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Volumn 10, Issue 6, 2010, Pages 462-470

Immunotherapy of malignant gliomas using autologous and allogeneic tissue cells

Author keywords

Allogeneic; Astrocytoma; Biotherapy; Brain tumor; CTL; Glioma; Immunization; Immunotherapy

Indexed keywords

ALPHA INTERFERON; BCG VACCINE; CDX110; COTARA; CPG OLIGODEOXYNUCLEOTIDE; DCVAX; DENDRITIC CELL VACCINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEAT SHOCK PROTEIN 70; INTERLEUKIN 2; INTERLEUKIN 4; IODINE 131; RESIQUIMOD; TEMOZOLOMIDE; TUMOR ANTIGEN; TUMOR VACCINE; UNCLASSIFIED DRUG;

EID: 78649837190     PISSN: 18715206     EISSN: None     Source Type: Journal    
DOI: 10.2174/1871520611009060462     Document Type: Article
Times cited : (19)

References (101)
  • 1
    • 59349103735 scopus 로고    scopus 로고
    • Recent advances incancer vaccines: An overview
    • Itoh, K.; Yamada, A.; Mine, T.; Noguchi, M. Recent advances incancer vaccines: an overview. Jpn. J. Clin. Oncol., 2009, 39 (2), 73-80.
    • (2009) Jpn. J. Clin. Oncol. , vol.39 , Issue.2 , pp. 73-80
    • Itoh, K.1    Yamada, A.2    Mine, T.3    Noguchi, M.4
  • 4
    • 33847052535 scopus 로고    scopus 로고
    • Mechanisms of malignant gliomaimmune resistance and sources of immunosuppression
    • Gomez, G. G.; Kruse, C. A. Mechanisms of malignant gliomaimmune resistance and sources of immunosuppression. Gene Ther.Mol. Biol., 2006, 10 (A), 133-146.
    • (2006) Gene Ther.Mol. Biol. , vol.10 , Issue.A , pp. 133-146
    • Gomez, G.G.1    Kruse, C.A.2
  • 5
    • 0033398454 scopus 로고    scopus 로고
    • Immune defects observed in patients with primary malignant braintumors
    • Dix, A. R.; Brooks, W. H.; Roszman, T. L.; Morford, L. A.Immune defects observed in patients with primary malignant braintumors. J. Neuroimmunol., 1999, 100 (1-2), 216-232.
    • (1999) J. Neuroimmunol. , vol.100 , Issue.1-2 , pp. 216-232
    • Dix, A.R.1    Brooks, W.H.2    Roszman, T.L.3    Morford, L.A.4
  • 6
    • 33748481603 scopus 로고    scopus 로고
    • An increase inCD4+CD25+FOXP3+ regulatory T cells in tumor-infiltratinglymphocytes of human glioblastoma multiforme
    • El Andaloussi, A.; Lesniak, M. S. An increase inCD4+CD25+FOXP3+ regulatory T cells in tumor-infiltratinglymphocytes of human glioblastoma multiforme. Neuro. Oncol., 2006, 8 (3), 234-243.
    • (2006) Neuro. Oncol. , vol.8 , Issue.3 , pp. 234-243
    • El Andaloussi, A.1    Lesniak, M.S.2
  • 9
    • 23044479028 scopus 로고    scopus 로고
    • Dendritic cell vaccination inglioblastoma patients induces systemic and intracranial T-cellresponses modulated by the local central nervous system tumormicroenvironment
    • Liau, L. M.; Prins, R. M.; Kiertscher, S. M.; Odesa, S. K.; Kremen, T. J.; Giovannone, A. J.; Lin, J. W.; Chute, D. J.; Mischel, P. S.; Cloughesy, T. F.; Roth, M. D. Dendritic cell vaccination inglioblastoma patients induces systemic and intracranial T-cellresponses modulated by the local central nervous system tumormicroenvironment. Clin. Cancer Res., 2005, 11 (15), 5515-5525.
    • (2005) Clin. Cancer Res. , vol.11 , Issue.15 , pp. 5515-5525
    • Liau, L.M.1    Prins, R.M.2    Kiertscher, S.M.3    Odesa, S.K.4    Kremen, T.J.5    Giovannone, A.J.6    Lin, J.W.7    Chute, D.J.8    Mischel, P.S.9    Cloughesy, T.F.10    Roth, M.D.11
  • 10
    • 33747195058 scopus 로고    scopus 로고
    • Trends inbrain cancer incidence and survival in the United States: Surveillance, Epidemiology, and End Results Program, 1973 to2001
    • Deorah, S.; Lynch, C. F.; Sibenaller, Z. A.; Ryken, T. C. Trends inbrain cancer incidence and survival in the United States: Surveillance, Epidemiology, and End Results Program, 1973 to2001. Neurosurg. Focus, 2006, 20 (4), E1.
    • (2006) Neurosurg. Focus , vol.20 , Issue.4
    • Deorah, S.1    Lynch, C.F.2    Sibenaller, Z.A.3    Ryken, T.C.4
  • 13
    • 0026602628 scopus 로고
    • Coley's toxins in perspective
    • Starnes, C. O. Coley's toxins in perspective. Nature, 1992, 357(6373), 11-12.
    • (1992) Nature , vol.357 , Issue.6373 , pp. 11-12
    • Starnes, C.O.1
  • 14
    • 0026060863 scopus 로고
    • The treatment of malignant tumors by repeatedinoculations of erysipelas. With a report of ten original cases. 1893
    • Coley, W. B. The treatment of malignant tumors by repeatedinoculations of erysipelas. With a report of ten original cases. 1893.Clin. Orthop. Relat. Res., 1991, (262), 3-11.
