-
1
-
-
0027171266
-
Oxidants, antioxidants, and the degenerative diseases of aging
-
B.N. Ames, M.K. Shigenaga and T.M. Hagen (1993) Oxidants, antioxidants, and the degenerative diseases of aging. Froc NatlAcad Sci USA 90 7915-7922
-
(1993)
Froc NatlAcad Sci USA
, vol.90
, pp. 7915-7922
-
-
Ames, B.N.1
Shigenaga, M.K.2
Hagen, T.M.3
-
2
-
-
0029838022
-
L-deprenyl treatment in aged mice slightly increases life spans, and greatly reduces fecundity by aged males
-
J.R. Archer and D.E. Harrison (1996) L-deprenyl treatment in aged mice slightly increases life spans, and greatly reduces fecundity by aged males. J Gerontol A Biol Sci Med Sci 51 B448-B453
-
(1996)
J Gerontol A Biol Sci Med Sci
, vol.51
, pp. B448-B453
-
-
Archer, J.R.1
Harrison, D.E.2
-
4
-
-
0030177439
-
The uses of intraspecific variation in aging research
-
S.N. Austad (1996) The uses of intraspecific variation in aging research. Exp Gerontol 31 453-4463
-
(1996)
Exp Gerontol
, vol.31
, pp. 453-4463
-
-
Austad, S.N.1
-
5
-
-
0348047391
-
The retardation of aging by caloric restriction: its significance in the transgenic era
-
J.L. Barger, R.L. Walford and R. Weindruch (2003) The retardation of aging by caloric restriction: its significance in the transgenic era. Exp Gerontol 38 1343-1351
-
(2003)
Exp Gerontol
, vol.38
, pp. 1343-1351
-
-
Barger, J.L.1
Walford, R.L.2
Weindruch, R.3
-
6
-
-
0035936147
-
Extending the lifespan of long-lived mice
-
A. Bartke, J.C. Wright, J.A. Mattison, D.K. Ingram, R.A. Miller and G.S. Roth (2001) Extending the lifespan of long-lived mice. Nature 414 412
-
(2001)
Nature
, vol.414
, pp. 412
-
-
Bartke, A.1
Wright, J.C.2
Mattison, J.A.3
Ingram, D.K.4
Miller, R.A.5
Roth, G.S.6
-
7
-
-
0033039097
-
Revisiting the role of fat mass in the life exten-sion induced by caloric restriction. J
-
N. Barzilai and G. Gupta (1999) Revisiting the role of fat mass in the life exten-sion induced by caloric restriction. J. Gerontol 54 B89-B96
-
(1999)
Gerontol
, vol.54
, pp. B89-B96
-
-
Barzilai, N.1
Gupta, G.2
-
8
-
-
0030748533
-
Long-term treatment of male F344 rats with deprenyl: assess-ment of effects on longevity, behavior, and brain function
-
P.C. Bickford, C.E. Actams, S.J. Boyson, P. Curella, G.A. Gerhardt, C. Heron, et al. (1997) Long-term treatment of male F344 rats with deprenyl: assess-ment of effects on longevity, behavior, and brain function. Neurobiol Aging 18 309-318
-
(1997)
Neurobiol Aging
, vol.18
, pp. 309-318
-
-
Bickford, P.C.1
Actams, C.E.2
Boyson, S.J.3
Curella, P.4
Gerhardt, G.A.5
Heron, C.6
-
9
-
-
0037942739
-
Extended longevity in mice lacking the insulin receptor in adipose tissue
-
M. Blüher, B.B. Kahn and C.R. Kahn (2003) Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299 572-574
-
(2003)
Science
, vol.299
, pp. 572-574
-
-
Blüher, M.1
Kahn, B.B.2
Kahn, C.R.3
-
10
-
-
0018133545
-
Predicting death from behavioral test performance. J
-
J. Botwinick, R. West and N. Storandt (1978) Predicting death from behavioral test performance. J. Gerontol 33 755-762
-
(1978)
Gerontol
, vol.33
, pp. 755-762
-
-
Botwinick, J.1
West, R.2
Storandt, N.3
-
11
-
-
0025841730
-
Reduction in rate of occurrence of age related lesions in dietary restricted laboratory mice
-
R.T. Bronson and R.D. Lipman (1991) Reduction in rate of occurrence of age related lesions in dietary restricted laboratory mice. Growth Dev Aging 55 169-184
-
(1991)
Growth Dev Aging
, vol.55
, pp. 169-184
-
-
Bronson, R.T.1
Lipman, R.D.2
-
13
-
-
3042755617
-
Biomarkers of aging: from primitive organisms to humans
-
R.N. Butler, R. Sprott, H. Warner, J. Bland, R. Feuers, M. Forster, et al. (2004) Biomarkers of aging: from primitive organisms to humans. J Gerontol Biol Sci 59A 560-567
-
(2004)
J Gerontol Biol Sci
, vol.59A
, pp. 560-567
-
-
Butler, R.N.1
Sprott, R.2
Warner, H.3
Bland, J.4
Feuers, R.5
Forster, M.6
-
14
-
-
0028212032
-
The effect of a long term (6 months) treatment with (-) deprenyl on antioxidant enzyme activities in selective brain regions in old female Fischer 344 rats
-
M. Carrillo, K. Kitani, S. Kanai, Y. Sato, K. Miyasaka and G.O. Ivy (1994) The effect of a long term (6 months) treatment with (-) deprenyl on antioxidant enzyme activities in selective brain regions in old female Fischer 344 rats. Biochem Pharmacol 47 1333-1338
-
(1994)
Biochem Pharmacol
, vol.47
, pp. 1333-1338
-
-
Carrillo, M.1
Kitani, K.2
Kanai, S.3
Sato, Y.4
Miyasaka, K.5
Ivy, G.O.6
-
15
-
-
0032840413
-
Food restriction-like effects of dehydroepiandrosterone: decreased lymphocyte numbers and functions with increased apoptosis
-
F. Catalina, V. Kumar, L. Milewich and M. Bennett (1999) Food restriction-like effects of dehydroepiandrosterone: decreased lymphocyte numbers and functions with increased apoptosis. Proc Soc Exp Biol Med 221 326-335
-
(1999)
Proc Soc Exp Biol Med
, vol.221
, pp. 326-335
-
-
Catalina, F.1
Kumar, V.2
Milewich, L.3
Bennett, M.4
-
16
-
-
0027764702
-
Evolutionary mechanisms of senescence
-
B. Charlesworth (1993) Evolutionary mechanisms of senescence. Genetica 91 11-19
-
(1993)
Genetica
, vol.91
, pp. 11-19
-
-
Charlesworth, B.1
-
17
-
-
4644245973
-
Accelerated senes-cence prone mouse-8 shows early onset of deficits in spatial learning and memory in the radial six-arm water maze
-
G.H. Chen, Y.J. Wang, X.M. Wang and J.N. Zhou (2004) Accelerated senes-cence prone mouse-8 shows early onset of deficits in spatial learning and memory in the radial six-arm water maze. Physiol Behav 82 883-890
-
(2004)
Physiol Behav
, vol.82
, pp. 883-890
-
-
Chen, G.H.1
Wang, Y.J.2
Wang, X.M.3
Zhou, J.N.4
-
18
-
-
0032920969
-
Development and aging of primitive hematopoietic stem cells in BALB/cBy mice
-
J. Chen, C.M. Astle and D.E. Harrison (1999) Development and aging of primitive hematopoietic stem cells in BALB/cBy mice. Exp Hematol 27 928-935
-
(1999)
Exp Hematol
, vol.27
, pp. 928-935
-
-
Chen, J.1
Astle, C.M.2
Harrison, D.E.3
-
19
-
-
0034008968
-
Genetic regulation of primitive hematopoietic stem cell senescence
-
J. Chen, C.M. Astle and D.E. Harrison (2000) Genetic regulation of primitive hematopoietic stem cell senescence. Exp Hematol 28 442-450
-
(2000)
Exp Hematol
, vol.28
, pp. 442-450
-
-
Chen, J.1
Astle, C.M.2
Harrison, D.E.3
-
20
-
-
0142195931
-
Hematopoietic senescence is post-poned and hematopoietic stem cell function is enhanced by dietary restriction
-
J. Chen, C.M. Astle and D.E. Harrison (2003) Hematopoietic senescence is post-poned and hematopoietic stem cell function is enhanced by dietary restriction. Exp Hematol 31 1097-1103
-
(2003)
Exp Hematol
, vol.31
, pp. 1097-1103
-
-
Chen, J.1
Astle, C.M.2
Harrison, D.E.3
-
21
-
-
0026352187
-
Suggested guidelines for the housing and husbandry of rodents for aging studies
-
G. Clough (1991) Suggested guidelines for the housing and husbandry of rodents for aging studies. Neurobiol Aging 12 653-658
-
(1991)
Neurobiol Aging
, vol.12
, pp. 653-658
-
-
Clough, G.1
-
22
-
-
0014693213
-
Test-battery to measure aging-rate in man
-
