메뉴 건너뛰기




Volumn 160, Issue 4, 2009, Pages 731-743

Early dysfunction of central 5-HT system in a murine model of bovine spongiform encephalopathy

Author keywords

5 HT; BSE; neurodegenerative disease; prion; raphe; suprachiasmatic nucleus

Indexed keywords

PRION PROTEIN;

EID: 64849093666     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.02.072     Document Type: Article
Times cited : (16)

References (76)
  • 1
    • 3042640899 scopus 로고    scopus 로고
    • Anxiolytic-like effects of median raphe nucleus lesion in the elevated T-maze
    • Andrade T.G., Macedo C.E., Zangrossi Jr. H., and Graeff F.G. Anxiolytic-like effects of median raphe nucleus lesion in the elevated T-maze. Behav Brain Res 153 (2004) 55-60
    • (2004) Behav Brain Res , vol.153 , pp. 55-60
    • Andrade, T.G.1    Macedo, C.E.2    Zangrossi Jr., H.3    Graeff, F.G.4
  • 3
    • 0023112534 scopus 로고
    • Impairment of the cortical and thalamic electrical activity in scrapie-infected rats
    • Bassant M.H., Court L., and Cathala F. Impairment of the cortical and thalamic electrical activity in scrapie-infected rats. Electroencephalogr Clin Neurophysiol 66 (1987) 307-316
    • (1987) Electroencephalogr Clin Neurophysiol , vol.66 , pp. 307-316
    • Bassant, M.H.1    Court, L.2    Cathala, F.3
  • 5
    • 0022529596 scopus 로고
    • Changes in the serotonergic, noradrenergic and dopaminergic levels in the brain of scrapie-infected rats
    • Bassant M.H., Picard M., Olichon D., Cathala F., and Court L. Changes in the serotonergic, noradrenergic and dopaminergic levels in the brain of scrapie-infected rats. Brain Res 367 (1986) 360-363
    • (1986) Brain Res , vol.367 , pp. 360-363
    • Bassant, M.H.1    Picard, M.2    Olichon, D.3    Cathala, F.4    Court, L.5
  • 6
    • 15844376730 scopus 로고    scopus 로고
    • Serotonin neurotoxins-past and present
    • Baumgarten H.G., and Lachenmayer L. Serotonin neurotoxins-past and present. Neurotox Res 6 (2004) 589-614
    • (2004) Neurotox Res , vol.6 , pp. 589-614
    • Baumgarten, H.G.1    Lachenmayer, L.2
  • 7
    • 0025815784 scopus 로고
    • Direct evidence for an important species difference in the mechanism of 8-OH-DPAT-induced hypothermia
    • Bill D.J., Knight M., Forster E.A., and Fletcher A. Direct evidence for an important species difference in the mechanism of 8-OH-DPAT-induced hypothermia. Br J Pharmacol 103 (1991) 1857-1864
    • (1991) Br J Pharmacol , vol.103 , pp. 1857-1864
    • Bill, D.J.1    Knight, M.2    Forster, E.A.3    Fletcher, A.4
  • 8
    • 0025267002 scopus 로고
    • Effect of serotonergic lesion on "anxious" behaviour measured in the elevated plus-maze test in the rat
    • Briley M., Chopin P., and Moret C. Effect of serotonergic lesion on "anxious" behaviour measured in the elevated plus-maze test in the rat. Psychopharmacology (Berl) 101 (1990) 187-189
    • (1990) Psychopharmacology (Berl) , vol.101 , pp. 187-189
    • Briley, M.1    Chopin, P.2    Moret, C.3
  • 11
    • 0034916581 scopus 로고    scopus 로고
    • Prion diseases of humans and animals: their causes and molecular basis
    • Collinge J. Prion diseases of humans and animals: their causes and molecular basis. Annu Rev Neurosci 24 (2001) 519-550
    • (2001) Annu Rev Neurosci , vol.24 , pp. 519-550
    • Collinge, J.1
  • 12
    • 37549022670 scopus 로고    scopus 로고
