Conformational plasticity of RNA for target recognition as revealed by the 2.15 Å crystal structure of a human IgG-aptamer complex

Nucleic Acids Research

Volumn 38, Issue 21, 2010, Pages 7822-7829

  Nomura, Yusuke ^a,b   Sugiyama, Shigeru ^b,c   Sakamoto, Taiichi ^a,b   Miyakawa, Shin ^b,d   Adachi, Hiroaki ^b,c,e   Takano, Kazufumi ^b,c,e   Murakami, Satoshi ^b,e,f   Inoue, Tsuyoshi ^b,c,e   Mori, Yusuke ^b,c,e   Nakamura, Yoshikazu ^b,g   Matsumura, Hiroyoshi ^b,c,e  

^a CHIBA INSTITUTE OF TECHNOLOGY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d RIBOMIC Inc   (Japan)

^e 313 Photonics Center Building   (Japan)

^f TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^g UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APTAMER; CALCIUM ION; HYBRID PROTEIN; IMMUNOGLOBULIN G; NUCLEIC ACID; RNA;

ARTICLE; BINDING AFFINITY; CHELATION; CONTROLLED STUDY; CROSS REACTION; CRYSTAL STRUCTURE; HUMAN; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTEIN RNA BINDING; PROTEIN TARGETING; RNA STRUCTURE; STATIC ELECTRICITY; STRUCTURE ANALYSIS;

APTAMERS, NUCLEOTIDE; CATIONS, DIVALENT; CRYSTALLOGRAPHY; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; RNA;

EID: 78649830305     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq615     Document Type: Article

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