A. Comfort (1969) Test-battery to measure aging-rate in man. Lancet 27 1411-1415
-
(1969)
Lancet
, vol.27
, pp. 1411-1415
-
-
Comfort, A.1
-
23
-
-
0034455827
-
Assessment of growth parameters and life span of GHR/BP gene-disrupted mice
-
K.T. Coschigano, D. Clemmons, L.L. Bellush and J.J. Kopchick (2000) Assessment of growth parameters and life span of GHR/BP gene-disrupted mice. Endocrinology 141 2608-2613
-
(2000)
Endocrinology
, vol.141
, pp. 2608-2613
-
-
Coschigano, K.T.1
Clemmons, D.2
Bellush, L.L.3
Kopchick, J.J.4
-
24
-
-
0041419437
-
Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span
-
K.T. Coschigano, A.N. Holland, M.E. Riders, E.O. List, A. Flyvbjerg and J.J. Kopchick (2003) Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span. Endocrinology 144 3799-3810
-
(2003)
Endocrinology
, vol.144
, pp. 3799-3810
-
-
Coschigano, K.T.1
Holland, A.N.2
Riders, M.E.3
List, E.O.4
Flyvbjerg, A.5
Kopchick, J.J.6
-
25
-
-
0002456078
-
Design and analysis of aging studies
-
Aging E.J. Masoro (Eds), New York: Oxford University Press
-
P.T. Costa Jr. and R.R. McCrae (1995) Design and analysis of aging studies. Aging E.J. Masoro (Eds) Handbook of physiology, Section 11 New York: Oxford University Press 25-36
-
(1995)
Handbook of physiology, Section 11
, pp. 25-36
-
-
Costa, P.T.1
McCrae, R.R.2
-
26
-
-
13744258936
-
The influence of genes on the aging process of mice: a statistical assessment of the genetics of aging
-
J.P. de Magalhaes, J.A. Cabrai and D. Magalhaes (2005) The influence of genes on the aging process of mice: a statistical assessment of the genetics of aging. Genetics 169 265-274
-
(2005)
Genetics
, vol.169
, pp. 265-274
-
-
de Magalhaes, J.P.1
Cabrai, J.A.2
Magalhaes, D.3
-
27
-
-
0026779471
-
Traits that influence longevity in mice: a second look
-
K.B. Dear, M Salazar, A.L. Watson, R.S. Gelman, R. Bronson and E.J. Yunis (1992) Traits that influence longevity in mice: a second look. Genetics 132 229-239
-
(1992)
Genetics
, vol.132
, pp. 229-239
-
-
Dear, K.B.1
Salazar, M.2
Watson, A.L.3
Gelman, R.S.4
Bronson, R.5
Yunis, E.J.6
-
28
-
-
0025087733
-
Differences in expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice
-
D.N. Ernst, M.V. Hobbs, B.E. Torbett, A.L. Glasebrook, M.A. Rehse, K. Bottomly, et al. (1990) Differences in expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice. J Immunol 145 1295-1302
-
(1990)
J Immunol
, vol.145
, pp. 1295-1302
-
-
Ernst, D.N.1
Hobbs, M.V.2
Torbett, B.E.3
Glasebrook, A.L.4
Rehse, M.A.5
Bottomly, K.6
-
29
-
-
0034051068
-
Age-associated increased interleukin-6 gene expression, late life diseases, and frailty
-
W.B. Ershler and E.T. Keller (2000) Age-associated increased interleukin-6 gene expression, late life diseases, and frailty. Ann Rev Med 51 245-270
-
(2000)
Ann Rev Med
, vol.51
, pp. 245-270
-
-
Ershler, W.B.1
Keller, E.T.2
-
30
-
-
0015529108
-
Lymphocytes, hormones and ageing
-
N. Fabris, W Pierpaoli and E. Sorkin (1972) Lymphocytes, hormones and ageing. Nature 240 557-559
-
(1972)
Nature
, vol.240
, pp. 557-559
-
-
Fabris, N.1
Pierpaoli, W.2
Sorkin, E.3
-
31
-
-
0032855098
-
Warning: the use of heterogeneous mice may seriously damage your research
-
M. Festing (1999) Warning: the use of heterogeneous mice may seriously damage your research. Neurbiol Aging 20 237-244
-
(1999)
Neurbiol Aging
, vol.20
, pp. 237-244
-
-
Festing, M.1
-
33
-
-
11444257052
-
Developmental origins of aging in brain and blood vessels: an overview
-
C.E. Finch (2005) Developmental origins of aging in brain and blood vessels: an overview. Neurobiol Aging 26 281-291
-
(2005)
Neurobiol Aging
, vol.26
, pp. 281-291
-
-
Finch, C.E.1
-
34
-
-
0019268979
-
Studies on ovarian-hypothalamic-pituitary interac-tions during reproductive aging in C57BL/6J mice
-
C.E. Finch, L.S. Felicio, K. Flurkey, D.M. Gee, C.V. Mobbs, J.F. Nelson and H.H. Osterburg (1980) Studies on ovarian-hypothalamic-pituitary interac-tions during reproductive aging in C57BL/6J mice. Peptides 1 163-175
-
(1980)
Peptides
, vol.1
, pp. 163-175
-
-
Finch, C.E.1
Felicio, L.S.2
Flurkey, K.3
Gee, D.M.4
Mobbs, C.V.5
Nelson, J.F.6
Osterburg, H.H.7
-
35
-
-
0021492228
-
Ovarian and steroidal influences on neuroendocrine aging processes in female rodents
-
C.E. Finch, L.S. Felicio, C.V. Mobbs and J.F. Nelson (1984) Ovarian and steroidal influences on neuroendocrine aging processes in female rodents. Endocrine Rev 5 467-497
-
(1984)
Endocrine Rev
, vol.5
, pp. 467-497
-
-
Finch, C.E.1
Felicio, L.S.2
Mobbs, C.V.3
Nelson, J.F.4
-
36
-
-
0024414994
-
Limitations of interpretation of age-related changes in hor-mone levels: illustration by effects of thyroid hormones on cardiac and skeletal muscle. J
-
J.R. Florini (1989) Limitations of interpretation of age-related changes in hor-mone levels: illustration by effects of thyroid hormones on cardiac and skeletal muscle. J. Gerontol 44 B107-B109
-
(1989)
Gerontol
, vol.44
, pp. B107-B109
-
-
Florini, J.R.1
-
37
-
-
0024448419
-
Skeletal muscle fiber types and myosin ATPase activity do not change with age or growth hormone administration
-
J.R. Florini and D.Z. Ewton (1989) Skeletal muscle fiber types and myosin ATPase activity do not change with age or growth hormone administration. J Gerontol 44 BUO-lll
-
(1989)
J Gerontol
, vol.44
, pp. BUO-lll
-
-
Florini, J.R.1
Ewton, D.Z.2
-
38
-
-
84884420650
-
Gerontology
-
G.D. Considine, PH. Kulik (Eds), 9th ed., New York: John Wiley & Sons, Inc
-
K. Flurkey (2001) Gerontology. G.D. Considine, PH. Kulik (Eds) Van Nostrand's scientific encyclopedia 9th ed. New York: John Wiley & Sons, Inc. 1614-1620
-
(2001)
Van Nostrand's scientific encyclopedia
, pp. 1614-1620
-
-
Flurkey, K.1
-
40
-
-
0006866013
-
Use of genetic models to investigate the hypophyseal regulation of senescence
-
D.E. Harrison (Eds), Caldwell, NJ: Telford Press
-
K. Flurkey and D.E. Harrison (1990) Use of genetic models to investigate the hypophyseal regulation of senescence. D.E. Harrison (Eds) enetic effects on aging II Caldwell, NJ: Telford Press 437-456
-
(1990)
enetic effects on aging II
, pp. 437-456
-
-
Flurkey, K.1
Harrison, D.E.2
-
41
-
-
0026505797
-
Memory T lymphocyte hypore-sponsiveness to non-cognate stimuli: a key factor in age-related immunodeficiency
-
K. Flurkey, M. Stadecker and R.A. Miller (1992) Memory T lymphocyte hypore-sponsiveness to non-cognate stimuli: a key factor in age-related immunodeficiency. Eur J Immunol 22 931-935
-
(1992)
Eur J Immunol
, vol.22
, pp. 931-935
-
-
Flurkey, K.1
Stadecker, M.2
Miller, R.A.3
-
42
-
-
0035811073
-
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production
-
K. Flurkey, J. Papaconstantinou, R.A. Miller and D.E. Harrison (2001) Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. Proc Natl Acad Sci U S A 98 6736-6741
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 6736-6741
-
-
Flurkey, K.1
Papaconstantinou, J.2
Miller, R.A.3
Harrison, D.E.4
-
43
-
-
0036132447
-
The Snell dwarf muta-tion Pitldw can increase life span in mice
-
