Inactivation of CD4+CD25+ regulatory T cells during early mycobacterial infection increases cytokine production but does not affect pathogen load

Immunology and Cell Biology

Volumn 84, Issue 5, 2006, Pages 467-474

  Quinn, Kylie M ^a   McHugh, Rebecca S ^a   Rich, Fenella J ^a   Goldsack, Lisa M ^a   De Lisle, Geoffrey W ^b   Buddle, Bryce M ^b   Delahunt, Brett ^c   Kirman, Joanna R ^a  

^a MALAGHAN INSTITUTE OF MEDICAL RESEARCH   (New Zealand)

^b AGRESEARCH   (New Zealand)

^c UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Mycobacterium; Regulatory T cell; Tuberculosis

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY PC 61; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CD4+ CD25+ T LYMPHOCYTE; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; FLOW CYTOMETRY; IMMUNE RESPONSE; IN VIVO STUDY; LUNG; LUNG TUBERCULOSIS; MOUSE; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATHOGENESIS; SPLEEN;

ACUTE-PHASE REACTION; ANIMALS; ANTIBODIES, MONOCLONAL; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; INTERFERON TYPE II; INTERLEUKIN-2; MICE; MICE, INBRED C57BL; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; RECEPTORS, INTERLEUKIN-2; T-LYMPHOCYTES, REGULATORY; TUBERCULOSIS, PULMONARY;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS;

EID: 33747840296     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1111/j.1440-1711.2006.01460.x     Document Type: Article

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