Anaphylatoxin C5a-induced toll-like receptor 4 signaling in bovine neutrophils

Journal of Dairy Science

Volumn 94, Issue 1, 2011, Pages 152-164

  Stevens, M G H ^a   Van Poucke, M ^a   Peelman, L J ^b   Rainard, P ^a   De Spiegeleer, B ^a   Rogiers, C ^a   Van de Walle, G R ^a   Duchateau, L ^a   Burvenich, C ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UR1282   (France)

Author keywords

Complement component 5a; Neutrophil; Sepsis; Toll like receptor 4

Indexed keywords

CD14 ANTIGEN; COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; INTERLEUKIN 8; MESSENGER RNA; TOLL LIKE RECEPTOR 4;

ANIMAL; ANIMAL DISEASE; ARTICLE; CATTLE; CATTLE DISEASE; DRUG EFFECT; GENE EXPRESSION; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; NEUTROPHIL; PHYSIOLOGY; SEPSIS; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD14; CATTLE; CATTLE DISEASES; COMPLEMENT C5A; GENE EXPRESSION; IMMUNITY, INNATE; INTERLEUKIN-8; NEUTROPHILS; RECEPTOR, ANAPHYLATOXIN C5A; RNA, MESSENGER; SEPSIS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

BOVINAE;

EID: 78650332477     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2010-3358     Document Type: Article

References (46)