K. Flurkey, J. Papaconstantinou and D.E. Harrison (2002) The Snell dwarf muta-tion Pitldw can increase life span in mice. Mech Ageing Dev 123 121-130
-
(2002)
Mech Ageing Dev
, vol.123
, pp. 121-130
-
-
Flurkey, K.1
Papaconstantinou, J.2
Harrison, D.E.3
-
44
-
-
84884422090
-
A new mouse model of extended female reproductive life span: effects of heterogeneity
-
(in press)
-
K.F. Flurkey, Y Brandvain, S.E. Klebanov, S.N. Austad, R.A. Miller, R. Yuan, et al. (2006) A new mouse model of extended female reproductive life span: effects of heterogeneity. J Gerontol (in press)
-
(2006)
J Gerontol
-
-
Flurkey, K.F.1
Brandvain, Y.2
Klebanov, S.E.3
Austad, S.N.4
Miller, R.A.5
Yuan, R.6
-
45
-
-
0013942563
-
The moulding of senescence by natural selection
-
W.D. Hamilton (1966) The moulding of senescence by natural selection. J Theor Biol 12 12-45
-
(1966)
J Theor Biol
, vol.12
, pp. 12-45
-
-
Hamilton, W.D.1
-
46
-
-
0142059585
-
Hormone levels and cataract scores as sex-specific, mid-life predictors of longevity in genetically heterogeneous mice
-
J.M. Harper, N. Wolf, A.T. Galecki, S.L. Pinkosky and R.A. Miller (2003) Hormone levels and cataract scores as sex-specific, mid-life predictors of longevity in genetically heterogeneous mice. Mech Ageing Dev 124 801-810
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 801-810
-
-
Harper, J.M.1
Wolf, N.2
Galecki, A.T.3
Pinkosky, S.L.4
Miller, R.A.5
-
47
-
-
2342665620
-
Body weight, hor-mones and T cell subsets as predictors of life span in genetically heterogeneous mice
-
J.M. Harper, A.T. Galecki, D.T. Burke and R.A. Miller (2004) Body weight, hor-mones and T cell subsets as predictors of life span in genetically heterogeneous mice. Mech Ageing Dev 125 381-390
-
(2004)
Mech Ageing Dev
, vol.125
, pp. 381-390
-
-
Harper, J.M.1
Galecki, A.T.2
Burke, D.T.3
Miller, R.A.4
-
48
-
-
0015505909
-
Normal function of transplanted mouse erythrocyte pre-cursors for 21 months beyond donor life spans
-
D.E. Harrison (1972) Normal function of transplanted mouse erythrocyte pre-cursors for 21 months beyond donor life spans. Nat New Biol 237 220-222
-
(1972)
Nat New Biol
, vol.237
, pp. 220-222
-
-
Harrison, D.E.1
-
49
-
-
0012304514
-
Cell and tissue transplantation: a means of studying the aging process
-
nd ed., New York: Van Nostrand Reinhold Co
-
D.E. Harrison (1985) Cell and tissue transplantation: a means of studying the aging process. C E. Finch, E.L. Schneider (Eds) Handbook of the biology of aging 2nd ed. New York: Van Nostrand Reinhold Co. 322-350
-
(1985)
Handbook of the biology of aging
, pp. 322-350
-
-
Harrison, D.E.1
-
50
-
-
0028113030
-
Potential misinterpretations using models of accelerated aging. J
-
D.E. Harrison (1994) Potential misinterpretations using models of accelerated aging. J. Gerontol Biol Sci 49 B245
-
(1994)
Gerontol Biol Sci
, vol.49
, pp. B245
-
-
Harrison, D.E.1
-
51
-
-
0031216231
-
Animal models showing “accelerated aging” are more likely to be useful for pathology than for mechanisms of aging
-
D.E. Harrison (1997) Animal models showing “accelerated aging” are more likely to be useful for pathology than for mechanisms of aging. Growth Dev Aging 61 167-168
-
(1997)
Growth Dev Aging
, vol.61
, pp. 167-168
-
-
Harrison, D.E.1
-
52
-
-
0017805239
-
Measurement of changes in mouse tail col-lagen with age: temperature dependence and procedural details
-
D.E. Harrison and J.R. Archer (1978) Measurement of changes in mouse tail col-lagen with age: temperature dependence and procedural details. Exp Gerontol 13 75-82
-
(1978)
Exp Gerontol
, vol.13
, pp. 75-82
-
-
Harrison, D.E.1
Archer, J.R.2
-
53
-
-
0021048571
-
Physiological assays for biological age in mice: relationship of collagen, renal function and longevity
-
D.E. Harrison and J.R. Archer (1983) Physiological assays for biological age in mice: relationship of collagen, renal function and longevity. Exp Aging Res 9 245-251
-
(1983)
Exp Aging Res
, vol.9
, pp. 245-251
-
-
Harrison, D.E.1
Archer, J.R.2
-
54
-
-
0023099924
-
Genetic effects on responses to food restric-tion in aging mice
-
D.E. Harrison and J.R. Archer (1987) Genetic effects on responses to food restric-tion in aging mice. J Nutr 117 376-382
-
(1987)
J Nutr
, vol.117
, pp. 376-382
-
-
Harrison, D.E.1
Archer, J.R.2
-
55
-
-
0023682911
-
Biomarkers of aging: tissue markers, future research needs, strategies, directions and priorities
-
D.E. Harrison and J.R. Archer (1988) Biomarkers of aging: tissue markers, future research needs, strategies, directions and priorities. Exp Gerontol 23 309-321
-
(1988)
Exp Gerontol
, vol.23
, pp. 309-321
-
-
Harrison, D.E.1
Archer, J.R.2
-
56
-
-
0020403099
-
Loss of stem cell repopulating ability upon transplantation: effects of donor age, cell number, and transplantation proce-dure. J
-
D.E. Harrison and C.M. Astle (1982) Loss of stem cell repopulating ability upon transplantation: effects of donor age, cell number, and transplantation proce-dure. J. Exp Med 156 1767-1779
-
(1982)
Exp Med
, vol.156
, pp. 1767-1779
-
-
Harrison, D.E.1
Astle, C.M.2
-
57
-
-
0030939638
-
Selection for maximum longevity in mice
-
D.E. Harrison and T.H. Roderick (1997) Selection for maximum longevity in mice. Exp Gerontol 32 65-78
-
(1997)
Exp Gerontol
, vol.32
, pp. 65-78
-
-
Harrison, D.E.1
Roderick, T.H.2
-
58
-
-
0017833969
-
Tail collagen aging in mice of thirteen different genotypes and two species: relationship to biological age
-
D.E. Harrison, J.R. Archer, G.A. Sacher and KM. Boyce (1978) Tail collagen aging in mice of thirteen different genotypes and two species: relationship to biological age. Exp Gerontol 13 63-73
-
(1978)
Exp Gerontol
, vol.13
, pp. 63-73
-
-
Harrison, D.E.1
Archer, J.R.2
Sacher, G.A.3
Boyce, K.M.4
-
59
-
-
0020384525
-
The effect of hypophysectomy on thymic aging in mice
-
D.E. Harrison, J.R. Archer and C.M. Astle (1982) The effect of hypophysectomy on thymic aging in mice. J Immunol 129 2673-2677
-
(1982)
J Immunol
, vol.129
, pp. 2673-2677
-
-
Harrison, D.E.1
Archer, J.R.2
Astle, C.M.3
-
60
-
-
0001001689
-
Effects of food restriction on aging: separation of food intake and adiposity
-
D.E. Harrison, J.R. Archer and C.M. Astle (1984) Effects of food restriction on aging: separation of food intake and adiposity. Proc NatlAcad Sci USA 81 1835-1838
-
(1984)
Proc NatlAcad Sci USA
, vol.81
, pp. 1835-1838
-
-
Harrison, D.E.1
Archer, J.R.2
Astle, C.M.3
-
61
-
-
0024380947
-
Effects of age on transplantable primitive immuno-hematopoietic stem cell (PSC) numbers and functions
-
D.E. Harrison, C.M. Astle and M. Stone (1989) Effects of age on transplantable primitive immuno-hematopoietic stem cell (PSC) numbers and functions. J Immunol 142 3833-3840
-
(1989)
J Immunol
, vol.142
, pp. 3833-3840
-
-
Harrison, D.E.1
Astle, C.M.2
Stone, M.3
-
62
-
-
0343830627
-
Genes regulate effects of dietary restriction
-
L. Fishbein (Eds), New York: Springer-Verlag
-
D.E. Harrison, J.R. Archer and B. Kent (1991) Genes regulate effects of dietary restriction. L. Fishbein (Eds) Biological effects of dietary restriction New York: Springer-Verlag 264-286
