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Volumn 4, Issue 4, 2010, Pages 302-315

Striatal pathology underlies prion infection-mediated hyperactivity in mice

Author keywords

Home cage; Neurodegeneration; Protein misfolding; PrP; Transmissible spongiform encephalopathy

Indexed keywords

ACETYLCHOLINE; BIOLOGICAL MARKER; DOPAMINE; GLIAL FIBRILLARY ACIDIC PROTEIN; NORADRENALIN; PRION PROTEIN; PROTEIN; PROTEIN IBA1; SEROTONIN; UNCLASSIFIED DRUG;

EID: 78650185885     PISSN: 19336896     EISSN: 1933690X     Source Type: Journal    
DOI: 10.4161/pri.4.4.13721     Document Type: Article
Times cited : (7)

References (60)
  • 1
    • 77649202326 scopus 로고    scopus 로고
    • Protein aggregation diseases: Pathogenicity and therapeutic perspectives
    • Aguzzi A, O'Connor T. Protein aggregation diseases: pathogenicity and therapeutic perspectives. Nat Rev Drug Discov 2010; 9:237-48.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 237-248
    • Aguzzi, A.1    O'Connor, T.2
  • 2
    • 70349705441 scopus 로고    scopus 로고
    • Prions: Protein aggregation and infectious diseases
    • Aguzzi A, Calella AM. Prions: protein aggregation and infectious diseases. Physiol Rev 2009; 89:1105-52.
    • (2009) Physiol Rev , vol.89 , pp. 1105-1152
    • Aguzzi, A.1    Calella, A.M.2
  • 4
    • 0020321767 scopus 로고
    • Novel proteinaceous infectious particles cause scrapie
    • Prusiner SB. Novel proteinaceous infectious particles cause scrapie. Science 1982; 216:136-44.
    • (1982) Science , vol.216 , pp. 136-144
    • Prusiner, S.B.1
  • 5
    • 77649213673 scopus 로고    scopus 로고
    • Generating a prion with bacterially expressed recombinant prion protein
    • Wang F, Wang X, Yuan CG, Ma J. Generating a prion with bacterially expressed recombinant prion protein. Science 2010; 327:1132-5.
    • (2010) Science , vol.327 , pp. 1132-1135
    • Wang, F.1    Wang, X.2    Yuan, C.G.3    Ma, J.4
  • 6
    • 68949163542 scopus 로고    scopus 로고
    • Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
    • Jackson WS, Borkowski AW, Faas H, Steele AD, King OD, Watson N, et al. Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice. Neuron 2009; 63:438-50.
    • (2009) Neuron , vol.63 , pp. 438-450
    • Jackson, W.S.1    Borkowski, A.W.2    Faas, H.3    Steele, A.D.4    King, O.D.5    Watson, N.6
  • 9
    • 34249993165 scopus 로고    scopus 로고
    • The prion strain phenomenon: Molecular basis and unprecedented features
    • DOI 10.1016/j.bbadis.2006.12.006, PII S0925443906002729, Prion-Related Disorders
    • Morales R, Abid K, Soto C. The prion strain phenomenon: molecular basis and unprecedented features. Biochim Biophys Acta 2007; 1772:681-91. (Pubitemid 46887653)
    • (2007) Biochimica et Biophysica Acta - Molecular Basis of Disease , vol.1772 , Issue.6 , pp. 681-691
    • Morales, R.1    Abid, K.2    Soto, C.3
  • 11
    • 36348958583 scopus 로고    scopus 로고
    • Diminishing apoptosis by deletion of bax or overexpression of Bcl-2 does not protect against infectious prion toxicity in vivo
    • DOI 10.1523/JNEUROSCI.3290-07.2007
    • Steele AD, King OD, Jackson WS, Hetz CA, Borkowski AW, Thielen P, et al. Diminishing apoptosis by deletion of Bax or overexpression of Bcl-2 does not protect against infectious prion toxicity in vivo. J Neurosci 2007; 27:13022-7. (Pubitemid 350159568)
    • (2007) Journal of Neuroscience , vol.27 , Issue.47 , pp. 13022-13027
    • Steele, A.D.1    King, O.D.2    Jackson, W.S.3    Hetz, C.A.4    Borkowski, A.W.5    Thielen, P.6    Wollmann, R.7    Lindquist, S.8
  • 13
    • 56349151227 scopus 로고    scopus 로고
    • The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration
    • Chen D, Steele AD, Hutter G, Bruno J, Govindarajan A, Easlon E, et al. The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration. Exp Gerontol 2008; 43:1086-93.
