chloride on energy metabolism of astrocytes and C6-glioma cells in vitro. Metab. Brain Dis. 1997, 12:287-298.
    • (1997) Metab. Brain Dis. , vol.12 , pp. 287-298
    • Haghighat, N.1    McCandless, D.W.2
  • 28
    • 0033790679 scopus 로고    scopus 로고
    • The effect of ammonium chloride on metabolism of primary neurons and neuroblastoma cells in vitro
    • Haghighat N., McCandless D.W., Geraminegad P. The effect of ammonium chloride on metabolism of primary neurons and neuroblastoma cells in vitro. Metab. Brain Dis. 2000, 15:151-162.
    • (2000) Metab. Brain Dis. , vol.15 , pp. 151-162
    • Haghighat, N.1    McCandless, D.W.2    Geraminegad, P.3
  • 32
    • 53849120554 scopus 로고    scopus 로고
    • Mechanisms of ethanol-induced degeneration in the developing, mature, and aging cerebellum
    • Jaatinen P., Rintala J. Mechanisms of ethanol-induced degeneration in the developing, mature, and aging cerebellum. Cerebellum 2008, 7:332-347.
    • (2008) Cerebellum , vol.7 , pp. 332-347
    • Jaatinen, P.1    Rintala, J.2
  • 33
    • 0027076088 scopus 로고
    • Kinetics of ethanol and methanol in alcoholics during detoxification
    • Jones A.W., Sternebring B. Kinetics of ethanol and methanol in alcoholics during detoxification. Alcohol Alcohol 1992, 27:641-647.
    • (1992) Alcohol Alcohol , vol.27 , pp. 641-647
    • Jones, A.W.1    Sternebring, B.2
  • 35
    • 69249088090 scopus 로고    scopus 로고
    • Structural plasticity in actin and tubulin polymer dynamics
    • Kueh H.Y., Mitchison T.J. Structural plasticity in actin and tubulin polymer dynamics. Science 2009, 325:960-963.
    • (2009) Science , vol.325 , pp. 960-963
    • Kueh, H.Y.1    Mitchison, T.J.2
  • 37
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 39
    • 42049092972 scopus 로고    scopus 로고
    • Regulation of actin assembly associated with protrusion and adhesion in cell migration
    • Le Clainche C., Carlier M.F. Regulation of actin assembly associated with protrusion and adhesion in cell migration. Physiol. Rev. 2008, 88:489-513.
    • (2008) Physiol. Rev. , vol.88 , pp. 489-513
    • Le Clainche, C.1    Carlier, M.F.2
  • 41
    • 0030273614 scopus 로고    scopus 로고
    • GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination
    • Liedtke W., Edelmann W., Bieri P.L., Chiu F.C., Cowan N.J., Kucherlapati R., Raine C.S. GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination. Neuron 1996, 17:607-615.
    • (1996) Neuron , vol.17 , pp. 607-615
    • Liedtke, W.1    Edelmann, W.2    Bieri, P.L.3    Chiu, F.C.4    Cowan, N.J.5    Kucherlapati, R.6    Raine, C.S.7
  • 42
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 47
    • 0024326484 scopus 로고
    • Early and late passage C-6 glial cell growth: similarities with primary glial cells in culture
    • Mangoura D., Sakellaridis N., Jones J., Vernadakis A. Early and late passage C-6 glial cell growth: similarities with primary glial cells in culture. Neurochem. Res. 1989, 14:941-947.
    • (1989) Neurochem. Res. , vol.14 , pp. 941-947
    • Mangoura, D.1    Sakellaridis, N.2    Jones, J.3    Vernadakis, A.4
  • 49
    • 0030978990 scopus 로고    scopus 로고
    • Suppression by ethanol of inducible nitric oxide synthase expression in C6 glioma cells
    • Militante J.D., Feinstein D.L., Syapin P.J. Suppression by ethanol of inducible nitric oxide synthase expression in C6 glioma cells. J. Pharmacol. Exp. Ther. 1997, 281:558-565.
    • (1997) J. Pharmacol. Exp. Ther. , vol.281 , pp. 558-565
    • Militante, J.D.1    Feinstein, D.L.2    Syapin, P.J.3
  • 50
    • 0002335810 scopus 로고
    • Effect of prenatal exposure to ethanol on cell proliferation and neuronal migration
    • Wiley-Liss, New York, M. Miller (Ed.)
    • Miller M. Effect of prenatal exposure to ethanol on cell proliferation and neuronal migration. Development of the Central Nervous System. Effects of Alcohol and Opiates 1992, 47-69. Wiley-Liss, New York. M. Miller (Ed.).
