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Volumn 36, Issue 1, 2009, Pages 153-158

Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma

Author keywords

Human osteosarcoma; Osteoblast; p53 p21 pathway; pRB gene; Runx2

Indexed keywords

TRANSCRIPTION FACTOR RUNX2;

EID: 56649109716     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-008-9378-1     Document Type: Article
Times cited : (51)

References (22)
  • 3
    • 18344372018 scopus 로고    scopus 로고
    • The RUNX genes: Gain or loss of function in cancer
    • 10.1038/nrc1607
    • K Blyth ER Cameron JC Neil 2005 The RUNX genes: gain or loss of function in cancer Nat Rev Cancer 5 376 387 10.1038/nrc1607
    • (2005) Nat Rev Cancer , vol.5 , pp. 376-387
    • Blyth, K.1    Cameron, E.R.2    Neil, J.C.3
  • 4
    • 33846882630 scopus 로고    scopus 로고
    • Molecular pathogenesis of osteosarcoma
    • 10.1089/dna.2006.0505
    • M Kansara DM Thomas 2007 Molecular pathogenesis of osteosarcoma DNA Cell Biol 26 1 18 10.1089/dna.2006.0505
    • (2007) DNA Cell Biol , vol.26 , pp. 1-18
    • Kansara, M.1    Thomas, D.M.2
  • 5
    • 25444473106 scopus 로고    scopus 로고
    • The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion
    • 10.1128/MCB.25.19.8581-8591.2005
    • J Pratap A Javed LR Languino AJ van Wijnen JL Stein GS Stein JB Lian 2005 The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion Mol Cell Biol 25 8581 8591 10.1128/MCB.25.19.8581-8591.2005
    • (2005) Mol Cell Biol , vol.25 , pp. 8581-8591
    • Pratap, J.1    Javed, A.2    Languino, L.R.3    Van Wijnen, A.J.4    Stein, J.L.5    Stein, G.S.6    Lian, J.B.7
  • 7
    • 0034840594 scopus 로고    scopus 로고
    • The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation
    • 10.1016/S1097-2765(01)00327-6
    • DM Thomas SA Carty DM Piscopo JS Lee WF Wang WC Forrester PW Hinds 2001 The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation Mol Cell 8 303 316 10.1016/S1097-2765(01)00327-6
    • (2001) Mol Cell , vol.8 , pp. 303-316
    • Thomas, D.M.1    Carty, S.A.2    Piscopo, D.M.3    Lee, J.S.4    Wang, W.F.5    Forrester, W.C.6    Hinds, P.W.7
  • 8
    • 0041767354 scopus 로고    scopus 로고
    • Tumor suppressor pRB functions as a co-repressor of the CCAAT displacement protein (CDP/cut) to regulate cell cycle controlled histone H4 transcription
    • 10.1002/jcp.10335
    • S Gupta MX Luong SA Bleuming A Miele M Luong D Young ES Knudsen AJ Van Wijnen JL Stein GS Stein 2003 Tumor suppressor pRB functions as a co-repressor of the CCAAT displacement protein (CDP/cut) to regulate cell cycle controlled histone H4 transcription J Cell Physiol 196 541 556 10.1002/jcp.10335
    • (2003) J Cell Physiol , vol.196 , pp. 541-556
    • Gupta, S.1    Luong, M.X.2    Bleuming, S.A.3    Miele, A.4    Luong, M.5    Young, D.6    Knudsen, E.S.7    Van Wijnen, A.J.8    Stein, J.L.9    Stein, G.S.10
  • 9
    • 0032578407 scopus 로고    scopus 로고
    • PRB plays an essential role in cell cycle arrest induced by DNA damage
    • 10.1073/pnas.95.20.11945
    • EA Harrington JL Bruce E Harlow N Dyson 1998 pRB plays an essential role in cell cycle arrest induced by DNA damage Proc Natl Acad Sci USA 95 11945 11950 10.1073/pnas.95.20.11945
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 11945-11950
    • Harrington, E.A.1    Bruce, J.L.2    Harlow, E.3    Dyson, N.4
  • 11
    • 0036232986 scopus 로고    scopus 로고
    • Etiology of osteosarcoma
    • 10.1097/00003086-200204000-00007
