Immunohistochemical detection of metallothionein in liver, duodenum and kidney after dietary copper-overload in rats

Histology and Histopathology

Volumn 13, Issue 3, 1998, Pages 627-633

  Fuentealba, I C ^a  

^a UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

Author keywords

Copper; Immunoperoxidase; Kidney; Metallothionein; Paneth cells

Indexed keywords

COPPER; METALLOTHIONEIN; MONOCLONAL ANTIBODY; PEROXIDASE; POLYCLONAL ANTIBODY; SCAVENGER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COPPER METABOLISM; DIETARY INTAKE; HEAVY METAL POISONING; IMMUNOHISTOCHEMISTRY; IMMUNOPEROXIDASE STAINING; INTESTINE ABSORPTION; INTESTINE EPITHELIUM CELL; KIDNEY TUBULE EPITHELIUM; LIVER CELL; MALE; NONHUMAN; PANETH CELL; RAT; URINARY EXCRETION;

ANIMALS; COPPER; DUODENUM; IMMUNOENZYME TECHNIQUES; KIDNEY; LIVER; MALE; METALLOTHIONEIN; MICE; RABBITS; RATS; RATS, WISTAR;

ANIMALIA; EQUUS CABALLUS; ORYCTOLAGUS CUNICULUS; RATTUS NORVEGICUS; RODENTIA;

EID: 0031816594     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Banerjee D., Onosaka S. and Cherian M.G. (1982). Immunohisto-chemical localization of metallothionein in cell nucleus and cytoplasm of rat liver and kidney. Toxicology 24, 95-105.
2. Brady F.O. (1982). The physiological function of metallothionein. Trends. Biochem. Sci. 7, 143-145.
3. 115 Cadmium: uptake and disappearance correlated with cadmium-binding protein synthesis. Biochem. Biophys. Res. Commun. 68, 858-866,
4. Cherian M.G. and Goyer R.A. (1978). Metallothioneins and their role in the metabolism and toxicity of metals. Life Sci. 23, 1-10.
5. Cousins R.J. (1985). Absorption, transport, and hepatic metabolism of copper and zinc: Special reference to metallothionein and ceruloplasmin. Physiol. Rev. 65, 238-309.
6. Danielson K.G., Ohi S. and Huang P.C. (1982). Immunochemical detection of metallothionein in specific epithelial cells of rat organs. Proc. Natl. Acad. Sci. USA 79, 2301-2304.