    • Serotoninergic regulation of emotional and behavioural control processes
    • Cools R., Roberts A.C., and Robbins T.W. Serotoninergic regulation of emotional and behavioural control processes. Trends Cogn Sci 12 (2008) 31-40
    • (2008) Trends Cogn Sci , vol.12 , pp. 31-40
    • Cools, R.1    Roberts, A.C.2    Robbins, T.W.3
  • 13
    • 0034848165 scopus 로고    scopus 로고
    • Alteration of the serotoninergic system in fatal familial insomnia
    • Cortelli P., Polinsky R., Montagna P., and Lugaresi E. Alteration of the serotoninergic system in fatal familial insomnia. Ann Neurol 50 (2001) 421-422
    • (2001) Ann Neurol , vol.50 , pp. 421-422
    • Cortelli, P.1    Polinsky, R.2    Montagna, P.3    Lugaresi, E.4
  • 15
    • 0019823545 scopus 로고
    • Neuropharmacologic specificity of a simple animal model for the behavioral actions of benzodiazepines
    • Crawley J.N. Neuropharmacologic specificity of a simple animal model for the behavioral actions of benzodiazepines. Pharmacol Biochem Behav 15 (1981) 695-699
    • (1981) Pharmacol Biochem Behav , vol.15 , pp. 695-699
    • Crawley, J.N.1
  • 16
    • 0021848567 scopus 로고
    • Neurotransmitter metabolites, enzymes and receptors in experimental scrapie
    • Cross A.J., Kimberlin R.H., Crow T.J., Johnson J.A., and Walker C.A. Neurotransmitter metabolites, enzymes and receptors in experimental scrapie. J Neurol Sci 70 (1985) 231-241
    • (1985) J Neurol Sci , vol.70 , pp. 231-241
    • Cross, A.J.1    Kimberlin, R.H.2    Crow, T.J.3    Johnson, J.A.4    Walker, C.A.5
  • 17
    • 18744402716 scopus 로고    scopus 로고
    • Early behavioural changes in mice infected with BSE and scrapie: automated home cage monitoring reveals prion strain differences
    • Dell'Omo G., Vannoni E., Vyssotski A.L., Di Bari M.A., Nonno R., Agrimi U., and Lipp H.P. Early behavioural changes in mice infected with BSE and scrapie: automated home cage monitoring reveals prion strain differences. Eur J Neurosci 16 (2002) 735-742
    • (2002) Eur J Neurosci , vol.16 , pp. 735-742
    • Dell'Omo, G.1    Vannoni, E.2    Vyssotski, A.L.3    Di Bari, M.A.4    Nonno, R.5    Agrimi, U.6    Lipp, H.P.7
  • 18
    • 0023717432 scopus 로고
    • Apparent hyperalgesia in the mouse tail-flick test due to increased tail skin temperature after lesioning of serotonergic pathways
    • Eide P.K., Berge O.G., Tjolsen A., and Hole K. Apparent hyperalgesia in the mouse tail-flick test due to increased tail skin temperature after lesioning of serotonergic pathways. Acta Physiol Scand 134 (1988) 413-420
    • (1988) Acta Physiol Scand , vol.134 , pp. 413-420
    • Eide, P.K.1    Berge, O.G.2    Tjolsen, A.3    Hole, K.4
  • 19
    • 0014308027 scopus 로고
    • The sequential development of the brain lesion of scrapie in three strains of mice
    • Fraser H., and Dickinson A.G. The sequential development of the brain lesion of scrapie in three strains of mice. J Comp Pathol 78 (1968) 301-311
    • (1968) J Comp Pathol , vol.78 , pp. 301-311
    • Fraser, H.1    Dickinson, A.G.2
  • 20
    • 0022375835 scopus 로고
    • Presynaptic serotonin receptor-mediated response in mice attenuated by antidepressant drugs and electroconvulsive shock
    • Goodwin G.M., De Souza R.J., and Green A.R. Presynaptic serotonin receptor-mediated response in mice attenuated by antidepressant drugs and electroconvulsive shock. Nature 317 (1985) 531-533
