Development of Effector CD8+ T Cells in Contact Hypersensitivity Occurs Independently of CD4+ T Cells

Journal of Immunology

Volumn 158, Issue 10, 1997, Pages 4721-4728

  Xu, Hui ^a   Banerjee, Arjun ^a   Dilulio, Nancy A ^a   Fairchild, Robert L ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HAPTEN; HERMES ANTIGEN; INTERLEUKIN 4; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

ANIMAL; ANTIGEN PRESENTING CELL; ARTICLE; BAGG ALBINO MOUSE; BIOSYNTHESIS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTACT DERMATITIS; EPIDERMIS; FEMALE; IMMUNOLOGY; IMMUNOPHENOTYPING; LANGERHANS CELL; LYMPHOCYTE DEPLETION; LYMPHOCYTE FUNCTION; METABOLISM; MOUSE; TH1 CELL; TH2 CELL; TIME;

ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD44; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DERMATITIS, CONTACT; EPIDERMIS; FEMALE; HAPTENS; IMMUNITY, CELLULAR; IMMUNOPHENOTYPING; INTERFERON TYPE II; INTERLEUKIN-4; LANGERHANS CELLS; LYMPHOCYTE COOPERATION; LYMPHOCYTE DEPLETION; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MICE; MICE, INBRED BALB C; TH1 CELLS; TH2 CELLS; TIME FACTORS;

