Accelerated evolution of the ASPM gene controlling brain size begins prior to human brain expansion

PLoS Biology

Volumn 2, Issue 5, 2004, Pages

  Kouprina, Natalay ^a   Pavlicek, Adam ^b   Mochida, Ganeshwaran H ^c   Solomon, Gregory ^d   Gersch, William ^d   Yoon, Young Ho ^a   Collura, Randall ^e   Ruvolo, Maryellen ^e   Barrett, J Carl ^a   Woods, C Geoffrey ^f   Walsh, Christopher A ^c   Jurka, Jerzy ^b   Larionov, Vladimir ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Genetic Information Research Institute   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^e HARVARD UNIVERSITY   (United States)

^f ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BRAIN CORTEX; BRAIN SIZE; CHIMPANZEE; CLADISTICS; GENE CONTROL; GENE MUTATION; GENE SEQUENCE; GENETIC CODE; GENETIC CONSERVATION; GENOME; GORILLA; HOMINID; HUMAN; INTRON; MOLECULAR CLONING; MOLECULAR EVOLUTION; NONHUMAN; ORANG UTAN; PRIMATE; PROTEIN DOMAIN; PROTEIN FUNCTION; RHESUS MONKEY; ANIMAL; ANTHROPOIDEA; BIOLOGICAL MODEL; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; DNA SEQUENCE; EVOLUTION; EXON; GENE DELETION; GENETIC POLYMORPHISM; GENETIC RECOMBINATION; GENETICS; MACACA; MOLECULAR GENETICS; MOUSE; MUTATION; NUCLEOTIDE SEQUENCE; PAN TROGLODYTES; PHYLOGENY; PHYSIOLOGY; PROMOTER REGION; PROTEIN TERTIARY STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

HOMINIDAE; HOMINOIDEA; MACACA MULATTA; MAMMALIA; PAN TROGLODYTES; PONGO PYGMAEUS; PRIMATES;

ASPM PROTEIN, HUMAN; NERVE PROTEIN; PRIMER DNA;

ANIMALS; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; CONSERVED SEQUENCE; COS CELLS; DNA PRIMERS; EVOLUTION; EVOLUTION, MOLECULAR; EXONS; GENE DELETION; GORILLA GORILLA; HUMANS; INTRONS; MACACA MULATTA; MICE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTATION; NERVE TISSUE PROTEINS; PAN TROGLODYTES; PHYLOGENY; POLYMORPHISM, GENETIC; PONGO PYGMAEUS; PROMOTER REGIONS (GENETICS); PROTEIN STRUCTURE, TERTIARY; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA;

EID: 19344374302     PISSN: 15449173     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pbio.0020126     Document Type: Article

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