    • (1991) Clin. Orthop. Relat. Res. , Issue.262 , pp. 3-11
    • Coley, W.B.1
  • 15
    • 78649881669 scopus 로고    scopus 로고
    • A commotion in the Blood: Life, death and the immunesystem
    • Hall, S. S. A commotion in the Blood: Life, death and the immunesystem. Holt Paperbacks 1997.
    • (1997) Holt Paperbacks
    • Hall, S.S.1
  • 16
    • 0021199765 scopus 로고
    • Immunotherapy of patientswith glioma: Fact, fancy, and future
    • Mahaley, M. S., Jr.; Gillespie, G. Y. Immunotherapy of patientswith glioma: fact, fancy, and future. Prog. Exp. Tumor Res., 1984, 28, 118-135.
    • (1984) Prog. Exp. Tumor Res. , vol.28 , pp. 118-135
    • Mahaley Jr., M.S.1    Gillespie, G.Y.2
  • 18
    • 0014760489 scopus 로고
    • Active immunotherapy of cerebral tumor.20 cases
    • Trouillas, P.; Lapras, C. Active immunotherapy of cerebral tumor.20 cases. Neurochirurgie, 1970, 16 (2), 143-170.
    • (1970) Neurochirurgie , vol.16 , Issue.2 , pp. 143-170
    • Trouillas, P.1    Lapras, C.2
  • 19
    • 0038713591 scopus 로고    scopus 로고
    • Human alloreactiveCTL interactions with gliomas and with those having upregulatedHLA expression from exogenous IFN-gamma or IFN-gamma genemodification
    • Read, S. B.; Kulprathipanja, N. V.; Gomez, G. G.; Paul, D. B.; Winston, K. R.; Robbins, J. M.; Kruse, C. A. Human alloreactiveCTL interactions with gliomas and with those having upregulatedHLA expression from exogenous IFN-gamma or IFN-gamma genemodification. J Interferon Cytokine Res., 2003, 23 (7), 379-393.
    • (2003) J Interferon Cytokine Res. , vol.23 , Issue.7 , pp. 379-393
    • Read, S.B.1    Kulprathipanja, N.V.2    Gomez, G.G.3    Paul, D.B.4    Winston, K.R.5    Robbins, J.M.6    Kruse, C.A.7
  • 20
    • 0034118217 scopus 로고    scopus 로고
    • Glioma immunology and immunotherapy
    • discussion791-772
    • Parney, I. F.; Hao, C.; Petruk, K. C. Glioma immunology and immunotherapy. Neurosurgery, 2000, 46 (4), 778-791; discussion791-772.
    • (2000) Neurosurgery , vol.46 , Issue.4 , pp. 778-791
    • Parney, I.F.1    Hao, C.2    Petruk, K.C.3
  • 22
    • 0018180952 scopus 로고
    • Clinicalstudies of intrathecal autologous lymphocyte infusions in patientswith malignant glioma: A toxicity study
    • Neuwelt, E. A.; Clark, K.; Kirkpatrick, J. B.; Toben, H. Clinicalstudies of intrathecal autologous lymphocyte infusions in patientswith malignant glioma: a toxicity study. Ann. Neurol., 1978, 4 (4), 307-312.
    • (1978) Ann. Neurol. , vol.4 , Issue.4 , pp. 307-312
    • Neuwelt, E.A.1    Clark, K.2    Kirkpatrick, J.B.3    Toben, H.4
  • 24
    • 0035352398 scopus 로고    scopus 로고
    • Immunologic approaches to therapy forbrain tumors
    • Paul, D. B.; Kruse, C. A. Immunologic approaches to therapy forbrain tumors. Curr. Neurol. Neurosci. Rep., 2001, 1 (3), 238-244.
    • (2001) Curr. Neurol. Neurosci. Rep. , vol.1 , Issue.3 , pp. 238-244
    • Paul, D.B.1    Kruse, C.A.2
  • 26
    • 0041833713 scopus 로고    scopus 로고
    • Effects of local injection of ex vivoexpanded autologous tumor-specific T lymphocytes in cases withrecurrent malignant gliomas
    • Tsuboi, K.; Saijo, K.; Ishikawa, E.; Tsurushima, H.; Takano, S.; Morishita, Y.; Ohno, T. Effects of local injection of ex vivoexpanded autologous tumor-specific T lymphocytes in cases withrecurrent malignant gliomas. Clin. Cancer Res., 2003, 9 (9), 3294-3302.
    • (2003) Clin. Cancer Res. , vol.9 , Issue.9 , pp. 3294-3302
    • Tsuboi, K.1    Saijo, K.2    Ishikawa, E.3    Tsurushima, H.4    Takano, S.5    Morishita, Y.6    Ohno, T.7
  • 27
    • 51349095229 scopus 로고    scopus 로고
    • Overcoming obstacles to the effectiveimmunotherapy of human cancer
    • Rosenberg, S. A. Overcoming obstacles to the effectiveimmunotherapy of human cancer. Proc. Natl. Acad. Sci. USA, 2008, 105 (35), 12643-12644.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , Issue.35 , pp. 12643-12644
    • Rosenberg, S.A.1
  • 28
    • 0020507444 scopus 로고
    • Immunobiology of primary intracranial tumors. Part 7: Activeimmunization of patients with anaplastic human glioma cells: Apilot study
    • Mahaley, M. S., Jr.; Bigner, D. D.; Dudka, L. F.; Wilds, P. R.; Williams, D. H.; Bouldin, T. W.; Whitaker, J. N.; Bynum, J. M.Immunobiology of primary intracranial tumors. Part 7: Activeimmunization of patients with anaplastic human glioma cells: apilot study. J. Neurosurg., 1983, 59 (2), 201-207.