-
(1991)
Biological effects of dietary restriction
, pp. 264-286
-
-
Harrison, D.E.1
Archer, J.R.2
Kent, B.3
-
63
-
-
0027893247
-
Primitive hemo-poietic stem cells: direct assay of most productive populations by competitive repopulation with simple binomial, correlation, and covariance calculations
-
D.E. Harrison, CT. Jordan, R.K. Zhong and C.M. Astle (1993) Primitive hemo-poietic stem cells: direct assay of most productive populations by competitive repopulation with simple binomial, correlation, and covariance calculations. Exp Hematol 21 206-219
-
(1993)
Exp Hematol
, vol.21
, pp. 206-219
-
-
Harrison, D.E.1
Jordan, C.T.2
Zhong, R.K.3
Astle, C.M.4
-
64
-
-
4544377929
-
Accelerating aging by mouse reverse genetics: a rational approach to understanding longevity
-
P. Hasty and J. Vijg (2004) Accelerating aging by mouse reverse genetics: a rational approach to understanding longevity. Aging Cell 3 55
-
(2004)
Aging Cell
, vol.3
, pp. 55
-
-
Hasty, P.1
Vijg, J.2
-
65
-
-
0023628408
-
Increase in life expectancy for mice fed diethyl-hydroxylamine (DEHA)
-
J. Heicklen and E. Brown (1987) Increase in life expectancy for mice fed diethyl-hydroxylamine (DEHA). J Gerontol 42 674-680
-
(1987)
J Gerontol
, vol.42
, pp. 674-680
-
-
Heicklen, J.1
Brown, E.2
-
66
-
-
0031749354
-
Mortality and biomarkers of aging in heterogeneous stock (HS) mice. J
-
D.A. Heller, KM. Ahern, J.T. Stout and G.E. McClearn (1998) Mortality and biomarkers of aging in heterogeneous stock (HS) mice. J. Gerontol 53A B217-B230
-
(1998)
Gerontol
, vol.53A
, pp. B217-B230
-
-
Heller, D.A.1
Ahern, K.M.2
Stout, J.T.3
McClearn, G.E.4
-
67
-
-
0000521753
-
Exercise
-
E.J. Masoro (Eds), New York: Oxford University Press, Section 11, Aging
-
J.O. Holloszy and W.M. Kohrt (1995) Exercise. E.J. Masoro (Eds) Handbook of physiology New York: Oxford University Press 633-666. Section 11, Aging
-
(1995)
Handbook of physiology
, pp. 633-666
-
-
Holloszy, J.O.1
Kohrt, W.M.2
-
69
-
-
0021080969
-
Towards the behavioral assessment of biological aging in the laboratory mouse: concepts, terminology and objectives
-
D.K. Ingram (1983) Towards the behavioral assessment of biological aging in the laboratory mouse: concepts, terminology and objectives. Exp Aging Res 9 225-238
-
(1983)
Exp Aging Res
, vol.9
, pp. 225-238
-
-
Ingram, D.K.1
-
70
-
-
0022897807
-
Assessing the predictive validity of psy-chomotor tests as measures of biological age in mice
-
D.K. Ingram and M.A. Reynolds (1986) Assessing the predictive validity of psy-chomotor tests as measures of biological age in mice. Exp Aging Res 12 155-162
-
(1986)
Exp Aging Res
, vol.12
, pp. 155-162
-
-
Ingram, D.K.1
Reynolds, M.A.2
-
71
-
-
0020362754
-
Physiological and behavioral correlates of lifespan in aged C57BL/6J mice
-
D.K. Ingram, J.R. Archer, D.E. Harrison and M.A. Reynolds (1982) Physiological and behavioral correlates of lifespan in aged C57BL/6J mice. Exp Gerontol 17 295-303
-
(1982)
Exp Gerontol
, vol.17
, pp. 295-303
-
-
Ingram, D.K.1
Archer, J.R.2
Harrison, D.E.3
Reynolds, M.A.4
-
72
-
-
0036141752
-
Mouse loci asso-ciated with life span exhibit sex-specific and epistatic effects
-
A.U. Jackson, A.T. Galecki, D.T. Burke and R.A. Miller (2002) Mouse loci asso-ciated with life span exhibit sex-specific and epistatic effects. J Gerontol 57 B9-B15
-
(2002)
J Gerontol
, vol.57
, pp. B9-B15
-
-
Jackson, A.U.1
Galecki, A.T.2
Burke, D.T.3
Miller, R.A.4
-
73
-
-
0028260335
-
(-) Deprenyl increases the lifespan as well as activities of Superoxide dismutase and catalase but not of glutathione peroxidase in selective brain regions in Fischer rats
-
K. Kitani, S. Kanai, M.C. Carrillo and G.O. Ivy (1994) (-) Deprenyl increases the lifespan as well as activities of Superoxide dismutase and catalase but not of glutathione peroxidase in selective brain regions in Fischer rats. Ann N Y Acad Sci 717 72-78
-
(1994)
Ann N Y Acad Sci
, vol.717
, pp. 72-78
-
-
Kitani, K.1
Kanai, S.2
Carrillo, M.C.3
Ivy, G.O.4
-
74
-
-
0018561650
-
Age-related changes in the immune system of mice of eight medium and long-lived strains and hybrids. I. Organ, cellular and activity changes
-
M.M.B. Kay, J. Mendoza, J. Diven, T. Denton, N. Union and M. Lajiness (1979) Age-related changes in the immune system of mice of eight medium and long-lived strains and hybrids. I. Organ, cellular and activity changes. Mech Ageing Dev 11 295-346
-
(1979)
Mech Ageing Dev
, vol.11
, pp. 295-346
-
-
Kay, M.M.B.1
Mendoza, J.2
Diven, J.3
Denton, T.4
Union, N.5
Lajiness, M.6
-
75
-
-
0036132118
-
Optimizing detection of QTLs retarding aging: choice of statistical model and animal requirements
-
S. Klebanov and D.E. Harrison (2002) Optimizing detection of QTLs retarding aging: choice of statistical model and animal requirements. Mech Ageing Dev 123 131-144
-
(2002)
Mech Ageing Dev
, vol.123
, pp. 131-144
-
-
Klebanov, S.1
Harrison, D.E.2
-
76
-
-
0035680580
-
Maximum life spans in mice are extended by wild strain alleles
-
S. Klebanov, C.M. Astle, T.H. Roderick, K. Flurkey, J.R. Archer, J. Chen and D.E. Harrison (2001) Maximum life spans in mice are extended by wild strain alleles. Exp Biol Med 226 854-859
-
(2001)
Exp Biol Med
, vol.226
, pp. 854-859
-
-
Klebanov, S.1
Astle, C.M.2
Roderick, T.H.3
Flurkey, K.4
Archer, J.R.5
Chen, J.6
Harrison, D.E.7
-
77
-
-
0035213017
-
Heritability of life span in mice and its implication for direct and indirect selection for longevity
-
S. Klebanov, K. Flurkey, T.H. Roderick, J.R. Archer, M.C. Astle, J. Chen and D.E. Harrison (2001) Heritability of life span in mice and its implication for direct and indirect selection for longevity. Genetica 110 209-218
-
(2001)
Genetica
, vol.110
, pp. 209-218
-
-
Klebanov, S.1
Flurkey, K.2
Roderick, T.H.3
Archer, J.R.4
Astle, M.C.5
Chen, J.6
Harrison, D.E.7
-
78
-
-
22544449911
-
Adipose tissue transplantation protects ob/ob mice from obesity, nor-malizes insulin sensitivity and restores fertility
-
S. Klebanov, M.C. Astle, O. DeSimone, V. Ablamunits and D.E. Harrison (2005) Adipose tissue transplantation protects ob/ob mice from obesity, nor-malizes insulin sensitivity and restores fertility. J Endocrinol 186 203-211
-
(2005)
J Endocrinol
, vol.186
, pp. 203-211
-
-
Klebanov, S.1
Astle, M.C.2
DeSimone, O.3
Ablamunits, V.4
Harrison, D.E.5
-
79
-
-
0024267460
-
The striatal dopamine dependency of life span in male rats: longevity study with (-) deprenyl
-
J. Knoll (1988) The striatal dopamine dependency of life span in male rats: longevity study with (-) deprenyl. Mech Ageing Dev 46 237-262
-
(1988)
Mech Ageing Dev
, vol.46
, pp. 237-262
-
-
Knoll, J.1
-
80
-
-
0028834176
-
The role of thymus in the aging of Th cell subpopulations and age-associated alteration of cytokine production by these cells
-
C. Kurashima, M. Utsuyama, M. Kasai, S.A. Ishijima, A. Konno and K. Hirokawa (1995) The role of thymus in the aging of Th cell subpopulations and age-associated alteration of cytokine production by these cells. Int Immunol 7 97-104
-