    • (2008) Exp Gerontol , vol.43 , pp. 1086-1093
    • Chen, D.1    Steele, A.D.2    Hutter, G.3    Bruno, J.4    Govindarajan, A.5    Easlon, E.6
  • 15
    • 48249108696 scopus 로고    scopus 로고
    • Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease
    • White MD, Farmer M, Mirabile I, Brandner S, Collinge J, Mallucci GR. Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease. Proc Natl Acad Sci USA 2008; 105:10238-43.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10238-10243
    • White, M.D.1    Farmer, M.2    Mirabile, I.3    Brandner, S.4    Collinge, J.5    Mallucci, G.R.6
  • 17
    • 0037450356 scopus 로고    scopus 로고
    • PDAPP; YFP double transgenic mice: A tool to study amyloid-beta associated changes in axonal, dendritic and synaptic structures
    • Brendza RP, O'Brien C, Simmons K, McKeel DW, Bales KR, Paul SM, et al. PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic and synaptic structures. J Comp Neurol 2003; 456:375-83.
    • (2003) J Comp Neurol , vol.456 , pp. 375-383
    • Brendza, R.P.1    O'Brien, C.2    Simmons, K.3    McKeel, D.W.4    Bales, K.R.5    Paul, S.M.6
  • 18
    • 0033951734 scopus 로고    scopus 로고
    • Application of silver degeneration stains for neurotoxicity testing
    • Switzer RC, 3rd. Application of silver degeneration stains for neurotoxicity testing. Toxicol Pathol 2000; 28:70-83.
    • (2000) Toxicol Pathol , vol.28 , pp. 70-83
    • Switzer III, R.C.1
  • 19
    • 56349143278 scopus 로고    scopus 로고
    • Striatal plasticity and basal ganglia circuit function
    • Kreitzer AC, Malenka RC. Striatal plasticity and basal ganglia circuit function. Neuron 2008; 60:543-54.
    • (2008) Neuron , vol.60 , pp. 543-554
    • Kreitzer, A.C.1    Malenka, R.C.2
  • 20
    • 48249091260 scopus 로고    scopus 로고
    • Habits, rituals and the evaluative brain
    • Graybiel AM. Habits, rituals and the evaluative brain. Annu Rev Neurosci 2008; 31:359-87.
    • (2008) Annu Rev Neurosci , vol.31 , pp. 359-387
    • Graybiel, A.M.1
  • 21
    • 43849107133 scopus 로고    scopus 로고
    • Phencyclidine-induced locomotor hyperactivity is enhanced in mice after stereotaxic brain serotonin depletion
    • Martin S, van den Buuse M. Phencyclidine-induced locomotor hyperactivity is enhanced in mice after stereotaxic brain serotonin depletion. Behav Brain Res 2008; 191:289-93.
    • (2008) Behav Brain Res , vol.191 , pp. 289-293
    • Martin, S.1    Van Den Buuse, M.2
  • 22
    • 16844362402 scopus 로고    scopus 로고
    • Corelease of dopamine and serotonin from striatal dopamine terminals
    • Zhou FM, Liang Y, Salas R, Zhang L, De Biasi M, Dani JA. Corelease of dopamine and serotonin from striatal dopamine terminals. Neuron 2005; 46:65-74.
    • (2005) Neuron , vol.46 , pp. 65-74
    • Zhou, F.M.1    Liang, Y.2    Salas, R.3    Zhang, L.4    De Biasi, M.5    Dani, J.A.6
  • 23
    • 64849093666 scopus 로고    scopus 로고
    • Early dysfunction of central 5-HT system in a murine model of bovine spongiform encephalopathy
    • Vidal C, Herzog C, Haeberle AM, Bombarde C, Miquel MC, Carimalo J, et al. Early dysfunction of central 5-HT system in a murine model of bovine spongiform encephalopathy. Neuroscience 2009; 160:731-43.
