Remission of epilepsy after two drug failures in children: A prospective study

Annals of Neurology

Volumn 65, Issue 5, 2009, Pages 510-519

  Berg, Anne T ^a,c   Levy, Susan R ^b   Testa, Francine M ^b   D'Souza, Ramona ^a  

^a NORTHERN ILLINOIS UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NIU ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; CARBAMAZEPINE; CLONAZEPAM; CLORAZEPATE; CORTICOTROPIN; DIAZEPAM; ETHOSUXIMIDE; ETHOTOIN; ETIRACETAM; FELBAMATE; GABAPENTIN; LAMOTRIGINE; LORAZEPAM; MESUXIMIDE; NITRAZEPAM; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PREDNISONE; PREGABALIN; PRIMIDONE; TIAGABINE; TOPIRAMATE; VALPROIC ACID; VIGABATRIN; ZONISAMIDE;

ADOLESCENT; ARTICLE; CHILD; CONTROLLED STUDY; DRUG TREATMENT FAILURE; EPILEPSY; FOCAL EPILEPSY; FOLLOW UP; GENERALIZED EPILEPSY; HUMAN; INFANT; MAJOR CLINICAL STUDY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROGNOSIS; RELAPSE; REMISSION; SCHOOL CHILD;

ADOLESCENT; ANTICONVULSANTS; CHI-SQUARE DISTRIBUTION; CHILD; CHILD, PRESCHOOL; DRUG THERAPY, COMBINATION; EPILEPSY; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; INFANT, NEWBORN; MALE; PREDICTIVE VALUE OF TESTS; PROBABILITY; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RECURRENCE; RETROSPECTIVE STUDIES; TIME FACTORS; TREATMENT FAILURE;

EID: 67249111268     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.21642     Document Type: Article

References (27)

1. Dlugos D, Sammel M, Strom B, Farrar J. Response to first drug trial predicts outcome in childhood temporal lobe epilepsy. Neurology 2001;57:2259-2264. (Pubitemid 34016461)
2. Camfield P, Camfield C. Nova Scotia pediatric epilepsy study. In: Jallon P, Berg A, Dulac O, Hauser A, eds. Prognosis of epilepsies. Montrouge, France: John Libbey, Eurotext, 2003: 113-126.
3. Arts WFM, Brouwer OF, Peters ACB, et al. Course and prognosis of childhood epilepsy: 5-year follow-up of the Dutch study of epilepsy in childhood. Brain 2004;127:1774-1784. (Pubitemid 39061554)
4. Berg AT, Vickrey BG, Testa FM, et al. How long does it take epilepsy to become intractable? A prospective investigation. Ann Neurol 2006;60:73-79.
5. Spooner CG, Berkovic SF, Mitchell LA, et al. New onset temporal lobe epilepsy in children: lesion on MRI predicts poor seizure outcome. Neurology 2006;67:2147-2153. (Pubitemid 46035466)
6. Engel J. The goal of epilepsy therapy: no seizures, no side effects, as soon as possible. CNS Spectrums 2004;9:95-97.
7. Mathern GW, Pretorius JK, Babb TL. Influence of the type of initial precipitating injury and at what age it occurs on course and outcome in patients with temporal lobe seizures. J Neurosurg 1995;82:220-227.
8. Cross JH, Jaykar P, Nordli D, et al. Propose criteria for referral and evaluation of children for epilepsy surgery: recommendations of the Subcomission for Pediatric Epilepsy Surgery. Epilepsia 2006;47:953-959. (Pubitemid 43801505)
9. Weiner HL, Carlson C, Ridgway EB, et al. Epilepsy surgery in young children with tuberous sclerosis: results of a novel approach. Pediatrics 2006;117:1494-1502. (Pubitemid 46071375)
10. Luciano AL, Shorvon SD. Results of treatment changes in patients with apparently drug-resistant chronic epilepsy. Ann Neurol 2007;62:375-381. (Pubitemid 350105951)
11. Callaghan BC, Anand K, Hesdorffer D, et al. Likelihood of seizure remission in an adult population with refractory epilepsy. Ann Neurol 2007;62:382-389. (Pubitemid 350105952)
12. Huttenlocher PR, Hapke RJ. A follow-up study of intractable seizures in childhood. Ann Neurol 1990;28:699-705. (Pubitemid 20373906)
13. Takenaka J, Aso K, Watanabe K, et al. Transient remission in intractable localization-related epilepsy. Pediatr Neurol 2000; 23:328-331. (Pubitemid 30799392)
14. Berg AT, Levy SR, Novotny EJ, Shinnar S. Predictors of intractable epilepsy in childhood: a case-control study. Epilepsia 1996;37:24-30. (Pubitemid 26021572)
15. Berg AT, Shinnar S, Levy SR, et al. Early development of intractable epilepsy in children: a prospective study. Neurology 2001;56:1445-1452. (Pubitemid 32532255)
16. Berg AT, Shinnar S, Levy SR, Testa FM. Newly diagnosed epilepsy in children: presentation at diagnosis. Epilepsia 1999;40: 445-452. (Pubitemid 29164856)
17. Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 1989;30: 389-399.
18. Roger J, Bureau M, Dravet C, et al. Epileptic syndromes in infancy, childhood, and adolescence. 2nd ed. London: John Libbey, 1992. 19
19. Schiller Y, Najjar Y. Quantifying the response to antiepileptic drugs: effect of past treatment history. Neurology 2008;70: 54-65.
20. Berg AT, Langfitt J, Shinnar S, et al. How long does it take for partial epilepsy to become intractable? Neurology 2003;60: 186-190.
21. Sperling MR. The consequences of uncontrolled epilepsy. CNS Spectrums 2004;9:106-109. (Pubitemid 38405562)
22. Wheless JW, Clarke DF, Arzimanoglou A, Carpenter D. Treatment of pediatric epilepsy: European expert opinion, 2007. Epileptic Disord 2007;9:353-412. (Pubitemid 351147653)
23. Wheless JW, Clarke DF, Carpenter D. Treatment of pediatric epilepsy: expert opinion, 2005. J Child Neurol 2005;20:S1-S56. (Pubitemid 43230877)
24. Berg AT. Our work is still cut out for us. . .. Epileptic Disord 2008;10:68-69.
25. French JA. Refractory epilepsy: one size does not fit all. Epilepsy Curr 2006;6:177-180.
26. Arzimanoglou A, Ryvlin P. Toward a clinically meaningful definition of drug resistance. In: Kahane P, Berg A, Loscher W, et al., eds. Drug resistant epilepsies. Montrouge, France: John Libbey Eurotext, 2008:1-6.
27. Berg AT. The risks, correlates, and temporal patterns of intractable epilepsy. In: Kahane P, Berg A, Loscher W, et al, eds. Drug resistant epilepsies. Montrouge, France: John Libbey Eurotext, 2008:7-16.