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Volumn 21, Issue 23, 2010, Pages 4184-4196

Nuclear organization and dynamics of 7SK RNA in regulating gene expression

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BCDIN3 PROTEIN; CYCLIN DEPENDENT KINASE 9; CYCLIN T1; HEXIM 1 PROTEIN; HEXIM 2 PROTEIN; LARP7 PROTEIN; MESSENGER RNA PRECURSOR; NUCLEAR PROTEIN; RNA POLYMERASE II; SMALL NUCLEAR RNA; UNCLASSIFIED DRUG;

EID: 78650084265     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E10-02-0105     Document Type: Article
Times cited : (54)

References (92)
  • 1
  • 2
    • 29244474416 scopus 로고    scopus 로고
    • Interplay between 7SK snRNA and oppositely charged regions in HEXIM1 direct the inhibition of P-TEFb
    • Barboric, M., Kohoutek, J., Price, J. P., Blazek, D., Price, D. H., and Peterlin, B. M. (2005). Interplay between 7SK snRNA and oppositely charged regions in HEXIM1 direct the inhibition of P-TEFb. EMBO J. 24, 4291-4303.
    • (2005) EMBO J. , vol.24 , pp. 4291-4303
    • Barboric, M.1    Kohoutek, J.2    Price, J.P.3    Blazek, D.4    Price, D.H.5    Peterlin, B.M.6
  • 3
    • 66049098191 scopus 로고    scopus 로고
    • 7SK snRNP/P-TEFb couples transcription elongation with alternative splicing and is essential for vertebrate development
    • Barboric, M., Lenasi, T., Chen, H., Johansen, E. B., Guo, S., and Peterlin, B. M. (2009). 7SK snRNP/P-TEFb couples transcription elongation with alternative splicing and is essential for vertebrate development. Proc. Natl. Acad. Sci. USA 106, 7798-7803.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 7798-7803
    • Barboric, M.1    Lenasi, T.2    Chen, H.3    Johansen, E.B.4    Guo, S.5    Peterlin, B.M.6
  • 4
    • 35148867404 scopus 로고    scopus 로고
    • The transcription-dependent dissociation of P-TEFb-HEXIM1-7SK RNA relies upon formation of hnRNP-7SK RNA complexes
    • Barrandon, C., Bonnet, F., Nguyen, V. T., Labas, V., and Bensaude, O. (2007). The transcription-dependent dissociation of P-TEFb-HEXIM1-7SK RNA relies upon formation of hnRNP-7SK RNA complexes. Mol. Cell Biol. 27, 6996-7006.
    • (2007) Mol. Cell Biol. , vol.27 , pp. 6996-7006
    • Barrandon, C.1    Bonnet, F.2    Nguyen, V.T.3    Labas, V.4    Bensaude, O.5
  • 5
    • 38949188739 scopus 로고    scopus 로고
    • Non-coding RNAs regulating the transcriptional machinery
    • Barrandon, C., Spiluttini, B., and Bensaude, O. (2008). Non-coding RNAs regulating the transcriptional machinery. Biol. Cell 100, 83-95.
    • (2008) Biol. Cell , vol.100 , pp. 83-95
    • Barrandon, C.1    Spiluttini, B.2    Bensaude, O.3
  • 6
    • 29244459405 scopus 로고    scopus 로고
    • Oligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFb
    • Blazek, D., Barboric, M., Kohoutek, J., Oven, I., and Peterlin, B. M. (2005). Oligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFb. Nucleic Acids Res. 33, 7000-7010.
    • (2005) Nucleic Acids Res. , vol.33 , pp. 7000-7010
    • Blazek, D.1    Barboric, M.2    Kohoutek, J.3    Oven, I.4    Peterlin, B.M.5
  • 7
    • 0037133254 scopus 로고    scopus 로고
    • Transcription: Surprising role for an elusive small nuclear RNA
    • Blencowe, B. J. (2002). Transcription: surprising role for an elusive small nuclear RNA. Curr. Biol. 12, R147-R149.
    • (2002) Curr. Biol. , vol.12
    • Blencowe, B.J.1
  • 8
    • 0028900584 scopus 로고
    • Transcription-dependent redistribution of the large subunit of RNA polymerase II to discrete nuclear domains
    • Bregman, D. B., Du, L., van der Zee, S., and Warren, S. L. (1995). Transcription-dependent redistribution of the large subunit of RNA polymerase II to discrete nuclear domains. J. Cell Biol. 129, 287-298.