    • (1992) Development of the Central Nervous System. Effects of Alcohol and Opiates , pp. 47-69
    • Miller, M.1
  • 51
    • 77956291813 scopus 로고    scopus 로고
    • A differential role for neuropeptides in acute and chronic adaptive responses to alcohol: behavioural and genetic analysis in Caenorhabditis elegans
    • Mitchell P., Mould R., Dillon J., Glautier S., Andrianakis I., James C., Pugh A., Holden-Dye L., O'Connor V. A differential role for neuropeptides in acute and chronic adaptive responses to alcohol: behavioural and genetic analysis in Caenorhabditis elegans. PLoS One 2010, 5:e10422.
    • (2010) PLoS One , vol.5
    • Mitchell, P.1    Mould, R.2    Dillon, J.3    Glautier, S.4    Andrianakis, I.5    James, C.6    Pugh, A.7    Holden-Dye, L.8    O'Connor, V.9
  • 52
    • 77951609645 scopus 로고    scopus 로고
    • Differential effects of acute and chronic ethanol exposure on orexin expression in the perifornical lateral hypothalamus
    • Morganstern I., Chang G.Q., Barson J.R., Ye Z., Karatayev O., Leibowitz S.F. Differential effects of acute and chronic ethanol exposure on orexin expression in the perifornical lateral hypothalamus. Alcohol Clin. Exp. Res. 2010, 34:886-896.
    • (2010) Alcohol Clin. Exp. Res. , vol.34 , pp. 886-896
    • Morganstern, I.1    Chang, G.Q.2    Barson, J.R.3    Ye, Z.4    Karatayev, O.5    Leibowitz, S.F.6
  • 55
    • 77649245096 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibitors partially inhibit oxidative stress development in the rat brain during sepsis provoked by cecal ligation and puncture
    • Ninkovic, M.B., Malicevic, Z.M., Jelenkovic, A., Dukic, M.M., Jovanovic, M.D., Stevanovic, I.D., 2009. Nitric oxide synthase inhibitors partially inhibit oxidative stress development in the rat brain during sepsis provoked by cecal ligation and puncture. Gen. Physiol. Biophys. 28, 243-250.
    • (2009) Gen. Physiol. Biophys. , vol.28 , pp. 243-250
    • Ninkovic, M.B.1    Malicevic, Z.M.2    Jelenkovic, A.3    Dukic, M.M.4    Jovanovic, M.D.5    Stevanovic, I.D.6
  • 56
    • 0032779365 scopus 로고    scopus 로고
    • Enhanced caspase activity during ethanol-induced apoptosis in rat cerebellar granule cells
    • Oberdoerster J., Rabin R.A. Enhanced caspase activity during ethanol-induced apoptosis in rat cerebellar granule cells. Eur. J. Pharmacol. 1999, 385:273-282.
    • (1999) Eur. J. Pharmacol. , vol.385 , pp. 273-282
    • Oberdoerster, J.1    Rabin, R.A.2
  • 58
    • 0034483953 scopus 로고    scopus 로고
    • Ethanol-induced apoptotic neurodegeneration in the developing brain
    • Olney J.W., Ishimaru M.J., Bittigau P., Ikonomidou C. Ethanol-induced apoptotic neurodegeneration in the developing brain. Apoptosis 2000, 5:515-521.
    • (2000) Apoptosis , vol.5 , pp. 515-521
    • Olney, J.W.1    Ishimaru, M.J.2    Bittigau, P.3    Ikonomidou, C.4
  • 60
    • 0036909375 scopus 로고    scopus 로고
    • Effect of exogenous melatonin on ethanol-induced changes in Na(+), K(+)- and Ca(2+)-ATPase activities in rat synaptosomes
    • Oner P., Cinar F., Koçak H., Gürdöl F. Effect of exogenous melatonin on ethanol-induced changes in Na(+), K(+)- and Ca(2+)-ATPase activities in rat synaptosomes. Neurochem. Res. 2002, 27:1619-1623.
    • (2002) Neurochem. Res. , vol.27 , pp. 1619-1623
    • Oner, P.1    Cinar, F.2    Koçak, H.3    Gürdöl, F.4
  • 61
    • 0019224249 scopus 로고
    • "Transdifferentiation" of C6 glial cells in culture
    • Parker K.K., Norenberg M.D., Vernadakis A. "Transdifferentiation" of C6 glial cells in culture. Science 1980, 208:179-181.
    • (1980) Science , vol.208 , pp. 179-181
    • Parker, K.K.1    Norenberg, M.D.2    Vernadakis, A.3
  • 62
    • 33847016938 scopus 로고    scopus 로고
    • Intermittent ethanol exposure induces inflammatory brain damage and causes long-term behavioural alterations in adolescent rats
    • Pascual M., Blanco A.M., Cauli O., Minarro J., Guerri C. Intermittent ethanol exposure induces inflammatory brain damage and causes long-term behavioural alterations in adolescent rats. Eur. J. Neurosci. 2007, 25:541-550.