    • (1985) Nature , vol.317 , pp. 531-533
    • Goodwin, G.M.1    De Souza, R.J.2    Green, A.R.3
  • 21
    • 0022556620 scopus 로고
    • The effects of a 5-HT1 receptor ligand isapirone (TVX Q 7821) on 5-HT synthesis and the behavioural effects of 5-HT agonists in mice and rats
    • Goodwin G.M., De Souza R.J., and Green A.R. The effects of a 5-HT1 receptor ligand isapirone (TVX Q 7821) on 5-HT synthesis and the behavioural effects of 5-HT agonists in mice and rats. Psychopharmacology (Berl) 89 (1986) 382-387
    • (1986) Psychopharmacology (Berl) , vol.89 , pp. 382-387
    • Goodwin, G.M.1    De Souza, R.J.2    Green, A.R.3
  • 22
    • 0019413741 scopus 로고
    • Hypersensitivity to central serotonin receptor activation in scrapie-infected hamsters and the effect of serotonergic drugs on scrapie symptoms
    • Goudsmit J., Rohwer R.G., Silbergeld E.K., and Gajdusek D.C. Hypersensitivity to central serotonin receptor activation in scrapie-infected hamsters and the effect of serotonergic drugs on scrapie symptoms. Brain Res 220 (1981) 372-377
    • (1981) Brain Res , vol.220 , pp. 372-377
    • Goudsmit, J.1    Rohwer, R.G.2    Silbergeld, E.K.3    Gajdusek, D.C.4
  • 24
    • 0034883360 scopus 로고    scopus 로고
    • Early behavioural changes in scrapie-affected mice and the influence of dapsone
    • Guenther K., Deacon R.M., Perry V.H., and Rawlins J.N. Early behavioural changes in scrapie-affected mice and the influence of dapsone. Eur J Neurosci 14 (2001) 401-409
    • (2001) Eur J Neurosci , vol.14 , pp. 401-409
    • Guenther, K.1    Deacon, R.M.2    Perry, V.H.3    Rawlins, J.N.4
  • 25
    • 0028121033 scopus 로고
    • Neuropharmacology of anxiety: perspectives and prospects
    • Hamon M. Neuropharmacology of anxiety: perspectives and prospects. Trends Pharmacol Sci 15 (1994) 36-39
    • (1994) Trends Pharmacol Sci , vol.15 , pp. 36-39
    • Hamon, M.1
  • 26
    • 0030732238 scopus 로고    scopus 로고
    • Central 5-HT depletion enhances impulsive responding without affecting the accuracy of attentional performance: interactions with dopaminergic mechanisms
    • Harrison A.A., Everitt B.J., and Robbins T.W. Central 5-HT depletion enhances impulsive responding without affecting the accuracy of attentional performance: interactions with dopaminergic mechanisms. Psychopharmacology (Berl) 133 (1997) 329-342
    • (1997) Psychopharmacology (Berl) , vol.133 , pp. 329-342
    • Harrison, A.A.1    Everitt, B.J.2    Robbins, T.W.3
  • 27
    • 0032995030 scopus 로고    scopus 로고
    • Central serotonin depletion impairs both the acquisition and performance of a symmetrically reinforced go/no-go conditional visual discrimination
    • Harrison A.A., Everitt B.J., and Robbins T.W. Central serotonin depletion impairs both the acquisition and performance of a symmetrically reinforced go/no-go conditional visual discrimination. Behav Brain Res 100 (1999) 99-112
    • (1999) Behav Brain Res , vol.100 , pp. 99-112
    • Harrison, A.A.1    Everitt, B.J.2    Robbins, T.W.3
  • 29
    • 0036184935 scopus 로고    scopus 로고
    • Creutzfeldt-Jakob disease in elderly people
    • Henry C., Lowman A., and Will R.G. Creutzfeldt-Jakob disease in elderly people. Age Ageing 31 (2002) 7-10
    • (2002) Age Ageing , vol.31 , pp. 7-10
    • Henry, C.1    Lowman, A.2    Will, R.G.3