    • (2009) Neuroscience , vol.160 , pp. 731-743
    • Vidal, C.1    Herzog, C.2    Haeberle, A.M.3    Bombarde, C.4    Miquel, M.C.5    Carimalo, J.6
  • 24
    • 0030929562 scopus 로고    scopus 로고
    • Distribution of parvalbumin-immunoreactive neurons in brain correlates with hippocampal and temporal cortical pathology in Creutzfeldt-Jakob disease
    • Guentchev M, Hainfellner JA, Trabattoni GR, Budka H. Distribution of parvalbumin-immunoreactive neurons in brain correlates with hippocampal and temporal cortical pathology in Creutzfeldt-Jakob disease. J Neuropathol Exp Neurol 1997; 56:1119-24. (Pubitemid 27430473)
    • (1997) Journal of Neuropathology and Experimental Neurology , vol.56 , Issue.10 , pp. 1119-1124
    • Guentchev, M.1    Hainfellner, J.-A.2    Trabattoni, G.R.3    Budka, H.4
  • 25
    • 0032885694 scopus 로고    scopus 로고
    • Early destruction of the extracellular matrix around parvalbumin- immunoreactive interneurons in Creutzfeldt-Jakob disease
    • Belichenko PV, Miklossy J, Belser B, Budka H, Celio MR. Early destruction of the extracellular matrix around parvalbumin-immunoreactive interneurons in Creutzfeldt-Jakob disease. Neurobiol Dis 1999; 6:269-79.
    • (1999) Neurobiol Dis , vol.6 , pp. 269-279
    • Belichenko, P.V.1    Miklossy, J.2    Belser, B.3    Budka, H.4    Celio, M.R.5
  • 26
    • 57149104635 scopus 로고    scopus 로고
    • Interplay of beta2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion
    • Avale ME, Faure P, Pons S, Robledo P, Deltheil T, David DJ, et al. Interplay of beta2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion. Proc Natl Acad Sci USA 2008; 105:15991-6.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 15991-15996
    • Avale, M.E.1    Faure, P.2    Pons, S.3    Robledo, P.4    Deltheil, T.5    David, D.J.6
  • 27
    • 77954836905 scopus 로고    scopus 로고
    • Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors
    • Drenan RM, Grady SR, Steele AD, McKinney S, Patzlaff NE, McIntosh JM, et al. Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors. J Neurosci 2010; 30:9877-89.
    • (2010) J Neurosci , vol.30 , pp. 9877-9889
    • Drenan, R.M.1    Grady, S.R.2    Steele, A.D.3    McKinney, S.4    Patzlaff, N.E.5    McIntosh, J.M.6
  • 28
    • 53049110169 scopus 로고    scopus 로고
    • In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha6 nicotinic acetylcholine receptors
    • Drenan RM, Grady SR, Whiteaker P, McClure-Begley T, McKinney S, Miwa JM, et al. In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha6 nicotinic acetylcholine receptors. Neuron 2008; 60:123-36.
    • (2008) Neuron , vol.60 , pp. 123-136
    • Drenan, R.M.1    Grady, S.R.2    Whiteaker, P.3    McClure-Begley, T.4    McKinney, S.5    Miwa, J.M.6
  • 29
    • 60549092240 scopus 로고    scopus 로고
    • The locus coeruleus and noradrenergic modulation of cognition
    • Sara SJ. The locus coeruleus and noradrenergic modulation of cognition. Nat Rev Neurosci 2009; 10:211-23.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 211-223
    • Sara, S.J.1
  • 32
    • 18744402716 scopus 로고    scopus 로고
    • Early behavioural changes in mice infected with BSE and scrapie: Automated home cage monitoring reveals prion strain differences
    • Dell'Omo G, Vannoni E, Vyssotski AL, Di Bari MA, Nonno R, Agrimi U, et al. Early behavioural changes in mice infected with BSE and scrapie: automated home cage monitoring reveals prion strain differences. Eur J Neurosci 2002; 16:735-42.