(1995)
Int Immunol
, vol.7
, pp. 97-104
-
-
Kurashima, C.1
Utsuyama, M.2
Kasai, M.3
Ishijima, S.A.4
Konno, A.5
Hirokawa, K.6
-
81
-
-
0036734833
-
Evidence that brain-derived neu-rotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice
-
J. Lee, W. Duan and M.P. Mattson (2002) Evidence that brain-derived neu-rotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. J Neurochem 82 1367-1375
-
(2002)
J Neurochem
, vol.82
, pp. 1367-1375
-
-
Lee, J.1
Duan, W.2
Mattson, M.P.3
-
82
-
-
0024475129
-
Pgp-lhi lymphocytes accumulate with age in mice and respond poorly to concanavalin A
-
A. Lerner, T. Yamada and R.A. Miller (1989) Pgp-lhi lymphocytes accumulate with age in mice and respond poorly to concanavalin A. EurJ Immunol 19 977-982
-
(1989)
EurJ Immunol
, vol.19
, pp. 977-982
-
-
Lerner, A.1
Yamada, T.2
Miller, R.A.3
-
83
-
-
0347416781
-
Genetic mouse models of extended life span
-
H. Liang, E.J. Masoro, J.F. Nelson, R. Strong, C.A. McMahan and A. Richardson (2003) Genetic mouse models of extended life span. Exp Gerontol 38 1353-1364
-
(2003)
Exp Gerontol
, vol.38
, pp. 1353-1364
-
-
Liang, H.1
Masoro, E.J.2
Nelson, J.F.3
Strong, R.4
McMahan, C.A.5
Richardson, A.6
-
84
-
-
0032527920
-
Disease incidence and longevity are unaltered by dietary antioxidant supplementation initiated during middle age in C57BL/6 mice
-
R.D. Lipman, R.T. Bronson, D. Wu, D.E. Smith, R. Prior, G. Cao, et al. (1998) Disease incidence and longevity are unaltered by dietary antioxidant supplementation initiated during middle age in C57BL/6 mice. Mech Ageing Dev 103 269-284
-
(1998)
Mech Ageing Dev
, vol.103
, pp. 269-284
-
-
Lipman, R.D.1
Bronson, R.T.2
Wu, D.3
Smith, D.E.4
Prior, R.5
Cao, G.6
-
86
-
-
0033377755
-
Effects of genotype and diet on age-related lesions in ad libitum fed and calorie-restricted F344, BN, and BNF3F1 rats
-
R.D. Lipman, G.E. Dallai and R.T. Bronson (1999) Effects of genotype and diet on age-related lesions in ad libitum fed and calorie-restricted F344, BN, and BNF3F1 rats. J Gerontol A Biol Sci Med Sci 54 B478-B491
-
(1999)
J Gerontol A Biol Sci Med Sci
, vol.54
, pp. B478-B491
-
-
Lipman, R.D.1
Dallai, G.E.2
Bronson, R.T.3
-
87
-
-
0000977248
-
Selection for delayed senescence in
-
L.S. Luckinbill, R. Arking, M.J. Clare, W.C. Cirocco and S.A. Buck (1984) Selection for delayed senescence in. Drosophila melanogaster. Evolution 38 996-1003
-
(1984)
Drosophila melanogaster. Evolution
, vol.38
, pp. 996-1003
-
-
Luckinbill, L.S.1
Arking, R.2
Clare, M.J.3
Cirocco, W.C.4
Buck, S.A.5
-
89
-
-
0022048716
-
Does food restriction retard aging by reducing metabolic rate?
-
R.J.M. McCarter, E.J. Masoro and B.P. Yu (1985) Does food restriction retard aging by reducing metabolic rate? Am J Physiol 248 488-490
-
(1985)
Am J Physiol
, vol.248
, pp. 488-490
-
-
McCarter, R.J.M.1
Masoro, E.J.2
Yu, B.P.3
-
90
-
-
0032878512
-
Genes as gerontological variables: uni-form genotypes
-
G.E. McClearn and S.M. Hof er S.M. (1999) Genes as gerontological variables: uni-form genotypes. Neurobiol Aging 20 95-104
-
(1999)
Neurobiol Aging
, vol.20
, pp. 95-104
-
-
McClearn, G.E.1
Hof, S.M.2
-
91
-
-
0032879787
-
Genes as gerontological variables: genet-ically heterogeneous stocks and complex systems
-
G.E. McClearn and S.M. Hofer (1999) Genes as gerontological variables: genet-ically heterogeneous stocks and complex systems. Neurobiol Aging 20 147-156
-
(1999)
Neurobiol Aging
, vol.20
, pp. 147-156
-
-
McClearn, G.E.1
Hofer, S.M.2
-
92
-
-
0017840139
-
Genetic syndromes in man with potential relevance to the pathology of aging
-
D. Bergsma, D.E. Harrison (Eds), New York: Alan R. Liss, Inc., Section I
-
G.N. Martin (1978) Genetic syndromes in man with potential relevance to the pathology of aging. D. Bergsma, D.E. Harrison (Eds) Genetic effect on aging New York: Alan R. Liss, Inc. 5-39. Section I
-
(1978)
Genetic effect on aging
, pp. 5-39
-
-
Martin, G.N.1
-
93
-
-
0021245012
-
Nutrition as a modulator of the aging process
-
E.J. Masoro (1984) Nutrition as a modulator of the aging process. The Physiologist 27 98-101
-
(1984)
The Physiologist
, vol.27
, pp. 98-101
-
-
Masoro, E.J.1
-
94
-
-
0026341970
-
Use of rodents as models for the study of “normal aging”: conceptual and practical issues
-
E.J. Masoro (1991) Use of rodents as models for the study of “normal aging”: conceptual and practical issues. Neurobiol Aging 12 639-643
-
(1991)
Neurobiol Aging
, vol.12
, pp. 639-643
-
-
Masoro, E.J.1
-
95
-
-
0002546845
-
Aging: current concepts
-
E.J. Masoro (Eds), New York: Oxford University Press, Section 11, Aging
-
E.J. Masoro (1995) Aging: current concepts. E.J. Masoro (Eds) Handbook of physiology New York: Oxford University Press 3-24. Section 11, Aging
-
(1995)
Handbook of physiology
, pp. 3-24
-
-
Masoro, E.J.1
-
96
-
-
0026526384
-
Dietary restriction alters characteristics of glucose fuel use. J
-
E.J. Masoro, R.J. McCarter, M.S. Katz and C.A. McMahan (1992) Dietary restriction alters characteristics of glucose fuel use. J. Gerontol 47 B202-B208
-
(1992)
Gerontol
, vol.47
, pp. B202-B208
-
-
Masoro, E.J.1
McCarter, R.J.2
Katz, M.S.3
McMahan, C.A.4
-
97
-
-
0036304650
-
Modification of brain aging and neurodegenerative disorders by genes, and diet restriction
-
M.P. Mattson, S.L. Chan and W. Duan (2002) Modification of brain aging and neurodegenerative disorders by genes, and diet restriction. Physiol Rev 82 637-672
-
(2002)
Physiol Rev
, vol.82
, pp. 637-672
-
-
Mattson, M.P.1
Chan, S.L.2
Duan, W.3
-
98
-
-
0004220736
-
-
London: H.K. Lewis, (Monograph of lecture delivered at University College, London, 6 Dec 1951)
-
P.B. Medawar (1952) An unsolved problem of biology. London: H.K. Lewis (Monograph of lecture delivered at University College, London, 6 Dec 1951)
-
(1952)
An unsolved problem of biology
-
-
Medawar, P.B.1
-
99
-
-
0025050782
-
Maintenance on L-deprenyl prolongs life in aged male rats
-
N.W. Milgram, R.J. Racine, P. Nellis, A. Mendonca and G.O. Ivy (1990) Maintenance on L-deprenyl prolongs life in aged male rats. Life Sci 47 415-420
-
(1990)
Life Sci
, vol.47
, pp. 415-420
-
-
Milgram, N.W.1
Racine, R.J.2
Nellis, P.3
Mendonca, A.4
Ivy, G.O.5
-
100
-
-
0000697659
-
Immune system
-
E.J. Masoro (Eds), New York: Oxford University Press, Section 11, Aging
-
R.A. Miller (1995) Immune system. E.J. Masoro (Eds) Handbook of physiology New York: Oxford University Press 555-590. Section 11, Aging
-
(1995)
Handbook of physiology
, pp. 555-590
-
-
Miller, R.A.1
-
101
-
-
0035074534
-
Biomarkers of aging: prediction of longevity by using age-sensitive T-cell subset determinations in a middle-aged, geneti-cally hetrogenous mouse population
-
R.A. Miller (2001) Biomarkers of aging: prediction of longevity by using age-sensitive T-cell subset determinations in a middle-aged, geneti-cally hetrogenous mouse population. J Gerontol A Biol Med Sci 56 B180-B186
-
(2001)
J Gerontol A Biol Med Sci
, vol.56
, pp. B180-B186
-
-
Miller, R.A.1
-
102
-
-
4444327055
-
'Accelerated aging': a primrose path to insight?