1. Akira S., Hoshino K. Myeloid differentiation factor 88-dependent and independent pathways in toll-like receptor signaling. J. Infect. Dis. 2003, 187(Suppl. 2):S356-S363.
2. Bamberg C.E., Mackay C.R., Lee H., Zahra D., Jackson J., Lim Y.S., Whitfeld P.L., Craig S., Corsini E., Lu B., Gerard C., Gerard N.P. The C5a receptor C5L2 is a negative modulator of C5aR mediated signal transduction. J. Biol. Chem. 2010, 285:7633-7644.
3. Bazzoni F., Cassatella M.A., Laudanna C., Rossi F. Phagocytosis of opsonized yeast induces tumor necrosis factor-alpha mRNA accumulation and protein release by human polymorphonuclear leukocytes. J. Leukoc. Biol. 1991, 50:223-228.
4. Beutler B., Du X., Poltorak A. Identification of toll-like receptor 4 (TLR4) as the sole conduit for LPS signal transduction: Genetic and evolutionary studies. J. Endotoxin Res. 2001, 7:277-280.
5. Burvenich C., Van Merris V., Mehrzad J., Diez-Fraile A., Duchateau L. Severity of E. coli mastitis is mainly determined by cow factors. Vet. Res. 2003, 34:521-564.
6. Cassatella M.A., Bazzoni F., Ceska M., Ferro I., Baggiolini M., Berton G. IL-8 production by human polymorphonuclear leukocytes. The chemoattractant formyl-methionyl-leucyl-phenylalanine induces the gene expression and release of IL-8 through a pertussis toxin-sensitive pathway. J. Immunol. 1992, 148:3216-3220.
7. Chaudhary A., Fresquez T.M., Naranjo M.J. Tyrosine kinase Syk associates with toll-like receptor 4 and regulates signaling in human monocytic cells. Immunol. Cell Biol. 2007, 85:249-256.
8. Chen L.F., Williams S.A., Mu Y., Nakano H., Duerr J.M., Buckbinder L., Greene W.C. NF-kappaB RELA phosphorylation regulates RELA acetylation. Mol. Cell. Biol. 2005, 25:7966-7975.
9. Chuang T.H., Ulevitch R.J. Triad3A, an E3 ubiquitin-protein ligase regulating toll-like receptors. Nat. Immunol. 2004, 5:495-502.
10. De Ketelaere A., Goossens K., Peelman L., Burvenich C. Validation of internal control genes for gene expression analysis in bovine polymorphonuclear leucocytes. J. Dairy Sci. 2006, 89:4066-4069.
11. Ember J.A., Sanderson S.D., Hugli T.E., Morgan E.L. Induction of interleukin-8 synthesis from monocytes by human C5a anaphylatoxin. Am. J. Pathol. 1994, 144:393-403.
12. Fitzgerald K.A., Rowe D.C., Golenbock D.T. Endotoxin recognition and signal transduction by the TLR4/MD2-complex. Microbes Infect. 2004, 6:1361-1367.
13. Gennaro R., Simonic T., Negri A., Mottola C., Secchi C., Ronchi S., Romeo D. C5a fragment of bovine complement. Purification, bioassays, amino-acid sequence and other structural studies. Eur. J. Biochem. 1986, 155:77-86.
14. Gilchrist M., Thorsson V., Li B., Rust A.G., Korb M., Roach J.C., Kennedy K., Hai T., Bolouri H., Aderem A. Systems biology approaches identify ATF3 as a negative regulator of toll-like receptor 4. Nature 2006, 441:173-178.
15. Goossens K., Van Poucke M., Van Soom A., Vandesompele J., Van Zeveren A., Peelman L.J. Selection of reference genes for quantitative real-time PCR in bovine preimplantation embryos. BMC Dev. Biol. 2005, 5:27.
16. Guo R.F., Riedemann N.C., Bernacki K.D., Sarma V.J., Laudes I.J., Reuben J.S., Younkin E.M., Neff T.A., Paulauskis J.D., Zetoune F.S., Ward P.A. Neutrophil C5a receptor and the outcome in a rat model of sepsis. FASEB J. 2003, 17:1889-1891.
17. Guo R.F., Riedemann N.C., Ward P.A. Role of C5a-C5aR interaction in sepsis. Shock 2004, 21:1-7.
18. Guo R.F., Ward P.A. Role of C5a in inflammatory responses. Annu. Rev. Immunol. 2005, 23:821-852.
19. Hawlisch H., Belkaid Y., Baelder R., Hildeman D., Gerard C., Köhl J. C5a negatively regulates toll-like receptor 4-induced immune responses. Immunity 2005, 22:415-426.
20. Hsu M.H., Wang M., Browning D.D., Mukaida N., Ye R.D. NF-kappaB activation is required for C5a-induced interleukin-8 gene expression in mononuclear cells. Blood 1999, 93:3241-3249.
21. Jack R.S., Fan X., Bernheiden M., Rune G., Ehlers M., Weber A., Kirsch G., Mentel R., Fürll B., Freudenberg M., Schmitz G., Stelter F., Schütt C. Lipopolysaccharide-binding protein is required to combat a murine gram-negative bacterial infection. Nature 1997, 389:742-745.
22. Lang T., Mansell A. The negative regulation of Toll-like receptor and associated pathways. Immunol. Cell Biol. 2007, 85:425-434.