    • (1995) J. Cell Biol. , vol.129 , pp. 287-298
    • Bregman, D.B.1    Du, L.2    Van Der Zee, S.3    Warren, S.L.4
  • 9
    • 5444269465 scopus 로고    scopus 로고
    • Hypophosphorylated SR splicing factors transiently localize around active nucleolar organizing regions in telophase daughter nuclei
    • Bubulya, P. A., Prasanth, K. V., Deerinck, T. J., Gerlich, D., Beaudouin, J., Ellisman, M. H., Ellenberg, J., and Spector, D. L. (2004). Hypophosphorylated SR splicing factors transiently localize around active nucleolar organizing regions in telophase daughter nuclei. J. Cell Biol. 167, 51-63.
    • (2004) J. Cell Biol. , vol.167 , pp. 51-63
    • Bubulya, P.A.1    Prasanth, K.V.2    Deerinck, T.J.3    Gerlich, D.4    Beaudouin, J.5    Ellisman, M.H.6    Ellenberg, J.7    Spector, D.L.8
  • 10
    • 18144371989 scopus 로고    scopus 로고
    • HEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SK
    • Byers, S. A., Price, J. P., Cooper, J. J., Li, Q., and Price, D. H. (2005). HEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SK. J. Biol. Chem. 280, 16360-16367.
    • (2005) J. Biol. Chem. , vol.280 , pp. 16360-16367
    • Byers, S.A.1    Price, J.P.2    Cooper, J.J.3    Li, Q.4    Price, D.H.5
  • 11
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin, G. A., and Croce, C. M. (2006). MicroRNA signatures in human cancers. Nat. Rev. Cancer 6, 857-866.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 12
    • 0025786160 scopus 로고
    • Discrete nuclear domains of poly(A) RNA and their relationship to the functional organization of the nucleus
    • Carter, K. C., Taneja, K. L., and Lawrence, J. B. (1991). Discrete nuclear domains of poly(A) RNA and their relationship to the functional organization of the nucleus. J. Cell Biol. 115, 1191-1202.
    • (1991) J. Cell Biol. , vol.115 , pp. 1191-1202
    • Carter, K.C.1    Taneja, K.L.2    Lawrence, J.B.3
  • 13
    • 68949212914 scopus 로고    scopus 로고
    • Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: Functional role of a nuclear noncoding RNA
    • Chen, L. L., and Carmichael, G. G. (2009). Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNA. Mol. Cell 35, 467-478.
    • (2009) Mol. Cell , vol.35 , pp. 467-478
    • Chen, L.L.1    Carmichael, G.G.2
  • 14
    • 62549117314 scopus 로고    scopus 로고
    • An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles
    • Clemson, C. M., Hutchinson, J. N., Sara, S. A., Ensminger, A. W., Fox, A. H., Chess, A., and Lawrence, J. B. (2009). An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. Mol. Cell 33, 717-726.
    • (2009) Mol. Cell , vol.33 , pp. 717-726
    • Clemson, C.M.1    Hutchinson, J.N.2    Sara, S.A.3    Ensminger, A.W.4    Fox, A.H.5    Chess, A.6    Lawrence, J.B.7
  • 15
    • 24744440117 scopus 로고    scopus 로고
    • Non-coding RNAs: New players in eukaryotic biology
    • Costa, F. F. (2005). Non-coding RNAs: new players in eukaryotic biology. Gene 357, 83-94.
    • (2005) Gene , vol.357 , pp. 83-94
    • Costa, F.F.1
  • 16
    • 33845474731 scopus 로고    scopus 로고
    • Non-coding RNAs: Lost in translation?
    • Costa, F. F. (2007). Non-coding RNAs: lost in translation? Gene 386, 1-10.
    • (2007) Gene , vol.386 , pp. 1-10
    • Costa, F.F.1
  • 19
    • 66449089824 scopus 로고    scopus 로고
    • 7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor
    • Diribarne, G., and Bensaude, O. (2009). 7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor. RNA Biol. 6, 122-128.
    • (2009) RNA Biol. , vol.6 , pp. 122-128
    • Diribarne, G.1    Bensaude, O.2
  • 20
    • 30644478471 scopus 로고    scopus 로고
    • Regulation of polymerase II transcription by 7SK snRNA: Two distinct RNA elements direct P-TEFb and HEXIM1 binding
    • Egloff, S., Van Herreweghe, E., and Kiss, T. (2006). Regulation of polymerase II transcription by 7SK snRNA: two distinct RNA elements direct P-TEFb and HEXIM1 binding. Mol. Cell Biol. 26, 630-642.
