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Volumn 38, Issue 6, 2010, Pages 1645-1649

Adapt or die: How eukaryotic cells respond to prolonged activation of the spindle assembly checkpoint

Author keywords

Adaptation; Antimitotic; Mitotic slippage; Spindle assembly checkpoint

Indexed keywords

CELL CYCLE PROTEIN 20; PROTEIN MAD2;

EID: 78649758292     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0381645     Document Type: Conference Paper
Times cited : (14)

References (49)
  • 1
    • 10344241869 scopus 로고    scopus 로고
    • The spindle checkpoint: A quality control mechanism which ensures accurate chromosome segregation
    • Taylor, S.S., Scott, M.I. and Holland, A.J. (2004) The spindle checkpoint: a quality control mechanism which ensures accurate chromosome segregation. Chromosome Res. 12, 599-616
    • (2004) Chromosome Res. , vol.12 , pp. 599-616
    • Taylor, S.S.1    Scott, M.I.2    Holland, A.J.3
  • 2
    • 34247333444 scopus 로고    scopus 로고
    • The spindle-assembly checkpoint in space and time
    • Musacchio, A. and Salmon, E.D. (2007) The spindle-assembly checkpoint in space and time. Nat. Rev. Mol. Cell Biol. 8, 379-393
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 379-393
    • Musacchio, A.1    Salmon, E.D.2
  • 3
    • 41649110636 scopus 로고    scopus 로고
    • Linking kinetochore-microtubule binding to the spindle checkpoint
    • Burke, D.J. and Stukenberg, P.T. (2008) Linking kinetochore-microtubule binding to the spindle checkpoint. Dev. Cell 14, 474-479
    • (2008) Dev. Cell , vol.14 , pp. 474-479
    • Burke, D.J.1    Stukenberg, P.T.2
  • 5
    • 0035945356 scopus 로고    scopus 로고
    • Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation
    • Howell, B.J., McEwen, B.F., Canman, J.C., Hoffman, D.B., Farrar, E.M., Rieder, C.L. and Salmon, E.D. (2005) Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation. J. Cell Biol. 155, 1159-1172
    • (2005) J. Cell Biol. , vol.155 , pp. 1159-1172
    • Howell, B.J.1    McEwen, B.F.2    Canman, J.C.3    Hoffman, D.B.4    Farrar, E.M.5    Rieder, C.L.6    Salmon, E.D.7
  • 6
    • 0035736325 scopus 로고    scopus 로고
    • Kinetochore dynein: Its dynamics and role in the transport of the Rough deal checkpoint protein
    • Wojcik, E., Basto, R., Serr, M., Scaerou, F., Karess, R. and Hays, T. (2001) Kinetochore dynein: its dynamics and role in the transport of the Rough deal checkpoint protein. Nat. Cell Biol. 3, 1001-1007
    • (2001) Nat. Cell Biol. , vol.3 , pp. 1001-1007
    • Wojcik, E.1    Basto, R.2    Serr, M.3    Scaerou, F.4    Karess, R.5    Hays, T.6
  • 7
    • 0037011119 scopus 로고    scopus 로고
    • Identification of a MAD2-binding protein, CMT2, and its role in mitosis
    • Habu, T., Kim, S.H., Weinstein, J. and Matsumoto, T. (2002) Identification of a MAD2-binding protein, CMT2, and its role in mitosis. EMBO J. 21, 6419-6428
    • (2002) EMBO J. , vol.21 , pp. 6419-6428
    • Habu, T.1    Kim, S.H.2    Weinstein, J.3    Matsumoto, T.4
  • 9
    • 4143076016 scopus 로고    scopus 로고
    • Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint
    • Xia, G., Luo, X., Habu, T., Rizo, J., Matsumoto, T. and Yu, H. (2004) Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint. EMBO J. 23, 3133-3143
    • (2004) EMBO J. , vol.23 , pp. 3133-3143
    • Xia, G.1    Luo, X.2    Habu, T.3    Rizo, J.4    Matsumoto, T.5    Yu, H.6
  • 10
    • 36049028674 scopus 로고    scopus 로고
    • p31comet blocks Mad2 activation through structural mimicry
    • Yang, M., Li, B., Tomchick, D.R., Machius, M., Rizo, J., Yu, H. and Luo, X. (2007) p31comet blocks Mad2 activation through structural mimicry. Cell 131, 744-755
    • (2007) Cell , vol.131 , pp. 744-755