  • 30
    • 1142273439 scopus 로고    scopus 로고
    • Tissue distribution of bovine spongiform encephalopathy agent in primates after intravenous or oral infection
    • Herzog C., Sales N., Etchegaray N., Charbonnier A., Freire S., Dormont D., Deslys J.P., and Lasmezas C.I. Tissue distribution of bovine spongiform encephalopathy agent in primates after intravenous or oral infection. Lancet 363 (2004) 422-428
    • (2004) Lancet , vol.363 , pp. 422-428
    • Herzog, C.1    Sales, N.2    Etchegaray, N.3    Charbonnier, A.4    Freire, S.5    Dormont, D.6    Deslys, J.P.7    Lasmezas, C.I.8
  • 31
    • 0032841171 scopus 로고    scopus 로고
    • Sleep and serotonin: an unfinished story
    • Jouvet M. Sleep and serotonin: an unfinished story. Neuropsychopharmacology 21 (1999) 24S-27S
    • (1999) Neuropsychopharmacology , vol.21
    • Jouvet, M.1
  • 32
    • 0033012137 scopus 로고    scopus 로고
    • Scrapie-infected mice and PrP knockout mice share abnormal localization and activity of neuronal nitric oxide synthase
    • Keshet G.I., Ovadia H., Taraboulos A., and Gabizon R. Scrapie-infected mice and PrP knockout mice share abnormal localization and activity of neuronal nitric oxide synthase. J Neurochem 72 (1999) 1224-1231
    • (1999) J Neurochem , vol.72 , pp. 1224-1231
    • Keshet, G.I.1    Ovadia, H.2    Taraboulos, A.3    Gabizon, R.4
  • 33
    • 0023124898 scopus 로고
    • Incubation periods and survival times for mice injected stereotaxically with three scrapie strains in different brain regions
    • Kim Y.S., Carp R.I., Callahan S.M., and Wisniewski H.M. Incubation periods and survival times for mice injected stereotaxically with three scrapie strains in different brain regions. J Gen Virol 68 Pt 3 (1987) 695-702
    • (1987) J Gen Virol , vol.68 , Issue.PART 3 , pp. 695-702
    • Kim, Y.S.1    Carp, R.I.2    Callahan, S.M.3    Wisniewski, H.M.4
  • 35
    • 0036315938 scopus 로고    scopus 로고
    • Beta-CIT SPECT demonstrates reduced availability of serotonin transporters in patients with fatal familial insomnia
    • Kloppel S., Pirker W., Brucke T., Kovacs G.G., and Almer G. Beta-CIT SPECT demonstrates reduced availability of serotonin transporters in patients with fatal familial insomnia. J Neural Transm 109 (2002) 1105-1110
    • (2002) J Neural Transm , vol.109 , pp. 1105-1110
    • Kloppel, S.1    Pirker, W.2    Brucke, T.3    Kovacs, G.G.4    Almer, G.5
  • 36
    • 0028792194 scopus 로고
    • Lithium attenuates hypokinesia induced by immobilization stress in rats
    • Kofman O., Levin U., and Alpert C. Lithium attenuates hypokinesia induced by immobilization stress in rats. Prog Neuropsychopharmacol Biol Psychiatry 19 (1995) 1081-1090
    • (1995) Prog Neuropsychopharmacol Biol Psychiatry , vol.19 , pp. 1081-1090
    • Kofman, O.1    Levin, U.2    Alpert, C.3
  • 37
    • 0029922585 scopus 로고    scopus 로고
    • Strain specific and common pathogenic events in murine models of scrapie and bovine spongiform encephalopathy
    • Lasmezas C.I., Deslys J.P., Demaimay R., Adjou K.T., Hauw J.J., and Dormont D. Strain specific and common pathogenic events in murine models of scrapie and bovine spongiform encephalopathy. J Gen Virol 77 Pt 7 (1996) 1601-1609
    • (1996) J Gen Virol , vol.77 , Issue.PART 7 , pp. 1601-1609
    • Lasmezas, C.I.1    Deslys, J.P.2    Demaimay, R.3    Adjou, K.T.4    Hauw, J.J.5    Dormont, D.6