    • (2006) Mol. Cell Biol. , vol.26 , pp. 630-642
    • Egloff, S.1    Van Herreweghe, E.2    Kiss, T.3
  • 21
    • 23644443393 scopus 로고    scopus 로고
    • The amazing complexity of the human transcriptome
    • Frith, M. C., Pheasant, M., and Mattick, J. S. (2005). The amazing complexity of the human transcriptome. Eur. J. Hum. Genet 13, 894-897.
    • (2005) Eur. J. Hum. Genet , vol.13 , pp. 894-897
    • Frith, M.C.1    Pheasant, M.2    Mattick, J.S.3
  • 22
    • 0025115231 scopus 로고
    • Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus
    • DOI 10.1038/343437a0
    • Fu, X. D., and Maniatis, T. (1990). Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus. Nature 343, 437-441. (Pubitemid 20065230)
    • (1990) Nature , vol.343 , Issue.6257 , pp. 437-441
    • Fu, X.-D.1    Maniatis, T.2
  • 23
    • 0019135807 scopus 로고
    • Intracellular distribution of low molecular weight RNA species in HeLa cells
    • Gurney, T., Jr., and Eliceiri, G. L. (1980). Intracellular distribution of low molecular weight RNA species in HeLa cells. J. Cell Biol. 87, 398-403.
    • (1980) J. Cell Biol. , vol.87 , pp. 398-403
    • Gurney Jr., T.1    Eliceiri, G.L.2
  • 24
    • 27744459377 scopus 로고    scopus 로고
    • SiRNA depletion of 7SK snRNA induces apoptosis but does not affect expression of the HIV-1 LTR or P-TEFb-dependent cellular genes
    • Haaland, R. E., Herrmann, C. H., and Rice, A. P. (2005). siRNA depletion of 7SK snRNA induces apoptosis but does not affect expression of the HIV-1 LTR or P-TEFb-dependent cellular genes. J. Cell Physiol. 205, 463-470.
    • (2005) J. Cell Physiol. , vol.205 , pp. 463-470
    • Haaland, R.E.1    Herrmann, C.H.2    Rice, A.P.3
  • 25
    • 0022081733 scopus 로고
    • Autoantibodies to ribonucleoprotein particles containing U2 small nuclear RNA
    • Habets, W., Hoet, M., Bringmann, P., Luhrmann, R., and van Venrooij, W. (1985). Autoantibodies to ribonucleoprotein particles containing U2 small nuclear RNA. EMBO J. 4, 1545-1550.
    • (1985) EMBO J. , vol.4 , pp. 1545-1550
    • Habets, W.1    Hoet, M.2    Bringmann, P.3    Luhrmann, R.4    Van Venrooij, W.5
  • 27
    • 40649100262 scopus 로고    scopus 로고
    • A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis
    • He, N., Jahchan, N. S., Hong, E., Li, Q., Bayfield, M. A., Maraia, R. J., Luo, K., and Zhou, Q. (2008). A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis. Mol. Cell 29, 588-599.
    • (2008) Mol. Cell , vol.29 , pp. 588-599
    • He, N.1    Jahchan, N.S.2    Hong, E.3    Li, Q.4    Bayfield, M.A.5    Maraia, R.J.6    Luo, K.7    Zhou, Q.8
  • 28
    • 0035022568 scopus 로고    scopus 로고
    • The Cdk9 and cyclin T subunits of TAK/P-TEFb localize to splicing factor-rich nuclear speckle regions
    • Herrmann, C. H., and Mancini, M. A. (2001). The Cdk9 and cyclin T subunits of TAK/P-TEFb localize to splicing factor-rich nuclear speckle regions. J. Cell Sci. 114, 1491-1503.
    • (2001) J. Cell Sci. , vol.114 , pp. 1491-1503
    • Herrmann, C.H.1    Mancini, M.A.2
  • 29
    • 34249053165 scopus 로고    scopus 로고
    • RNA-based affinity purification reveals 7SK RNPs with distinct composition and regulation
    • Hogg, J. R., and Collins, K. (2007). RNA-based affinity purification reveals 7SK RNPs with distinct composition and regulation. RNA 13, 868-880.
    • (2007) RNA , vol.13 , pp. 868-880
    • Hogg, J.R.1    Collins, K.2
  • 30
    • 0027930199 scopus 로고
    • In vivo analysis of the stability and transport of nuclear poly(A)+ RNA
    • Huang, S., Deerinck, T. J., Ellisman, M. H., and Spector, D. L. (1994). In vivo analysis of the stability and transport of nuclear poly(A)+ RNA. J. Cell Biol. 126, 877-899.