    • (1983) J. Neurosurg. , vol.59 , Issue.2 , pp. 201-207
    • Mahaley Jr., M.S.1    Bigner, D.D.2    Dudka, L.F.3    Wilds, P.R.4    Williams, D.H.5    Bouldin, T.W.6    Whitaker, J.N.7    Bynum, J.M.8
  • 31
    • 42349107959 scopus 로고    scopus 로고
    • Tumor antigenprecursor protein profiles of adult and pediatric brain tumorsidentify potential targets for immunotherapy
    • Zhang, J. G.; Kruse, C. A.; Driggers, L.; Hoa, N.; Wisoff, J.; Allen, J. C.; Zagzag, D.; Newcomb, E. W.; Jadus, M. R. Tumor antigenprecursor protein profiles of adult and pediatric brain tumorsidentify potential targets for immunotherapy. J. Neurooncol., 2008, 88 (1), 65-76.
    • (2008) J. Neurooncol. , vol.88 , Issue.1 , pp. 65-76
    • Zhang, J.G.1    Kruse, C.A.2    Driggers, L.3    Hoa, N.4    Wisoff, J.5    Allen, J.C.6    Zagzag, D.7    Newcomb, E.W.8    Jadus, M.R.9
  • 34
    • 77951599543 scopus 로고    scopus 로고
    • Targeting brain cancer: Advances in themolecular pathology of malignant glioma and medulloblastoma
    • Huse, J. T.; Holland, E. C. Targeting brain cancer: advances in themolecular pathology of malignant glioma and medulloblastoma.Nat. Rev. Cancer, 2010, 10 (5), 319-331.
    • (2010) Nat. Rev. Cancer , vol.10 , Issue.5 , pp. 319-331
    • Huse, J.T.1    Holland, E.C.2
  • 35
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensivegenomic characterization defines human glioblastoma genes and core pathways
    • Cancer Genome Atlas Research Networks
    • Cancer Genome Atlas Research Networks. Comprehensivegenomic characterization defines human glioblastoma genes and core pathways. Nature, 2008, 455 (7216), 1061-1068.
    • (2008) Nature , vol.455 , Issue.7216 , pp. 1061-1068
  • 36
    • 0030956966 scopus 로고    scopus 로고
    • Molecular detection of tumor-associated antigens shared by human cutaneous melanomasand gliomas
    • Chi, D. D.; Merchant, R. E.; Rand, R.; Conrad, A. J.; Garrison, D.; Turner, R.; Morton, D. L.; Hoon, D. S. Molecular detection of tumor-associated antigens shared by human cutaneous melanomasand gliomas. Am. J. Pathol., 1997, 150 (6), 2143-2152.
    • (1997) Am. J. Pathol. , vol.150 , Issue.6 , pp. 2143-2152
    • Chi, D.D.1    Merchant, R.E.2    Rand, R.3    Conrad, A.J.4    Garrison, D.5    Turner, R.6    Morton, D.L.7    Hoon, D.S.8
  • 38
    • 0034125081 scopus 로고    scopus 로고
    • Immunological concepts of vaccine adjuvantactivity
    • Schijns, V. E. Immunological concepts of vaccine adjuvantactivity. Curr. Opin. Immunol., 2000, 12 (4), 456-463.
    • (2000) Curr. Opin. Immunol. , vol.12 , Issue.4 , pp. 456-463
    • Schijns, V.E.1
  • 40
    • 0345865089 scopus 로고    scopus 로고
    • Dendritic cells: A journeyfrom laboratory to clinic
    • Cerundolo, V.; Hermans, I. F.; Salio, M. Dendritic cells: a journeyfrom laboratory to clinic. Nat. Immunol., 2004, 5 (1), 7-10.
    • (2004) Nat. Immunol. , vol.5 , Issue.1 , pp. 7-10
    • Cerundolo, V.1    Hermans, I.F.2    Salio, M.3
  • 44
    • 3142692559 scopus 로고    scopus 로고
    • Vaccination with tumor lysate-pulsed dendritic cells elicitsantigen-specific, cytotoxic T-cells in patients with malignantglioma
    • Yu, J. S.; Liu, G.; Ying, H.; Yong, W. H.; Black, K. L.; Wheeler, C. J. Vaccination with tumor lysate-pulsed dendritic cells elicitsantigen-specific, cytotoxic T-cells in patients with malignantglioma. Cancer Res., 2004, 64 (14), 4973-4979.
    • (2004) Cancer Res. , vol.64 , Issue.14 , pp. 4973-4979
    • Yu, J.S.1    Liu, G.2    Ying, H.3    Yong, W.H.4    Black, K.L.5    Wheeler, C.J.6
  • 45
    • 0043065333 scopus 로고    scopus 로고
    • Autologous glioma cell vaccine admixed withinterleukin-4 gene transfected fibroblasts in the treatment of recurrent glioblastoma: Preliminary observations in a patient with afavorable response to therapy
    • Okada, H.; Lieberman, F. S.; Edington, H. D.; Witham, T. F.; Wargo, M. J.; Cai, Q.; Elder, E. H.; Whiteside, T. L.; Schold, S. C., Jr.; Pollack, I. F. Autologous glioma cell vaccine admixed withinterleukin-4 gene transfected fibroblasts in the treatment of recurrent glioblastoma: preliminary observations in a patient with afavorable response to therapy. J. Neurooncol., 2003, 64 (1-2), 13-20.
    • (2003) J. Neurooncol. , vol.64 , Issue.1-2 , pp. 13-20
    • Okada, H.1    Lieberman, F.S.2    Edington, H.D.3    Witham, T.F.4    Wargo, M.J.5    Cai, Q.6    Elder, E.H.7    Whiteside, T.L.8    Schold Jr., S.C.9    Pollack, I.F.10
  • 46
    • 0029959095 scopus 로고    scopus 로고
    • Cure of established, intracerebral rat gliomas induced by therapeutic immunizationswith tumor cells and purified APC or adjuvant IFN-gammatreatment
    • Siesjo, P.; Visse, E.; Sjogren, H. O. Cure of established, intracerebral rat gliomas induced by therapeutic immunizationswith tumor cells and purified APC or adjuvant IFN-gammatreatment. J. Immunother. Emphasis Tumor Immunol., 1996, 19 (5), 334-345.
