Acetaminophen-induced stimulation of MDR1 expression and activity in rat intestine and in LS 174T human intestinal cell line

Biochemical Pharmacology

Volumn 81, Issue 2, 2011, Pages 244-250

  Ghanem, Carolina I ^a,b   Arias, Agostina ^c   Novak, Analia ^b   Carpini, Griselda Delli ^b   Villanueva, Silvina ^c   Blazquez, Alba G ^d   Marin, Jose J G ^d   Mottino, Aldo D ^c   Rubio, Modesto C ^a  

^a Instituto de Investigaciones Farmacologicas   (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^c UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

^d UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

Acetaminophen; Digoxin; Intestine; LS 174T; MDR1; P glycoprotein

Indexed keywords

DIGOXIN; MULTIDRUG RESISTANCE PROTEIN 1; PARACETAMOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CYTOTOXICITY; DRUG ABSORPTION; DRUG EFFECT; DRUG EFFICACY; DUODENUM; HUMAN; HUMAN CELL; ILEUM; IMMUNOFLUORESCENCE MICROSCOPY; INTESTINE ABSORPTION; INTESTINE CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; WESTERN BLOTTING;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; BIOLOGICAL TRANSPORT; CARDIOTONIC AGENTS; CELL LINE; DIGOXIN; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HUMANS; INTESTINES; MALE; P-GLYCOPROTEIN; RATS; RATS, WISTAR;

EID: 78650178597     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.10.006     Document Type: Article

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