    • (1994) J. Cell Biol. , vol.126 , pp. 877-899
    • Huang, S.1    Deerinck, T.J.2    Ellisman, M.H.3    Spector, D.L.4
  • 31
    • 33847185603 scopus 로고    scopus 로고
    • A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains
    • Hutchinson, J. N., Ensminger, A. W., Clemson, C. M., Lynch, C. R., Lawrence, J. B., and Chess, A. (2007). A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains. BMC Genomics 8, 39.
    • (2007) BMC Genomics , vol.8 , pp. 39
    • Hutchinson, J.N.1    Ensminger, A.W.2    Clemson, C.M.3    Lynch, C.R.4    Lawrence, J.B.5    Chess, A.6
  • 33
    • 0344429906 scopus 로고    scopus 로고
    • MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer
    • Ji, P., et al. (2003). MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene 22, 8031-8041.
    • (2003) Oncogene , vol.22 , pp. 8031-8041
    • Ji, P.1
  • 34
    • 34249088350 scopus 로고    scopus 로고
    • Genome-wide transcription and the implications for genomic organization
    • Kapranov, P., Willingham, A. T., and Gingeras, T. R. (2007). Genome-wide transcription and the implications for genomic organization. Nat. Rev. Genet 8, 413-423.
    • (2007) Nat. Rev. Genet , vol.8 , pp. 413-423
    • Kapranov, P.1    Willingham, A.T.2    Gingeras, T.R.3
  • 35
    • 42449086866 scopus 로고    scopus 로고
    • LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated
    • Krueger, B. J., et al. (2008). LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated. Nucleic Acids Res. 36, 2219-2229.
    • (2008) Nucleic Acids Res. , vol.36 , pp. 2219-2229
    • Krueger, B.J.1
  • 36
    • 0023191134 scopus 로고
    • Structural and functional analysis of a human 7 S K RNA gene
    • Kruger, W., and Benecke, B. J. (1987). Structural and functional analysis of a human 7 S K RNA gene. J. Mol. Biol. 195, 31-41.
    • (1987) J. Mol. Biol. , vol.195 , pp. 31-41
    • Kruger, W.1    Benecke, B.J.2
  • 37
    • 0041669439 scopus 로고    scopus 로고
    • Nuclear speckles: A model for nuclear organelles
    • Lamond, A. I., and Spector, D. L. (2003). Nuclear speckles: a model for nuclear organelles. Nat. Rev. Mol. Cell Biol. 4, 605-612.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 605-612
    • Lamond, A.I.1    Spector, D.L.2
  • 38
    • 33846133499 scopus 로고    scopus 로고
    • A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas
    • Lin, R., Maeda, S., Liu, C., Karin, M., and Edgington, T. S. (2006). A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas. Oncogene.
    • (2006) Oncogene
    • Lin, R.1    Maeda, S.2    Liu, C.3    Karin, M.4    Edgington, T.S.5
  • 40
    • 42449159377 scopus 로고    scopus 로고
    • SR proteins and related factors in alternative splicing
    • Lin, S., and Fu, X. D. (2007). SR proteins and related factors in alternative splicing. Adv. Exper. Med. Biol. 623, 107-122.
    • (2007) Adv. Exper. Med. Biol. , vol.623 , pp. 107-122
    • Lin, S.1    Fu, X.D.2
  • 41
    • 58249093940 scopus 로고    scopus 로고
    • The SR protein family of splicing factors: Master regulators of gene expression
    • Long, J. C., and Caceres, J. F. (2009). The SR protein family of splicing factors: master regulators of gene expression. Biochem. J. 417, 15-27.
    • (2009) Biochem. J. , vol.417 , pp. 15-27
    • Long, J.C.1    Caceres, J.F.2
  • 42
    • 44649135099 scopus 로고    scopus 로고
    • The La-related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genes
    • DOI 10.1038/embor.2008.72, PII EMBOR200872
    • Markert, A., Grimm, M., Martinez, J., Wiesner, J., Meyerhans, A., Meyuhas, O., Sickmann, A., and Fischer, U. (2008). The La-related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genes. EMBO Rep. 9, 569-575. (Pubitemid 351772921)
    • (2008) EMBO Reports , vol.9 , Issue.6 , pp. 569-575
    • Markert, A.1    Grimm, M.2    Martinez, J.3    Wiesner, J.4    Meyerhans, A.5    Meyuhas, O.6    Sickmann, A.7    Fischer, U.8
  • 43
    • 71849090342 scopus 로고    scopus 로고
    • Nuclear bodies: Random aggregates of sticky proteins or crucibles of macromolecular assembly?
