Pathogenic Mechanisms Underlying the Clinical Symptoms of Allergic Rhinitis

American Journal of Rhinology

Volumn 14, Issue 5, 2000, Pages 325-333

  Wang, De Yun ^a   Clement, Peter ^b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN;

HAY FEVER; HUMAN; IMMUNOLOGY; NOSE MUCOSA; PERENNIAL RHINITIS; REVIEW;

ALLERGENS; HUMANS; NASAL MUCOSA; RHINITIS, ALLERGIC, PERENNIAL; RHINITIS, ALLERGIC, SEASONAL;

EID: 0034279329     PISSN: 10506586     EISSN: None     Source Type: Journal    
DOI: 10.2500/105065800781329483     Document Type: Article

References (28)

1. Costa JJ, Weller PF, and Galli SJ. The cells of the allergic response: mast cells, basophils and eosinophils. JAMA 278: 1815-1822, 1997.
2. Gallis SJ. New concepts about the mast cell. N Engl J Med 328:257-265, 1993.
3. Wang DY, Clement P, Smitz J, et al. Correlations between complaints, inflammatory cells and mediators after nasal allergen challenge and during natural allergen exposure. Int Arch Allergy Immunol 106:278-285, 1995.
4. Wang D, Smitz J, and Clement P. Prostaglandin D2 measurement in nasal secretions is not a reliable marker for mast cell activation in atopic patient. Clin Exp Allergy 25 1228-1234, 1995.
5. Wang D, Smitz J, Derde M-P, and Clement P. Concentrations of myeloperoxidase in nasal secretions of atopic patients after nasal allergen challenge and during the natural allergen exposure. Int Arch Allergy Immunol 110:85-90, 1996.
6. 2 antagonists on nasal symptoms and mediator release in atopic patients after nasal allergen challenge during the pollen season Acta Otolaryngologica (Stockh); 116:91-96, 1996.
7. Wang DY, Smitz J, De Waele M, and Clement P. Effect of topical applications of budesonide and azelastine on nasal symptoms, eosinophil count and mediator release in atopic patients after nasal allergen challenge during the pollen season. Int Arch Allergy Immunol 114:185-192, 1997.
8. Wang DY, Duyck F, Smitz J, and Clement P. Efficacy and onset of action of fluticasone propionate aqueous nasal spray on nasal symptoms, eosinophil count, and mediator release after nasal allergen challenge in patients with seasonal allergic rhinitis. Allergy 53:375-382, 1998.
9. Naclerio RM, Proud D, Togias AG, et al. Inflammatory mediators in late antigen-induced rhinitis. N Engl J Med 313:65-70, 1985,
10. Naclerio RM, Meier HL, Kagey-Sobotka A, et al. Mediator release after nasal airway challenge with allergen. Am Respir Dis 128:597-602, 1983.
11. Juliusson S, Holmberg K, Baumgarten CR, et al. Tryptase in nasal lavage fluid after local allergen challenge. Allergy 46:459-465, 1991.
12. Rasp G, and Hochstrasser K. Tryptase in nasal fluid is a useful marker of allergic rhinitis. Allergy 48:72-74, 1993.
13. Creticos PS, Peters SP, Adkinson NF, et al. Peptide leukotriene release after antigen challenge in patients sensitive to ragweed, N Engl J Med 310:1626-1630, 1984.
14. Bisgaard H, Romeling F, Mygind N, et al. Measurement of LTC4 and histamine in nasal lavage fluid. In Allergic and Vasomotor Rhinitis: Pathophysiological Aspects. Mygind N, Pipkorn U and Dahl R (Eds), Munksgaard, Copenhagen, 189-197, 1987.
15. Wang D, Clement P, Smitz J, and Derde M-P. Concentrations of chemical mediators in nasal secretions after nasal allergen challenges in atopic patients. Eur Arch Otorhinolaryngol 252(Suppl): S40-S43, 1995.
16. Wang D, and Clement P. Assessment of early and late phase nasal obstruction in atopic patients after nasal allergen challenge. Clin Otolaryngol 20:368-373, 1995.
17. Wang DJ, Smitz L, Waterschoot S, and Clement P. An approach to the understanding of the nasal early-phase reaction induced by nasal allergen challenge. Allergy 52:162-167, 1997.
18. Bascom R, Pipkorn U, Lichtenstein LM, and Lerio RM. The influx of inflammatory cells into nasal washings during the late response to antigen challenge: effect of systemic steroid pretreatment. Am Rev Respir Dis 138:406-412, 1988.
19. Pelikan Z, and Pelikan-Filipek M. Cytologic changes in the nasal secretions during the late nasal response. J Allergy Clin Immunol 83:1068-1079, 1989.
20. Iliopoulos O, Proud D, Adkinson NF, et al. Relationship between the early, late, and rechallenge reaction to nasal challenge with antigen: observation on the role of inflammatory mediators and cells. J Allergy Clin Immunol 86:851-861, 1990.
21. Venge P. Eosinophil and neutrophil granulocytes. Allergy 48: 39-47, 1993.
22. Venge P, Hakansson L, Rak S, et al. Inflammatory cells in asthma an rhinitis. In Rhinitis and Asthma. Mygind N, Pipkorn U. and Dahl R (Eds) Munksgaard, Copenhagen, 188-202, 1990.
23. Connell JT. Quantitative intranasal pollen challenge. II Effect of daily pollen challenge, environmental pollen exposure, and placebo challenge on the nasal membrane. J Allergy 41.123-139, 1968.
24. Linder A, Strandberg K, and Deuschl H. Variations in histamine concentration in nasal secretions in patients with allergic rhinitis. Allergy 43:119-126, 1988.
25. Dorsch W, and Strasser Th. Leukotrienes. In Late Phase Allergic Reactions. Dorsch W. (Ed.) CRC Press, Boca Raton, FL 59-64, 1990.
26. Adolphson CR, and Gleich GJ. Eosinophils. In Allergy. Holgate T, and Church MK (Eds.) Gower Medical Publishing, London, 6.1-6.12, 1993.
27. Linder A, Verge P, and Deuschl H. Eosinophil cationic protein and myeloperoxidase in nasal secretion as markers of inflammation in allergic rhinitis. Allergy 42:583-590, 1987.
28. Bentley AM, Jacobson MR, Cumberworth V, et al. Immunohistology of the nasal mucosa in seasonal allergic rhinitis: increases in activated eosinophils and epithelia mast cells. J Allergy Clin Immunol 89:877-883, 1992.