메뉴 건너뛰기




Volumn 19, Issue 10, 2010, Pages 650-655

Antiepileptic drug therapy the story so far

Author keywords

Antiepileptic drugs; Epilepsy; Mechanism of action; Pharmacoresistance; Prognosis

Indexed keywords

ANTICONVULSIVE AGENT; BENZODIAZEPINE DERIVATIVE; CARBAMAZEPINE; CHLORPROMAZINE; CLOBAZAM; CLONAZEPAM; COUMARIN DERIVATIVE; DIAZEPAM; ESLICARBAZEPINE ACETATE; ETHOSUXIMIDE; ETIRACETAM; FELBAMATE; GABAPENTIN; HARKOSERIDE; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; POTASSIUM BROMIDE; PREGABALIN; PRIMIDONE; RUFINAMIDE; STIRIPENTOL; TIAGABINE; TOPIRAMATE; TRIMETHADIONE; UNINDEXED DRUG; VALPROIC ACID; VIGABATRIN; ZONISAMIDE;

EID: 78649849971     PISSN: 10591311     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.seizure.2010.10.027     Document Type: Review
Times cited : (219)

References (65)
  • 1
    • 1842795410 scopus 로고
    • Experiments to determine the precise effect of bromide of potassium in epilepsy
    • T.S. Clouston Experiments to determine the precise effect of bromide of potassium in epilepsy J Ment Sci 1868 305 321
    • (1868) J Ment Sci , pp. 305-321
    • Clouston, T.S.1
  • 2
    • 34250342167 scopus 로고    scopus 로고
    • Pharmacology, efficacy and tolerability of potassium bromide in childhood Epilepsy
    • R. Korinthenberg, P. Bukart, C. Woefle, J.S. Moenting, and J.P. Ernst Pharmacology, efficacy and tolerability of potassium bromide in childhood Epilepsy J Child Neurol 22 2007 414 418
    • (2007) J Child Neurol , vol.22 , pp. 414-418
    • Korinthenberg, R.1    Bukart, P.2    Woefle, C.3    Moenting, J.S.4    Ernst, J.P.5
  • 3
    • 0001072003 scopus 로고
    • Luminal bei epilepsie
    • A. Hauptmann Luminal bei epilepsie Munch Med Wochenshr 59 1912 1907 1909
    • (1912) Munch Med Wochenshr , vol.59 , pp. 1907-1909
    • Hauptmann, A.1
  • 4
    • 4544312379 scopus 로고    scopus 로고
    • Phenobarbital for the treatment of epilepsy in the 21st century: A critical review
    • P. Kwan, and M.J. Brodie Phenobarbital for the treatment of epilepsy in the 21st century: a critical review Epilepsia 2004 1141 1149
    • (2004) Epilepsia , pp. 1141-1149
    • Kwan, P.1    Brodie, M.J.2
  • 5
    • 84942475840 scopus 로고
    • Sodium diphenylhydantonate in the treatment of convulsive disorders
    • H.H. Merritt, and T.J. Putnum Sodium diphenylhydantonate in the treatment of convulsive disorders JAMA 111 1938 1068 1075
    • (1938) JAMA , vol.111 , pp. 1068-1075
    • Merritt, H.H.1    Putnum, T.J.2
  • 6
    • 77649319457 scopus 로고    scopus 로고
    • Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy
    • T.A. Glauser, A. Cnaan, S. Shinnar, D.G. Hirtz, and D. Dlugos Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy N Engl J Med 362 2010 790 799
    • (2010) N Engl J Med , vol.362 , pp. 790-799
    • Glauser, T.A.1    Cnaan, A.2    Shinnar, S.3    Hirtz, D.G.4    Dlugos, D.5
  • 7
    • 33746124186 scopus 로고    scopus 로고
    • ILAE treatment guidelines: Evidence-based analysis of antiepileptic drug therapy and effectiveness as initial monotherapy for epileptic seizures and syndromes
    • T. Glauser, E. Ben-Menachem, B. Bourgeois, A. Cnaan, and D. Chadwick ILAE treatment guidelines: evidence-based analysis of antiepileptic drug therapy and effectiveness as initial monotherapy for epileptic seizures and syndromes Epilepsia 47 2006 1094 1120
    • (2006) Epilepsia , vol.47 , pp. 1094-1120
    • Glauser, T.1    Ben-Menachem, E.2    Bourgeois, B.3    Cnaan, A.4    Chadwick, D.5
  • 8
    • 73649173245 scopus 로고
    • Pharmacodynamic properties of dipropylactic acid. 1. Anticonvulsive action
    • H. Meunier, G. Carraz, Y. Meunier, P. Eymard, and M. Almarro Pharmacodynamic properties of dipropylactic acid. 1. Anticonvulsive action Therapie 18 1963 435 438