    • Yang, M.1    Li, B.2    Tomchick, D.R.3    Machius, M.4    Rizo, J.5    Yu, H.6    Luo, X.7
  • 11
    • 57049097535 scopus 로고    scopus 로고
    • The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction
    • Nilsson, J., Yekezare, M., Minshull, J. and Pines, J. (2008) The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction. Nat. Cell Biol. 10, 1411-1420
    • (2008) Nat. Cell Biol. , vol.10 , pp. 1411-1420
    • Nilsson, J.1    Yekezare, M.2    Minshull, J.3    Pines, J.4
  • 12
    • 34247355517 scopus 로고    scopus 로고
    • Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation
    • Reddy, S.K., Rape, M., Margansky, W.A. and Kirschner, M.W. (2007) Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation. Nature 446, 921-925
    • (2007) Nature , vol.446 , pp. 921-925
    • Reddy, S.K.1    Rape, M.2    Margansky, W.A.3    Kirschner, M.W.4
  • 14
    • 72849116829 scopus 로고    scopus 로고
    • Quantitative proteomic analysis of purified yeast kinetochores identifies a PP1 regulatory subunit
    • Akiyoshi, B., Nelson, C.R., Ranish, J.A. and Biggins, S. (2009) Quantitative proteomic analysis of purified yeast kinetochores identifies a PP1 regulatory subunit. Genes Dev. 23, 2887-2899
    • (2009) Genes Dev. , vol.23 , pp. 2887-2899
    • Akiyoshi, B.1    Nelson, C.R.2    Ranish, J.A.3    Biggins, S.4
  • 15
    • 67650960616 scopus 로고    scopus 로고
    • Protein phosphatase 1 regulates exit from the spindle checkpoint in budding yeast
    • Pinsky, B.A., Nelson, C.R. and Biggins, S. (2009) Protein phosphatase 1 regulates exit from the spindle checkpoint in budding yeast. Curr. Biol. 19, 1182-1187
    • (2009) Curr. Biol. , vol.19 , pp. 1182-1187
    • Pinsky, B.A.1    Nelson, C.R.2    Biggins, S.3
  • 16
    • 67650998480 scopus 로고    scopus 로고
    • A novel protein phosphatase 1-dependent spindle checkpoint silencing mechanism
    • Vanoosthuyse, V. and Hardwick, K.G. (2009) A novel protein phosphatase 1-dependent spindle checkpoint silencing mechanism. Curr. Biol. 19, 1176-1181
    • (2009) Curr. Biol. , vol.19 , pp. 1176-1181
    • Vanoosthuyse, V.1    Hardwick, K.G.2
  • 18
    • 7744233719 scopus 로고    scopus 로고
    • Stuck in division or passing through: What happens when cells cannot satisfy the spindle assembly checkpoint
    • Rieder, C.L. and Maiato, H. (2004) Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint. Dev. Cell 7, 637-651
    • (2004) Dev. Cell , vol.7 , pp. 637-651
    • Rieder, C.L.1    Maiato, H.2
  • 19
    • 22244478043 scopus 로고    scopus 로고
    • Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death
    • Weaver, B.A. and Cleveland, D.W. (2005) Decoding the links between mitosis, cancer, and chemotherapy: the mitotic checkpoint, adaptation, and cell death. Cancer Cell 8, 7-12
    • (2005) Cancer Cell , vol.8 , pp. 7-12
    • Weaver, B.A.1    Cleveland, D.W.2
  • 20
    • 48449098623 scopus 로고    scopus 로고
    • Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs
    • Gascoigne, K.E. and Taylor, S.S. (2008) Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. Cancer Cell 14, 111-122
    • (2008) Cancer Cell , vol.14 , pp. 111-122
    • Gascoigne, K.E.1    Taylor, S.S.2
  • 21
    • 56249107716 scopus 로고    scopus 로고
    • Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate
    • Orth, J.D., Tang, Y., Shi, J., Loy, C.T., Amendt, C., Wilm, C., Zenke, F.T. and Mitchison, T.J. (2008) Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate. Mol. Cancer Ther. 7, 3480-3489
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 3480-3489
    • Orth, J.D.1    Tang, Y.2    Shi, J.3    Loy, C.T.4    Amendt, C.5    Wilm, C.6    Zenke, F.T.7    Mitchison, T.J.8
  • 22
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • Jordan, M.A. and Wilson, L. (2004) Microtubules as a target for anticancer drugs. Nat. Rev. Cancer 4, 253-265