  • 39
    • 0026053705 scopus 로고
    • Mesocorticolimbic dopaminergic network: functional and regulatory roles
    • Le Moal M., and Simon H. Mesocorticolimbic dopaminergic network: functional and regulatory roles. Physiol Rev 71 (1991) 155-234
    • (1991) Physiol Rev , vol.71 , pp. 155-234
    • Le Moal, M.1    Simon, H.2
  • 40
    • 0021321567 scopus 로고
    • The determination of catecholamines, indoleamines, metabolites, and related enzyme activities using three micron liquid chromatography columns
    • Lin P.Y.T., Bulawa M.C., Wong P., Lin L., Scott J., and Blank C.L. The determination of catecholamines, indoleamines, metabolites, and related enzyme activities using three micron liquid chromatography columns. J Liq Chromatogr 7 (1984) 509-538
    • (1984) J Liq Chromatogr , vol.7 , pp. 509-538
    • Lin, P.Y.T.1    Bulawa, M.C.2    Wong, P.3    Lin, L.4    Scott, J.5    Blank, C.L.6
  • 43
    • 0026635623 scopus 로고
    • A BASIC computer program for analyzing endpoint assays
    • Lynn D.E. A BASIC computer program for analyzing endpoint assays. BioTechniques 12 (1992) 880-881
    • (1992) BioTechniques , vol.12 , pp. 880-881
    • Lynn, D.E.1
  • 44
    • 0242363656 scopus 로고    scopus 로고
    • Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis
    • Mallucci G., Dickinson A., Linehan J., Klohn P.C., Brandner S., and Collinge J. Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis. Science 302 (2003) 871-874
    • (2003) Science , vol.302 , pp. 871-874
    • Mallucci, G.1    Dickinson, A.2    Linehan, J.3    Klohn, P.C.4    Brandner, S.5    Collinge, J.6
  • 46
    • 0034597930 scopus 로고    scopus 로고
    • Anxiolytic action on the behavioural inhibition system implies multiple types of arousal contribute to anxiety
    • McNaughton N., and Gray J.A. Anxiolytic action on the behavioural inhibition system implies multiple types of arousal contribute to anxiety. J Affect Disord 61 (2000) 161-176
    • (2000) J Affect Disord , vol.61 , pp. 161-176
    • McNaughton, N.1    Gray, J.A.2
  • 48
    • 0036277865 scopus 로고    scopus 로고
    • Descending control of pain
    • Millan M.J. Descending control of pain. Prog Neurobiol 66 (2002) 355-474
    • (2002) Prog Neurobiol , vol.66 , pp. 355-474
    • Millan, M.J.1
  • 49
    • 0142216081 scopus 로고    scopus 로고
    • The neurobiology and control of anxious states
    • Millan M.J. The neurobiology and control of anxious states. Prog Neurobiol 70 (2003) 83-244
    • (2003) Prog Neurobiol , vol.70 , pp. 83-244
    • Millan, M.J.1
  • 50
    • 0025934838 scopus 로고
    • Depletion of brain serotonin by 5,7-DHT modifies hamster circadian rhythm response to light
    • Morin L.P., and Blanchard J. Depletion of brain serotonin by 5,7-DHT modifies hamster circadian rhythm response to light. Brain Res 566 (1991) 173-185
    • (1991) Brain Res , vol.566 , pp. 173-185
    • Morin, L.P.1    Blanchard, J.2
  • 53
    • 0034634427 scopus 로고    scopus 로고
    • Depletion of brain norepinephrine does not reduce spontaneous ambulatory activity of rats in the home cage
    • Murrough J.W., Boss-Williams K.A., Emery M.S., Bonsall R.W., and Weiss J.M. Depletion of brain norepinephrine does not reduce spontaneous ambulatory activity of rats in the home cage. Brain Res 883 (2000) 125-130
