Adaptive evolution of four microcephaly genes and the evolution of brain size in anthropoid primates

Molecular Biology and Evolution

Volumn 28, Issue 1, 2011, Pages 625-638

  Montgomery, Stephen H ^a   Capellini, Isabella ^b   Venditti, Chris ^c   Barton, Robert A ^b   Mundy, Nicholas I ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b DURHAM UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF READING   (United Kingdom)

Author keywords

ASPM; brain; CDK5RAP2; CENPJ; MCPH1; neurogenesis; primates

Indexed keywords

ABNORMAL SPINDLE HOMOLOG PROTEIN; BRAIN PROTEIN; CENTROMERE PROTEIN E; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE 5 REGULATORY SUBUNIT ASSOCIATED PROTEIN 2; MICROCEPHALIN 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN SIZE; BRAIN WEIGHT; CONTROLLED STUDY; EVOLUTIONARY ADAPTATION; GENE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC CONSERVATION; GENETIC LINE; GENETIC LINKAGE; HYPOTHESIS; MICROCEPHALY; MOLECULAR EVOLUTION; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; NONHUMAN; PHYLOGENY; PRIMATE; SIMIAN;

ANIMALS; BIOLOGICAL EVOLUTION; BRAIN; GENOTYPE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICROCEPHALY; MICROTUBULE-ASSOCIATED PROTEINS; NERVE TISSUE PROTEINS; PHENOTYPE; PHYLOGENY; PRIMATES;

PRIMATES; SIMIIFORMES;

EID: 78650485698     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msq237     Document Type: Article

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