HMG-CoA reductase inhibitor ameliorates diabetic nephropathy by its pleiotropic effects in rats

Nephrology Dialysis Transplantation

Volumn 18, Issue 2, 2003, Pages 265-272

  Usui, Hitomi ^a   Shikata, Kenichi ^a   Matsuda, Mitsuhiro ^a   Okada, Shinichi ^a   Ogawa, Daisuke ^a   Yamashita, Tetsuji ^a   Hida, Kazuyuki ^a   Satoh, Minoru ^a   Wada, Jun ^a   Makino, Hirofumi ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Diabetic nephropathy; HMG CoA reductase inhibitor; ICAM 1; Macrophage; NF B; Oxidative stress

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALBUMIN; CERIVASTATIN; DRUG VEHICLE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DOSE RESPONSE; DRUG EFFECT; GEL MOBILITY SHIFT ASSAY; GLOMERULAR STRUCTURE; HYPOTHESIS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KIDNEY INJURY; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; MACROPHAGE; MALE; NONHUMAN; OXIDATIVE STRESS; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STREPTOZOCIN DIABETES; UPREGULATION; URINARY EXCRETION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL MOVEMENT; DEOXYGUANOSINE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INTERCELLULAR ADHESION MOLECULE-1; KIDNEY; KIDNEY GLOMERULUS; MACROPHAGES; MALE; NF-KAPPA B; OXIDATIVE STRESS; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

EID: 0037315103     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/18.2.265     Document Type: Article

References (20)

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