    • Matera, A. G., Izaguire-Sierra, M., Praveen, K., and Rajendra, T. K. (2009). Nuclear bodies: random aggregates of sticky proteins or crucibles of macromolecular assembly? Dev. Cell 17, 639-647.
    • (2009) Dev. Cell , vol.17 , pp. 639-647
    • Matera, A.G.1    Izaguire-Sierra, M.2    Praveen, K.3    Rajendra, T.K.4
  • 44
    • 0027294645 scopus 로고
    • Nucleoplasmic organization of small nuclear ribonucleoproteins in cultured human cells
    • Matera, A. G., and Ward, D. C. (1993). Nucleoplasmic organization of small nuclear ribonucleoproteins in cultured human cells. J. Cell Biol. 121, 715-727.
    • (1993) J. Cell Biol. , vol.121 , pp. 715-727
    • Matera, A.G.1    Ward, D.C.2
  • 45
    • 0035195942 scopus 로고    scopus 로고
    • Non-coding RNAs: The architects of eukaryotic complexity
    • Mattick, J. S. (2001). Non-coding RNAs: the architects of eukaryotic complexity. EMBO Rep. 2, 986-991.
    • (2001) EMBO Rep. , vol.2 , pp. 986-991
    • Mattick, J.S.1
  • 46
    • 1842584883 scopus 로고    scopus 로고
    • RNA regulation: A new genetics?
    • Mattick, J. S. (2004a). RNA regulation: a new genetics? Nat. Rev. Genet 5, 316-323.
    • (2004) Nat. Rev. Genet , vol.5 , pp. 316-323
    • Mattick, J.S.1
  • 47
    • 24644443227 scopus 로고    scopus 로고
    • The functional genomics of noncoding RNA
    • Mattick, J. S. (2005). The functional genomics of noncoding RNA. Science 309, 1527-1528.
    • (2005) Science , vol.309 , pp. 1527-1528
    • Mattick, J.S.1
  • 48
    • 65649092633 scopus 로고    scopus 로고
    • The genetic signatures of noncoding RNAs
    • Mattick, J. S. (2009). The genetic signatures of noncoding RNAs. PLoS Genet 5, e1000459.
    • (2009) PLoS Genet , vol.5
    • Mattick, J.S.1
  • 50
    • 60349120914 scopus 로고    scopus 로고
    • Long non-coding RNAs: Insights into functions
    • Mercer, T. R., Dinger, M. E., and Mattick, J. S. (2009). Long non-coding RNAs: insights into functions. Nat. Rev. Genet 10, 155-159.
    • (2009) Nat. Rev. Genet , vol.10 , pp. 155-159
    • Mercer, T.R.1    Dinger, M.E.2    Mattick, J.S.3
  • 52
    • 51649089956 scopus 로고    scopus 로고
    • RNA-driven cyclin-dependent kinase regulation: When CDK9/cyclin T subunits of P-TEFb meet their ribonucleoprotein partners
    • Michels, A. A., and Bensaude, O. (2008). RNA-driven cyclin-dependent kinase regulation: when CDK9/cyclin T subunits of P-TEFb meet their ribonucleoprotein partners. Biotech. J. 3, 1022-1032.
    • (2008) Biotech. J. , vol.3 , pp. 1022-1032
    • Michels, A.A.1    Bensaude, O.2
  • 55
    • 0035793376 scopus 로고    scopus 로고
    • Protein dynamics: Implications for nuclear architecture and gene expression
    • Misteli, T. (2001). Protein dynamics: implications for nuclear architecture and gene expression. Science 291, 843-847.
    • (2001) Science , vol.291 , pp. 843-847
    • Misteli, T.1
  • 56
    • 37449019712 scopus 로고    scopus 로고
    • Physiological importance of RNA and protein mobility in the cell nucleus
    • Misteli, T. (2008). Physiological importance of RNA and protein mobility in the cell nucleus. Histochem. and cell biology 129, 5-11.
    • (2008) Histochem. and Cell Biology , vol.129 , pp. 5-11
    • Misteli, T.1
  • 57
    • 0031128181 scopus 로고    scopus 로고
    • Protein phosphorylation and the nuclear organization of pre-mRNA splicing
    • Misteli, T., and Spector, D. L. (1997). Protein phosphorylation and the nuclear organization of pre-mRNA splicing. Trends Cell Biol. 7, 135-138.