    • (2002) Eur J Neurosci , vol.16 , pp. 735-742
    • Dell'Omo, G.1    Vannoni, E.2    Vyssotski, A.L.3    Di Bari, M.A.4    Nonno, R.5    Agrimi, U.6
  • 34
    • 58149401232 scopus 로고    scopus 로고
    • Prion strain targeting independent of strain-specific neuronal tropism
    • Ayers JI, Kincaid AE, Bartz JC. Prion strain targeting independent of strain-specific neuronal tropism. J Virol 2009; 83:81-7.
    • (2009) J Virol , vol.83 , pp. 81-87
    • Ayers, J.I.1    Kincaid, A.E.2    Bartz, J.C.3
  • 35
    • 0026583834 scopus 로고
    • Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent
    • Bessen RA, Marsh RF. Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent. J Virol 1992; 66:2096-101.
    • (1992) J Virol , vol.66 , pp. 2096-2101
    • Bessen, R.A.1    Marsh, R.F.2
  • 36
    • 0026558780 scopus 로고
    • Identification of two biologically distinct strains of transmissible mink encephalopathy in hamsters
    • Bessen RA, Marsh RF. Identification of two biologically distinct strains of transmissible mink encephalopathy in hamsters. J Gen Virol 1992; 73:329-34.
    • (1992) J Gen Virol , vol.73 , pp. 329-334
    • Bessen, R.A.1    Marsh, R.F.2
  • 37
    • 15944385293 scopus 로고    scopus 로고
    • Neuropathologically distinct prion strains give rise to similar temporal profiles of behavioral deficits
    • DOI 10.1016/j.nbd.2004.08.015
    • Cunningham C, Deacon RM, Chan K, Boche D, Rawlins JN, Perry VH. Neuropathologically distinct prion strains give rise to similar temporal profiles of behavioral deficits. Neurobiol Dis 2005; 18:258-69. (Pubitemid 40431109)
    • (2005) Neurobiology of Disease , vol.18 , Issue.2 , pp. 258-269
    • Cunningham, C.1    Deacon, R.M.J.2    Chan, K.3    Boche, D.4    Rawlins, J.N.P.5    Perry, V.H.6
  • 38
    • 0141954054 scopus 로고    scopus 로고
    • Conditional ablation of striatal neuronal types containing dopamine D2 receptor disturbs coordination of basal ganglia function
    • Sano H, Yasoshima Y, Matsushita N, Kaneko T, Kohno K, Pastan I, et al. Conditional ablation of striatal neuronal types containing dopamine D2 receptor disturbs coordination of basal ganglia function. J Neurosci 2003; 23:9078-88.
    • (2003) J Neurosci , vol.23 , pp. 9078-9088
    • Sano, H.1    Yasoshima, Y.2    Matsushita, N.3    Kaneko, T.4    Kohno, K.5    Pastan, I.6
  • 39
    • 34247217935 scopus 로고    scopus 로고
    • Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity and impaired oral behavior
    • Gantois I, Fang K, Jiang L, Babovic D, Lawrence AJ, Ferreri V, et al. Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity and impaired oral behavior. Proc Natl Acad Sci USA 2007; 104:4182-7.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 4182-4187
    • Gantois, I.1    Fang, K.2    Jiang, L.3    Babovic, D.4    Lawrence, A.J.5    Ferreri, V.6
  • 40
    • 30744441393 scopus 로고    scopus 로고
    • Locomotor hyperactivity and alterations in dopamine neurotransmission are associated with overexpression of A53T mutant human alpha-synuclein in mice
    • Unger EL, Eve DJ, Perez XA, Reichenbach DK, Xu Y, Lee MK, et al. Locomotor hyperactivity and alterations in dopamine neurotransmission are associated with overexpression of A53T mutant human alpha-synuclein in mice. Neurobiol Dis 2006; 21:431-43.
    • (2006) Neurobiol Dis , vol.21 , pp. 431-443
    • Unger, E.L.1    Eve, D.J.2    Perez, X.A.3    Reichenbach, D.K.4    Xu, Y.5    Lee, M.K.6
  • 42
    • 38349190626 scopus 로고    scopus 로고
    • Alterations in serotonin signalling are involved in the hyperactivity of Pitx3-deficient mice
    • Smits SM, Noorlander CW, Kas MJ, Ramakers GM, Smidt MP. Alterations in serotonin signalling are involved in the hyperactivity of Pitx3-deficient mice. Eur J Neurosci 2008; 27:388-95.
