SCOPUS 정보 검색 플랫폼

Volumn 11, Issue 18, 2010, Pages 2549-2556

Structural basis for the properties of two single-site proline mutants of CYP102A1 (P450BM3)

(10) Whitehouse, Christopher J C a Yang, Wen b Yorke, Jake A a Rowlatt, Benjamin C a Strong, Anthony J F a Blanford, Christopher F a Bell, Stephen G a Bartlam, Mark b Wong, Luet Lok a Rao, Zihe b,c

a UNIVERSITY OF OXFORD (United Kingdom)

b NANKAI UNIVERSITY (China)

c TSINGHUA UNIVERSITY (China)

Author keywords

Catalysis; Cytochromes; Electron transfer; Enzyme evolution; Protein structures

Indexed keywords

CYTOCHROME P450 BM3; FLUORENE; HEME; PROLINE; PROPANE;

ARTICLE; CHEMICAL BOND; CRYSTAL STRUCTURE; HYDROGEN BOND; HYDROXYLATION; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE;

BACILLUS MEGATERIUM; BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; ELECTRON TRANSPORT; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXIDATION-REDUCTION; PROLINE; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

BACILLUS MEGATERIUM;

EID: 78650032427 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201000421 Document Type: Article

Times cited : (64)

References (54)

1
- 84892292579
- Cytochrome P450: Structure, Mechanism and Biochemistry
- 3rd ed., Plenum, New York
- P. R. Ortiz de Montellano, Cytochrome P450: Structure, Mechanism and Biochemistry 3rd ed., Plenum, New York, 2005.
- (2005)
- de Montellano, P.R.O.¹

2
- 33746021124
- S. Eiben, L. Kaysser, S. Maurer, K. Kuhnel, V. B. Urlacher, R. D. Schmid, J. Biotechnol. 2006, 124, 662.
- (2006) J. Biotechnol. , vol.124 , pp. 662
- Eiben, S.¹ Kaysser, L.² Maurer, S.³ Kuhnel, K.⁴ Urlacher, V.B.⁵ Schmid, R.D.⁶

3
- 57149139340
- S. G. Bell, N. Hoskins, C. J. C. Whitehouse, L. L. Wong, Met. Ions Life Sci. 2007, 3, 437.
- (2007) Met. Ions Life Sci. , vol.3 , pp. 437
- Bell, S.G.¹ Hoskins, N.² Whitehouse, C.J.C.³ Wong, L.L.⁴

4
- 4043107097
- V. B. Urlacher, R. D. Schmid, Methods Enzymol. 2004, 388, 208.
- (2004) Methods Enzymol. , vol.388 , pp. 208
- Urlacher, V.B.¹ Schmid, R.D.²

5
- 0034819837
- A. B. Carmichael, L. L. Wong, Eur. J. Biochem. 2001, 268, 3117.
- (2001) Eur. J. Biochem. , vol.268 , pp. 3117
- Carmichael, A.B.¹ Wong, L.L.²

6
- 53549085133
- R. Fasan, Y. T. Meharenna, C. D. Snow, T. L. Poulos, F. H. Arnold, J. Mol. Biol. 2008, 383, 1069.
- (2008) J. Mol. Biol. , vol.383 , pp. 1069
- Fasan, R.¹ Meharenna, Y.T.² Snow, C.D.³ Poulos, T.L.⁴ Arnold, F.H.⁵

7
- 70349751735
- J. C. Lewis, S. Bastian, C. S. Bennett, Y. Fu, Y. Mitsuda, M. M. Chen, W. A. Greenberg, C. H. Wong, F. H. Arnold, Proc. Natl. Acad. Sci. USA 2009, 106, 16550.
- (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 16550
- Lewis, J.C.¹ Bastian, S.² Bennett, C.S.³ Fu, Y.⁴ Mitsuda, Y.⁵ Chen, M.M.⁶ Greenberg, W.A.⁷ Wong, C.H.⁸ Arnold, F.H.⁹

8
- 11844256914
- R. J. Sowden, S. Yasmin, N. H. Rees, S. G. Bell, L. L. Wong, Org. Biomol. Chem. 2005, 3, 57.
- (2005) Org. Biomol. Chem. , vol.3 , pp. 57
- Sowden, R.J.¹ Yasmin, S.² Rees, N.H.³ Bell, S.G.⁴ Wong, L.L.⁵

9
- 65549113338
- A. Seifert, S. Vomund, K. Grohmann, S. Kriening, V. B. Urlacher, S. Laschat, J. Pleiss, ChemBioChem 2009, 10, 853.
- (2009) ChemBioChem , vol.10 , pp. 853
- Seifert, A.¹ Vomund, S.² Grohmann, K.³ Kriening, S.⁴ Urlacher, V.B.⁵ Laschat, S.⁶ Pleiss, J.⁷

