Cetacean Toll-like receptor 4 and myeloid differentiation factor 2, and possible cetacean-specific responses against Gram-negative bacteria

Comparative Immunology, Microbiology and Infectious Diseases

Volumn 33, Issue 6, 2010, Pages

  Shishido, Reiko ^a,b   Ohishi, Kazue ^a   Suzuki, Rintaro ^c   Takishita, Kiyotaka ^a   Ohtsu, Dai ^d   Okutsu, Kenji ^d   Tokutake, Koji ^d   Katsumata, Etsuko ^e   Bando, Takeharu ^f   Fujise, Yoshihiro ^f   Murayama, Tsukasa ^g   Maruyama, Tadashi ^a,b  

^a JAPAN AGENCY FOR MARINE EARTH SCIENCE AND TECHNOLOGY   (Japan)

^b TOKYO UNIVERSITY OF MARINE SCIENCE AND TECHNOLOGY   (Japan)

^c NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

^d Yokohama Hakkeijima Sea Paradise   (Japan)

^e Kamogawa Sea World   (Japan)

^f T   (Japan)

^g TOKAI UNIVERSITY   (Japan)

Author keywords

Cetacean; Dolphin; Innate immunity; Lipopolysaccharide; Myeloid differentiation factor 2; Toll like receptor 4; Whale

Indexed keywords

BINDING PROTEIN; COMPLEMENTARY DNA; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BETA SHEET; CETACEA; COMPLEX FORMATION; DNA SEQUENCE; GRAM NEGATIVE BACTERIUM; INNATE IMMUNITY; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SPECIES DIFFERENCE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; DOLPHINS; GRAM-NEGATIVE BACTERIA; LIPOPOLYSACCHARIDES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHYLOGENY; POLYMERASE CHAIN REACTION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; SPECIES SPECIFICITY; TOLL-LIKE RECEPTOR 4; WHALE, KILLER;

CETACEA; MAMMALIA; NEGIBACTERIA;

EID: 78650203715     PISSN: 01479571     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cimid.2010.03.003     Document Type: Article

References (29)

1. Foster G., MacMillan A.P., Godfroid J., Howie F., Ross H.M., Cloeckaert A., et al. A review of Brucella sp. infection of sea mammals with particular emphasis on isolates from Scotland. Vet Microbiol 2002, 90:563-580.
2. Ohishi K., Fujise Y., Maruyama T. Brucella spp. in the western North Pacific and Antarctic cetaceans. J Cet Res Man 2008, 10:67-72.
3. Lemaitre B., Nicolas E., Michaut L., Reichhart J., Hoffmann J. The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 1996, 86:973-983.
4. Medzhitov R., Preston-Hurlburt P., Janeway C.J. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997, 388:394-397.
5. Akira S., Takeda K., Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001, 2:675-680.
6. Kaisho T., Akira S. Toll like receptor. Innate immunity 2003, 177-189. Humana Press, Totowa, NJ. R.B.E. Alan, A.H. Jules (Eds.).
7. Akira S., Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
8. Roach J.C., Glusman G., Rowen L., Kaur A., Purcell M.K., Smith K.D., et al. The evolution of vertebrate Toll-like receptors. Proc Natl Acad Sci USA 2005, 102:9577-9582.
9. Matsushima N., Tanaka T., Enkhbaya P., Mikami T., Taga M., Yamada K., et al. Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate Toll-like receptors. BMC Genomics 2007, 8:124.
10. Shimazu R., Akashi S., Ogata H., Nagai F., Fukudome K., Miyake K., et al. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J Exp Med 1999, 189:1777-1782.
11. Schromn A.B., Lien E., Henneke P., Chow J.C., Yoshimura A., Heine H., et al. Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling. J Exp Med 2001, 194:79-88.
12. Nagai Y., Akashi S., Nagafuku M., Ogata M., Iwakura Y., Akira S., et al. Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat Immunol 2002, 3:667-672.
13. Kim H., Park B., Kim J., Kim S., Lee J., Oh S., et al. Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran. Cell 2007, 130:906-917.
14. Ohto U., Fukase K., Miyake K., Satow Y. Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa. Science 2007, 316:1632-1634.
15. Park B.S., Song D.H., Kim H.M., Choi B.-S., Lee H., Lee J.-O. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature 2009, 458:1191-1195.
16. Saitoh S., Akashi S., Yamada T., Tanimura N., Kobayashi M., Konno K., et al. Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization. Int Immunol 2004, 16:961-969.
17. Akashi S., Nagai Y., Ogata H., Oikawa M., Fukase K., Kusumoto S., et al. Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition. Int Immunol 2001, 13:1595-1599.
18. Muroi M., Tanamoto K. Structural regions of MD-2 that determine the agonist-antagonist activity of lipid IVa. J Biol Chem 2006, 281:5484-5491.
19. Walsh C., Gangloff M., Monie T., Smith T., Wei B., McKinley T.J., et al. Elucidation of the MD-2/TLR4 interface required for signaling by lipid IVa. J Immunol 2008, 181:1245-1254.
20. Arnold K., Bordoli L., Kopp J., Schwede T. The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling. Bioinformatics 2006, 22:195-201.
21. Kraulis P.J. MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures. J Appl Crystallogr 1991, 24:946-950.
22. Fenn T.D., Ringe D., Petsko G.A. POVScript+: a program for model and data visualization using persistence of vision ray-tracing. J Appl Crystallogr 2003, 36:944-947.
23. Thompson J.D., Higgins D.G., Gibson T.J. ClustalW: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucl Acids Res 1994, 22:4673-4680.
24. Guindon S., Gascuel O. A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. Syst Biol 2003, 52:696-704.
25. Jones D., Taylor W., Thornton J. The rapid generation of mutation data matrices from protein sequences. Comput Appl Biosci 1992, 8:275-282.
26. Viriyakosol S., McCray P.B., Ashbaugh M.E., Chu J., Jia H.P., Weiss J., et al. Characterization of monoclonal antibodies to human soluble MD-2 protein. Hybridoma 2006, 25:349-357.
27. Hamann L., Kumpf O., Muller M., Visintin A., Eckert J., Schlag P.M., et al. A coding mutation within the first exon of the human MD-2 gene results in decreased lipopolysaccharide-induced signaling. Genes Immunity 2004, 5:283-288.
28. Re F., Strominger J.L. Separate functional domains of human MD-2 mediate Toll-like receptor 4-binding and lipopolysaccharide responsiveness. J Immunol 2003, 171:5272-5276.
29. Ohishi K., Zenitani R., Bando T., Goto Y., Uchida K., Maruyama T., et al. Pathological and serological evidence of Brucella-infection in baleen whales (Mysticeti) in the western North Pacific. Comp Immunol Microbiol Infect Dis 2003, 26:125-136.