    • (2008) Eur J Neurosci , vol.27 , pp. 388-395
    • Smits, S.M.1    Noorlander, C.W.2    Kas, M.J.3    Ramakers, G.M.4    Smidt, M.P.5
  • 43
    • 13044283415 scopus 로고    scopus 로고
    • Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice
    • Gomeza J, Zhang L, Kostenis E, Felder C, Bymaster F, Brodkin J, et al. Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice. Proc Natl Acad Sci USA 1999; 96:10483-8.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 10483-10488
    • Gomeza, J.1    Zhang, L.2    Kostenis, E.3    Felder, C.4    Bymaster, F.5    Brodkin, J.6
  • 44
    • 67349280983 scopus 로고    scopus 로고
    • Selective presynaptic degeneration in the synaptopathy associated with ME7-induced hippocampal pathology
    • Gray BC, Siskova Z, Perry VH, O'Connor V. Selective presynaptic degeneration in the synaptopathy associated with ME7-induced hippocampal pathology. Neurobiol Dis 2009; 35:63-74.
    • (2009) Neurobiol Dis , vol.35 , pp. 63-74
    • Gray, B.C.1    Siskova, Z.2    Perry, V.H.3    O'Connor, V.4
  • 45
    • 77956556520 scopus 로고    scopus 로고
    • Morphological and functional abnormalities in mitochondria associated with synaptic degeneration in prion disease
    • Siskova Z, Mahad DJ, Pudney C, Campbell G, Cadogan M, Asuni A, et al. Morphological and functional abnormalities in mitochondria associated with synaptic degeneration in prion disease. Am J Pathol 2010; 177:1411-21.
    • (2010) Am J Pathol , vol.177 , pp. 1411-1421
    • Siskova, Z.1    Mahad, D.J.2    Pudney, C.3    Campbell, G.4    Cadogan, M.5    Asuni, A.6
  • 46
    • 73549119497 scopus 로고    scopus 로고
    • Degenerating synaptic boutons in prion disease: Microglia activation without synaptic stripping
    • Siskova Z, Page A, O'Connor V, Perry VH. Degenerating synaptic boutons in prion disease: microglia activation without synaptic stripping. Am J Pathol 2009; 175:1610-21.
    • (2009) Am J Pathol , vol.175 , pp. 1610-1621
    • Siskova, Z.1    Page, A.2    O'Connor, V.3    Perry, V.H.4
  • 47
    • 77953249289 scopus 로고    scopus 로고
    • Reactive hypertrophy of synaptic varicosities within the hippocampus of prion-infected mice
    • Siskova Z, Sanyal NK, Orban A, O'Connor V, Perry VH. Reactive hypertrophy of synaptic varicosities within the hippocampus of prion-infected mice. Biochem Soc Trans 2010; 38:471-5.
    • (2010) Biochem Soc Trans , vol.38 , pp. 471-475
    • Siskova, Z.1    Sanyal, N.K.2    Orban, A.3    O'Connor, V.4    Perry, V.H.5
  • 48
    • 61349201380 scopus 로고    scopus 로고
    • Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers
    • Lauren J, Gimbel DA, Nygaard HB, Gilbert JW, Strittmatter SM. Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers. Nature 2009; 457:1128-32.
    • (2009) Nature , vol.457 , pp. 1128-1132
    • Lauren, J.1    Gimbel, D.A.2    Nygaard, H.B.3    Gilbert, J.W.4    Strittmatter, S.M.5
  • 50
    • 77956197815 scopus 로고    scopus 로고
    • Interaction between human prion protein and amyloid-beta (Abeta) oligomers: Role of N-terminal residues
    • Chen S, Yadav SP, Surewicz WK. Interaction between human prion protein and amyloid-beta (Abeta) oligomers: role OF N-terminal residues. J Biol Chem 2010; 285:26377-83.
    • (2010) J Biol Chem , vol.285 , pp. 26377-26383
    • Chen, S.1    Yadav, S.P.2    Surewicz, W.K.3
  • 51
    • 74249114011 scopus 로고    scopus 로고
    • Prion protein and Alzheimer disease
    • Kellett KA, Hooper NM. Prion protein and Alzheimer disease. Prion 2009; 3:190-4.