    • (1997) Trends Cell Biol. , vol.7 , pp. 135-138
    • Misteli, T.1    Spector, D.L.2
  • 58
    • 0036170782 scopus 로고    scopus 로고
    • Metabolic-energy-dependent movement of PML bodies within the mammalian cell nucleus
    • Muratani, M., Gerlich, D., Janicki, S. M., Gebhard, M., Eils, R., and Spector, D. L. (2002). Metabolic-energy-dependent movement of PML bodies within the mammalian cell nucleus. Nat. Cell Biol. 4, 106-110.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 106-110
    • Muratani, M.1    Gerlich, D.2    Janicki, S.M.3    Gebhard, M.4    Eils, R.5    Spector, D.L.6
  • 59
    • 0023649209 scopus 로고
    • The in vitro transcription of the 7SK RNA gene by RNA polymerase III is dependent only on the presence of an upstream promoter
    • Murphy, S., Di Liegro, C., and Melli, M. (1987). The in vitro transcription of the 7SK RNA gene by RNA polymerase III is dependent only on the presence of an upstream promoter. Cell 51, 81-87.
    • (1987) Cell , vol.51 , pp. 81-87
    • Murphy, S.1    Di Liegro, C.2    Melli, M.3
  • 60
    • 0035891288 scopus 로고    scopus 로고
    • 7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
    • Nguyen, V. T., Kiss, T., Michels, A. A., and Bensaude, O. (2001). 7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes. Nature 414, 322-325.
    • (2001) Nature , vol.414 , pp. 322-325
    • Nguyen, V.T.1    Kiss, T.2    Michels, A.A.3    Bensaude, O.4
  • 61
    • 0027953244 scopus 로고
    • Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors
    • O'Keefe, R. T., Mayeda, A., Sadowski, C. L., Krainer, A. R., and Spector, D. L. (1994). Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors. J. Cell Biol. 124, 249-260.
    • (1994) J. Cell Biol. , vol.124 , pp. 249-260
    • O'Keefe, R.T.1    Mayeda, A.2    Sadowski, C.L.3    Krainer, A.R.4    Spector, D.L.5
  • 64
    • 0036196574 scopus 로고    scopus 로고
    • FBI-1 can stimulate HIV-1 Tat activity and is targeted to a novel subnuclear domain that includes the Tat-P-TEFb-containing nuclear speckles
    • Pendergrast, P. S., Wang, C., Hernandez, N., and Huang, S. (2002). FBI-1 can stimulate HIV-1 Tat activity and is targeted to a novel subnuclear domain that includes the Tat-P-TEFb-containing nuclear speckles. Mol. Biol. Cell 13, 915-929.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 915-929
    • Pendergrast, P.S.1    Wang, C.2    Hernandez, N.3    Huang, S.4
  • 65
    • 33746403681 scopus 로고    scopus 로고
    • Controlling the elongation phase of transcription with P-TEFb
    • Peterlin, B. M., and Price, D. H. (2006). Controlling the elongation phase of transcription with P-TEFb. Mol. Cell 23, 297-305.
    • (2006) Mol. Cell , vol.23 , pp. 297-305
    • Peterlin, B.M.1    Price, D.H.2
  • 66
    • 34548432104 scopus 로고    scopus 로고
    • Raising the estimate of functional human sequences
    • DOI 10.1101/gr.6406307
    • Pheasant, M., and Mattick, J. S. (2007). Raising the estimate of functional human sequences. Genome Res. 17, 1245-1253. (Pubitemid 47360899)
    • (2007) Genome Research , vol.17 , Issue.9 , pp. 1245-1253
    • Pheasant, M.1    Mattick, J.S.2
  • 67
    • 0036302047 scopus 로고    scopus 로고
    • Cajal body dynamics and association with chromatin are ATP-dependent
    • Platani, M., Goldberg, I., Lamond, A. I., and Swedlow, J. R. (2002). Cajal body dynamics and association with chromatin are ATP-dependent. Nat. Cell Biol. 4, 502-508.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 502-508
    • Platani, M.1    Goldberg, I.2    Lamond, A.I.3    Swedlow, J.R.4
  • 69
    • 0037339967 scopus 로고    scopus 로고
    • Sequential entry of components of the gene expression machinery into daughter nuclei
    • Prasanth, K. V., Sacco-Bubulya, P. A., Prasanth, S. G., and Spector, D. L. (2003). Sequential entry of components of the gene expression machinery into daughter nuclei. Mol. Biol. Cell 14, 1043-1057.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 1043-1057
    • Prasanth, K.V.1    Sacco-Bubulya, P.A.2    Prasanth, S.G.3    Spector, D.L.4
  • 70
    • 84855631177 scopus 로고    scopus 로고
    • The cell nucleus
    • John Wiley & Sons, Ltd: Chichester doi: 10.1038/npg.els. 0001337
    • Prasanth, K. V., and Spector, D. L. (2005). The cell nucleus. In: Encyclopedia of Life Sciences. John Wiley & Sons, Ltd: Chichester http://www.els.net/ [doi: 10.1038/npg.els. 0001337].