-
R.A. Miller (2004) 'Accelerated aging': a primrose path to insight? Aging Cell 3 47-51
-
(2004)
Aging Cell
, vol.3
, pp. 47-51
-
-
Miller, R.A.1
-
103
-
-
84855413338
-
Principles of animal use for gerontological research
-
P.M. Conn (Eds), New York: Elsevier, Chapter 3
-
R.A. Miller (2006) Principles of animal use for gerontological research. P.M. Conn (Eds) Handbook for models of human aging New York: Elsevier 21-31. Chapter 3
-
(2006)
Handbook for models of human aging
, pp. 21-31
-
-
Miller, R.A.1
-
104
-
-
0032777536
-
Lifelong treatment with oral DHEA sulfate does not preserve immune function, prevent disease, or improve survival in genetically heterogeneous mice
-
R.A. Miller and C. Chrisp (1999) Lifelong treatment with oral DHEA sulfate does not preserve immune function, prevent disease, or improve survival in genetically heterogeneous mice. J Am Geriatr Soc 47 960-966
-
(1999)
J Am Geriatr Soc
, vol.47
, pp. 960-966
-
-
Miller, R.A.1
Chrisp, C.2
-
105
-
-
0036681649
-
T cell subset patterns that predict resistance to spontaneous lymphoma, mammary adenocarcinoma, and fibrosarcoma in mice
-
R.A. Miller and C. Chrisp (2002) T cell subset patterns that predict resistance to spontaneous lymphoma, mammary adenocarcinoma, and fibrosarcoma in mice. J Immunol 169 1619-1625
-
(2002)
J Immunol
, vol.169
, pp. 1619-1625
-
-
Miller, R.A.1
Chrisp, C.2
-
106
-
-
0034053957
-
Principles of animal use for gerontological research. J
-
R.A. Miller and N.L. Nadon (2000) Principles of animal use for gerontological research. J. Gerontol A Biol Sci Med Sci 55A B117-B123
-
(2000)
Gerontol A Biol Sci Med Sci
, vol.55A
, pp. B117-B123
-
-
Miller, R.A.1
Nadon, N.L.2
-
107
-
-
0031031497
-
Candidate biomarkers of aging: age-sensitive indices of immune and muscle function covary in genetically heterogeneous mice
-
R.A. Miller, F. Bookstein, J. Van der Meulen, S. Engle, J. Kim, L. Mullins and J. Faulkner (1997) Candidate biomarkers of aging: age-sensitive indices of immune and muscle function covary in genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci 52 B39-B47
-
(1997)
J Gerontol A Biol Sci Med Sci
, vol.52
, pp. B39-B47
-
-
Miller, R.A.1
Bookstein, F.2
Van der Meulen, J.3
Engle, S.4
Kim, J.5
Mullins, L.6
Faulkner, J.7
-
108
-
-
0032877158
-
Exotic mice as models for aging research, polemic and prospectus
-
R.A. Miller, S.N. Austad, D. Burke, C. Chrisp, R. Dysko, et al. (1999) Exotic mice as models for aging research, polemic and prospectus. Neurobiol Aging 20 217-231
-
(1999)
Neurobiol Aging
, vol.20
, pp. 217-231
-
-
Miller, R.A.1
Austad, S.N.2
Burke, D.3
Chrisp, C.4
Dysko, R.5
-
109
-
-
0036656427
-
Longer life spans and delayed maturation in wild-derived mice
-
R.A. Miller, J.M. Harper, R.C. Dysko, S.J. Durkee and S.N. Austad (2002) Longer life spans and delayed maturation in wild-derived mice. Exp Biol Med 227 500-508
-
(2002)
Exp Biol Med
, vol.227
, pp. 500-508
-
-
Miller, R.A.1
Harper, J.M.2
Dysko, R.C.3
Durkee, S.J.4
Austad, S.N.5
-
110
-
-
0034893757
-
Lack of an effect of vitamin E on lifespan of mice
-
A.A. Morley and K.J. Trainor (2001) Lack of an effect of vitamin E on lifespan of mice. Biogerontology 2 109-112
-
(2001)
Biogerontology
, vol.2
, pp. 109-112
-
-
Morley, A.A.1
Trainor, K.J.2
-
111
-
-
0343005385
-
Disease patterns in aging inbred mouse strains: interaction of genetics and environment
-
D. Bergsma, D.E. Harrison (Eds), New York: Alan R. Liss
-
D.D. Myers (1978) Disease patterns in aging inbred mouse strains: interaction of genetics and environment. D. Bergsma, D.E. Harrison (Eds) Genetic effects on aging New York: Alan R. Liss 41-53
-
(1978)
Genetic effects on aging
, pp. 41-53
-
-
Myers, D.D.1
-
112
-
-
6944248738
-
Maintaining aged rodents for biogerontology research
-
N. Nadon (2004) Maintaining aged rodents for biogerontology research. Lab Anim 33 36-41
-
(2004)
Lab Anim
, vol.33
, pp. 36-41
-
-
Nadon, N.1
-
113
-
-
84884448733
-
Prevention of AKR leukemia by thymectomy at varying ages
-
K. Nakakuki, H. Shisa and Y. Nishizuka (1967) Prevention of AKR leukemia by thymectomy at varying ages. Acta Haemat 38 317
-
(1967)
Acta Haemat
, vol.38
, pp. 317
-
-
Nakakuki, K.1
Shisa, H.2
Nishizuka, Y.3
-
114
-
-
20044366932
-
Pharmacogenetic analysis of rosiglitazone-induced hepatosteatosis in new mouse models of type 2 diabetes
-
HJ. Pan, P. Reifsnyder, D.E. Vance, Q. Xiao and E.H. Leiter (2005) Pharmacogenetic analysis of rosiglitazone-induced hepatosteatosis in new mouse models of type 2 diabetes. Diabetes 54 1854-1862
-
(2005)
Diabetes
, vol.54
, pp. 1854-1862
-
-
Pan, H.J.1
Reifsnyder, P.2
Vance, D.E.3
Xiao, Q.4
Leiter, E.H.5
-
115
-
-
0027469970
-
Optimality, mutation and the evolution of ageing
-
L. Partridge and N.H. Barton (1993) Optimality, mutation and the evolution of ageing. Nature 362 305-311
-
(1993)
Nature
, vol.362
, pp. 305-311
-
-
Partridge, L.1
Barton, N.H.2
-
116
-
-
0028013595
-
Selecting animal models of human aging. Inbred strains often exhibit less biological uniformity than Fl hybrids
-
J.P. Phelan and S.N. Austad (1994) Selecting animal models of human aging. Inbred strains often exhibit less biological uniformity than Fl hybrids. J Gerontol 4 Bl-Bll
-
(1994)
J Gerontol
, vol.4
, pp. Bl-Bll
-
-
Phelan, J.P.1
Austad, S.N.2
-
117
-
-
20044394908
-
Use of a dense single nucleotide polymorphism map for in silico mapping in the mouse
-
Epub 2004 Nov 9
-
M.T. Pletcher, P. McClurg, S. Batalov, A.I. Su, S.W. Barnes and E. Lagler E.et al (2004) Use of a dense single nucleotide polymorphism map for in silico mapping in the mouse. PLoS Biol 2 e393 Epub 2004 Nov 9
-
(2004)
PLoS Biol 2
, vol.e393
-
-
Pletcher, M.T.1
McClurg, P.2
Batalov, S.3
Su, A.I.4
Barnes, S.W.5
Lagler, E.6
-
118
-
-
0026718001
-
Age-related changes in LFA-1 expression, cell adhesion, and PHA-induced proliferation by lymphocytes from senescence-accelerated mouse (SAM) -P/8 and SAM-R/1 substrains
-
D.C. Powers, J.E. Morley and J.F. Flood (1992) Age-related changes in LFA-1 expression, cell adhesion, and PHA-induced proliferation by lymphocytes from senescence-accelerated mouse (SAM) -P/8 and SAM-R/1 substrains. Cell Immunol 141 444-456
-
(1992)
Cell Immunol
, vol.141
, pp. 444-456
-
-
Powers, D.C.1
Morley, J.E.2
Flood, J.F.3
-
119
-
-
0033119046
-
Dietary intervention at middle-age: caloric restriction but not dehydroepiandrosterone sulfate increases life span and lifetime cancer incidence in mice
-
T.D. Pugh, T.D. Oberley and R. Weindruch (1999) Dietary intervention at middle-age: caloric restriction but not dehydroepiandrosterone sulfate increases life span and lifetime cancer incidence in mice. Cancer Res 59 1642-1648