    • (1996) J. Immunother. Emphasis Tumor Immunol. , vol.19 , Issue.5 , pp. 334-345
    • Siesjo, P.1    Visse, E.2    Sjogren, H.O.3
  • 47
    • 36148980080 scopus 로고    scopus 로고
    • Vaccine immunopotentiators of thefuture
    • Schijns, V. E.; Degen, W. G. Vaccine immunopotentiators of thefuture. Clin. Pharmacol. Ther., 2007, 82 (6), 750-755.
    • (2007) Clin. Pharmacol. Ther. , vol.82 , Issue.6 , pp. 750-755
    • Schijns, V.E.1    Degen, W.G.2
  • 48
    • 33646261645 scopus 로고    scopus 로고
    • Adoptive transfer of type 1 CTLmediates effective anti-central nervous system tumor response: Critical roles of IFN-inducible protein-10
    • Nishimura, F.; Dusak, J. E.; Eguchi, J.; Zhu, X.; Gambotto, A.; Storkus, W. J.; Okada, H. Adoptive transfer of type 1 CTLmediates effective anti-central nervous system tumor response: critical roles of IFN-inducible protein-10. Cancer Res., 2006, 66(8), 4478-4487.
    • (2006) Cancer Res. , vol.66 , Issue.8 , pp. 4478-4487
    • Nishimura, F.1    Dusak, J.E.2    Eguchi, J.3    Zhu, X.4    Gambotto, A.5    Storkus, W.J.6    Okada, H.7
  • 49
    • 47749134507 scopus 로고    scopus 로고
    • Activation of NK cells by extracellularheat shock protein 70 through induction of NKG2D ligands ondendritic cells
    • Qiao, Y.; Liu, B.; Li, Z. Activation of NK cells by extracellularheat shock protein 70 through induction of NKG2D ligands ondendritic cells. Cancer Immunol., 2008, 8, 12.
    • (2008) Cancer Immunol. , vol.8 , pp. 12
    • Qiao, Y.1    Liu, B.2    Li, Z.3
  • 50
    • 34248172651 scopus 로고    scopus 로고
    • CD4+FoxP3+regulatory T cells gradually accumulate in gliomas during tumorgrowth and efficiently suppress antiglioma immune responses invivo
    • Grauer, O. M.; Nierkens, S.; Bennink, E.; Toonen, L. W.; Boon, L.; Wesseling, P.; Sutmuller, R. P.; Adema, G. J. CD4+FoxP3+regulatory T cells gradually accumulate in gliomas during tumorgrowth and efficiently suppress antiglioma immune responses invivo. Int. J. Cancer, 2007, 121 (1), 95-105.
    • (2007) Int. J. Cancer , vol.121 , Issue.1 , pp. 95-105
    • Grauer, O.M.1    Nierkens, S.2    Bennink, E.3    Toonen, L.W.4    Boon, L.5    Wesseling, P.6    Sutmuller, R.P.7    Adema, G.J.8
  • 54
    • 0032529466 scopus 로고    scopus 로고
    • CD8+ T cells infiltrated within cancer cell nests as aprognostic factor in human colorectal cancer
    • Naito, Y.; Saito, K.; Shiiba, K.; Ohuchi, A.; Saigenji, K.; Nagura, H.; Ohtani, H. CD8+ T cells infiltrated within cancer cell nests as aprognostic factor in human colorectal cancer. Cancer Res., 1998, 58 (16), 3491-3494.
    • (1998) Cancer Res. , vol.58 , Issue.16 , pp. 3491-3494
    • Naito, Y.1    Saito, K.2    Shiiba, K.3    Ohuchi, A.4    Saigenji, K.5    Nagura, H.6    Ohtani, H.7
  • 56
    • 0035394233 scopus 로고    scopus 로고
    • Proliferativeactivity of intratumoral CD8(+) T-lymphocytes as a prognosticfactor in human renal cell carcinoma: Clinicopathologicdemonstration of antitumor immunity
    • Nakano, O.; Sato, M.; Naito, Y.; Suzuki, K.; Orikasa, S.; Aizawa, M.; Suzuki, Y.; Shintaku, I.; Nagura, H.; Ohtani, H. Proliferativeactivity of intratumoral CD8(+) T-lymphocytes as a prognosticfactor in human renal cell carcinoma: clinicopathologicdemonstration of antitumor immunity. Cancer Res., 2001, 61 (13), 5132-5136.
    • (2001) Cancer Res. , vol.61 , Issue.13 , pp. 5132-5136
    • Nakano, O.1    Sato, M.2    Naito, Y.3    Suzuki, K.4    Orikasa, S.5    Aizawa, M.6    Suzuki, Y.7    Shintaku, I.8    Nagura, H.9    Ohtani, H.10
  • 57
    • 0028032388 scopus 로고
    • Histologicalgrade, perineural infiltration, tumour-infiltrating lymphocytes and apoptosis as determinants of long-term prognosis in prostaticadenocarcinoma
    • Vesalainen, S.; Lipponen, P.; Talja, M.; Syrjanen, K. Histologicalgrade, perineural infiltration, tumour-infiltrating lymphocytes and apoptosis as determinants of long-term prognosis in prostaticadenocarcinoma. Eur. J. Cancer, 1994, 30A (12), 1797-1803.