    • (2000) Brain Res , vol.883 , pp. 125-130
    • Murrough, J.W.1    Boss-Williams, K.A.2    Emery, M.S.3    Bonsall, R.W.4    Weiss, J.M.5
  • 55
    • 0034995278 scopus 로고    scopus 로고
    • Behavioral and neurochemical consequences of repeated nicotine treatment in the serotonin-depleted rat
    • Olausson P., Akesson P., Petersson A., Engel J.A., and Soderpalm B. Behavioral and neurochemical consequences of repeated nicotine treatment in the serotonin-depleted rat. Psychopharmacology (Berl) 155 (2001) 348-361
    • (2001) Psychopharmacology (Berl) , vol.155 , pp. 348-361
    • Olausson, P.1    Akesson, P.2    Petersson, A.3    Engel, J.A.4    Soderpalm, B.5
  • 56
    • 0030008814 scopus 로고    scopus 로고
    • Effect of scrapie infection on the activity of neuronal nitric-oxide synthase in brain and neuroblastoma cells
    • Ovadia H., Rosenmann H., Shezen E., Halimi M., Ofran I., and Gabizon R. Effect of scrapie infection on the activity of neuronal nitric-oxide synthase in brain and neuroblastoma cells. J Biol Chem 271 (1996) 16856-16861
    • (1996) J Biol Chem , vol.271 , pp. 16856-16861
    • Ovadia, H.1    Rosenmann, H.2    Shezen, E.3    Halimi, M.4    Ofran, I.5    Gabizon, R.6
  • 58
    • 0022466497 scopus 로고
    • Creutzfeldt-Jakob infection increases adenylate cyclase activity in specific regions of guinea pig brain
    • Rasenick M.M., Valley S., Manuelidis E.E., and Manuelidis L. Creutzfeldt-Jakob infection increases adenylate cyclase activity in specific regions of guinea pig brain. FEBS Lett 198 (1986) 164-168
    • (1986) FEBS Lett , vol.198 , pp. 164-168
    • Rasenick, M.M.1    Valley, S.2    Manuelidis, E.E.3    Manuelidis, L.4
  • 59
    • 1342280342 scopus 로고    scopus 로고
    • Dopamine and cognition
    • Robbins T.W. Dopamine and cognition. Curr Opin Neurol 16 Suppl 2 (2003) S1-S2
    • (2003) Curr Opin Neurol , vol.16 , Issue.SUPPL. 2
    • Robbins, T.W.1
  • 61
    • 0019407674 scopus 로고
    • Serotonin concentrations in brain and blood of scrapie-infected and normal hamsters and mice
    • Rohwer R.G., Neckers L.M., Trepel J.B., Gajdusek D.C., and Wyatt R.J. Serotonin concentrations in brain and blood of scrapie-infected and normal hamsters and mice. Brain Res 220 (1981) 367-371
    • (1981) Brain Res , vol.220 , pp. 367-371
    • Rohwer, R.G.1    Neckers, L.M.2    Trepel, J.B.3    Gajdusek, D.C.4    Wyatt, R.J.5
  • 62
    • 34447509815 scopus 로고    scopus 로고
    • Contributions of neuronal prion protein on sleep recovery and stress response following sleep deprivation
    • Sanchez-Alavez M., Conti B., Moroncini G., and Criado J.R. Contributions of neuronal prion protein on sleep recovery and stress response following sleep deprivation. Brain Res 1158 (2007) 71-80
    • (2007) Brain Res , vol.1158 , pp. 71-80
    • Sanchez-Alavez, M.1    Conti, B.2    Moroncini, G.3    Criado, J.R.4
  • 63
    • 0345687168 scopus 로고    scopus 로고
    • NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells
    • Schneider B., Mutel V., Pietri M., Ermonval M., Mouillet-Richard S., and Kellermann O. NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells. Proc Natl Acad Sci U S A 100 (2003) 13326-13331
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 13326-13331
    • Schneider, B.1    Mutel, V.2    Pietri, M.3    Ermonval, M.4    Mouillet-Richard, S.5    Kellermann, O.6
  • 64
