An Inducer of VGF protects cells against ER stress-induced cell death and prolongs survival in the mutant SOD1 animal Models of Familial ALS

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Shimazawa, Masamitsu ^a   Tanaka, Hirotaka ^a   Ito, Yasushi ^a   Morimoto, Nobutaka ^a   Tsuruma, Kazuhiro ^a   Kadokura, Michinori ^b   Tamura, Shigeki ^b   Inoue, Teruyoshi ^b   Yamada, Mitsunori ^c   Takahashi, Hitoshi ^d   Warita, Hitoshi ^e   Aoki, Masashi ^e   Hara, Hideaki ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b DAIICHI SANKYO CO   (Japan)

^c National Saigata Medical Center   (Japan)

^d NIIGATA UNIVERSITY   (Japan)

^e TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (AMINO 2,3,5 TRIMETHYLPHENOXY) 3 [4 [4 (4 FLUOROBENZYL)PHENYL] 1 PIPERAZINYL] 2 PROPANOL DIMETHANESULFONATE; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR INDUCIBLE PROTEIN; NEUROPROTECTIVE AGENT; SMALL INTERFERING RNA; SUN N 8075; UNCLASSIFIED DRUG; ANILINE DERIVATIVE; COPPER ZINC SUPEROXIDE DISMUTASE; PIPERAZINE DERIVATIVE; SUN N8075; SUPEROXIDE DISMUTASE; VASCULOTROPIN A;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE FUNCTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; SPINAL CORD; SURVIVAL TIME; TISSUE LEVEL; ANIMAL; DISEASE MODEL; DNA MICROARRAY; ENDOPLASMIC RETICULUM; GENETICS; METABOLISM; MUTATION; TRANSGENIC MOUSE;

ANIMALIA; MUS; MUS MUSCULUS; RATTUS;

AMYOTROPHIC LATERAL SCLEROSIS; ANILINE COMPOUNDS; ANIMALS; CELL DEATH; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENDOPLASMIC RETICULUM; HUMANS; MICE; MICE, TRANSGENIC; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PIPERAZINES; SUPEROXIDE DISMUTASE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 78650080391     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015307     Document Type: Article

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