RhoA/Rho kinase pathway contributes to the pathogenesis of thermal hyperalgesia in diabetic mice

Pain

Volumn 152, Issue 1, 2011, Pages 114-122

  Ohsawa, Masahiro ^a   Aasato, Megumi ^a   Hayashi, Shun Suke ^a   Kamei, Junzo ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Diabetes; eNOS; HMG CoA reductase inhibitor; Hyperalgesia; RhoA; Spinal cord

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EXOENZYME C3; MEVALONIC ACID; MEVALONOLACTONE; NITRIC OXIDE; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SIMVASTATIN; STREPTOZOCIN;

ALLODYNIA; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; CELLULAR DISTRIBUTION; CLOSTRIDIUM BOTULINUM; CONTROL GROUP; CONTROLLED STUDY; DIABETIC NEUROPATHY; DRUG INHIBITION; HYPERALGESIA; MALE; MECHANICAL ALLODYNIA; MOUSE; NONHUMAN; PAIN THRESHOLD; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPINAL CORD; STREPTOZOCIN DIABETES; TAIL FLICK TEST; THERMAL HYPERALGESIA; WESTERN BLOTTING;

AMIDES; ANIMALS; COMPLEMENT C3; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERALGESIA; MALE; MICE; MICE, INBRED ICR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PAIN THRESHOLD; PYRIDINES; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; SIMVASTATIN; SPINAL CORD; STREPTOZOCIN; TIME FACTORS;

EID: 78650414867     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2010.10.005     Document Type: Article

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