-
(1999)
Cancer Res
, vol.59
, pp. 1642-1648
-
-
Pugh, T.D.1
Oberley, T.D.2
Weindruch, R.3
-
120
-
-
4243843266
-
The evidence for pituitary and thyroid control of aging: is age reversal a myth or reality? The search for a “death hormone
-
W. Regelson, F.M. Sinex (Eds), New York: Allen R. Liss, Inc
-
W. Regelson (1983) The evidence for pituitary and thyroid control of aging: is age reversal a myth or reality? The search for a “death hormone. W. Regelson, F.M. Sinex (Eds) Intervention in the aging process, Part B: Basic research and preclinical screening New York: Allen R. Liss, Inc. 3-52
-
(1983)
Intervention in the aging process, Part B: Basic research and preclinical screening
, pp. 3-52
-
-
Regelson, W.1
-
121
-
-
0001557938
-
Selection for radiation resistance in mice
-
T.H. Roderick (1963) Selection for radiation resistance in mice. Genetics 48 205-216
-
(1963)
Genetics
, vol.48
, pp. 205-216
-
-
Roderick, T.H.1
-
123
-
-
0000977247
-
Laboratory evolution of postponed senescence in
-
M.R. Rose (1984) Laboratory evolution of postponed senescence in. Drosophila melanogaster. Evolution 38 1004-1010
-
(1984)
Drosophila melanogaster. Evolution
, vol.38
, pp. 1004-1010
-
-
Rose, M.R.1
-
125
-
-
0002598664
-
Lifespan and aging patterns
-
nd ed., New York: Dover Publications, Inc
-
E.S. Russell (1966) Lifespan and aging patterns. E.L. Green (Eds) Biology of the laboratory mouse 2nd ed. New York: Dover Publications, Inc. 511-520
-
(1966)
Biology of the laboratory mouse
, pp. 511-520
-
-
Russell, E.S.1
-
126
-
-
0011057941
-
Genetic considerations in the selection of rodent species and strains for research on aging
-
D.C. Gibson (Eds), U.S. Gov. Printing Office No. 1746-0010
-
E.S. Russell (1972) Genetic considerations in the selection of rodent species and strains for research on aging. D.C. Gibson (Eds) In Development of the rodent as a model system of aging NIH, NICHD Pub. No. 72-121 U.S. Gov. Printing Office No. 1746-0010 33-53
-
(1972)
In Development of the rodent as a model system of aging NIH, NICHD Pub. No. 72-121
, pp. 33-53
-
-
Russell, E.S.1
-
127
-
-
0017844690
-
Longevity, aging and comparative cellular and molecular biology of the house mouse, Mus musculus, and the white-footed mouse, Peromyscus leucopus
-
New York: The National Foundation- March of Dimes, A. R. Liss, Inc
-
G.A. Sacher and R.W. Hart (1978) Longevity, aging and comparative cellular and molecular biology of the house mouse, Mus musculus, and the white-footed mouse, Peromyscus leucopus. Genetic effects on aging, birth defects Original Article Series XIV No. 1. New York: The National Foundation- March of Dimes, A. R. Liss, Inc. 71-96
-
(1978)
Genetic effects on aging, birth defects Original Article Series XIV No. 1
, pp. 71-96
-
-
Sacher, G.A.1
Hart, R.W.2
-
128
-
-
21144434217
-
Extension of murine lifespan by overexpression of catalase targeted to mitochondria
-
S.E. Schriner, N.J. Linford, G.M. Martin, P. Treuting, C.E. Ogbura, M. Emond, et al. (2005) Extension of murine lifespan by overexpression of catalase targeted to mitochondria. Science 308 1909-1911
-
(2005)
Science
, vol.308
, pp. 1909-1911
-
-
Schriner, S.E.1
Linford, N.J.2
Martin, G.M.3
Treuting, P.4
Ogbura, C.E.5
Emond, M.6
-
129
-
-
0018757962
-
Inhibition of spontaneous breast cancer formation in female C3H (Avy/a) mice by long-term treatment with dehydroepiandros-terone
-
A.G. Schwartz (1979) Inhibition of spontaneous breast cancer formation in female C3H (Avy/a) mice by long-term treatment with dehydroepiandros-terone. Cancer Res 39 1129-1132
-
(1979)
Cancer Res
, vol.39
, pp. 1129-1132
-
-
Schwartz, A.G.1
-
130
-
-
0019770685
-
Inhibition of 7,12-dimethylbenz[a] anthracene-and urethan-induced lung tumor formation in A/J mice by long-term treatment with dehydroepiandrosterone
-
A.G. Schwartz and R.H. Tannen (1981) Inhibition of 7,12-dimethylbenz[a] anthracene-and urethan-induced lung tumor formation in A/J mice by long-term treatment with dehydroepiandrosterone. Carcinogenesis 2 1335-1337
-
(1981)
Carcinogenesis
, vol.2
, pp. 1335-1337
-
-
Schwartz, A.G.1
Tannen, R.H.2
-
131
-
-
0015466216
-
Articular aging in osteoarthrosis in dwarf mice
-
R. Silberburg (1972) Articular aging in osteoarthrosis in dwarf mice. Pathol Microbiol 38 417-430
-
(1972)
Pathol Microbiol
, vol.38
, pp. 417-430
-
-
Silberburg, R.1
-
132
-
-
84884434488
-
The pituitary in relation to skeletal aging and disease
-
A.V Everitt, J.A. Burgess (Eds), Springfield, IL: Charles C. Thomas
-
R. Silberburg (1976) The pituitary in relation to skeletal aging and disease. A.V Everitt, J.A. Burgess (Eds) Hypothalamus pituitary and aging Springfield, IL: Charles C. Thomas 209-238
-
(1976)
Hypothalamus pituitary and aging
, pp. 209-238
-
-
Silberburg, R.1
-
133
-
-
19044387714
-
c-Kit expression and stem cell factor-induced hematopoietic cell proliferation are up-regu-lated in aged B6D2F1 mice. J
-
A.L. Smith, F.M Ellison, J.P. McCoy Jr. and J. Chen (2005) c-Kit expression and stem cell factor-induced hematopoietic cell proliferation are up-regu-lated in aged B6D2F1 mice. J. Gerontol B 60 448-456
-
(2005)
Gerontol B
, vol.60
, pp. 448-456
-
-
Smith, A.L.1
Ellison, F.M.2
McCoy, J.P.3
Chen, J.4
-
134
-
-
0036628724
-
Role of oxidative stress and protein oxidation in the aging process
-
R.S. Sohal (2002) Role of oxidative stress and protein oxidation in the aging process. Free Radie Biol Med 33 37-44
-
(2002)
Free Radie Biol Med
, vol.33
, pp. 37-44
-
-
Sohal, R.S.1
-
135
-
-
0021416752
-
Animals in aging research: requirements, pitfalls and a challenge for the laboratory animal specialist
-
H.A. Solleveld and C.F. Hollander (1984) Animals in aging research: requirements, pitfalls and a challenge for the laboratory animal specialist. Vet Q 6 96-101
-
(1984)
Vet Q
, vol.6
, pp. 96-101
-
-
Solleveld, H.A.1
Hollander, C.F.2
-
136
-
-
22144444220
-
Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span
-
W.E. Sonntag, C.S. Carter, Y Ikeno, K. Ekenstedt, C.S. Carlson, R.F. Loeser, et al. (2005) Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span. Endocrinology 146 2920-2932
-
(2005)
Endocrinology
, vol.146
, pp. 2920-2932
-
-
Sonntag, W.E.1
Carter, C.S.2
Ikeno, Y.3
Ekenstedt, K.4
Carlson, C.S.5
Loeser, R.F.6
-
137
-
-
0022377731
-
The involution of the ageing human thymic epithelium is independent of puberty: a morpho-metric study
-
G.G. Steinmann, B. Klaus and H.K. Muller-Hermelink (1985) The involution of the ageing human thymic epithelium is independent of puberty: a morpho-metric study. Scand J Immunol 22 563-575
-
(1985)
