Gene silencing of STAT6 with siRNA ameliorates contact hypersensitivity and allergic rhinitis

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 66, Issue 1, 2011, Pages 124-131

  Hosoya, K ^a   Satoh, T ^a   Yamamoto, Y ^a   Saeki, K ^a   Igawa, K ^a   Okano, M ^b   Moriya, T ^c   Imamura, O ^c   Nemoto, Y ^c   Yokozeki, H ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c HaploPharma Inc   (Japan)

Author keywords

contact sensitivity; eotaxin; lipofectamine; nasal allergy; siRNA; STAT6

Indexed keywords

EOTAXIN; HAPTEN; INTERLEUKIN 13; INTERLEUKIN 4; MACROPHAGE DERIVED CHEMOKINE; NUCLEOTIDE; SMALL INTERFERING RNA; STAT6 PROTEIN; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TUMOR NECROSIS FACTOR ALPHA;

ALLERGIC RHINITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL INFILTRATION; CELLULAR IMMUNITY; CONTACT ALLERGY; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; GROWTH INHIBITION; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; LYMPH NODE CELL; MEDIATOR; MOUSE; NONHUMAN; NOSE MUCOSA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SKIN FIBROBLAST; SNEEZING; TH2 CELL;

ANIMALS; BASE SEQUENCE; CHEMOKINE CCL11; DERMATITIS, CONTACT; DISEASE MODELS, ANIMAL; FIBROBLASTS; GENE SILENCING; HUMANS; HYPERSENSITIVITY; INTERLEUKIN-4; LIPIDS; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; NIH 3T3 CELLS; RHINITIS; RNA, SMALL INTERFERING; STAT6 TRANSCRIPTION FACTOR; TH2 CELLS; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 78649995661     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2010.02440.x     Document Type: Article

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