Nitric oxide modulates mechanical strain-induced activation of p38 MAPK in mesangial cells

American Journal of Physiology - Renal Physiology

Volumn 279, Issue 2 48-2, 2000, Pages

  Ingram, A J ^a,c   James, L ^b   Thai, K ^b   Ly, H ^b   Cai, L ^b   Scholey, J W ^b  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c NONE   (Canada)

Author keywords

Kidney glomerulus; Mitogen activated protein kinases; Nuclear factor B; Physical forces; Signaling

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 8 BROMO CYCLIC GMP; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LINSIDOMINE; MITOGEN ACTIVATED PROTEIN KINASE; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; NITRIC OXIDE DONOR; SYNAPTOPHYSIN;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; GLOMERULUS CAPILLARY; MECHANICAL STRESS; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION;

EID: 0033850615     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.2000.279.2.f243     Document Type: Article

References (39)

1. Mechanical stretch/relaxation of cultured rat mesangial cells induces protooncogenes and cyclooxygenase
2. Control of glomerular hypertension limits glomerular injury in rats with reduced renal mass
3. Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
4. Hemodynamically mediated glomerular injury and the progressive nature of kidney disease
5. Rapid and delayed p42/p44 mitogen-activated protein kinase activation by nitric oxide: The role of cyclic GMP and tyrosine phosphatase inhibition
6. Nitric oxide regulates shear stress-induced early growth response-1. Expression via the extracellular signal-regulated kinase pathway in endothelial cells
7. Stimulation of 'stress-regulated' mitogen-activated protein kinases (stress-activated protein kinases/c-Jun N-terminal kinases and p38-mitogen-activated protein kinases) in perfused rat hearts by oxidative and other stresses
8. The mitogen-activated protein kinase signal transduction pathway
9. Glomerular injury in unine-phrectomized spontaneously hypertensive rats. A consequence of glomerular capillary hypertension
10. Hemodynamic basis for glomerular injury in rats with desoxycorticosterone-salt hypertension
11. 2-terminal kinase and p38 MAPK signal pathways in rat renal mesangial cells
12. Stretching mesangial cells stimulates tyrosine phosphorylation of focal adhesion kinase pp125fak
13. The role of physical forces in alterations of mesangial cell function
14. Continuous stretch-relaxation in culture alters rat mesangial cell morphology, growth characteristics, and metabolic activity
15. Tyrosine kinase dependent expression of TGF-beta induced by stretch in mesangial cells
16. Nitric oxide stimulates the stress activated protein kinase p38 in rat renal mesangial cells
17. Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways
18. Dietary supplementation with L-arginine limits cell proliferation in the remnant glomerulus
19. Activation of mesangial cell signaling cascades in response to mechanical strain
20. High pressure conditions promote the proliferation of rat cultured mesangial cells in vitro
21. Applied pressure enhances cell proliferation through mitogen-activated protein kinase activation in mesangial cells
22. Mechanical stretch induces hypertrophic responses in cardiac myocytes of angiotensin II type 1a receptor knockout mice
23. Activation of the NF-kappaB pathway by inflammatory stimuli in human neutrophils
24. Converting enzyme inhibitor therapy limits progressive glomerular injury in rats with renal insufficiency
25. The 1996 Albert Lasker Medical Research Awards. Signal transduction using nitric oxide and cyclic guanosine monophosphate
26. Selective activation and functional significance of p38alpha mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils
27. Activation of p38 mitogen-actirated protein kinase by PYK2/related adhesion focal tyrosine kinase-dependent mechanism
28. Nitric oxide stimulates stress-activated protein kinases in glomerular endothelial and mesangial cells
29. Dietary supplementation with L-arginine ameliorates the progression of renal disease in rats with subtotal nephrectomy
30. Intraglomerular pressure and mesangial stretching stimulate extracellular matrix formation in the rat
31. Regulation of NF-kappa B activation by MAP kinase cascades
32. p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor
33. Nitric N-acetylcysteine inhibit the activation of mitogen-activated protein kinases by angiotensin II in rat cardiac fibroblasts
34. Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family
35. Mechanical strain of rat vascular smooth muscle cells is sensed by specific extracellular matrix/integrin interactions
36. Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells
37. Alteration of cellular function in rat mesangial cells in response to mechanical stretch relaxation
38. Regulation of extracellular matrix by mechanical stress in rat glomerular mesangial cells
39. MKK6 activates myocardial cell NF-kappaB and inhibits apoptosis in a p38MAPK dependent manner