Design, synthesis and evaluation of isaindigotone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 13, 2008, Pages 3790-3793

  Pan, Li ^a   Tan, Jia Heng ^a   Hou, Jin Qiang ^a   Huang, Shi Liang ^a   Gu, Lian Quan ^a   Huang, Zhi Shu ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Acetylcholinesterase inhibitors; Butyrylcholinesterase inhibitors; Isaindigotone derivatives

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ISAINDIGOTONE DERIVATIVE; TACRINE;

ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ACETYLCHOLINESTERASE; ALKALOIDS; BINDING SITES; BUTYRYLCHOLINESTERASE; CHEMISTRY, PHARMACEUTICAL; CHOLINESTERASE INHIBITORS; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; MODELS, CHEMICAL; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; QUINAZOLINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 44849113496     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.05.039     Document Type: Article

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