ANTIEPILEPTIC DRUGS | Preclinical Drug Development in Epilepsy

Encyclopedia of Basic Epilepsy Research

Volumn , Issue , 2009, Pages 97-103

  Sills, G J ^a   Brodie, M J ^b  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Drug development; Drug discovery; Drug resistance; Efficacy; Epileptogenesis; Experimental seizure models; Mechanism of action; Toxicity

Indexed keywords

EID: 85050636589     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012373961-2.00032-1     Document Type: Chapter

References (11)

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2. G.L. Holmes (2007) Animal model studies application to human patients. Neurology 69(supplement 3), S28-S32.
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8. M. Smith, K.S. Wilcox and H.S. White (2007) Discovery of antiepileptic drugs. Neurotherapeutics 4 12-17.
9. J.P. Stables, E.H. Bertram, H.S. White, et al. (2002) Models for epilepsy and epileptogenesis: Report from the NIH Workshop, Bethesda, Maryland. Epilepsia 43 1410-1420.
10. H.S. White (2003) Preclinical development of antiepileptic drugs: past, present, and future directions. Epilepsia 44(supplement 7), 2-8.
11. H.S. White, J.H. Woodhead, K.S. Wilcox, et al. (2002) Discovery and preclinical development of antiepileptic drugs. R.H. Levy, R.H. Mattson, B.S. Meldrum, E. Perucca (Eds) Antiepileptic Drugs 5th edn. Philadelphia: Lippincott, Williams & Wilkins 36-48.