    • 0025345275 scopus 로고
    • Destruction of the hamster serotonergic system by 5,7-DHT: effects on circadian rhythm phase, entrainment and response to triazolam
    • Smale L., Michels K.M., Moore R.Y., and Morin L.P. Destruction of the hamster serotonergic system by 5,7-DHT: effects on circadian rhythm phase, entrainment and response to triazolam. Brain Res 515 (1990) 9-19
    • (1990) Brain Res , vol.515 , pp. 9-19
    • Smale, L.1    Michels, K.M.2    Moore, R.Y.3    Morin, L.P.4
  • 65
    • 0037157534 scopus 로고    scopus 로고
    • First hundred cases of variant Creutzfeldt-Jakob disease: retrospective case note review of early psychiatric and neurological features
    • Spencer M.D., Knight R.S., and Will R.G. First hundred cases of variant Creutzfeldt-Jakob disease: retrospective case note review of early psychiatric and neurological features. BMJ 324 (2002) 1479-1482
    • (2002) BMJ , vol.324 , pp. 1479-1482
    • Spencer, M.D.1    Knight, R.S.2    Will, R.G.3
  • 66
    • 33846917641 scopus 로고    scopus 로고
    • The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases
    • Steele A.D., Jackson W.S., King O.D., and Lindquist S. The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases. Proc Natl Acad Sci U S A 104 (2007) 1983-1988
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 1983-1988
    • Steele, A.D.1    Jackson, W.S.2    King, O.D.3    Lindquist, S.4
  • 67
    • 0031047646 scopus 로고    scopus 로고
    • Sleep and sleep regulation in normal and prion protein-deficient mice
    • Tobler I., Deboer T., and Fischer M. Sleep and sleep regulation in normal and prion protein-deficient mice. J Neurol Sci 17 (1997) 1869-1879
    • (1997) J Neurol Sci , vol.17 , pp. 1869-1879
    • Tobler, I.1    Deboer, T.2    Fischer, M.3
  • 70
    • 29344472814 scopus 로고    scopus 로고
    • Preclinical metabolic changes in mouse prion diseases detected by 1H-nuclear magnetic resonance spectroscopy
    • Vidal C., Meric P., Provost F., Herzog C., Lasmezas C., Gillet B., Beloeil J.C., and Dormont D. Preclinical metabolic changes in mouse prion diseases detected by 1H-nuclear magnetic resonance spectroscopy. Neuroreport 17 (2006) 89-93
    • (2006) Neuroreport , vol.17 , pp. 89-93
    • Vidal, C.1    Meric, P.2    Provost, F.3    Herzog, C.4    Lasmezas, C.5    Gillet, B.6    Beloeil, J.C.7    Dormont, D.8
  • 74
    • 0032409890 scopus 로고    scopus 로고
    • Extensive degeneration of catecholaminergic neurons to scrapie agent 87V in the brains of IM mice
    • Yun S.W., Choi E.K., Ju W.K., Ahn M.S., Carp R.I., Wisniewski H.M., and Kim Y.S. Extensive degeneration of catecholaminergic neurons to scrapie agent 87V in the brains of IM mice. Mol Chem Neuropathol 34 (1998) 121-132
    • (1998) Mol Chem Neuropathol , vol.34 , pp. 121-132
    • Yun, S.W.1    Choi, E.K.2    Ju, W.K.3    Ahn, M.S.4    Carp, R.I.5    Wisniewski, H.M.6    Kim, Y.S.7
  • 75
    • 33747093723 scopus 로고    scopus 로고
    • Oxidative stress in the brain at early preclinical stages of mouse scrapie
    • Yun S.W., Gerlach M., Riederer P., and Klein M.A. Oxidative stress in the brain at early preclinical stages of mouse scrapie. Exp Neurol 201 (2006) 90-98
    • (2006) Exp Neurol , vol.201 , pp. 90-98
    • Yun, S.W.1    Gerlach, M.2    Riederer, P.3    Klein, M.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.