10
- 33846931755
- B. M. van Vugt-Lussenburg, E. Stjernschantz, J. Lastdrager, C. Oostenbrink, N. P. Vermeulen, J. N. Commandeur, J. Med. Chem. 2007, 50, 455.
- (2007) J. Med. Chem. , vol.50 , pp. 455
- van Vugt-Lussenburg, B.M.¹ Stjernschantz, E.² Lastdrager, J.³ Oostenbrink, C.⁴ Vermeulen, N.P.⁵ Commandeur, J.N.⁶

11
- 65649123015
- J. Dietrich, Y. Yoshikuni, K. Fisher, F. Woolard, D. Ockey, D. McPhee, N. Renninger, M. Chang, D. Baker, J. D. Keasling, ACS Chem. Biol. 2009, 4, 261.
- (2009) ACS Chem. Biol. , vol.4 , pp. 261
- Dietrich, J.¹ Yoshikuni, Y.² Fisher, K.³ Woolard, F.⁴ Ockey, D.⁵ McPhee, D.⁶ Renninger, N.⁷ Chang, M.⁸ Baker, D.⁹ Keasling, J.D.¹⁰

12
- 77950941685
- S. H. Park, D. H. Kim, D. Kim, H. C. Jung, J. G. Pan, T. Ahn, C. H. Yun, Drug Metab. Dispos. 2010, 38, 732.
- (2010) Drug Metab. Dispos. , vol.38 , pp. 732
- Park, S.H.¹ Kim, D.H.² Kim, D.³ Jung, H.C.⁴ Pan, J.G.⁵ Ahn, T.⁶ Yun, C.H.⁷

13
- 0027326717
- K. G. Ravichandran, S. S. Boddupalli, C. A. Hasermann, J. A. Peterson, J. Deisenhofer, Science 1993, 261, 731.
- (1993) Science , vol.261 , pp. 731
- Ravichandran, K.G.¹ Boddupalli, S.S.² Hasermann, C.A.³ Peterson, J.A.⁴ Deisenhofer, J.⁵

14
- 0029137990
- H. Li, T. L. Poulos, Acta Crystallogr. Sect. D Biol. Crystallogr. 1995, 51, 21.
- (1995) Acta Crystallogr. Sect. D Biol. Crystallogr. , vol.51 , pp. 21
- Li, H.¹ Poulos, T.L.²

15
- 33846958772
- H. M. Girvan, H. E. Seward, H. S. Toogood, M. R. Cheesman, D. Leys, A. W. Munro, J. Biol. Chem. 2007, 282, 564.
- (2007) J. Biol. Chem. , vol.282 , pp. 564
- Girvan, H.M.¹ Seward, H.E.² Toogood, H.S.³ Cheesman, M.R.⁴ Leys, D.⁵ Munro, A.W.⁶

16
- 0031013972
- H. Li, T. L. Poulos, Nat. Struct. Biol. 1997, 4, 140.
- (1997) Nat. Struct. Biol. , vol.4 , pp. 140
- Li, H.¹ Poulos, T.L.²

17
- 0035856545
- D. C. Haines, D. R. Tomchick, M. Machius, J. A. Peterson, Biochemistry 2001, 40, 13456.
- (2001) Biochemistry , vol.40 , pp. 13456
- Haines, D.C.¹ Tomchick, D.R.² Machius, M.³ Peterson, J.A.⁴

18
- 0028861062
- H. Yeom, S. G. Sligar, H. Li, T. L. Poulos, A. J. Fulco, Biochemistry 1995, 34, 14733.
- (1995) Biochemistry , vol.34 , pp. 14733
- Yeom, H.¹ Sligar, S.G.² Li, H.³ Poulos, T.L.⁴ Fulco, A.J.⁵

19
- 0345098305
- T. W. Ost, J. Clark, C. G. Mowat, C. S. Miles, M. D. Walkinshaw, G. A. Reid, S. K. Chapman, S. Daff, J. Am. Chem. Soc. 2003, 125, 15010.
- (2003) J. Am. Chem. Soc. , vol.125 , pp. 15010
- Ost, T.W.¹ Clark, J.² Mowat, C.G.³ Miles, C.S.⁴ Walkinshaw, M.D.⁵ Reid, G.A.⁶ Chapman, S.K.⁷ Daff, S.⁸