    • (1994) Eur. J. Cancer , vol.30 A , Issue.12 , pp. 1797-1803
    • Vesalainen, S.1    Lipponen, P.2    Talja, M.3    Syrjanen, K.4
  • 58
    • 0030659077 scopus 로고    scopus 로고
    • Study of tumorinfiltrating lymphocytes and transforming growth factor-beta asprognostic factors in breast carcinoma
    • Marrogi, A. J.; Munshi, A.; Merogi, A. J.; Ohadike, Y.; El-Habashi, A.; Marrogi, O. L.; Freeman, S. M. Study of tumorinfiltrating lymphocytes and transforming growth factor-beta asprognostic factors in breast carcinoma. Int. J. Cancer, 1997, 74 (5), 492-501.
    • (1997) Int. J. Cancer , vol.74 , Issue.5 , pp. 492-501
    • Marrogi, A.J.1    Munshi, A.2    Merogi, A.J.3    Ohadike, Y.4    El-Habashi, A.5    Marrogi, O.L.6    Freeman, S.M.7
  • 59
    • 61749098024 scopus 로고    scopus 로고
    • Immunotherapeutic applications of CpGoligodeoxynucleotide TLR9 agonists
    • Vollmer, J.; Krieg, A. M. Immunotherapeutic applications of CpGoligodeoxynucleotide TLR9 agonists. Adv. Drug Deliv. Rev., 2009, 61 (3), 195-204.
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , Issue.3 , pp. 195-204
    • Vollmer, J.1    Krieg, A.M.2
  • 61
    • 37848999304 scopus 로고    scopus 로고
    • TLR7 and TLR8 as targets in cancertherapy
    • Schon, M. P.; Schon, M. TLR7 and TLR8 as targets in cancertherapy. Oncogene, 2008, 27 (2), 190-199.
    • (2008) Oncogene , vol.27 , Issue.2 , pp. 190-199
    • Schon, M.P.1    Schon, M.2
  • 62
    • 77949888505 scopus 로고    scopus 로고
    • Clinical Update: Treatment of glioblastomamultiforme with radiolabeled antibodies that target tumor necrosis
    • Jensen, R.; Shan, J.; Freimark, B.; Harris, D.; King, S.; Lai, J.; Parseghian, M. Clinical Update: treatment of glioblastomamultiforme with radiolabeled antibodies that target tumor necrosis.Curr. Cancer Ther. Rev., 2010, 6, 13-18.
    • (2010) Curr. Cancer Ther. Rev. , vol.6 , pp. 13-18
    • Jensen, R.1    Shan, J.2    Freimark, B.3    Harris, D.4    King, S.5    Lai, J.6    Parseghian, M.7
  • 63
    • 0037829431 scopus 로고    scopus 로고
    • LEC/chTNT-3 fusionprotein for the immunotherapy of experimental solid tumors
    • Li, J.; Hu, P.; Khawli, L. A.; Epstein, A. L. LEC/chTNT-3 fusionprotein for the immunotherapy of experimental solid tumors. J.Immunother., 2003, 26 (4), 320-331.
    • (2003) J.Immunother. , vol.26 , Issue.4 , pp. 320-331
    • Li, J.1    Hu, P.2    Khawli, L.A.3    Epstein, A.L.4
  • 64
    • 38449106720 scopus 로고    scopus 로고
    • Host mediated antitumoreffect of oncolytic Newcastle disease virus after locoregionalapplication
    • Apostolidis, L.; Schirrmacher, V.; Fournier, P. Host mediated antitumoreffect of oncolytic Newcastle disease virus after locoregionalapplication. Int. J. Oncol., 2007, 31 (5), 1009-1019.
    • (2007) Int. J. Oncol. , vol.31 , Issue.5 , pp. 1009-1019
    • Apostolidis, L.1    Schirrmacher, V.2    Fournier, P.3
  • 65
    • 34249776097 scopus 로고    scopus 로고
    • Local and distant immunemediatedcontrol of colon cancer growth with fusogenic membraneglycoproteins in combination with viral oncolysis
    • Hoffmann, D.; Bayer, W.; Wildner, O. Local and distant immunemediatedcontrol of colon cancer growth with fusogenic membraneglycoproteins in combination with viral oncolysis. Hum. GeneTher., 2007, 18 (5), 435-450.
    • (2007) Hum. GeneTher. , vol.18 , Issue.5 , pp. 435-450
    • Hoffmann, D.1    Bayer, W.2    Wildner, O.3
  • 66
    • 47249098958 scopus 로고    scopus 로고
    • Manipulating both the inhibitory and stimulatory immune systemtowards the success of therapeutic vaccination against chronic viralinfections
    • Ha, S. J.; West, E. E.; Araki, K.; Smith, K. A.; Ahmed, R.Manipulating both the inhibitory and stimulatory immune systemtowards the success of therapeutic vaccination against chronic viralinfections. Immunol. Rev., 2008, 223, 317-333.
    • (2008) Immunol. Rev. , vol.223 , pp. 317-333
    • Ha, S.J.1    West, E.E.2    Araki, K.3    Smith, K.A.4    Ahmed, R.5
  • 68
    • 70349561448 scopus 로고    scopus 로고
    • PD-1/PD-L1 interactionsinhibit antitumor immune responses in a murine acute myeloidleukemia model
    • Zhang, L.; Gajewski, T. F.; Kline, J. PD-1/PD-L1 interactionsinhibit antitumor immune responses in a murine acute myeloidleukemia model. Blood, 2009, 114 (8), 1545-1552.
    • (2009) Blood , vol.114 , Issue.8 , pp. 1545-1552
    • Zhang, L.1    Gajewski, T.F.2    Kline, J.3
  • 69
    • 70449475132 scopus 로고    scopus 로고
    • Blocking PD-1 in cancer immunotherapy
    • Dotti, G. Blocking PD-1 in cancer immunotherapy. Blood, 2009, 114 (8), 1457-1458.
