-
1
-
-
0035976575
-
Prostaglandins and leukotrienes: Advances in eicosanoid biology
-
Funk CD (2001) Prostaglandins and leukotrienes: Advances in eicosanoid biology. Science 294:1871-1875.
-
(2001)
Science
, vol.294
, pp. 1871-1875
-
-
Funk, C.D.1
-
2
-
-
0020597565
-
Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammation
-
Samuelsson B (1983) Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammation. Science 220:568-575.
-
(1983)
Science
, vol.220
, pp. 568-575
-
-
Samuelsson, B.1
-
3
-
-
0030976460
-
A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis
-
Yokomizo T, Izumi T, Chang K, Takuwa Y, Shimizu T (1997) A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature 387:620-624.
-
(1997)
Nature
, vol.387
, pp. 620-624
-
-
Yokomizo, T.1
Izumi, T.2
Chang, K.3
Takuwa, Y.4
Shimizu, T.5
-
4
-
-
0034618068
-
A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders
-
Yokomizo T, Kato K, Terawaki K, Izumi T, Shimizu T (2000) A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders. J Exp Med 192:421-432.
-
(2000)
J Exp Med
, vol.192
, pp. 421-432
-
-
Yokomizo, T.1
Kato, K.2
Terawaki, K.3
Izumi, T.4
Shimizu, T.5
-
5
-
-
0033600291
-
Characterization of the human cysteinyl leukotriene CysLT1 receptor
-
Lynch KR, et al. (1999) Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature 399:789-793.
-
(1999)
Nature
, vol.399
, pp. 789-793
-
-
Lynch, K.R.1
-
6
-
-
0034730638
-
Characterization of the human cysteinyl leukotriene 2 receptor
-
Heise CE, et al. (2000) Characterization of the human cysteinyl leukotriene 2 receptor. J Biol Chem 275:30531-30536.
-
(2000)
J Biol Chem
, vol.275
, pp. 30531-30536
-
-
Heise, C.E.1
-
8
-
-
0032415706
-
Matrix metalloproteinases and abdominal aortic aneurysms: A potential therapeutic target
-
Sinha S, Frishman WH (1998) Matrix metalloproteinases and abdominal aortic aneurysms: A potential therapeutic target. J Clin Pharmacol 38:1077-1088.
-
(1998)
J Clin Pharmacol
, vol.38
, pp. 1077-1088
-
-
Sinha, S.1
Frishman, W.H.2
-
9
-
-
0036733629
-
Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms
-
Longo GM, et al. (2002) Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms. J Clin Invest 110:625-632.
-
(2002)
J Clin Invest
, vol.110
, pp. 625-632
-
-
Longo, G.M.1
-
10
-
-
70349115558
-
Immune cells and molecular mediators in the pathogenesis of the abdominal aortic aneurysm
-
Rizas KD, Ippagunta N, Tilson MD, 3rd (2009) Immune cells and molecular mediators in the pathogenesis of the abdominal aortic aneurysm. Cardiol Rev 17:201-210.
-
(2009)
Cardiol Rev
, vol.17
, pp. 201-210
-
-
Rizas, K.D.1
Ippagunta, N.2
Tilson III, M.D.3
-
11
-
-
0036840912
-
Involvement of the mural thrombus as a site of protease release and activation in human aortic aneurysms
-
Fontaine V, et al. (2002) Involvement of the mural thrombus as a site of protease release and activation in human aortic aneurysms. Am J Pathol 161:1701-1710.
-
(2002)
Am J Pathol
, vol.161
, pp. 1701-1710
-
-
Fontaine, V.1
-
12
-
-
34248547514
-
Topology of the fibrinolytic system within the mural thrombus of human abdominal aortic aneurysms
-
Houard X, et al. (2007) Topology of the fibrinolytic system within the mural thrombus of human abdominal aortic aneurysms. J Pathol 212:20-28.
-
(2007)
J Pathol
, vol.212
, pp. 20-28
-
-
Houard, X.1
-
13
-
-
33847110122
-
The pro-inflammatory and chemotactic cytokine microenvironment of the abdominal aortic aneurysm wall: A protein array study
-
Middleton RK, et al. (2007) The pro-inflammatory and chemotactic cytokine microenvironment of the abdominal aortic aneurysm wall: a protein array study. J Vasc Surg 45:574-580.
-
(2007)
J Vasc Surg
, vol.45
, pp. 574-580
-
-
Middleton, R.K.1
-
14
-
-
70349303279
-
Differential inflammatory activity across human abdominal aortic aneurysms reveals neutrophil-derived leukotriene B4 as a major chemotactic factor released from the intraluminal thrombus
-
Houard X, Ollivier V, Louedec L, Michel JB, Bäck M (2009) Differential inflammatory activity across human abdominal aortic aneurysms reveals neutrophil-derived leukotriene B4 as a major chemotactic factor released from the intraluminal thrombus. FASEB J 23:1376-1383.
