PD-1-PD-L1 pathway impairs Th1 immune response in the late stage of infection with Mycobacterium bovis bacillus Calmette-Guérin

International Immunology

Volumn 22, Issue 12, 2010, Pages 915-925

  Sakai, Shunsuke ^a   Kawamura, Ikuo ^a   Okazaki, Taku ^b   Tsuchiya, Kohsuke ^a   Uchiyama, Ryousuke ^c   Mitsuyama, Masao ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

Mycobacterium; PD 1; Persistent infection; Th1 immunity

Indexed keywords

BCG VACCINE; CD28 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; INTERLEUKIN 10; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; BOVINE TUBERCULOSIS; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; IMMUNOSTIMULATION; LUNG; MACROPHAGE; MOUSE; MYCOBACTERIUM BOVIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN; TH1 CELL; UPREGULATION; WILD TYPE;

ANIMALS; ANTIGENS, CD80; ANTIGENS, DIFFERENTIATION; BCG VACCINE; HOST-PATHOGEN INTERACTIONS; INTERFERON-GAMMA; LUNG; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYCOBACTERIUM BOVIS; PEPTIDES; SPLEEN; TH1 CELLS; TIME FACTORS; TUBERCULOSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 78650369297     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxq446     Document Type: Article

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