    • (2009) Prion , vol.3 , pp. 190-194
    • Kellett, K.A.1    Hooper, N.M.2
  • 52
    • 76649093635 scopus 로고    scopus 로고
    • Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein
    • Balducci C, Beeg M, Stravalaci M, Bastone A, Sclip A, Biasini E, et al. Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein. Proc Natl Acad Sci USA 2010; 107:2295-300.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2295-2300
    • Balducci, C.1    Beeg, M.2    Stravalaci, M.3    Bastone, A.4    Sclip, A.5    Biasini, E.6
  • 55
    • 34249795501 scopus 로고    scopus 로고
    • Polymorphisms at codons 129 and 219 of the prion protein gene (PRNP) are not associated with sporadic Alzheimer's disease in the Korean population
    • Jeong BH, Lee KH, Jeong YE, Hwang KA, Lee YJ, Carp RI, et al. Polymorphisms at codons 129 and 219 of the prion protein gene (PRNP) are not associated with sporadic Alzheimer's disease in the Korean population. Eur J Neurol 2007; 14:621-6.
    • (2007) Eur J Neurol , vol.14 , pp. 621-626
    • Jeong, B.H.1    Lee, K.H.2    Jeong, Y.E.3    Hwang, K.A.4    Lee, Y.J.5    Carp, R.I.6
  • 56
    • 77951183978 scopus 로고    scopus 로고
    • Prion-like disorders: Blurring the divide between transmissibility and infectivity
    • Cushman M, Johnson BS, King OD, Gitler AD, Shorter J. Prion-like disorders: blurring the divide between transmissibility and infectivity. J Cell Sci 2010; 123:1191-201.
    • (2010) J Cell Sci , vol.123 , pp. 1191-1201
    • Cushman, M.1    Johnson, B.S.2    King, O.D.3    Gitler, A.D.4    Shorter, J.5
  • 57
    • 33846917641 scopus 로고    scopus 로고
    • The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases
    • Steele AD, Jackson WS, King OD, Lindquist S. The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases. Proc Natl Acad Sci USA 2007; 104:1983-8.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 1983-1988
    • Steele, A.D.1    Jackson, W.S.2    King, O.D.3    Lindquist, S.4
  • 58
    • 0028132219 scopus 로고
    • Use of an amino-cupric-silver technique for the detection of early and semiacute neuronal degeneration caused by neurotoxicants, hypoxia and physical trauma
    • de Olmos JS, Beltramino CA, de Olmos de Lorenzo S. Use of an amino-cupric-silver technique for the detection of early and semiacute neuronal degeneration caused by neurotoxicants, hypoxia and physical trauma. Neurotoxicol Teratol 1994; 16:545-61.
    • (1994) Neurotoxicol Teratol , vol.16 , pp. 545-561
    • De Olmos, J.S.1    Beltramino, C.A.2    De Olmos De Lorenzo, S.3
  • 59
    • 0033045425 scopus 로고    scopus 로고
    • The efficiency of systematic sampling in stereology - Reconsidered
    • Gundersen HJ, Jensen EB, Kieu K, Nielsen J. The efficiency of systematic sampling in stereology - reconsidered. J Microsc 1999; 193:199-211.
    • (1999) J Microsc , vol.193 , pp. 199-211
    • Gundersen, H.J.1    Jensen, E.B.2    Kieu, K.3    Nielsen, J.4
  • 60
    • 36148957510 scopus 로고    scopus 로고
    • Neuropathological quantification of dtg APP/PS1: Neuroimaging, stereology and biochemistry
    • Dordr
    • Manaye KF, Wang PC, O'Neil JN, Huang SY, Xu T, Lei DL, et al. Neuropathological quantification of dtg APP/PS1: neuroimaging, stereology and biochemistry. Age (Dordr) 2007; 29:87-96.
    • (2007) Age , vol.29 , pp. 87-96
    • Manaye, K.F.1    Wang, P.C.2    O'Neil, J.N.3    Huang, S.Y.4    Xu, T.5    Lei, D.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.