-
(2009)
FASEB J
, vol.23
, pp. 1376-1383
-
-
Houard, X.1
Ollivier, V.2
Louedec, L.3
Michel, J.B.4
Bäck, M.5
-
15
-
-
0345599885
-
Influence of intraluminal thrombus on structural and cellular composition of abdominal aortic aneurysm wall
-
Kazi M, et al. (2003) Influence of intraluminal thrombus on structural and cellular composition of abdominal aortic aneurysm wall. J Vasc Surg 38:1283-1292.
-
(2003)
J Vasc Surg
, vol.38
, pp. 1283-1292
-
-
Kazi, M.1
-
16
-
-
23844530173
-
Leukotriene modifiers as potential therapeutics for cardiovascular disease
-
Funk CD (2005) Leukotriene modifiers as potential therapeutics for cardiovascular disease. Nat Rev Drug Discov 4:664-672.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 664-672
-
-
Funk, C.D.1
-
17
-
-
33744497551
-
Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability
-
Qiu H, et al. (2006) Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability. Proc Natl Acad Sci USA 103:8161-8166.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 8161-8166
-
-
Qiu, H.1
-
18
-
-
10744220794
-
The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke
-
Helgadottir A, et al. (2004) The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nat Genet 36:233-239.
-
(2004)
Nat Genet
, vol.36
, pp. 233-239
-
-
Helgadottir, A.1
-
19
-
-
4644301666
-
The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia- Dependent aortic aneurysm
-
Zhao L, et al. (2004) The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia- dependent aortic aneurysm. Nat Med 10:966-973.
-
(2004)
Nat Med
, vol.10
, pp. 966-973
-
-
Zhao, L.1
-
20
-
-
34250835541
-
Inhibited aortic aneurysm formation in BLT1-deficient mice
-
Ahluwalia N, et al. (2007) Inhibited aortic aneurysm formation in BLT1-deficient mice. J Immunol 179:691-697.
-
(2007)
J Immunol
, vol.179
, pp. 691-697
-
-
Ahluwalia, N.1
-
21
-
-
34447538179
-
Angiotensin II-induced abdominal aortic aneurysm occurs independently of the 5-lipoxygenase pathway in apolipoprotein E-deficient mice
-
Cao RY, Adams MA, Habenicht AJ, Funk CD (2007) Angiotensin II-induced abdominal aortic aneurysm occurs independently of the 5-lipoxygenase pathway in apolipoprotein E-deficient mice. Prostaglandins Other Lipid Mediat 84:34-42.
-
(2007)
Prostaglandins Other Lipid Mediat
, vol.84
, pp. 34-42
-
-
Cao, R.Y.1
Adams, M.A.2
Habenicht, A.J.3
Funk, C.D.4
-
22
-
-
77953873545
-
Architecture of intraluminal thrombus removed from abdominal aortic aneurysm
-
Matusik P, et al. (2010) Architecture of intraluminal thrombus removed from abdominal aortic aneurysm. J Thromb Thrombolysis 30:7-9.
-
(2010)
J Thromb Thrombolysis
, vol.30
, pp. 7-9
-
-
Matusik, P.1
-
23
-
-
34047231902
-
Cysteinyl leukotrienes enhance tumour necrosis factor-alphainduced matrix metalloproteinase-9 in human monocytes/macrophages
-
Ichiyama T, et al. (2007) Cysteinyl leukotrienes enhance tumour necrosis factor-alphainduced matrix metalloproteinase-9 in human monocytes/macrophages. Clin Exp Allergy 37:608-614.
-
(2007)
Clin Exp Allergy
, vol.37
, pp. 608-614
-
-
Ichiyama, T.1
-
24
-
-
0033590513
-
Treatment of asthma with drugs modifying the leukotriene pathway
-
Drazen JM, Israel E, O'Byrne PM (1999) Treatment of asthma with drugs modifying the leukotriene pathway. N Engl J Med 340:197-206.
-
(1999)
N Engl J Med
, vol.340
, pp. 197-206
-
-
Drazen, J.M.1
Israel, E.2
O'Byrne, P.M.3
-
25
-
-
38749113897
-
What's all the FLAP about?: 5-lipoxygenase-activating protein inhibitors for inflammatory diseases
-
Evans JF, Ferguson AD, Mosley RT, Hutchinson JH (2008) What's all the FLAP about?: 5-lipoxygenase-activating protein inhibitors for inflammatory diseases. Trends Pharmacol Sci 29:72-78.
