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Volumn 46, Issue 1, 2011, Pages 1-10
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Synthesis, biological assessment and molecular modeling of new dihydroquinoline-3-carboxamides and dihydroquinoline-3-carbohydrazide derivatives as cholinesterase inhibitors, and Ca channel antagonists
a
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Author keywords
AChE; Alzheimer's disease; BuChE; Ca channel antagonism; Dihydroquinoline 3 carbohydrazides; Dihydroquinoline 3 carboxamides; hexahydropyrimido 5,4 c quinoline 2,5 diones; Molecular modeling
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Indexed keywords
3 ETHYL 4 METHYL 7 NITRO 6,10B DIHYDROPYRIMIDO[5,4 C]QUINOLINE 2,5(1H,3H) DIONE;
3,4 DIMETHYL 7 NITRO 6,10B DIHYDROPYRIMIDO[5,4 C]QUINOLINE 2,5(1H,3H) DIONE;
4 HYDROXY 1 METHYL N' [(2 NITROPHENYL)METHYLENE] 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOHYDRAZIDE;
4 HYDROXY 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOHYDRAZIDE;
4 HYDROXY 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOXAMIDE;
4 HYDROXY N' [(2 HYDROXY 5 METHOXYPHENYL)METHYLENE] 1 METHYL 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOHYDRAZIDE;
4 HYDROXY N' [(2 HYDROXY 5 METHOXYPHENYL)METHYLENE] 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOHYDRAZIDE;
4 HYDROXY N' [(2 HYDROXY 5 METHYLPHENYL)METHYLENE] 1 METHYL 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOHYDRAZIDE;
4 HYDROXY N' [(2 HYDROXY 5 METHYLPHENYL)METHYLENE] 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOHYDRAZIDE;
4 HYDROXY N' [(2 NITROPHENYL)METHYLENE] 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOHYDRAZIDE;
5 CHLORO N' [(2,4 DIHYDROXYPHENYL)METHYLIDENE] 4 HYDROXY 1 METHYL 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOHYDRAZIDE;
5 CHLORO N' [(2,4 DIHYDROXYPHENYL)METHYLIDENE] 4 HYDROXY 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOHYDRAZIDE;
ACETYLCHOLINESTERASE;
CALCIUM CHANNEL BLOCKING AGENT;
CHOLINESTERASE INHIBITOR;
HEXAHYDROPYRIMIDO[5,4 C]QUINOLINE 2,5 DIONE DERIVATIVE;
N [2 [(2 AMINOETHYL)AMINO]ETHYL] 4 HYDROXY 1 METHYL 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOXAMIDE;
N [2 [(2 AMINOETHYL)AMINO]ETHYL] 4 HYDROXY 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOXAMIDE;
N [2 [[2 [(2 AMINOETHYL)AMINO]ETHYL]AMINO]ETHYL] 4 HYDROXY 1 METHYL 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOXAMIDE;
N [2 [[2 [(2 AMINOETHYL)AMINO]ETHYL]AMINO]ETHYL] 4 HYDROXY 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOXAMIDE;
N' [(2,4 DIHYDROXYPHENYL)METHYLIDENE] 4 HYDROXY 1 METHYL 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOHYDRAZIDE;
N' [(2,4 DIHYDROXYPHENYL)METHYLIDENE] 4 HYDROXY 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOHYDRAZIDE;
N' [(2,6 DICHLORO 3 NITROPHENYL)METHYLENE] 4 HYDROXY 1 METHYL 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOHYDRAZIDE;
N' [(2,6 DICHLORO 3 NITROPHENYL)METHYLENE] 4 HYDROXY 2 OXO 1,2 DIHYDROQUINOLINE 3 CARBOHYDRAZIDE;
TACRINE;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ARTICLE;
CHOLINESTERASE INHIBITION;
CHROMAFFIN CELL;
DRUG STRUCTURE;
DRUG SYNTHESIS;
IC 50;
MOLECULAR DOCKING;
MOLECULAR MODEL;
NONHUMAN;
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EID: 78650513076
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2010.08.054 Document Type: Article |
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Times cited : (53)
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References (35)
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