    • (1963) Therapie , vol.18 , pp. 435-438
    • Meunier, H.1    Carraz, G.2    Meunier, Y.3    Eymard, P.4    Almarro, M.5
  • 9
    • 0015699678 scopus 로고
    • Benzodiazepines in the treatment of epilepsy: A review
    • T.R. Browne, and J.K. Penry Benzodiazepines in the treatment of epilepsy: a review Epilepsia 14 1973 277 310
    • (1973) Epilepsia , vol.14 , pp. 277-310
    • Browne, T.R.1    Penry, J.K.2
  • 10
    • 0000401319 scopus 로고
    • Treatment of status epilepticus with diazepam (valium)
    • H. Gastaut, R. Naquet, R. Poiré, and A.C. Tassinari Treatment of status epilepticus with diazepam (valium) Epilepsia 6 1965 167 182
    • (1965) Epilepsia , vol.6 , pp. 167-182
    • Gastaut, H.1    Naquet, R.2    Poiré, R.3    Tassinari, A.C.4
  • 11
    • 0015120722 scopus 로고
    • Treatment of status epilepticus with a new benzodiazepine more active than diazepam
    • H. Gastaut, J. Courjon, R. Poiré, and M. Weber Treatment of status epilepticus with a new benzodiazepine more active than diazepam Epilepsia 12 1971 197 214
    • (1971) Epilepsia , vol.12 , pp. 197-214
    • Gastaut, H.1    Courjon, J.2    Poiré, R.3    Weber, M.4
  • 16
    • 58149215498 scopus 로고    scopus 로고
    • Lacosamide: Pharmacology, mechanisms of action and pooled efficacy and safety: Data in partial onset seizures
    • A. Beydoun, J. D'souza, D. Herbert, and P. Doty Lacosamide: pharmacology, mechanisms of action and pooled efficacy and safety: data in partial onset seizures Expert Rev Neurotherapeutics 9 2009 33 42
    • (2009) Expert Rev Neurotherapeutics , vol.9 , pp. 33-42
    • Beydoun, A.1    D'Souza, J.2    Herbert, D.3    Doty, P.4
  • 17
    • 33750045736 scopus 로고    scopus 로고
    • Combination therapy in epilepsy. When and what to use
    • P. Kwan, and M.J. Brodie Combination therapy in epilepsy. When and what to use Drugs 66 2006 1817 1829
    • (2006) Drugs , vol.66 , pp. 1817-1829
    • Kwan, P.1    Brodie, M.J.2
  • 18
    • 3042798891 scopus 로고    scopus 로고
    • The neurobiology of antiepileptic drugs
    • M.A. Rogawski, and W. Lscher The neurobiology of antiepileptic drugs Nat Rev Neurosci 5 2004 553 564
    • (2004) Nat Rev Neurosci , vol.5 , pp. 553-564
    • Rogawski, M.A.1    Lscher, W.2
  • 19
    • 68149096743 scopus 로고    scopus 로고
    • Rufinamide for the adjunctive treatment of partial seizures in adults and adolescents: A randomized placebo-controlled trial
    • M.J. Brodie, W.C. Rosenfeld, B. Vasquez, R. Sachdeo, and C. Perdomo Rufinamide for the adjunctive treatment of partial seizures in adults and adolescents: a randomized placebo-controlled trial Epilepsia 50 2009 1899 1909
    • (2009) Epilepsia , vol.50 , pp. 1899-1909
    • Brodie, M.J.1    Rosenfeld, W.C.2    Vasquez, B.3    Sachdeo, R.4    Perdomo, C.5
  • 20
    • 44949184519 scopus 로고    scopus 로고
    • Rufinamide for generalised seizures associated with Lennox-Gastaut syndrome
    • T. Glauser, G. Kluger, R. Sachdeo, G. Krauss, and C. Perdomo Rufinamide for generalised seizures associated with Lennox-Gastaut syndrome Neurology 70 2008 1950 1958
    • (2008) Neurology , vol.70 , pp. 1950-1958
    • Glauser, T.1    Kluger, G.2    Sachdeo, R.3    Krauss, G.4    Perdomo, C.5
  • 21
    • 33846188141 scopus 로고    scopus 로고
    • Molecular targets for antiepileptic drug development
    • B.S. Meldrum, and M.A. Rogawski Molecular targets for antiepileptic drug development Neurotherapeutics 4 2007 18 61
    • (2007) Neurotherapeutics , vol.4 , pp. 18-61
    • Meldrum, B.S.1    Rogawski, M.A.2
  • 22
    • 0035717677 scopus 로고    scopus 로고
    • Update on the mechanisms of action of epileptic drugs
    • G.J. Sills, and M.J. Brodie Update on the mechanisms of action of epileptic drugs Epileptic Disorders 3 2001 165 172