20
- 34748851229
- W. C. Huang, A. C. Westlake, J. D. Marechal, M. G. Joyce, P. C. Moody, G. C. Roberts, J. Mol. Biol. 2007, 373, 633.
- (2007) J. Mol. Biol. , vol.373 , pp. 633
- Huang, W.C.¹ Westlake, A.C.² Marechal, J.D.³ Joyce, M.G.⁴ Moody, P.C.⁵ Roberts, G.C.⁶

21
- 58249083277
- H. M. Girvan, H. S. Toogood, R. E. Littleford, H. E. Seward, W. E. Smith, I. S. Ekanem, D. Leys, M. R. Cheesman, A. W. Munro, Biochem. J. 2009, 417, 65.
- (2009) Biochem. J. , vol.417 , pp. 65
- Girvan, H.M.¹ Toogood, H.S.² Littleford, R.E.³ Seward, H.E.⁴ Smith, W.E.⁵ Ekanem, I.S.⁶ Leys, D.⁷ Cheesman, M.R.⁸ Munro, A.W.⁹

22
- 77951241302
- H. M. Girvan, C. W. Levy, P. Williams, K. Fisher, M. R. Cheesman, S. E. Rigby, D. Leys, A. W. Munro, Biochem. J. 2010, 427, 455.
- (2010) Biochem. J. , vol.427 , pp. 455
- Girvan, H.M.¹ Levy, C.W.² Williams, P.³ Fisher, K.⁴ Cheesman, M.R.⁵ Rigby, S.E.⁶ Leys, D.⁷ Munro, A.W.⁸

23
- 70349556438
- C. J. Whitehouse, S. G. Bell, W. Yang, J. A. Yorke, C. F. Blanford, A. J. Strong, E. J. Morse, M. Bartlam, Z. Rao, L. L. Wong, ChemBioChem 2009, 10, 1654.
- (2009) ChemBioChem , vol.10 , pp. 1654
- Whitehouse, C.J.¹ Bell, S.G.² Yang, W.³ Yorke, J.A.⁴ Blanford, C.F.⁵ Strong, A.J.⁶ Morse, E.J.⁷ Bartlam, M.⁸ Rao, Z.⁹ Wong, L.L.¹⁰

24
- 39549111087
- C. J. Whitehouse, S. G. Bell, H. G. Tufton, R. J. Kenny, L. C. Ogilvie, L. L. Wong, Chem. Commun. 2008, 966.
- (2008) Chem. Commun. , pp. 966
- Whitehouse, C.J.¹ Bell, S.G.² Tufton, H.G.³ Kenny, R.J.⁴ Ogilvie, L.C.⁵ Wong, L.L.⁶

25
- 57149138588
- C. J. Whitehouse, S. G. Bell, L. L. Wong, Chem. Eur. J. 2008, 14, 10905.
- (2008) Chem. Eur. J. , vol.14 , pp. 10905
- Whitehouse, C.J.¹ Bell, S.G.² Wong, L.L.³

26
- 0028267490
- C. A. Hasemann, K. G. Ravichandran, J. A. Peterson, J. Deisenhofer, J. Mol. Biol. 1994, 236, 1169.
- (1994) J. Mol. Biol. , vol.236 , pp. 1169
- Hasemann, C.A.¹ Ravichandran, K.G.² Peterson, J.A.³ Deisenhofer, J.⁴

27
- 33745410011
- J. P. Clark, C. S. Miles, C. G. Mowat, M. D. Walkinshaw, G. A. Reid, S. N. Daff, S. K. Chapman, J. Inorg. Biochem. 2006, 100, 1075.
- (2006) J. Inorg. Biochem. , vol.100 , pp. 1075
- Clark, J.P.¹ Miles, C.S.² Mowat, C.G.³ Walkinshaw, M.D.⁴ Reid, G.A.⁵ Daff, S.N.⁶ Chapman, S.K.⁷

28
- 0033514990
- I. F. Sevrioukova, H. Li, H. Zhang, J. A. Peterson, T. L. Poulos, Proc. Natl. Acad. Sci. USA 1999, 96, 1863.
- (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 1863
- Sevrioukova, I.F.¹ Li, H.² Zhang, H.³ Peterson, J.A.⁴ Poulos, T.L.⁵

29
- 0038136970
- D. Leys, C. G. Mowat, K. J. McLean, A. Richmond, S. K. Chapman, M. D. Walkinshaw, A. W. Munro, J. Biol. Chem. 2003, 278, 5141.
- (2003) J. Biol. Chem. , vol.278 , pp. 5141
- Leys, D.¹ Mowat, C.G.² McLean, K.J.³ Richmond, A.⁴ Chapman, S.K.⁵ Walkinshaw, M.D.⁶ Munro, A.W.⁷