Scand J Immunol
, vol.22
, pp. 563-575
-
-
Steinmann, G.G.1
Klaus, B.2
Muller-Hermelink, H.K.3
-
139
-
-
0030896787
-
Senescence-accelerated mouse: a novel murine model of senescence
-
T. Takeda, M. Hosokawa and K. Higuchi (1997) Senescence-accelerated mouse: a novel murine model of senescence. Exp Gerontol 32 105-109
-
(1997)
Exp Gerontol
, vol.32
, pp. 105-109
-
-
Takeda, T.1
Hosokawa, M.2
Higuchi, K.3
-
140
-
-
0041666387
-
The role of stem cells in aging
-
G. Van Zant and Y Liang (2003) The role of stem cells in aging. Exp Hematol 31 659-672
-
(2003)
Exp Hematol
, vol.31
, pp. 659-672
-
-
Van Zant, G.1
Liang, Y.2
-
141
-
-
13444249466
-
Hormone-treated Snell dwarf mice regain fertility but remain long lived and disease resistant. J
-
M. Vergara, M. Smith-Wheelock, J.M. Harper, R. Sigler and R.A. Miller (2004) Hormone-treated Snell dwarf mice regain fertility but remain long lived and disease resistant. J. Gerontol 59 1244-1250
-
(2004)
Gerontol
, vol.59
, pp. 1244-1250
-
-
Vergara, M.1
Smith-Wheelock, M.2
Harper, J.M.3
Sigler, R.4
Miller, R.A.5
-
142
-
-
0037028155
-
The mosaic structure of variation in the laboratory mouse genome
-
C.M. Wade, E.J. Kulbokas E.J.3rd, A.W. Kirby, M.C. Zody, J.C. Mullikin, et al. (2002) The mosaic structure of variation in the laboratory mouse genome. Nature 420 574-578
-
(2002)
Nature
, vol.420
, pp. 574-578
-
-
Wade, C.M.1
Kulbokas, E.J.2
Kirby, A.W.3
Zody, M.C.4
Mullikin, J.C.5
-
143
-
-
11844280278
-
Genetics of variation in HDL cholesterol in humans and mice
-
X. Wang and B. Paigen (2005) Genetics of variation in HDL cholesterol in humans and mice. Cire Res 96 27-42
-
(2005)
Cire Res
, vol.96
, pp. 27-42
-
-
Wang, X.1
Paigen, B.2
-
144
-
-
17144398839
-
Genome-wide search for new genes controlling plasma lipid concentrations in mice and humans
-
X. Wang and B. Paigen (2005) Genome-wide search for new genes controlling plasma lipid concentrations in mice and humans. Curr Opin Lipidol 16 127-137
-
(2005)
Curr Opin Lipidol
, vol.16
, pp. 127-137
-
-
Wang, X.1
Paigen, B.2
-
145
-
-
4644219642
-
Haplotype analysis in multiple crosses to identify a QTL gene
-
X. Wang, R. Korstanje, D. Higgins and B. Paigen (2004) Haplotype analysis in multiple crosses to identify a QTL gene. Genome Res 14 1767-1772
-
(2004)
Genome Res
, vol.14
, pp. 1767-1772
-
-
Wang, X.1
Korstanje, R.2
Higgins, D.3
Paigen, B.4
-
146
-
-
0037726549
-
Models of accelerated ageing can be informa-tive about the molecular mechanisms of ageing and/or age-related pathology
-
H.R. Warner and F. Sierra (2003) Models of accelerated ageing can be informa-tive about the molecular mechanisms of ageing and/or age-related pathology. Mech Ageing Dev 124 581-587
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 581-587
-
-
Warner, H.R.1
Sierra, F.2
-
147
-
-
0343962628
-
Meeting report: program for testing biological interventions to promote healthy aging
-
H.R. Warner, D. Ingram, R.A. Miller, N.L. Nadon and A.G. Richardson (2000) Meeting report: program for testing biological interventions to promote healthy aging. Mech Ageing Dev 115 199-208
-
(2000)
Mech Ageing Dev
, vol.115
, pp. 199-208
-
-
Warner, H.R.1
Ingram, D.2
Miller, R.A.3
Nadon, N.L.4
Richardson, A.G.5
-
148
-
-
3342945004
-
Murine chromosomal regions influencing life span
-
D.E. Harrison (Eds), Caldwell, NJ: The Telford Press, Inc
-
A.L.M. Watson, R.S. German, R.M. Williams and E.J. Yunis (1990) Murine chromosomal regions influencing life span. D.E. Harrison (Eds) Genetic effects on aging II Caldwell, NJ: The Telford Press, Inc. 473-488
-
(1990)
Genetic effects on aging II
, pp. 473-488
-
-
Watson, A.L.M.1
German, R.S.2
Williams, R.M.3
Yunis, E.J.4
-
149
-
-
0010454467
-
Animal models
-
E.J. Masoro (Eds), New York: Oxford University Press, Section 11, Aging
-
R. Weindruch (1995) Animal models. E.J. Masoro (Eds) Handbook of physiology New York: Oxford University Press 37-52. Section 11, Aging
-
(1995)
Handbook of physiology
, pp. 37-52
-
-
Weindruch, R.1
-
150
-
-
0025775451
-
Concerns about rodent models for aging research. J
-
R. Weindruch and E.J. Masoro (1991) Concerns about rodent models for aging research. J. Gerontol Biol Sci 46 B87-B88
-
(1991)
Gerontol Biol Sci
, vol.46
, pp. B87-B88
-
-
Weindruch, R.1
Masoro, E.J.2
-
151
-
-
0022517746
-
The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake
-
R. Weindruch, R.L. Walford, S. Fligiel and D. Guthrie (1986) The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake. J Nutr 116 641-654
-
(1986)
J Nutr
, vol.116
, pp. 641-654
-
-
Weindruch, R.1
Walford, R.L.2
Fligiel, S.3
Guthrie, D.4
-
152
-
-
0000055057
-
Pleiotropy, natural selection and the evolution of senes-cence
-
G.C. Williams (1957) Pleiotropy, natural selection and the evolution of senes-cence. Evolution 11 398-411
-
(1957)
Evolution
, vol.11
, pp. 398-411
-
-
Williams, G.C.1
-
153
-
-
6344280944
-
Pathological changes in the liver of a senescence accelerated mouse strain (SAMP8) : a mouse model for the study of liver disease
-
X. Ye, H.C. Meeker, P.B. Kozlowski, J. Weigel, K.C. Wang, H. Imaki and R.I. Carp (2004) Pathological changes in the liver of a senescence accelerated mouse strain (SAMP8) : a mouse model for the study of liver disease. Histol Histopathol 4 1141-1151
-
(2004)
Histol Histopathol
, vol.4
, pp. 1141-1151
-
-
Ye, X.1
Meeker, H.C.2
Kozlowski, P.B.3
Weigel, J.4
Wang, K.C.5
Imaki, H.6
Carp, R.I.7
-
154
-
-
0000498145
-
Putative interventions
-
E.J. Masoro (Eds), New York: Oxford University Press, Section 11, Aging
-
B.P. Yu (1995) Putative interventions. E.J. Masoro (Eds) Handbook of physiology New York: Oxford University Press 613-632. Section 11, Aging
-
(1995)
Handbook of physiology
, pp. 613-632
-
-
Yu, B.P.1
-
155
-
-
12844250051
-
Genetic regulation of hematopoietic stem cell exhaustion during development and growth
-
R. Yuan, C.M. Astle, J. Chen and D.E. Harrison (2005) Genetic regulation of hematopoietic stem cell exhaustion during development and growth. Exp Hematol 33 243-250
-
(2005)
Exp Hematol
, vol.33
, pp. 243-250
-
-
Yuan, R.1
Astle, C.M.2
Chen, J.3
Harrison, D.E.4
-
156
-
-
0030003016
-
Distinct developmental patterns of short-term and long-term functioning lymphoid and myeloid pre-cursors defined by competitive limiting dilution analysis in vivo
-
R.K. Zhong, C.M. Astle and D.E. Harrison (1996) Distinct developmental patterns of short-term and long-term functioning lymphoid and myeloid pre-cursors defined by competitive limiting dilution analysis in vivo. J Immunol 157 138-145
-
(1996)
J Immunol
, vol.157
, pp. 138-145
-
-
Zhong, R.K.1
Astle, C.M.2
Harrison, D.E.3
|