Chemiluminescent high-throughput microassay applied to imidazo[2,1-b]thiazole derivatives as potential acetylcholinesterase and butyrylcholinesterase inhibitors

European Journal of Medicinal Chemistry

Volumn 43, Issue 3, 2008, Pages 657-661

  Andreani, Aldo ^a   Burnelli, Silvia ^a   Granaiola, Massimiliano ^a   Guardigli, Massimo ^a   Leoni, Alberto ^a   Locatelli, Alessandra ^a   Morigi, Rita ^a   Rambaldi, Mirella ^a   Rizzoli, Manuela ^a   Varoli, Lucilla ^a   Roda, Aldo ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Antiacetylcholinesterase activity; Antibutyrylcholinesterase activity; Chemiluminescence; Imidazo 2,1 b thiazole

Indexed keywords

CHOLINESTERASE INHIBITOR; IMIDAZO[2,1 BETA]THIAZOLE DERIVATIVE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ACYLATION; ALKYLATION; ARTICLE; CHEMOLUMINESCENCE; DRUG ACTIVITY; DRUG INHIBITION; DRUG POTENCY; DRUG SYNTHESIS; HIGH THROUGHPUT SCREENING;

EID: 40049109945     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.04.018     Document Type: Article

References (23)

1. M.K. Gentry B.P. Doctor J. Massoulié F. Bacou E.A. Barnard A. Chatonnet B.P. Doctor D.M. Quinn Cholinesterases: Structure, Function, Mechanism, Genetics and Cell Biology 1991 American Chemical Society Washington, DC 394 398
2. A. Saxena A.M. Redman X. Jiang O. Lockridge B.P. Doctor Biochemistry 36 1997 14642 14651
3. M. Mesulam E. Giacobini Cholinesterases and Cholinesterase Inhibitors 2000 Martin Donitz London 121 137
4. E. Giacobini Int. J. Geriatr. Psychiatry 18 2003 S1 S5
5. E. Giacobini J.J. Buccafusco Cognitive Enhancing Drugs 2004 Birkhäuser Basel–Boston–Berlin 11 36
6. A. Tasker E.K. Perry C.G. Ballard Expert. Rev. Neurother. 5 2005 101 106
7. N.H. Greig T. Utsuki Q. Yu X. Zhu H.W. Holloway T. Perry B. Lee D.K. Ingram D.K. Lahiri Curr. Med. Res. Opin. 17 2001 159 165
8. E. Giacobini R. Spiegel A. Enz A.E. Veroff N.R. Cutler J. Neural Transm. 109 2002 1053 1065
9. M.F. Eskander N.G. Nagykery E.Y. Leung B. Khelghati C. Geula Brain Res. 1060 2005 144 152
10. M. Decker F. Krauth J. Lehmann Bioorg. Med. Chem. 14 2006 1966 1977
11. M. Decker J. Med. Chem. 49 2006 5411 5413
12. F. Pasha R. Singh Asian J. Exp. Sci. 19 2005 119 126
13. L. Glusczak D.S. Miron M. Crestani M. Braga da Fonseca F.A. Pedron M.F. Duarte V.L.P. Vieira Ecotoxicol. Environ. Saf. 65 2006 237 241
14. A. Binelli F. Ricciardi C. Riva A. Provini Chemosphere 62 2006 510 519
15. M. Behra C. Etard X. Cousin U. Straehle Toxicol. Sci. 77 2004 325 333
16. K. Fildes L.B. Astheimer P. Story W.A. Buttemer M.J. Hooper Environ. Toxicol. Chem. 25 2006 2964 2970
17. A. Andreani M. Rambaldi A. Leoni A. Locatelli F. Andreani J.-C. Geheret Pharm. Acta Helv. 71 1996 247 252
18. G. Kryger I. Silman J.L. Sussman Structure 7 1999 297 307
19. A. Saxena J.M. Fedorko C.R. Vinayaka R. Medhekar Z. Radić P. Taylor O. Lockridge P. Bhupendra Eur. J. Biochem. 270 2003 4447 4458
20. M. Guardigli P. Pasini M. Mirasoli A. Leoni A. Andreani A. Roda Anal. Chim. Acta 535 2005 139 144
21. A. Andreani A. Cavalli M. Granaiola M. Guardigli A. Leoni A. Locatelli R. Morigi M. Rambaldi M. Recanatini A. Roda J. Med. Chem. 44 2001 4011 4014
22. S. Senapati Y. Cheng J.A. McCammon J. Med. Chem. 49 2006 6222 6230
23. H. Sugimoto H. Ogura Y. Arai Y. Iimura Y. Yamanishi Jpn. J. Pharmacol. 89 2002 7 20