23. Lloyd K.L., Kubes P. GPI-linked endothelial CD14 contributes to the detection of LPS. Am. J. Physiol. Heart Circ. Physiol. 2006, 291:H473-H481.
24. Lord P.C., Wilmoth L.M., Mizel S.B., McCall C.E. Expression of interleukin-1 alpha and beta genes by human blood polymorphonuclear leukocytes. J. Clin. Invest. 1991, 87:1312-1321.
25. Marchant A., Tielemans C., Husson C., Gastaldello K., Schurmans T., De Groote D., Duchow J., Vanherweghem L., Goldman M. Cuprophane haemodialysis induces upregulation of LPS receptor (CD14) on monocytes: Role of complement activation. Nephrol. Dial. Transplant. 1996, 11:657-662.
26. McDonald P.P., Bald A., Cassatella M.A. Activation of the NF-kappaB pathway by inflammatory stimuli in human neutrophils. Blood 1997, 89:3421-3433.
27. Nemali S., Siemsen D.W., Nelson L.K., Bunger P.L., Faulkner C.L., Rainard P., Gauss K.A., Jutila M.A., Quinn M.T. Molecular analysis of the bovine anaphylatoxin C5a receptor. J. Leukoc. Biol. 2008, 84:537-549.
28. Pearl-Yafe M., Fabian I., Halperin D., Flatau E., Werber S., Shalit I. Interferon-gamma and bacterial lipopolysaccharide act synergistically on human neutrophils enhancing interleukin-8, interleukin-1beta, tumor necrosis factor-alpha, and interleukin-12 p70 secretion and phagocytosis via upregulation of toll-like receptor 4. Shock 2007, 27:226-231.
29. Rainard P. The complement in milk and defense of the bovine mammary gland against infections. Vet. Res. 2003, 34:647-670.
30. Riedemann N.C., Guo R.F., Ward P.A. A key role of C5a/C5aR activation for the development of sepsis. J. Leukoc. Biol. 2003, 74:966-970.
31. Sada K., Takano T., Yanagi S., Yamamura H. Structure and function of Syk protein-tyrosine kinase. J. Biochem. 2001, 130:177-186.
32. Sears P.M., Paape M.J., Pearson R.E., Gwazdauskas F.C. Comparison between tail vein and jugular vein cannulation in cattle. J. Dairy Sci. 1978, 61:974-979.
33. Sendide K., Reiner N.E., Lee J.S., Bourgoin S., Talal A., Hmama Z. Cross-talk between CD14 and complement receptor 3 promotes phagocytosis of mycobacteria: Regulation by phosphatidylinositol 3-kinase and cytohesin-1. J. Immunol. 2005, 174:4210-4219.
34. Shuster D.E., Kehrli M.E., Rainard P., Paape M. Complement fragment C5a and inflammatory cytokines in neutrophil recruitment during intramammary infection with Escherichia coli. Infect. Immun. 1997, 65:3286-3292.
35. Siemens D.W., Schepetkin I.A., Kirpotina L.N., Lei B., Quinn M.T. Neutrophil isolation from nonhuman species. Methods Mol. Biol. 2007, 138:21-34.
36. Stevens M.G.H., Peelman L., De Spiegeleer B., Pezeshki A., Van De Walle G.R., Duchateau L., Burvenich C. Differential gene expression of the TLR4 cascade and neutrophil function in early and mid-lactating dairy cows. J. Dairy Sci. 2011, 10.3168/jds.2010-3563.
37. Strieter R.M., Kasahara K., Allen R.M., Standiford T.J., Rolfe M.W., Becker F.S., Chensue S.W., Kunkel S.L. Cytokine-induced neutrophil-derived interleukin-8. Am. J. Pathol. 1992, 141:397-407.
38. Tak P.P., Firestein G.S. NF-kappaB: A key role in inflammatory diseases. J. Clin. Invest. 2001, 107:7-11.
39. van Bruggen R., Zweers D., van Diepen A., van Dissel J.T., Roos D., Verhoeven A.J., Kuijpers T.W. Complement receptor 3 and Toll-like receptor 4 act sequentially in uptake and intracellular killing of unopsonized Salmonella enterica serovar Typhimurium by human neutrophils. Infect. Immun. 2007, 75:2655-2660.
40. Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002, doi:10.1186/gb-2002-3-7-research0034.
41. Ward P.A. The dark side of C5a in sepsis. Nat. Rev. Immunol. 2004, 4:133-142.
42. Ward P.A. Functions of C5a receptors. J. Mol. Med. 2009, 87:375-378.
43. Weingarten R., Sklar L.A., Mathison J.C., Omidi S., Ainsworth T., Simon S., Ulevitch R.J., Tobias P.S. Interactions of lipopolysaccharide with neutrophils in blood via CD14. J. Leukoc. Biol. 1993, 53:518-524.
44. Xia Z.P., Sun L., Chen X., Pineda G., Jiang X., Adhikari A., Zeng W., Chen Z.J. Direct activation of protein kinases by unanchored polyubiquitin chains. Nature 2009, 461:114-119.
45. Zarewych D.M., Kindzelskii A.L., Todd R.F., Petty H.R. LPS induces CD14 association with complement receptor type 3, which is reversed by neutrophil adhesion. J. Immunol. 1996, 156:430-433.
46. Zhong H., Voll R.E., Ghosh S. Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol. Cell 1998, 1:661-671.