    • (2009) Blood , vol.114 , Issue.8 , pp. 1457-1458
    • Dotti, G.1
  • 70
    • 70349569569 scopus 로고    scopus 로고
    • Tumor antigenspecificCD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
    • Ahmadzadeh, M.; Johnson, L. A.; Heemskerk, B.; Wunderlich, J.R.; Dudley, M. E.; White, D. E.; Rosenberg, S. A. Tumor antigenspecificCD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood, 2009, 114 (8), 1537-1544.
    • (2009) Blood , vol.114 , Issue.8 , pp. 1537-1544
    • Ahmadzadeh, M.1    Johnson, L.A.2    Heemskerk, B.3    Wunderlich, J.R.4    Dudley, M.E.5    White, D.E.6    Rosenberg, S.A.7
  • 71
    • 54449088740 scopus 로고    scopus 로고
    • Selectiveexpansion of a subset of exhausted CD8 T cells by alphaPD-L1blockade
    • Blackburn, S. D.; Shin, H.; Freeman, G. J.; Wherry, E. J. Selectiveexpansion of a subset of exhausted CD8 T cells by alphaPD-L1blockade. Proc. Natl. Acad. Sci. USA, 2008, 105 (39), 15016-15021.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , Issue.39 , pp. 15016-15021
    • Blackburn, S.D.1    Shin, H.2    Freeman, G.J.3    Wherry, E.J.4
  • 72
    • 27644457376 scopus 로고    scopus 로고
    • TGF-beta directly targets cytotoxic Tcell functions during tumor evasion of immune surveillance
    • Thomas, D. A.; Massague, J. TGF-beta directly targets cytotoxic Tcell functions during tumor evasion of immune surveillance.Cancer Cell, 2005, 8 (5), 369-380.
    • (2005) Cancer Cell , vol.8 , Issue.5 , pp. 369-380
    • Thomas, D.A.1    Massague, J.2
  • 74
    • 34547655923 scopus 로고    scopus 로고
    • A unique subset of CD4+CD25highFoxp3+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in thetumor microenvironment
    • Strauss, L.; Bergmann, C.; Szczepanski, M.; Gooding, W.; Johnson, J. T.; Whiteside, T. L. A unique subset of CD4+CD25highFoxp3+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in thetumor microenvironment. Clin. Cancer Res., 2007, 13 (15 Pt 1), 4345-4354.
    • (2007) Clin. Cancer Res. , vol.13 , Issue.15 PART 1 , pp. 4345-4354
    • Strauss, L.1    Bergmann, C.2    Szczepanski, M.3    Gooding, W.4    Johnson, J.T.5    Whiteside, T.L.6
  • 75
    • 0036789939 scopus 로고    scopus 로고
    • A push-pull approach tomaximize vaccine efficacy: Abrogating suppression with an IL-13inhibitor while augmenting help with granulocyte/macrophagecolony-stimulating factor and CD40L
    • Ahlers, J. D.; Belyakov, I. M.; Terabe, M.; Koka, R.; Donaldson, D. D.; Thomas, E. K.; Berzofsky, J. A. A push-pull approach tomaximize vaccine efficacy: abrogating suppression with an IL-13inhibitor while augmenting help with granulocyte/macrophagecolony-stimulating factor and CD40L. Proc. Natl. Acad. Sci. USA, 2002, 99 (20), 13020-13025.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , Issue.20 , pp. 13020-13025
    • Ahlers, J.D.1    Belyakov, I.M.2    Terabe, M.3    Koka, R.4    Donaldson, D.D.5    Thomas, E.K.6    Berzofsky, J.A.7
  • 76
    • 0035734114 scopus 로고    scopus 로고
    • Chemoimmunotherapyand chemo-adoptive immunotherapy of cancer
    • Gomez, G. G.; Hutchison, R. B.; Kruse, C. A. Chemoimmunotherapyand chemo-adoptive immunotherapy of cancer.Cancer Treat. Rev., 2001, 27 (6), 375-402.
    • (2001) Cancer Treat. Rev. , vol.27 , Issue.6 , pp. 375-402
    • Gomez, G.G.1    Hutchison, R.B.2    Kruse, C.A.3
  • 77
    • 33644760378 scopus 로고    scopus 로고
    • Isolation of immunoresistant human glioma cell clones after selection withalloreactive cytotoxic T lymphocytes: Cytogenetic and molecularcytogenetic characterization
    • Gomez, G. G.; Varella-Garcia, M.; Kruse, C. A. Isolation of immunoresistant human glioma cell clones after selection withalloreactive cytotoxic T lymphocytes: cytogenetic and molecularcytogenetic characterization. Cancer Genet Cytogenet., 2006, 165(2), 121-134.
    • (2006) Cancer Genet Cytogenet. , vol.165 , Issue.2 , pp. 121-134
    • Gomez, G.G.1    Varella-Garcia, M.2    Kruse, C.A.3
  • 78
    • 0029060343 scopus 로고
    • Glucocorticoids regulatecalcineurin-dependent trans-activating pathways for interleukin-2gene transcription in human T lymphocytes
    • Paliogianni, F.; Boumpas, D. T. Glucocorticoids regulatecalcineurin-dependent trans-activating pathways for interleukin-2gene transcription in human T lymphocytes. Transplantation, 1995, 59 (9), 1333-1339.
    • (1995) Transplantation , vol.59 , Issue.9 , pp. 1333-1339
    • Paliogianni, F.1    Boumpas, D.T.2
  • 79
    • 0019129232 scopus 로고
    • Mechanism of lymphocyte activation. II. Requirements for macromolecularsynthesis in the production of lymphokines
    • Varesio, L.; Holden, H. T.; Taramelli, D. Mechanism of lymphocyte activation. II. Requirements for macromolecularsynthesis in the production of lymphokines. J. Immunol., 1980, 125(6), 2810-2817.