    • (2001) Epileptic Disorders , vol.3 , pp. 165-172
    • Sills, G.J.1    Brodie, M.J.2
  • 24
    • 33645851658 scopus 로고    scopus 로고
    • Refractory epilepsy: Mechanisms and solutions
    • P. Kwan, and M.J. Brodie Refractory epilepsy: mechanisms and solutions Expert Rev Neurotherapeutics 6 2006 397 406
    • (2006) Expert Rev Neurotherapeutics , vol.6 , pp. 397-406
    • Kwan, P.1    Brodie, M.J.2
  • 25
    • 74049163222 scopus 로고    scopus 로고
    • Key factors in the discovery and development of new antiepileptic drugs
    • M. Bialer, and H.S. White Key factors in the discovery and development of new antiepileptic drugs Nature Rev 9 2010 68 82
    • (2010) Nature Rev , vol.9 , pp. 68-82
    • Bialer, M.1    White, H.S.2
  • 26
    • 78951483902 scopus 로고    scopus 로고
    • Pharmacotherapy of epilepsy: Newly approved and developmental agents
    • in press
    • Stephen LJ, Brodie MJ. Pharmacotherapy of epilepsy: newly approved and developmental agents. CNS Drugs, in press.
    • CNS Drugs
    • Stephen, L.J.1    Brodie, M.J.2
  • 27
    • 70350159331 scopus 로고    scopus 로고
    • Selection of antiepileptic drugs in adults
    • L.J. Stephen, and M.J. Brodie Selection of antiepileptic drugs in adults Neurol Clin 27 2009 967 992
    • (2009) Neurol Clin , vol.27 , pp. 967-992
    • Stephen, L.J.1    Brodie, M.J.2
  • 28
    • 0038679502 scopus 로고    scopus 로고
    • Clinical trials of antiepileptic medications in newly diagnosed patients with epilepsy
    • P. Kwan, and M.J. Brodie Clinical trials of antiepileptic medications in newly diagnosed patients with epilepsy Neurology 60 Suppl 4 2003 S2 S12
    • (2003) Neurology , vol.60 , Issue.SUPPL. 4
    • Kwan, P.1    Brodie, M.J.2
  • 29
    • 33846850154 scopus 로고    scopus 로고
    • Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy
    • M.J. Brodie, E. Perucca, P. Ryvlin, E. Ben-Menachem, and H.J. Meencke Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy Neurology 68 2007 402 408
    • (2007) Neurology , vol.68 , pp. 402-408
    • Brodie, M.J.1    Perucca, E.2    Ryvlin, P.3    Ben-Menachem, E.4    Meencke, H.J.5
  • 30
    • 33947241772 scopus 로고    scopus 로고
    • The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine or topiramate for treatment of partial epilepsy: An unblended randomised controlled trial
    • A.G. Marson, A. Al-Kharusi, M. Alwaidh, R. Appleton, and G.A. Baker The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine or topiramate for treatment of partial epilepsy: an unblended randomised controlled trial Lancet 369 2007 1000 1015
    • (2007) Lancet , vol.369 , pp. 1000-1015
    • Marson, A.G.1    Al-Kharusi, A.2    Alwaidh, M.3    Appleton, R.4    Baker, G.A.5
  • 32
    • 0034598762 scopus 로고    scopus 로고
    • Early identification of refractory epilepsy
    • P. Kwan, and M.J. Brodie Early identification of refractory epilepsy N Engl Med 342 2000 314 319
    • (2000) N Engl Med , vol.342 , pp. 314-319
    • Kwan, P.1    Brodie, M.J.2
  • 33
    • 33644798598 scopus 로고    scopus 로고
    • Response to antiepileptic drug therapy: Winners and losers
    • M.J. Brodie Response to antiepileptic drug therapy: winners and losers Epilepsia 46 Suppl. 10 2006 31 32
    • (2006) Epilepsia , vol.46 , Issue.SUPPL. 10 , pp. 31-32
    • Brodie, M.J.1
  • 34
    • 77954625557 scopus 로고    scopus 로고
    • Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies
    • P. Kwan, A. Arzimanoglou, A.T. Berg, M.J. Brodie, and W.A. Hauser Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies Epilepsia 51 2010 1069 1077
    • (2010) Epilepsia , vol.51 , pp. 1069-1077
    • Kwan, P.1    Arzimanoglou, A.2    Berg, A.T.3    Brodie, M.J.4    Hauser, W.A.5
