Polymorphisms at codons 129 and 219 of the prion protein gene (PRNP) are not associated with sporadic Alzheimer's disease in the Korean population

European Journal of Neurology

Volumn 14, Issue 6, 2007, Pages 621-626

  Jeong, B H ^a   Lee, K H ^b   Jeong, Y E ^b   Hwang, K A ^b   Lee, Y J ^a   Carp, R I ^c   Ju, Y R ^b   Kim, Y S ^a  

^a Hallym University   (South Korea)

^b Korea Centers for Disease Control and Prevention   (South Korea)

^c NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Alzheimer's disease; Korean; Population genetics; Prion protein gene; Single nucleotide polymorphism

Indexed keywords

PRION PROTEIN;

AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CODON; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; KOREA; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; POPULATION RESEARCH; PRIORITY JOURNAL;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; CHI-SQUARE DISTRIBUTION; DNA MUTATIONAL ANALYSIS; FEMALE; HUMANS; KOREA; MALE; POLYMORPHISM, GENETIC; PRIONS;

EID: 34249795501     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2007.01786.x     Document Type: Article

References (34)

1. Bertram L, Tanzi RE. The current status of Alzheimer's disease genetics: what do we tell the patients. Pharmacological Research 2004 50 : 71 74.
2. Combarros O, Alvarez-Arcaya A, Sanchez-Guerra M, Infante J, Berciano J. Candidate gene association studies in sporadic Alzheimer's disease. Dementia and Geriatric Cognitive Disorders 2002 14 : 41 54.
3. Farrer LA, Cupples LA, Haines JL, et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA 1997 278 : 1349 1356.
4. Esiri MM, Carter J, Ironside JW. Prion protein immunoreactivity in brain samples from an unselected autopsy population: findings in 200 consecutive cases. Neuropathology and Applied Neurobiology 2000 26 : 273 284.
5. Ferrer I, Blanco R, Carmona M, et al. Prion protein expression in senile plaques in Alzheimer's disease. Acta Neuropathologica 2001 101 : 49 56.
6. Kovacs GG, Head MW, Hegyi I, et al. Immunohistochemistry for the prion protein: comparison of different monoclonal antibodies in human prion disease subtypes. Brain Pathology 2002 12 : 1 11.
7. Hainfellner JA, Wanschitz J, Jellinger K, et al. Coexistence of Alzheimer-type neuropathology in Creutzfeldt-Jakob disease. Acta Neuropathologica 1998 96 : 116 122.
8. Miyazono M, Kitamoto T, Iwaki T, Tateishi J. Colocalization of prion protein and beta protein in the same amyloid plaques in patients with Gerstmann-Straussler syndrome. Acta Neuropathologica 1992 83 : 333 339.
9. Kovacs GG, Puopolo M, Ladogana A, et al. Genetic prion disease: the EUROCJD experience. Human Genetics 2005 118 : 166 174.
10. Mead S. Prion disease genetics. European Journal of Human Genetics 2006 14 : 273 281.
11. Jeong BH, Lee KH, Kim NH, et al. Association of sporadic Creutzfeldt-Jakob disease with homozygous genotypes at PRNP codons 129 and 219 in the Korean population. Neurogenetics 2005 6 : 229 232.
12. Palmer MS, Dryden AJ, Hughes JT, Collinge J. Homozygous prion protein genotype predisposes to sporadic Creutzfeldt-Jakob disease. Nature 1991 352 : 340 342.
13. Shibuya S, Higuchi J, Shin RW, Tateishi J, Kitamoto T. Codon 219 Lys allele of PRNP is not found in sporadic Creutzfeldt-Jakob disease. Annals of Neurology 1998 43 : 826 828.
14. Dermaut B, Croes EA, Rademakers R, et al. PRNP Val129 homozygosity increases risk for early-onset Alzheimer's disease. Annals of Neurology 2003 53 : 409 412.