    • (1980) J. Immunol. , vol.125 , Issue.6 , pp. 2810-2817
    • Varesio, L.1    Holden, H.T.2    Taramelli, D.3
  • 82
    • 34247115020 scopus 로고    scopus 로고
    • Cellular and functionalcharacterization of immunoresistant human glioma cell clonesselected with alloreactive cytotoxic T lymphocytes reveals their upregulatedsynthesis of biologically active TGF-beta
    • Gomez, G. G.; Kruse, C. A. Cellular and functionalcharacterization of immunoresistant human glioma cell clonesselected with alloreactive cytotoxic T lymphocytes reveals their upregulatedsynthesis of biologically active TGF-beta. J.Immunother., 2007, 30 (3), 261-273.
    • (2007) J.Immunother. , vol.30 , Issue.3 , pp. 261-273
    • Gomez, G.G.1    Kruse, C.A.2
  • 83
    • 70449497739 scopus 로고    scopus 로고
    • Regulatory T cells and inhibitorycytokines in autoimmunity
    • Bettini, M.; Vignali, D. A. Regulatory T cells and inhibitorycytokines in autoimmunity. Curr. Opin. Immunol., 2009, 21 (6), 612-618.
    • (2009) Curr. Opin. Immunol. , vol.21 , Issue.6 , pp. 612-618
    • Bettini, M.1    Vignali, D.A.2
  • 84
    • 0020461752 scopus 로고
    • Production of prostaglandin E and an interleukin-1 like factor bycultured astrocytes and C6 glioma cells
    • Fontana, A.; Kristensen, F.; Dubs, R.; Gemsa, D.; Weber, E.Production of prostaglandin E and an interleukin-1 like factor bycultured astrocytes and C6 glioma cells. J. Immunol., 1982, 129 (6), 2413-2419.
    • (1982) J. Immunol. , vol.129 , Issue.6 , pp. 2413-2419
    • Fontana, A.1    Kristensen, F.2    Dubs, R.3    Gemsa, D.4    Weber, E.5
  • 85
    • 0025196599 scopus 로고
    • In vitroprostaglandin E2 production by glioblastoma cells and its effect oninterleukin-2 activation of oncolytic lymphocytes
    • Sawamura, Y.; Diserens, A. C.; de Tribolet, N. In vitroprostaglandin E2 production by glioblastoma cells and its effect oninterleukin-2 activation of oncolytic lymphocytes. J. Neurooncol., 1990, 9 (2), 125-130.
    • (1990) J. Neurooncol. , vol.9 , Issue.2 , pp. 125-130
    • Sawamura, Y.1    Diserens, A.C.2    de Tribolet, N.3
  • 86
    • 0029842830 scopus 로고    scopus 로고
    • Productionof vascular endothelial growth factor by human tumors inhibits thefunctional maturation of dendritic cells
    • Gabrilovich, D. I.; Chen, H. L.; Girgis, K. R.; Cunningham, H. T.; Meny, G. M.; Nadaf, S.; Kavanaugh, D.; Carbone, D. P. Productionof vascular endothelial growth factor by human tumors inhibits thefunctional maturation of dendritic cells. Nat. Med., 1996, 2 (10), 1096-1103.
    • (1996) Nat. Med. , vol.2 , Issue.10 , pp. 1096-1103
    • Gabrilovich, D.I.1    Chen, H.L.2    Girgis, K.R.3    Cunningham, H.T.4    Meny, G.M.5    Nadaf, S.6    Kavanaugh, D.7    Carbone, D.P.8
  • 87
    • 77953378992 scopus 로고    scopus 로고
    • CTLA-4 blockade: Therapeutic potential incancer treatments
    • Tarhini, A. A.; Iqbal, F. CTLA-4 blockade: therapeutic potential incancer treatments. Oncol. Targets Ther., 2010, 3, 15-25.
    • (2010) Oncol. Targets Ther. , vol.3 , pp. 15-25
    • Tarhini, A.A.1    Iqbal, F.2
  • 88
    • 0142137237 scopus 로고    scopus 로고
    • Evidence for atumoral immune resistance mechanism based on tryptophandegradation by indoleamine 2, 3-dioxygenase
    • Uyttenhove, C.; Pilotte, L.; Theate, I.; Stroobant, V.; Colau, D.; Parmentier, N.; Boon, T.; Van den Eynde, B. J. Evidence for atumoral immune resistance mechanism based on tryptophandegradation by indoleamine 2, 3-dioxygenase. Nat. Med., 2003, 9(10), 1269-1274.
    • (2003) Nat. Med. , vol.9 , Issue.10 , pp. 1269-1274
    • Uyttenhove, C.1    Pilotte, L.2    Theate, I.3    Stroobant, V.4    Colau, D.5    Parmentier, N.6    Boon, T.7    Van den Eynde, B.J.8
  • 89
    • 40849140696 scopus 로고    scopus 로고
    • Therapeutic vaccination againstmalignant gliomas based on allorecognition and syngeneic tumorantigens: Proof of principle in two strains of rat
    • Stathopoulos, A.; Samuelson, C.; Milbouw, G.; Hermanne, J. P.; Schijns, V. E.; Chen, T. C. Therapeutic vaccination againstmalignant gliomas based on allorecognition and syngeneic tumorantigens: proof of principle in two strains of rat. Vaccine, 2008, 26(14), 1764-1772.
    • (2008) Vaccine , vol.26 , Issue.14 , pp. 1764-1772
    • Stathopoulos, A.1    Samuelson, C.2    Milbouw, G.3    Hermanne, J.P.4    Schijns, V.E.5    Chen, T.C.6
  • 91
    • 47749142471 scopus 로고    scopus 로고
    • Detection of human cytomegalovirus in differenthistological types of gliomas
    • Scheurer, M. E.; Bondy, M. L.; Aldape, K. D.; Albrecht, T.; El-Zein, R. Detection of human cytomegalovirus in differenthistological types of gliomas. Acta Neuropathol., 2008, 116 (1), 79-86.