30
- 0026542989
- O. Gotoh, J. Biol. Chem. 1992, 267, 83.
- (1992) J. Biol. Chem. , vol.267 , pp. 83
- Gotoh, O.¹

31
- 61449134084
- A. Seifert, J. Pleiss, Proteins Struct. Funct. Bioinf. 2009, 74, 1028.
- (2009) Proteins Struct. Funct. Bioinf. , vol.74 , pp. 1028
- Seifert, A.¹ Pleiss, J.²

32
- 77949270300
- C. K. Chen, R. E. Berry, T. Shokhireva, M. B. Murataliev, H. Zhang, F. A. Walker, J. Biol. Inorg. Chem. 2010, 15, 159.
- (2010) J. Biol. Inorg. Chem. , vol.15 , pp. 159
- Chen, C.K.¹ Berry, R.E.² Shokhireva, T.³ Murataliev, M.B.⁴ Zhang, H.⁵ Walker, F.A.⁶

33
- 0028956684
- M. D. Paulsen, R. L. Ornstein, Protein J. 1995, 21, 237.
- (1995) Protein J. , vol.21 , pp. 237
- Paulsen, M.D.¹ Ornstein, R.L.²

34
- 0029876059
- S. Modi, M. J. Sutcliffe, W. U. Primrose, L. Y. Lian, G. C. Roberts, Nat. Struct. Biol. 1996, 3, 414.
- (1996) Nat. Struct. Biol. , vol.3 , pp. 414
- Modi, S.¹ Sutcliffe, M.J.² Primrose, W.U.³ Lian, L.Y.⁴ Roberts, G.C.⁵

35
- 25844447810
- T. Jovanovic, R. Farid, R. A. Friesner, A. E. McDermott, J. Am. Chem. Soc. 2005, 127, 13548.
- (2005) J. Am. Chem. Soc. , vol.127 , pp. 13548
- Jovanovic, T.¹ Farid, R.² Friesner, R.A.³ McDermott, A.E.⁴

36
- 0030057886
- A. W. Munro, S. Daff, J. R. Coggins, J. G. Lindsay, S. K. Chapman, Eur. J. Biochem. 1996, 239, 403.
- (1996) Eur. J. Biochem. , vol.239 , pp. 403
- Munro, A.W.¹ Daff, S.² Coggins, J.R.³ Lindsay, J.G.⁴ Chapman, S.K.⁵

37
- 0016738181
- Y. Miura, A. J. Fulco, Biochim. Biophys. Acta. 1975, 388, 305.
- (1975) Biochim. Biophys. Acta. , vol.388 , pp. 305
- Miura, Y.¹ Fulco, A.J.²

38
- 33751396914
- M. J. Cryle, N. J. Matovic, J. J. De Voss, Tetrahedron Lett. 2007, 48, 133.
- (2007) Tetrahedron Lett. , vol.48 , pp. 133
- Cryle, M.J.¹ Matovic, N.J.² De Voss, J.J.³

39
- 33845379583
- M. T. Fisher, S. G. Sligar, J. Am. Chem. Soc. 1985, 107, 5018.
- (1985) J. Am. Chem. Soc. , vol.107 , pp. 5018
- Fisher, M.T.¹ Sligar, S.G.²

40
- 0032980919
- M. J. Honeychurch, A. O. Hill, L. L. Wong, FEBS Lett. 1999, 451, 351.
- (1999) FEBS Lett. , vol.451 , pp. 351
- Honeychurch, M.J.¹ Hill, A.O.² Wong, L.L.³

41
- 0001851317
- T. L. Poulos, J. Biol. Inorg. Chem. 1996, 1, 356.
- (1996) J. Biol. Inorg. Chem. , vol.1 , pp. 356
- Poulos, T.L.¹

42
- 57749112105
- K. J. McLean, P. Carroll, D. G. Lewis, A. J. Dunford, H. E. Seward, R. Neeli, M. R. Cheesman, L. Marsollier, P. Douglas, W. E. Smith, I. Rosenkrands, S. T. Cole, D. Leys, T. Parish, A. W. Munro, J. Biol. Chem. 2008, 283, 33406.
- (2008) J. Biol. Chem. , vol.283 , pp. 33406
- McLean, K.J.¹ Carroll, P.² Lewis, D.G.³ Dunford, A.J.⁴ Seward, H.E.⁵ Neeli, R.⁶ Cheesman, M.R.⁷ Marsollier, L.⁸ Douglas, P.⁹ Smith, W.E.¹⁰ Rosenkrands, I.¹¹ Cole, S.T.¹² Leys, D.¹³ Parish, T.¹⁴ Munro, A.W.¹⁵

