Alzheimer disease and oxidative stress

Journal of Biomedicine and Biotechnology

Volumn 2002, Issue 3, 2002, Pages 120-123

  Perry, George ^a   Cash, Adam D ^a   Smith, Mark A ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; IRON; TRANSITION ELEMENT;

ALZHEIMER DISEASE; HUMAN; MEDICAL RESEARCH; NEUROFIBRILLARY TANGLE; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOGENESIS; REVIEW; SENILE PLAQUE;

EID: 29844432499     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/S1110724302203010     Document Type: Review

References (19)

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2. Smith MA, Harris PLR, Sayre LM, Beckman JS, Perry G. Widespread peroxynitrite-mediated damage in Alzheimer's disease. J Neurosci. 1997;17(8):2653-6537.
3. Montine TJ, Amarnath V, Martin ME, Strittmatter WJ, Graham DG. E-4-hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures. Am J Pathol. 1996;148(1):89-93.
4. Sayre LM, Zelasko DA, Harris PL, Perry G, Salomon RG, Smith MA. 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J Neurochem. 1997;68(5):2092-2097.
5. Smith CD, Carney JM, Starke-Reed PE, et al. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. Proc Natl Acad Sci USA. 1991;88(23):10540-10543.
6. Smith MA, Rudnicka-Nawrot M, Richey PL, et al. Carbonyl-related posttranslational modification of neurofilament protein in the neurofibrillary pathology of Alzheimer's disease. J Neurochem. 1995;64(6):2660-2666.
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8. Premkumar DR, Smith MA, Richey PL, et al. Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer's disease. J Neurochem. 1995;65(3):1399-1402.
9. Takeda A, Smith MA, Avila J, et al. In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of τ induced by 4-hydroxy-2-nonenal modification. J Neurochem. 2000;75(3):1234-1241.
10. Smith MA, Sayre LM, Monnier VM, Perry G. Radical AGEing in Alzheimer's disease. Trends Neurosci. 1995;18(4):172-176.
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13. Nunomura A, Perry G, Pappolla MA, et al. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J Neurosci. 1999;19(6):1959-1964.
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