15. Gacia M, Safranow K, Styczynska M, et al. Prion protein gene M129 allele is a risk factor for Alzheimer's disease. Journal of Neural Transmission 2006 113 : 1747 1751.
16. Golanska E, Hulas-Bigoszewska K, Rutkiewicz E, et al. Polymorphisms within the prion (PrP) and prion-like protein (Doppel) genes in AD. Neurology 2004 62 : 313 315.
17. Riemenschneider M, Klopp N, Xiang W, et al. Prion protein codon 129 polymorphism and risk of Alzheimer disease. Neurology 2004 63 : 364 366.
18. Casadei VM, Ferri C, Calabrese E, et al. Prion protein gene polymorphism and Alzheimer's disease: one modulatory trait of cognitive decline? Journal of Neurology, Neurosurgery, and Psychiatry 2001 71 : 279 280.
19. Combarros O, Sanchez-Guerra M, Llorca J, et al. Polymorphism at codon 129 of the prion protein gene is not associated with sporadic AD. Neurology 2000 55 : 593 595.
20. Li X, Rowland LP, Mitsumoto H, et al. Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia. Annals of Neurology 2005 58 : 858 864.
21. Ohkubo T, Sakasegawa Y, Asada T, et al. Absence of association between codon 129/219 polymorphisms of the prion protein gene and Alzheimer's disease in Japan. Annals of Neurology 2003 54 : 553 554.
22. McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984 34 : 939 944.
23. Jeong BH, Nam JH, Lee YJ, et al. Polymorphisms of the prion protein gene (PRNP) in a Korean population. Journal of Human Genetics 2004 49 : 319 324.
24. Del Bo R, Comi GP, Giorda R, et al. The 129 codon polymorphism of the prion protein gene influences earlier cognitive performance in Down syndrome subjects. Journal of Neurology 2003 250 : 688 692.
25. Scholz SW, Xiromerisiou G, Fung HC, et al. The human prion gene M129V polymorphism is not associated with idiopathic Parkinson's disease in three distinct populations. Neuroscience Letters 2006 395 : 227 229.
26. Croes EA, Dermaut B, Houwing-Duistermaat JJ, et al. Early cognitive decline is associated with prion protein codon 129 polymorphism. Annals of Neurology 2003 54 : 275 276.
27. Papassotiropoulos A, Wollmer MA, Aguzzi A, et al. The prion gene is associated with human long-term memory. Human Molecular Genetics 2005 14 : 2241 2246.
28. Rujescu D, Hartmann AM, Gonnermann C, Moller HJ, Giegling I. M129V variation in the prion protein may influence cognitive performance. Molecular Psychiatry 2003 8 : 937 941.
29. Tsai MT, Su YC, Chen YH, Chen CH. Lack of evidence to support the association of the human prion gene with schizophrenia. Molecular Psychiatry 2001 6 : 74 78.
30. Peoc'h K, Guerin C, Brandel JP, Launay JM, Laplanche JL. First report of polymorphisms in the prion-like protein gene (PRND): implications for human prion diseases. Neuroscience Letters 2000 286 : 144 148.
31. Schroder B, Franz B, Hempfling P, et al. Polymorphisms within the prion-like protein gene (Prnd) and their implications in human prion diseases, Alzheimer's disease and other neurological disorders. Human Genetics 2001 109 : 319 325.
32. Jeong BH, Kim NH, Choi EK, et al. Polymorphism at 3′ UTR +28 of the prion-like protein gene is associated with sporadic Creutzfeldt-Jakob disease. European Journal of Human Genetics 2005 13 : 1094 1097.
33. Jeong BH, Kim NH, Kim JI, Carp RI, Kim YS. Polymorphisms at codons 56 and 174 of the prion-like protein gene (PRND) are not associated with sporadic Creutzfeldt-Jakob disease. Journal of Human Genetics 2005 50 : 311 314.
34. Infante J, Llorca J, Rodero L, et al. Polymorphism at codon 174 of the prion-like protein gene is not associated with sporadic Alzheimer's disease. Neuroscience Letters 2002 332 : 213 215.