  • 35
    • 37849053121 scopus 로고    scopus 로고
    • Quantifying response to antiepileptic drugs: Effect of past treatment history
    • Y. Schiller, and Y. Najjar Quantifying response to antiepileptic drugs: effect of past treatment history Neurology 70 2008 54 65
    • (2008) Neurology , vol.70 , pp. 54-65
    • Schiller, Y.1    Najjar, Y.2
  • 36
    • 20544475805 scopus 로고    scopus 로고
    • Drug resistance in epilepsy: Putative neurobiologic and clinical mechanisms
    • T. Schmidt, and W. Lscher Drug resistance in epilepsy: putative neurobiologic and clinical mechanisms Epilepsia 46 2005 858 877
    • (2005) Epilepsia , vol.46 , pp. 858-877
    • Schmidt, T.1    Lscher, W.2
  • 37
    • 78649812045 scopus 로고    scopus 로고
    • Pharmacoresistance
    • Stefan H, Theodore WH editors. 3rd Series. Oxford, UK: Wiley-Blackwell, in press
    • Potschka H, Brodie MJ. Pharmacoresistance. In: Stefan H, Theodore WH editors. Handbook of clinical neurology, 3rd Series. Oxford, UK: Wiley-Blackwell, in press.
    • Handbook of Clinical Neurology
    • Potschka, H.1    Brodie, M.J.2
  • 38
    • 13244298981 scopus 로고    scopus 로고
    • Potential role of drug transporters in the pathogenesis of medically intractable epilepsy
    • P. Kwan, and M.J. Brodie Potential role of drug transporters in the pathogenesis of medically intractable epilepsy Epilepsia 46 2005 225 235
    • (2005) Epilepsia , vol.46 , pp. 225-235
    • Kwan, P.1    Brodie, M.J.2
  • 39
    • 33645053556 scopus 로고    scopus 로고
    • Serum antibodies in epilepsy and seizure-associated disorders
    • K. Mcnight, Y. Jiang, Y. Hart, A. Cavey, and B. Wroe Serum antibodies in epilepsy and seizure-associated disorders Neurology 65 2005 1730 1736
    • (2005) Neurology , vol.65 , pp. 1730-1736
    • McNight, K.1    Jiang, Y.2    Hart, Y.3    Cavey, A.4    Wroe, B.5
  • 40
    • 65249132928 scopus 로고    scopus 로고
    • Diagnostic value of N-methyl-d-aspartate receptor antibodies in women with new-onset epilepsy
    • P. Niehusmann, J. Dalmau, C. Rudlowski, A. Vincent, and C.E. Elger Diagnostic value of N-methyl-d-aspartate receptor antibodies in women with new-onset epilepsy Arch Neurol 66 2009 458 464
    • (2009) Arch Neurol , vol.66 , pp. 458-464
    • Niehusmann, P.1    Dalmau, J.2    Rudlowski, C.3    Vincent, A.4    Elger, C.E.5
  • 42
    • 72249087964 scopus 로고    scopus 로고
    • Mitochondria, oxidative stress and temporal lobe epilepsy
    • S. Waldbaum, and M. Patel Mitochondria, oxidative stress and temporal lobe epilepsy Epilepsy Res 88 2010 23 45
    • (2010) Epilepsy Res , vol.88 , pp. 23-45
    • Waldbaum, S.1    Patel, M.2
  • 43
    • 68149174964 scopus 로고    scopus 로고
    • Excitatory effects of gap junction blockers on cerebral cortex seizure-like activity in rats and mice
    • L.J. Voss, G. Jacobson, J.W. Sleigh, A. Steyn-Ross, and M. Steyn-Ross Excitatory effects of gap junction blockers on cerebral cortex seizure-like activity in rats and mice Epilepsia 50 2009 1971 1978
    • (2009) Epilepsia , vol.50 , pp. 1971-1978
    • Voss, L.J.1    Jacobson, G.2    Sleigh, J.W.3    Steyn-Ross, A.4    Steyn-Ross, M.5
  • 44
    • 0030970698 scopus 로고    scopus 로고
    • Reappraisal of polytherapy in epilepsy: A critical review of drug load and adverse effects
    • C.L. Deckers, Y.A. Hekster, P.F. Keyser, H. Meinardi, and W.O. Renier Reappraisal of polytherapy in epilepsy: a critical review of drug load and adverse effects Epilepsia 38 1997 570 575
    • (1997) Epilepsia , vol.38 , pp. 570-575
    • Deckers, C.L.1    Hekster, Y.A.2    Keyser, P.F.3    Meinardi, H.4    Renier, W.O.5
  • 45
    • 0033760422 scopus 로고    scopus 로고
    • Epilepsy after the first drug fails: Substitution or add-on?