    • (2007) Eur. J. Neurosci. , vol.25 , pp. 541-550
    • Pascual, M.1    Blanco, A.M.2    Cauli, O.3    Minarro, J.4    Guerri, C.5
  • 63
    • 0002225166 scopus 로고
    • Effects of alcohol on the development of glial cells and myelin
    • CRC Press, Boca Raton, R. Watson (Ed.)
    • Phillips D. Effects of alcohol on the development of glial cells and myelin. Alcohol and Neurobiology. Brain Development and Hormone Regulation 1992, 83-108. CRC Press, Boca Raton. R. Watson (Ed.).
    • (1992) Alcohol and Neurobiology. Brain Development and Hormone Regulation , pp. 83-108
    • Phillips, D.1
  • 64
    • 68449083925 scopus 로고    scopus 로고
    • Resveratrol protects spatial learning in middle-aged C57BL/6 mice from effects of ethanol
    • Ranney A., Petro M.S. Resveratrol protects spatial learning in middle-aged C57BL/6 mice from effects of ethanol. Behav. Pharmacol. 2009, 20:330-336.
    • (2009) Behav. Pharmacol. , vol.20 , pp. 330-336
    • Ranney, A.1    Petro, M.S.2
  • 66
    • 0026778133 scopus 로고
    • The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
    • Ridley A.J., Hall A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 1992, 70:389-399.
    • (1992) Cell , vol.70 , pp. 389-399
    • Ridley, A.J.1    Hall, A.2
  • 67
    • 33749058095 scopus 로고    scopus 로고
    • Distinct behavioral responses to ethanol are regulated by alternate RhoGAP18B isoforms
    • Rothenfluh A., Threlkeld R.J., Bainton R.J., Tsai L.T., Lasek A.W., Heberlein U. Distinct behavioral responses to ethanol are regulated by alternate RhoGAP18B isoforms. Cell 2006, 127:199-211.
    • (2006) Cell , vol.127 , pp. 199-211
    • Rothenfluh, A.1    Threlkeld, R.J.2    Bainton, R.J.3    Tsai, L.T.4    Lasek, A.W.5    Heberlein, U.6
  • 68
    • 0021239477 scopus 로고
    • Ethanol-induced microcephaly in neonatal rats: relation to dose
    • Samson H.H., Grant K.A. Ethanol-induced microcephaly in neonatal rats: relation to dose. Alcohol Clin. Exp. Res. 1984, 8:201-203.
    • (1984) Alcohol Clin. Exp. Res. , vol.8 , pp. 201-203
    • Samson, H.H.1    Grant, K.A.2
  • 69
    • 35448949092 scopus 로고    scopus 로고
    • The Oct DNA motif participates in the alcohol inhibition of the inducible nitric oxide synthase gene promoter in rat C6 glioma cells
    • Sanchez A.C., Davis R.L., Syapin P.J. The Oct DNA motif participates in the alcohol inhibition of the inducible nitric oxide synthase gene promoter in rat C6 glioma cells. Brain Res. 2007, 1179:16-27.
    • (2007) Brain Res. , vol.1179 , pp. 16-27
    • Sanchez, A.C.1    Davis, R.L.2    Syapin, P.J.3
  • 70
    • 33644519960 scopus 로고    scopus 로고
    • Astrocyte dysfunction in neurological disorders: a molecular perspective
    • Seifert G., Schilling K., Steinhauser C. Astrocyte dysfunction in neurological disorders: a molecular perspective. Nat. Rev. Neurosci. 2006, 7:194-206.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 194-206
    • Seifert, G.1    Schilling, K.2    Steinhauser, C.3
  • 71
    • 0034031850 scopus 로고    scopus 로고
    • Disruption of actin cytoskeleton in cultured rat astrocytes suppresses ATP- and bradykinin-induced [Ca(2+)](i) oscillations by reducing the coupling efficiency between Ca(2+) release, capacitative Ca(2+) entry, and store refilling
    • Sergeeva M., Ubl J.J., Reiser G. Disruption of actin cytoskeleton in cultured rat astrocytes suppresses ATP- and bradykinin-induced [Ca(2+)](i) oscillations by reducing the coupling efficiency between Ca(2+) release, capacitative Ca(2+) entry, and store refilling. Neuroscience 2000, 97:765-769.
    • (2000) Neuroscience , vol.97 , pp. 765-769
    • Sergeeva, M.1    Ubl, J.J.2    Reiser, G.3
  • 73
    • 0035137016 scopus 로고    scopus 로고
    • Ethanol and oxidative mechanisms in the brain
    • Sun A.Y., Sun G.Y. Ethanol and oxidative mechanisms in the brain. J. Biomed. Sci. 2001, 8:37-43.