    • (2005) Encyclopedia of Life Sciences
    • Prasanth, K.V.1    Spector, D.L.2
  • 71
    • 33846169089 scopus 로고    scopus 로고
    • Eukaryotic regulatory RNAs: An answer to the 'genome complexity' conundrum
    • Prasanth, K. V., and Spector, D. L. (2007). Eukaryotic regulatory RNAs: an answer to the 'genome complexity' conundrum. Genes Dev. 21, 11-42.
    • (2007) Genes Dev. , vol.21 , pp. 11-42
    • Prasanth, K.V.1    Spector, D.L.2
  • 72
    • 0037017406 scopus 로고    scopus 로고
    • Disassembly of interchromatin granule clusters alters the coordination of transcription and pre-mRNA splicing
    • Sacco-Bubulya, P., and Spector, D. L. (2002). Disassembly of interchromatin granule clusters alters the coordination of transcription and pre-mRNA splicing. J. Cell Biol. 156, 425-436.
    • (2002) J. Cell Biol. , vol.156 , pp. 425-436
    • Sacco-Bubulya, P.1    Spector, D.L.2
  • 73
    • 0036851825 scopus 로고    scopus 로고
    • Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac musclecell hypertrophy
    • Sano, M., Abdellatif, M., Oh, H., Xie, M., Bagella, L., Giordano, A., Michael, L. H., DeMayo, F. J., and Schneider, M. D. (2002). Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac musclecell hypertrophy. Nat. Med. 8, 1310-1317.
    • (2002) Nat. Med. , vol.8 , pp. 1310-1317
    • Sano, M.1    Abdellatif, M.2    Oh, H.3    Xie, M.4    Bagella, L.5    Giordano, A.6    Michael, L.H.7    DeMayo, F.J.8    Schneider, M.D.9
  • 74
    • 62449319486 scopus 로고    scopus 로고
    • ME-Nepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles
    • Sasaki, Y. T., Ideue, T., Sano, M., Mituyama, T., and Hirose, T. (2009). ME-Nepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles. Proc. Natl. Acad. Sci. USA 106, 2525-2530.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 2525-2530
    • Sasaki, Y.T.1    Ideue, T.2    Sano, M.3    Mituyama, T.4    Hirose, T.5
  • 76
    • 33751203862 scopus 로고    scopus 로고
    • SnapShot: Cellular bodies
    • Spector, D. L. (2006). SnapShot: cellular bodies. Cell 127, 1071.
    • (2006) Cell , vol.127 , pp. 1071
    • Spector, D.L.1
  • 77
    • 0021082681 scopus 로고
    • Immunoelectron microscopic localization of snRNPs
    • Spector, D. L., Schrier, W. H., and Busch, H. (1983). Immunoelectron microscopic localization of snRNPs. Biol. Cell 49, 1-10.
    • (1983) Biol. Cell , vol.49 , pp. 1-10
    • Spector, D.L.1    Schrier, W.H.2    Busch, H.3
  • 78
    • 61849113891 scopus 로고    scopus 로고
    • MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles
    • Sunwoo, H., Dinger, M. E., Wilusz, J. E., Amaral, P. P., Mattick, J. S., and Spector, D. L. (2009). MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles. Genome Res. 19, 347-359.
    • (2009) Genome Res. , vol.19 , pp. 347-359
    • Sunwoo, H.1    Dinger, M.E.2    Wilusz, J.E.3    Amaral, P.P.4    Mattick, J.S.5    Spector, D.L.6
  • 82
    • 0025831431 scopus 로고
    • Structural analyses of the 7SK ribonucleoprotein (RNP), the most abundant human small RNP of unknown function
    • Wassarman, D. A., and Steitz, J. A. (1991). Structural analyses of the 7SK ribonucleoprotein (RNP), the most abundant human small RNP of unknown function. Mol. Cell Biol. 11, 3432-3445.