    • P. Kwan, and M.J. Brodie Epilepsy after the first drug fails: substitution or add-on? Seizure 9 2000 464 468
    • (2000) Seizure , vol.9 , pp. 464-468
    • Kwan, P.1    Brodie, M.J.2
  • 46
    • 0030975686 scopus 로고    scopus 로고
    • Lamotrigine substitution study: Evidence for synergism with sodium valproate?
    • The 105 study group
    • M.J. Brodie, Yeun AWC The 105 study group Lamotrigine substitution study: evidence for synergism with sodium valproate? Epilepsy Res 26 1997 423 432
    • (1997) Epilepsy Res , vol.26 , pp. 423-432
    • Brodie, M.J.1    Yeun, A.W.C.2
  • 47
    • 0032799794 scopus 로고    scopus 로고
    • The efficacy of valproate-lamotrigine comedication in refractory complex partial seizures: Evidence for a pharmacodynamic interaction
    • F. Pisani, G. Otero, M.F. Russo, R. Di Perri, and E. Perucca The efficacy of valproate-lamotrigine comedication in refractory complex partial seizures: evidence for a pharmacodynamic interaction Epilepsia 40 1999 1141 1146
    • (1999) Epilepsia , vol.40 , pp. 1141-1146
    • Pisani, F.1    Otero, G.2    Russo, M.F.3    Di Perri, R.4    Perucca, E.5
  • 50
    • 0028304171 scopus 로고
    • Synergism with GABA-ergic drugs in refractory epilepsy
    • J.P. Leach, and M.J. Brodie Synergism with GABA-ergic drugs in refractory epilepsy Lancet 343 1994 1650
    • (1994) Lancet , vol.343 , pp. 1650
    • Leach, J.P.1    Brodie, M.J.2
  • 51
    • 0032495660 scopus 로고    scopus 로고
    • Lamotrigine and topiramate may be a useful combination
    • L.J. Stephen, G.J. Sills, and M.J. Brodie Lamotrigine and topiramate may be a useful combination Lancet 351 1998 958 959
    • (1998) Lancet , vol.351 , pp. 958-959
    • Stephen, L.J.1    Sills, G.J.2    Brodie, M.J.3
  • 53
    • 36148983791 scopus 로고    scopus 로고
    • Likelihood of seizure remission in adult population with refractory epilepsy
    • B.C. Callachan, K. Anand, D. Hesdorffer, W.A. Hauser, and J.A. French Likelihood of seizure remission in adult population with refractory epilepsy Ann Neurol 62 2007 382 389
    • (2007) Ann Neurol , vol.62 , pp. 382-389
    • Callachan, B.C.1    Anand, K.2    Hesdorffer, D.3    Hauser, W.A.4    French, J.A.5
  • 54
    • 36148981106 scopus 로고    scopus 로고
    • Results of treatment changes in patients with apparently drug-resistance chronic epilepsy
    • A.L. Luciano, and S.D. Shorvon Results of treatment changes in patients with apparently drug-resistance chronic epilepsy Annal Neurol 62 2007 375 381
    • (2007) Annal Neurol , vol.62 , pp. 375-381
    • Luciano, A.L.1    Shorvon, S.D.2
  • 55
    • 76249085581 scopus 로고    scopus 로고
    • Placebo-corrected efficacy of modern antiepileptic drugs and refractory epilepsy: Systematic review and metaanalysis
    • S. Beyenburg, K. Stavern, and D. Schmidt Placebo-corrected efficacy of modern antiepileptic drugs and refractory epilepsy: systematic review and metaanalysis Epilepsia 51 2010 7 26
    • (2010) Epilepsia , vol.51 , pp. 7-26
    • Beyenburg, S.1    Stavern, K.2    Schmidt, D.3
  • 56
    • 34447305538 scopus 로고    scopus 로고
    • Seizure-free outcome in randomized add-on trials of new antiepileptic drugs
    • D.M. Gazzola, L.J. Baller, and J.A. French Seizure-free outcome in randomized add-on trials of new antiepileptic drugs Epilepsia 48 2007 1303 1307