    • (2001) J. Biomed. Sci. , vol.8 , pp. 37-43
    • Sun, A.Y.1    Sun, G.Y.2
  • 74
    • 0034912640 scopus 로고    scopus 로고
    • Cytokine-induced iNOS expression in C6 glial cells: transcriptional inhibition by ethanol
    • Syapin P.J., Militante J.D., Garrett D.K., Ren L. Cytokine-induced iNOS expression in C6 glial cells: transcriptional inhibition by ethanol. J. Pharmacol. Exp. Ther. 2001, 298:744-752.
    • (2001) J. Pharmacol. Exp. Ther. , vol.298 , pp. 744-752
    • Syapin, P.J.1    Militante, J.D.2    Garrett, D.K.3    Ren, L.4
  • 75
    • 33644836737 scopus 로고    scopus 로고
    • Nitric oxide, a biological double-faced janus - is this good or bad?
    • Thippeswamy T., McKay J.S., Quinn J.P., Morris R. Nitric oxide, a biological double-faced janus - is this good or bad?. Histol. Histopathol. 2006, 21:445-458.
    • (2006) Histol. Histopathol. , vol.21 , pp. 445-458
    • Thippeswamy, T.1    McKay, J.S.2    Quinn, J.P.3    Morris, R.4
  • 76
    • 67649641781 scopus 로고    scopus 로고
    • Suppression of neuro-inflammatory signaling cascade by tocotrienol can prevent chronic alcohol-induced cognitive dysfunction in rats
    • Tiwari V., Kuhad A., Chopra K. Suppression of neuro-inflammatory signaling cascade by tocotrienol can prevent chronic alcohol-induced cognitive dysfunction in rats. Behav. Brain Res. 2009, 203:296-303.
    • (2009) Behav. Brain Res. , vol.203 , pp. 296-303
    • Tiwari, V.1    Kuhad, A.2    Chopra, K.3
  • 77
    • 0141531091 scopus 로고    scopus 로고
    • Protective effects of lysophosphatidic acid (LPA) on chronic ethanol-induced injuries to the cytoskeleton and on glucose uptake in rat astrocytes
    • Tomas M., Lazaro-Dieguez F., Duran J.M., Marin P., Renau-Piqueras J., Egea G. Protective effects of lysophosphatidic acid (LPA) on chronic ethanol-induced injuries to the cytoskeleton and on glucose uptake in rat astrocytes. J. Neurochem. 2003, 87:220-229.
    • (2003) J. Neurochem. , vol.87 , pp. 220-229
    • Tomas, M.1    Lazaro-Dieguez, F.2    Duran, J.M.3    Marin, P.4    Renau-Piqueras, J.5    Egea, G.6
  • 79
    • 0019797712 scopus 로고
    • Blood ethanol levels in sober alcohol users seen in an emergency room
    • Urso T., Gavaler J.S., Van Thiel D.H. Blood ethanol levels in sober alcohol users seen in an emergency room. Life Sci. 1981, 28:1053-1056.
    • (1981) Life Sci. , vol.28 , pp. 1053-1056
    • Urso, T.1    Gavaler, J.S.2    Van Thiel, D.H.3
  • 81
    • 0025675639 scopus 로고
    • Type II glucocorticoid receptors are expressed in oligodendrocytes and astrocytes
    • Vielkind U., Walencewicz A., Levine J.M., Bohn M.C. Type II glucocorticoid receptors are expressed in oligodendrocytes and astrocytes. J. Neurosci. Res. 1990, 27:360-373.
    • (1990) J. Neurosci. Res. , vol.27 , pp. 360-373
    • Vielkind, U.1    Walencewicz, A.2    Levine, J.M.3    Bohn, M.C.4
  • 82
    • 0035137808 scopus 로고    scopus 로고
    • Ethanol inhibits cytokine-induced iNOS and sPLA2 in immortalized astrocytes: evidence for posttranscriptional site of ethanol action
    • Wang J.H., Sun G.Y. Ethanol inhibits cytokine-induced iNOS and sPLA2 in immortalized astrocytes: evidence for posttranscriptional site of ethanol action. J. Biomed. Sci. 2001, 8:126-133.
    • (2001) J. Biomed. Sci. , vol.8 , pp. 126-133
    • Wang, J.H.1    Sun, G.Y.2
  • 83
    • 0032544302 scopus 로고    scopus 로고
    • Ethanol modulates induction of nitric oxide synthase in glial cells by endotoxin
    • Wang J.Y., Shum A.Y., Hwang C.P. Ethanol modulates induction of nitric oxide synthase in glial cells by endotoxin. Life Sci. 1998, 63:1571-1583.
    • (1998) Life Sci. , vol.63 , pp. 1571-1583
    • Wang, J.Y.1    Shum, A.Y.2    Hwang, C.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.