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 72-78
-
-
Evans, J.F.1
Ferguson, A.D.2
Mosley, R.T.3
Hutchinson, J.H.4
-
26
-
-
34547902858
-
Presence of NGAL/MMP-9 complexes in human abdominal aortic aneurysms
-
Folkesson M, et al. (2007) Presence of NGAL/MMP-9 complexes in human abdominal aortic aneurysms. Thromb Haemost 98:427-433.
-
(2007)
Thromb Haemost
, vol.98
, pp. 427-433
-
-
Folkesson, M.1
-
27
-
-
77952424069
-
Pharmacological inhibition of BLT1 diminishes early abdominal aneurysm formation
-
Kristo F, et al. (2010) Pharmacological inhibition of BLT1 diminishes early abdominal aneurysm formation. Atherosclerosis 210:107-113.
-
(2010)
Atherosclerosis
, vol.210
, pp. 107-113
-
-
Kristo, F.1
-
28
-
-
34447626440
-
Is there a role for the macrophage 5- lipoxygenase pathway in aortic aneurysm development in apolipoprotein E-deficient mice?
-
Funk CD, Cao RY, Zhao L, Habenicht AJ (2006) Is there a role for the macrophage 5- lipoxygenase pathway in aortic aneurysm development in apolipoprotein E-deficient mice? Ann N Y Acad Sci 1085:151-160.
-
(2006)
Ann N Y Acad Sci
, vol.1085
, pp. 151-160
-
-
Funk, C.D.1
Cao, R.Y.2
Zhao, L.3
Habenicht, A.J.4
-
30
-
-
0037018105
-
Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonists
-
Mellor EA, Austen KF, Boyce JA (2002) Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonists. J Exp Med 195: 583-592.
-
(2002)
J Exp Med
, vol.195
, pp. 583-592
-
-
Mellor, E.A.1
Austen, K.F.2
Boyce, J.A.3
-
31
-
-
33644815051
-
Cysteinyl leukotrienes induce monocyte chemoattractant protein 1 in human monocytes/macrophages
-
Ichiyama T, et al. (2005) Cysteinyl leukotrienes induce monocyte chemoattractant protein 1 in human monocytes/macrophages. Clin Exp Allergy 35:1214-1219.
-
(2005)
Clin Exp Allergy
, vol.35
, pp. 1214-1219
-
-
Ichiyama, T.1
-
32
-
-
51849091383
-
Cysteinyl leukotrienes induce macrophage inflammatory protein-1 in human monocytes/macrophages
-
Ichiyama T, et al. (2009) Cysteinyl leukotrienes induce macrophage inflammatory protein-1 in human monocytes/macrophages. Int Arch Allergy Immunol 148:147-153.
-
(2009)
Int Arch Allergy Immunol
, vol.148
, pp. 147-153
-
-
Ichiyama, T.1
-
33
-
-
34247847681
-
Resolution phase of inflammation: Novel endogenous antiinflammatory and proresolving lipid mediators and pathways
-
Serhan CN (2007) Resolution phase of inflammation: novel endogenous antiinflammatory and proresolving lipid mediators and pathways. Annu Rev Immunol 25: 101-137.
-
(2007)
Annu Rev Immunol
, vol.25
, pp. 101-137
-
-
Serhan, C.N.1
-
34
-
-
77952313992
-
Leukotriene A(4) hydrolase inhibition attenuates allergic airway inflammation and hyperresponsiveness
-
Rao NL, et al. (2010) Leukotriene A(4) hydrolase inhibition attenuates allergic airway inflammation and hyperresponsiveness. Am J Respir Crit Care Med 181:899-907.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 899-907
-
-
Rao, N.L.1
-
35
-
-
55949121449
-
Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors
-
Maekawa A, Kanaoka Y, Xing W, Austen KF (2008) Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors. Proc Natl Acad Sci USA 105:16695-16700.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 16695-16700
-
-
Maekawa, A.1
Kanaoka, Y.2
Xing, W.3
Austen, K.F.4
-
36
-
-
70449700139
-
Leukotriene E4-induced pulmonary inflammation is mediated by the P2Y12 receptor
-
Paruchuri S, et al. (2009) Leukotriene E4-induced pulmonary inflammation is mediated by the P2Y12 receptor. J Exp Med 206:2543-2555.
-
(2009)
J Exp Med
, vol.206
, pp. 2543-2555
-
-
Paruchuri, S.1
-
37
-
-
67650930912
-
GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4
-
Maekawa A, Balestrieri B, Austen KF, Kanaoka Y (2009) GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4. Proc Natl Acad Sci USA 106:11685-11690.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 11685-11690
-
-
Maekawa, A.1
Balestrieri, B.2
Austen, K.F.3
Kanaoka, Y.4
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