    • B Fuchs DJ Pritchard 2002 Etiology of osteosarcoma Clin Orthop Relat Res 397 40 52 10.1097/00003086-200204000-00007
    • (2002) Clin Orthop Relat Res , vol.397 , pp. 40-52
    • Fuchs, B.1    Pritchard, D.J.2
  • 12
    • 20144371011 scopus 로고    scopus 로고
    • The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts
    • 10.1074/jbc.M413665200
    • M Galindo J Pratap DW Young H Hovhannisyan HJ Im JY Choi JB Lian JL Stein GS Stein AJ van Wijnen 2005 The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts J Biol Chem 280 20274 20285 10.1074/jbc.M413665200
    • (2005) J Biol Chem , vol.280 , pp. 20274-20285
    • Galindo, M.1    Pratap, J.2    Young, D.W.3    Hovhannisyan, H.4    Im, H.J.5    Choi, J.Y.6    Lian, J.B.7    Stein, J.L.8    Stein, G.S.9    Van Wijnen, A.J.10
  • 15
    • 33646350024 scopus 로고    scopus 로고
    • Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation
    • 10.1074/jbc.M508162200
    • M Qiao P Shapiro M Fosbrink H Rus R Kumar A Passaniti 2006 Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation J Biol Chem 281 7118 7128 10.1074/jbc.M508162200
    • (2006) J Biol Chem , vol.281 , pp. 7118-7128
    • Qiao, M.1    Shapiro, P.2    Fosbrink, M.3    Rus, H.4    Kumar, R.5    Passaniti, A.6
  • 16
    • 33745184891 scopus 로고    scopus 로고
    • Cyclin D1-cdk4 induces runx2 ubiquitination and degradation
    • 10.1074/jbc.M603439200
    • R Shen X Wang H Drissi F Liu RJ O'Keefe D Chen 2006 Cyclin D1-cdk4 induces runx2 ubiquitination and degradation J Biol Chem 281 16347 16353 10.1074/jbc.M603439200
    • (2006) J Biol Chem , vol.281 , pp. 16347-16353
    • Shen, R.1    Wang, X.2    Drissi, H.3    Liu, F.4    O'Keefe, R.J.5    Chen, D.6
  • 17
    • 0038499524 scopus 로고    scopus 로고
    • A new method for determining the status of p53 in tumor cell lines of different origin
    • AL Gartel C Feliciano AL Tyner 2003 A new method for determining the status of p53 in tumor cell lines of different origin Oncol Res 13 405 408
    • (2003) Oncol Res , vol.13 , pp. 405-408
    • Gartel, A.L.1    Feliciano, C.2    Tyner, A.L.3
  • 18
    • 33748275681 scopus 로고    scopus 로고
    • The p53 tumor suppressor participates in multiple cell cycle checkpoints
    • 10.1002/jcp.20689
    • LE Giono JJ Manfredi 2006 The p53 tumor suppressor participates in multiple cell cycle checkpoints J Cell Physiol 209 13 20 10.1002/jcp.20689
    • (2006) J Cell Physiol , vol.209 , pp. 13-20
    • Giono, L.E.1    Manfredi, J.J.2
  • 19
    • 0029802591 scopus 로고    scopus 로고
    • P53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
    • 10.1101/gad.10.19.2438
    • X Chen LJ Ko L Jayaraman C Prives 1996 p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells Genes Dev 10 2438 2451 10.1101/gad.10.19.2438
    • (1996) Genes Dev , vol.10 , pp. 2438-2451
    • Chen, X.1    Ko, L.J.2    Jayaraman, L.3    Prives, C.4
  • 21
    • 29944437296 scopus 로고    scopus 로고
    • P53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling
    • 1. 10.1083/jcb.200507106
    • X Wang HY Kua Y Hu K Guo Q Zeng Q Wu HH Ng G Karsenty B de Crombrugghe J Yeh B Li 2006 p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling J Cell Biol 172 1 115 125 10.1083/jcb.200507106
    • (2006) J Cell Biol , vol.172 , pp. 115-125
    • Wang, X.1    Kua, H.Y.2    Hu, Y.3    Guo, K.4    Zeng, Q.5    Wu, Q.6    Ng, H.H.7    Karsenty, G.8    De Crombrugghe, B.9    Yeh, J.10    Li, B.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.