EID: 0031570104     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Buller, R. M. L., K. L. Holmes, A. Hugin, T. N. Frederickson, and H. C. Morse III. 1987. Induction of cytotoxic T-cell responses in vivo in the absence of CD4 helper cells. Nature 328:77.
2. + T cell lineage to mount an effective tumoricidal response to syngeneic tumor-bearing novel class I MHC antigens. J. Immunol. 143:4287.
3. Sprent, J., and M. Schaefer. 1985. Properties of purified T cell subsets. I. In vitro responses to class I vs class II H-2 alloantigens. J. Exp. Med. 162:2068.
4. + T lymphocytes. J. Immunol. 151: 5993.
5. Cai, Z., and J. Sprent. 1994. Resting and activated T cells display different requirements for CD8 molecules. J. Exp. Med. 179:2005.
6. + cells in the generation of killer activity. J. Exp. Med. 141:1390.
7. + T ceils to cell proliferation and cytolytic activity. J. Exp. Med. 148:1523.
8. + T cell in allograft rejection. J. Immunol. 139:4022.
9. Rosenberg, A. S., T. Mizuochi, S. O. Sharrow, and A. Singer. 1987. Phenotype, specificity, and function of T cell subsets and T cell interactions involved in skin allograft rejection. J. Exp. Med. 165:1296.
10. Keene, J., and J. Forman. 1982. Helper activity is required for the in vivo generation of cytotoxic T lymphocytes. J. Exp. Med. 155:768.
11. Mitchison, N. A. 1983. Linked help in the cytotoxic T cell response revealed by adoptive transfer. Transplant. Proc. 15:2121.
12. Gill, R. G. 1993. T-cell-T-cell collaboration in allograft responses. Curr. Opin. Immunol. 5:782.
13. Prystowsky, M. B., J. M. Ely, D. I. Beller, L. Eisenber, J. Goldman, M. Goldman, E. Goldwasser, J. Ihle, J. Quintans, H. Remold, S. N. Vogel, and F. W. Fitch. 1982. Alloreactive cloned T cell lines. VI. Multiple lymphokine activities secreted by helper and cytolytic cloned T lymphocytes. J. Immunol. 129:2337.
14. + T cell clones secrete the Th1 pattern of cytokines. J. Immunol. 144:1744.
15. + T cells. J. Exp. Med. 183:1001.
16. + T cell development from regulatory Th2 to effector Th1 cells alters the contact hypersensitivity response. Eur. J. Immunol. 26:2606.
17. Cobbold, S. P., A. Jayasuriya, A. Nash, T. Prospero, and H. Waldmann. 1985. Therapy with monoclonal antibodies by elimination of T-cell subsets in-vivo. Nature 312:548.
18. Kubo, R. T., W. Born, J. W. Kappler, P. Marrack, and M. Pigeon. 1989. Characterization of a monoclonal antibody which detects all murine αβ T cell receptors. J. Immunol. 142:2736.
19. Kappler, J. W., N. Roehm, and P. Marrack. 1987. T cell tolerance by clonal elimination in the thymus. Cell 49:273.
20. Fairchild, R. L., E. Palmer, and J. W. Moorhead. 1993. Production of DNP-specific/class I MHC-restricted suppressor molecules is linked to the expression of T cell receptor α- and β-chain genes. J. Immunol. 150:67.
21. Bigby, M., R. Vargas, and M.-S. Sy. 1989. Production of hapten-specific T cell hybridomas and their use to study the effect of ultraviolet B irradiation on the development of contact hypersensitivity. J. Immunol. 143:3867.
22. Macatonia, S. E., A. J. Edwards, and S. C. Knight. 1986. Dendritic cells and the initiation of contact sensitivity to fluorescein isothiocyanate. Immunology 59:509.
23. Kripke, M., C. Munn, A. Jeevan, J. Tang, and S. Bucana. 1990. Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization. J. Immunol. 145:2833.
24. Cher, D. J., and T. R. Mosmann. 1987. Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by Th1 clone. J. Immunol. 138: 3688.
25. Hauser, C. 1990. Cultured epidermal Langerhans cells activate effector T cells for contact sensitivity. J. Invest. Dermatol. 95:436.
26. Kalish, R. S., and K. L. Johnson. 1990. Enrichment and function of urushiol (poison ivy)-specific T lymphocytes in lesions of allergic contact dermatitis to urushiol. J. Immunol. 145:3706.
27. + T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion. J. Immunol. 144:4121.
28. + T cells during the elicitation of contact hypersensitivity. J. Invest. Dermatol. 107:360.
29. + T cells through IL-12 produced by Listeria-induced macrophages. Science 260:547.
30. + T cells to enhance priming for IFNγ production and diminishes IL-4 inhibition on such priming. Proc. Natl. Acad. Sci. USA 90:10188.
31. Kuchroo, V. K., M. P. Das, J. A. Brown, A. M. Ranger, S. S. Zamvil, R. A. Sobel, H. L. Weiner, N. Nabavi, and L. H. Glimcher. 1995. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 80:707.
32. Freeman, G. J., V. A. Boussiotis, A. Anumanthan, G. M. Bernstein, X.-Y. Ke, R. D. Rennert, G. S. Gray, J. G. Gribben, and L. M. Nadler. 1995. B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4. Immunity 2:523.
33. + T cells. J. Exp. Med. 182:1591.
34. + T helper cell phenoytpe development in a T cell receptor-αβ-transgenic model. J. Exp. Med. 182:1579.
35. Springer, T. A. 1990. Adhesion receptors of the immune system. Nature 346:425.
36. Budd, R. C., J. C. Cerottini, C. Horvatch, C. Bron, T. Pedrazzini, R. C. Howe, and H. R. MacDonald. 1987. Distinction of virgin and memory T lymphocytes: stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation. J. Immunol. 138:3120.
37. MEL-14 (LECAM-1), Pgp-1, LFA-1, and VLA-4α during the differentiation of cytotoxic T lymphocytes induced by allografts. J. Immunol. 148:2348.
38. Scheynius, A., R. L. Camp, and E. Pure. 1993. Reduced contact sensitivity reactions in mice treated with monoclonal antibodies to leukocyte function-associated molecule-1 and intercellular adhesion molecule-1. J. Immunol. 150:655.
39. Camp, R. L., A. Scheynius, C. Johanssson, and E. Pure. 1993. CD44 is necessary for optimal contact allergic responses but is not required for normal leukocyte extravasation. J. Exp. Med. 178:497.
40. 2+ helper T cells initiate cytotoxic T lymphocyte responses against allogeneic major histocompatabilily antigens but not against trinitrophenyl-modified self. J. Exp. Med. 162:427.
41. Butler, L., and J. R. Battisto. 1979. In vivo generation of hapten-specific killer T cells without elimination of suppressor cells. J. Immunol. 122:1578.
42. + cytotoxic T lymphocytes by dendritic cells. J. Exp. Med. 166:182.
43. Bergstresser, P. R., G. B. Toews, J. N. Gilliam, and J. W. Streilein. 1980. Unusual numbers and distribution of Langerhans cells in skin with unique immunologic properties. J. Invest. Dermatol. 74:312.
44. Chen, H.-D., and W. K. Silvers. 1983. Influence of Langerhans cells on the survival of H-Y incompatible skin grafts in rodents. J. Invest. Dermatol. 81:20.
45. Lafferty, K. L., and A. J. Cunningham. 1975. A new analysis of allogeneic interactions. Austr. J. Exp. Biol. Med. Sci. 53:27.