    • (2007) Epilepsia , vol.48 , pp. 1303-1307
    • Gazzola, D.M.1    Baller, L.J.2    French, J.A.3
  • 57
    • 67249111268 scopus 로고    scopus 로고
    • Remission of epilepsy after two drug failures in children: A prospective study
    • A.T. Berg, S.R. Levy, F.M. Testa, and R. D'souza Remission of epilepsy after two drug failures in children: a prospective study Ann Neurol 65 2009 510 519
    • (2009) Ann Neurol , vol.65 , pp. 510-519
    • Berg, A.T.1    Levy, S.R.2    Testa, F.M.3    D'Souza, R.4
  • 58
    • 77954462067 scopus 로고    scopus 로고
    • Course and outcome of childhood epilepsy: A 15 year follow-up of the Dutch Study of Epilepsy in Childhood
    • A. Geerts, W.F. Arts, H. Stroink, E. Peeters, and O. Brouwer Course and outcome of childhood epilepsy: a 15 year follow-up of the Dutch Study of Epilepsy in Childhood Epilepsia 2010 1189 1197
    • (2010) Epilepsia , pp. 1189-1197
    • Geerts, A.1    Arts, W.F.2    Stroink, H.3    Peeters, E.4    Brouwer, O.5
  • 59
    • 33645305420 scopus 로고    scopus 로고
    • Diagnosing refractory epilepsy: Response to sequential treatment schedules
    • R. Mohanraj, and M.J. Brodie Diagnosing refractory epilepsy: response to sequential treatment schedules Eur J Neurol 13 2006 277 282
    • (2006) Eur J Neurol , vol.13 , pp. 277-282
    • Mohanraj, R.1    Brodie, M.J.2
  • 60
    • 72049116140 scopus 로고    scopus 로고
    • Improved outcomes in newly diagnosed epilepsy
    • M.J. Brodie, G. Bamagous, and P. Kwan Improved outcomes in newly diagnosed epilepsy Epilepsia 50 Suppl. 11 2009 411 412
    • (2009) Epilepsia , vol.50 , Issue.SUPPL. 11 , pp. 411-412
    • Brodie, M.J.1    Bamagous, G.2    Kwan, P.3
  • 61
    • 77954498319 scopus 로고    scopus 로고
    • Therapeutic approaches to epileptogenesis - Hope on the horizon
    • A. Pitkänen Therapeutic approaches to epileptogenesis - Hope on the horizon Epilepsia S1 Suppl. 3 2010 2 17
    • (2010) Epilepsia , vol.1 , Issue.SUPPL. 3 , pp. 2-17
    • Pitkänen, A.1
  • 62
    • 65249131854 scopus 로고    scopus 로고
    • Emerging concepts in the pathogenesis of epilepsy and epileptogenesis
    • M.A. Dichter Emerging concepts in the pathogenesis of epilepsy and epileptogenesis Arch Neurol 66 2009 443 447
    • (2009) Arch Neurol , vol.66 , pp. 443-447
    • Dichter, M.A.1
  • 63
    • 77950857874 scopus 로고    scopus 로고
    • Revised terminology and concepts for organisation of the epilepsies: Report of the Ilae commission and classification and terminology
    • doi:10.1111/j.1528-1167.2010.02522.x inpress
    • Berg AT, Berkovic SF, Brodie MJ, Buchhalter J, Cross JH et al. Revised terminology and concepts for organisation of the epilepsies: report of the Ilae commission and classification and terminology. Epilepsia doi:10.1111/j.1528- 1167.2010.02522.x, in press.
    • Epilepsia
    • Berg, A.T.1    Berkovic, S.F.2    Brodie, M.J.3    Buchhalter, J.4    Cross, J.H.5
  • 64
    • 77951547487 scopus 로고    scopus 로고
    • The personal genome - The future of personalised medicine
    • N.J. Samani, M. Tomaszewski, and H. Schunkert The personal genome - the future of personalised medicine Lancet 375 2010 1497 1498
    • (2010) Lancet , vol.375 , pp. 1497-1498
    • Samani, N.J.1    Tomaszewski, M.2    Schunkert, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.