    • (2008) Acta Neuropathol. , vol.116 , Issue.1 , pp. 79-86
    • Scheurer, M.E.1    Bondy, M.L.2    Aldape, K.D.3    Albrecht, T.4    El-Zein, R.5
  • 92
    • 39149136486 scopus 로고    scopus 로고
    • Sensitive detection of humancytomegalovirus in tumors and peripheral blood of patientsdiagnosed with glioblastoma
    • Mitchell, D. A.; Xie, W.; Schmittling, R.; Learn, C.; Friedman, A.; McLendon, R. E.; Sampson, J. H. Sensitive detection of humancytomegalovirus in tumors and peripheral blood of patientsdiagnosed with glioblastoma. Neuro Oncol., 2008, 10 (1), 10-18.
    • (2008) Neuro Oncol. , vol.10 , Issue.1 , pp. 10-18
    • Mitchell, D.A.1    Xie, W.2    Schmittling, R.3    Learn, C.4    Friedman, A.5    McLendon, R.E.6    Sampson, J.H.7
  • 93
    • 0024424931 scopus 로고
    • Interleukin-2-activated lymphocytes from brain tumor patients. Acomparison of two preparations generated in vitro
    • Kruse, C. A.; Mitchell, D. H.; Lillehei, K. O.; Johnson, S. D.; McCleary, E. L.; Moore, G. E.; Waldrop, S.; Mierau, G. W.Interleukin-2-activated lymphocytes from brain tumor patients. Acomparison of two preparations generated in vitro. Cancer, 1989, 64 (8), 1629-1637.
    • (1989) Cancer , vol.64 , Issue.8 , pp. 1629-1637
    • Kruse, C.A.1    Mitchell, D.H.2    Lillehei, K.O.3    Johnson, S.D.4    McCleary, E.L.5    Moore, G.E.6    Waldrop, S.7    Mierau, G.W.8
  • 94
    • 70450199686 scopus 로고    scopus 로고
    • The epidermal growth factor variantIII peptide vaccine for treatment of malignant gliomas
    • Li, G.; Mitra, S.; Wong, A. J. The epidermal growth factor variantIII peptide vaccine for treatment of malignant gliomas. Neurosurg.Clin. N Am, 2010, 21 (1), 87-93.
    • (2010) Neurosurg.Clin. N Am , vol.21 , Issue.1 , pp. 87-93
    • Li, G.1    Mitra, S.2    Wong, A.J.3
  • 95
    • 67650688162 scopus 로고    scopus 로고
    • The PEPvIII-KLH (CDX-110)vaccine in glioblastoma multiforme patients
    • Heimberger, A. B.; Sampson, J. H. The PEPvIII-KLH (CDX-110)vaccine in glioblastoma multiforme patients. Expert Opin. Biol.Ther., 2009, 9 (8), 1087-1098.
    • (2009) Expert Opin. Biol.Ther. , vol.9 , Issue.8 , pp. 1087-1098
    • Heimberger, A.B.1    Sampson, J.H.2
  • 96
    • 67649671865 scopus 로고    scopus 로고
    • DCVax-Brain and DC vaccines in thetreatment of GBM
    • Wheeler, C. J.; Black, K. L. DCVax-Brain and DC vaccines in thetreatment of GBM. Expert Opin. Investig. Drugs, 2009, 18 (4), 509-519.
    • (2009) Expert Opin. Investig. Drugs , vol.18 , Issue.4 , pp. 509-519
    • Wheeler, C.J.1    Black, K.L.2
  • 97
    • 10844296758 scopus 로고    scopus 로고
    • Specific recognition and killing of glioblastomamultiforme by interleukin 13-zetakine redirected cytolytic T cells
    • Kahlon, K. S.; Brown, C.; Cooper, L. J.; Raubitschek, A.; Forman, S. J.; Jensen, M. C. Specific recognition and killing of glioblastomamultiforme by interleukin 13-zetakine redirected cytolytic T cells.Cancer Res., 2004, 64 (24), 9160-9166.
    • (2004) Cancer Res. , vol.64 , Issue.24 , pp. 9160-9166
    • Kahlon, K.S.1    Brown, C.2    Cooper, L.J.3    Raubitschek, A.4    Forman, S.J.5    Jensen, M.C.6
  • 98
    • 34250869002 scopus 로고    scopus 로고
    • Rapid generation of CMV pp65-specific T cells for immunotherapy
    • Bao, L.; Sun, Q.; Lucas, K. G. Rapid generation of CMV pp65-specific T cells for immunotherapy. J. Immunother., 2007, 30 (5), 557-561.
    • (2007) J. Immunother. , vol.30 , Issue.5 , pp. 557-561
    • Bao, L.1    Sun, Q.2    Lucas, K.G.3
  • 99
    • 0002995206 scopus 로고    scopus 로고
    • Cytotoxic T Lymphocytes Reactive toPatient Major Histocompatibility Proteins for Therapy of RecurrentPrimary Brain Tumors
    • In, Liau, L.M.; Cloughesy, T. F.; Becker, D. P.; Bigner, D. D., Eds. HumanaPress: Totowa
    • Kruse, C. A.; Rubinstein, D. Cytotoxic T Lymphocytes Reactive toPatient Major Histocompatibility Proteins for Therapy of RecurrentPrimary Brain Tumors. In Brain Tumor Immunotherapy, Liau, L.M.; Cloughesy, T. F.; Becker, D. P.; Bigner, D. D., Eds. HumanaPress: Totowa, 2001; pp. 149-170.
    • (2001) Brain Tumor Immunotherapy , pp. 149-170
    • Kruse, C.A.1    Rubinstein, D.2


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