43
- 33845252049
- B. OuYang, S. S. Pochapsky, G. M. Pagani, T. C. Pochapsky, Biochemistry 2006, 45, 14379.
- (2006) Biochemistry , vol.45 , pp. 14379
- OuYang, B.¹ Pochapsky, S.S.² Pagani, G.M.³ Pochapsky, T.C.⁴

44
- 36148958632
- Angew. Chem. Int. Ed.
- R. Fasan, M. M. Chen, N. C. Crook, F. H. Arnold, Angew. Chem. 2007, 119, 8566; Angew. Chem. Int. Ed. 2007, 46, 8414.
- (2007) Angew. Chem. 2007, 119, 8566; , vol.46 , pp. 8414
- Fasan, R.¹ Chen, M.M.² Crook, N.C.³ Arnold, F.H.⁴

45
- 0004136246
- Molecular Cloning: A Laboratory Manual
- 2nd ed., Cold Spring Harbor Laboratory Press, New York
- J. Sambrook, E. F. Fritsch, T. Maniatis, Molecular Cloning: A Laboratory Manual, 2nd ed., Cold Spring Harbor Laboratory Press, New York, 1989.
- (1989)
- Sambrook, J.¹ Fritsch, E.F.² Maniatis, T.³

46
- 50449100139
- T. Omura, R. Sato, J. Biol. Chem. 1964, 239, 2379.
- (1964) J. Biol. Chem. , vol.239 , pp. 2379
- Omura, T.¹ Sato, R.²

47
- 70450094008
- F. Xu, S. G. Bell, Y. Peng, E. O. Johnson, M. Bartlam, Z. Rao, L. L. Wong, Proteins Struct. Funct. Bioinf. 2009, 77, 867.
- (2009) Proteins Struct. Funct. Bioinf. , vol.77 , pp. 867
- Xu, F.¹ Bell, S.G.² Peng, Y.³ Johnson, E.O.⁴ Bartlam, M.⁵ Rao, Z.⁶ Wong, L.L.⁷

48
- 0035856564
- T. W. Ost, C. S. Miles, A. W. Munro, J. Murdoch, G. A. Reid, S. K. Chapman, Biochemistry 2001, 40, 13421.
- (2001) Biochemistry , vol.40 , pp. 13421
- Ost, T.W.¹ Miles, C.S.² Munro, A.W.³ Murdoch, J.⁴ Reid, G.A.⁵ Chapman, S.K.⁶

49
- 0031059866
- Z. Otwinowski, W. Minor, Methods Enzymol. 1997, 276, 307.
- (1997) Methods Enzymol. , vol.276 , pp. 307
- Otwinowski, Z.¹ Minor, W.²

50
- 34447508216
- A. J. McCoy, R. W. Grosse-Kunstleve, P. D. Adams, M. D. Winn, L. C. Storoni, R. J. Read, J. Appl. Crystallogr. 2007, 40, 658.
- (2007) J. Appl. Crystallogr. , vol.40 , pp. 658
- McCoy, A.J.¹ Grosse-Kunstleve, R.W.² Adams, P.D.³ Winn, M.D.⁴ Storoni, L.C.⁵ Read, R.J.⁶

51
- 0028103275
- Collaborative Computational Project, Number 4, Acta Crystallogr. Sect. D Biol. Crystallogr. 1994, 50, 760.
- (1994) Acta Crystallogr. Sect. D Biol. Crystallogr. , vol.50 , pp. 760
- Project, C.C.¹ 4, N.²

52
- 13244281317
- P. Emsley, K. Cowtan, Acta Crystallogr. Sect. D Biol. Crystallogr. 2004, 60, 2126.
- (2004) Acta Crystallogr. Sect. D Biol. Crystallogr. , vol.60 , pp. 2126
- Emsley, P.¹ Cowtan, K.²

53
- 0030924992
- G. N. Murshudov, A. A. Vagin, E. J. Dodson, Acta Crystallogr. Sect. D Biol. Crystallogr. 1997, 53, 240.
- (1997) Acta Crystallogr. Sect. D Biol. Crystallogr. , vol.53 , pp. 240
- Murshudov, G.N.¹ Vagin, A.A.² Dodson, E.J.³

54
- 0000243829
- R. A. Laskowski, M. W. Macarthur, D. S. Moss, J. M. Thornton, J. Appl. Crystallogr. 1993, 26, 283.
- (1993) J. Appl. Crystallogr. , vol.26 , pp. 283
- Laskowski, R.A.¹ Macarthur, M.W.² Moss, D.S.³ Thornton, J.M.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.