Levothyroxine up-regulates P-glycoprotein independent of the pregnane X receptor

Drug Metabolism and Disposition

Volumn 32, Issue 8, 2004, Pages 779-782

  Mitin, Tim ^a   Von Moltke, Lisa L ^a   Court, Michael H ^a   Greenblatt, David J ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; CELL PROTEIN; CYTOCHROME P450 3A4; GLYCOPROTEIN P; LEVOTHYROXINE; LIOTHYRONINE; MESSENGER RNA; PREGNANE X RECEPTOR; RIFAMPICIN; THYROID HORMONE; XENOBIOTIC AGENT;

ARTICLE; CANCER CELL CULTURE; CELL LEVEL; CELL STRAIN CACO 2; COLON CARCINOMA; CONSENSUS SEQUENCE; CONTROLLED STUDY; DRUG EFFECT; DRUG EXPOSURE; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; ENZYME LOCALIZATION; GENE CONTROL; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; UPREGULATION;

CACO-2 CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; P-GLYCOPROTEIN; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; THYROXINE; UP-REGULATION;

EUKARYOTA;

EID: 3242728359     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.32.8.779     Document Type: Article

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