    • (1991) Mol. Cell Biol. , vol.11 , pp. 3432-3445
    • Wassarman, D.A.1    Steitz, J.A.2
  • 83
    • 33745286231 scopus 로고    scopus 로고
    • TUF love for "junk" DNA
    • Willingham, A. T., and Gingeras, T. R. (2006). TUF love for "junk" DNA. Cell 125, 1215-1220.
    • (2006) Cell , vol.125 , pp. 1215-1220
    • Willingham, A.T.1    Gingeras, T.R.2
  • 84
    • 56349113455 scopus 로고    scopus 로고
    • 3′ end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA
    • Wilusz, J. E., Freier, S. M., and Spector, D. L. (2008). 3′ end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA. Cell 135, 919-932.
    • (2008) Cell , vol.135 , pp. 919-932
    • Wilusz, J.E.1    Freier, S.M.2    Spector, D.L.3
  • 85
    • 67649671961 scopus 로고    scopus 로고
    • Long noncoding RNAs: Functional surprises from the RNA world
    • Wilusz, J. E., Sunwoo, H., and Spector, D. L. (2009). Long noncoding RNAs: functional surprises from the RNA world. Genes Dev. 23, 1494-1504.
    • (2009) Genes Dev. , vol.23 , pp. 1494-1504
    • Wilusz, J.E.1    Sunwoo, H.2    Spector, D.L.3
  • 86
    • 0035891271 scopus 로고    scopus 로고
    • The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription
    • Yang, Z., Zhu, Q., Luo, K., and Zhou, Q. (2001). The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription. Nature 414, 317-322.
    • (2001) Nature , vol.414 , pp. 317-322
    • Yang, Z.1    Zhu, Q.2    Luo, K.3    Zhou, Q.4
  • 87
    • 0242361319 scopus 로고    scopus 로고
    • Inhibition of P-TEFb (CDK9/cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA
    • DOI 10.1016/S1097-2765(03)00388-5
    • Yik, J. H., Chen, R., Nishimura, R., Jennings, J. L., Link, A. J., and Zhou, Q. (2003). Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA. Mol. Cell 12, 971-982. (Pubitemid 37352789)
    • (2003) Molecular Cell , vol.12 , Issue.4 , pp. 971-982
    • Yik, J.H.N.1    Chen, R.2    Nishimura, R.3    Jennings, J.L.4    Link, A.J.5    Zhou, Q.6
  • 88
    • 2942628287 scopus 로고    scopus 로고
    • A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb
    • Yik, J. H., Chen, R., Pezda, A. C., Samford, C. S., and Zhou, Q. (2004). A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb. Mol. Cell Biol. 24, 5094-5105.
    • (2004) Mol. Cell Biol. , vol.24 , pp. 5094-5105
    • Yik, J.H.1    Chen, R.2    Pezda, A.C.3    Samford, C.S.4    Zhou, Q.5
  • 89
    • 18144422796 scopus 로고    scopus 로고
    • Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription
    • Yik, J. H., Chen, R., Pezda, A. C., and Zhou, Q. (2005). Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription. J. Biol. Chem. 280, 16368-16376.
    • (2005) J. Biol. Chem. , vol.280 , pp. 16368-16376
    • Yik, J.H.1    Chen, R.2    Pezda, A.C.3    Zhou, Q.4
  • 90
    • 67649671966 scopus 로고    scopus 로고
    • SR proteins in vertical integration of gene expression from transcription to RNA processing to translation
    • Zhong, X. Y., Wang, P., Han, J., Rosenfeld, M. G., and Fu, X. D. (2009). SR proteins in vertical integration of gene expression from transcription to RNA processing to translation. Mol. Cell 35, 1-10.
    • (2009) Mol. Cell , vol.35 , pp. 1-10
    • Zhong, X.Y.1    Wang, P.2    Han, J.3    Rosenfeld, M.G.4    Fu, X.D.5
  • 91
    • 33749234198 scopus 로고    scopus 로고
    • The Yin and Yang of P-TEFb regulation: Implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation
    • Zhou, Q., and Yik, J. H. (2006). The Yin and Yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation. Microbiol. Mol. Biol. Rev. 70, 646-659.
    • (2006) Microbiol. Mol. Biol. Rev. , vol.70 , pp. 646-659
    • Zhou, Q.1    Yik, J.H.2
  • 92
    • 0017160239 scopus 로고
    • Small RNA species of the HeLa cell: Metabolism and subcellular localization
    • Zieve, G., and Penman, S. (1976). Small RNA species of the HeLa cell: metabolism and subcellular localization. Cell 8, 19-31.
    • (1976) Cell , vol.8 , pp. 19-31
    • Zieve, G.1    Penman, S.2


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