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 23
    • 0030910037 scopus 로고    scopus 로고
    • p53 and ATM: Cell cycle, cell death, and cancer
    • Morgan, S.E. and Kastan, M.B. (1997) p53 and ATM: cell cycle, cell death, and cancer. Adv. Cancer Res. 71, 1-25
    • (1997) Adv. Cancer Res. , vol.71 , pp. 1-25
    • Morgan, S.E.1    Kastan, M.B.2
  • 28
    • 33845628037 scopus 로고    scopus 로고
    • Budding yeast DNA damage adaptation mutants exhibit defects in mitotic exit
    • Jin, F. and Wang, Y. (2006) Budding yeast DNA damage adaptation mutants exhibit defects in mitotic exit. Cell Cycle 5, 2914-2919
    • (2006) Cell Cycle , vol.5 , pp. 2914-2919
    • Jin, F.1    Wang, Y.2
  • 29
    • 0030885666 scopus 로고    scopus 로고
    • CDC5 and CKII control adaptation to the yeast DNA damage checkpoint
    • Toczyski, D.P., Galgoczy, D.J. and Hartwell, L.H. (1997) CDC5 and CKII control adaptation to the yeast DNA damage checkpoint. Cell 90, 1097-1106
    • (1997) Cell , vol.90 , pp. 1097-1106
    • Toczyski, D.P.1    Galgoczy, D.J.2    Hartwell, L.H.3
  • 30
    • 33744996707 scopus 로고    scopus 로고
    • Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint
    • Brito, D.A. and Rieder, C.L. (2006) Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint. Curr. Biol. 16, 1194-1200
    • (2006) Curr. Biol. , vol.16 , pp. 1194-1200
    • Brito, D.A.1    Rieder, C.L.2
  • 31
    • 0042831247 scopus 로고    scopus 로고
    • Mutations in the yeast cyclin-dependent kinase Cdc28 reveal a role in the spindle assembly checkpoint
    • Kitazono, A.A., Garza, D.A. and Kron, S.J. (2003) Mutations in the yeast cyclin-dependent kinase Cdc28 reveal a role in the spindle assembly checkpoint. Mol. Genet. Genomics 269, 672-684
    • (2003) Mol. Genet. Genomics , vol.269 , pp. 672-684
    • Kitazono, A.A.1    Garza, D.A.2    Kron, S.J.3
  • 32
    • 0030987085 scopus 로고    scopus 로고
    • Inactivation of the cyclin-dependent kinase Cdc28 abrogates cell cycle arrest induced by DNA damage and disassembly of mitotic spindles in Saccharomyces cerevisiae
    • Li, X. and Cai, M. (1997) Inactivation of the cyclin-dependent kinase Cdc28 abrogates cell cycle arrest induced by DNA damage and disassembly of mitotic spindles in Saccharomyces cerevisiae. Mol. Cell. Biol. 17, 2723-2734
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2723-2734
    • Li, X.1    Cai, M.2
  • 33
    • 0037416186 scopus 로고    scopus 로고
    • Function of Cdc2p-dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint
    • Yamaguchi, S., Decottignies, A. and Nurse, P. (2003) Function of Cdc2p-dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint. EMBO J. 22, 1075-1087
    • (2003) EMBO J. , vol.22 , pp. 1075-1087
    • Yamaguchi, S.1    Decottignies, A.2    Nurse, P.3
  • 35
    • 77953594908 scopus 로고    scopus 로고
    • Substrate degradation by the anaphase promoting complex occurs during mitotic slippage
    • Lee, J., Kim, J.A., Margolis, R.L. and Fotedar, R. (2010) Substrate degradation by the anaphase promoting complex occurs during mitotic slippage. Cell Cycle 9
    • (2010) Cell Cycle , vol.9
    • Lee, J.1    Kim, J.A.2    Margolis, R.L.3    Fotedar, R.4
  • 36
    • 22244459880 scopus 로고    scopus 로고
    • Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage
    • Tao, W., South, V.J., Zhang, Y., Davide, J.P., Farrell, L., Kohl, N.E., Sepp-Lorenzino, L. and Lobell, R.B. (2005) Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage. Cancer Cell 8, 49-59
    • (2005) Cancer Cell , vol.8 , pp. 49-59
    • Tao, W.1    South, V.J.2    Zhang, Y.3    Davide, J.P.4    Farrell, L.5    Kohl, N.E.6    Sepp-Lorenzino, L.7    Lobell, R.B.8
  • 37
    • 78649666050 scopus 로고    scopus 로고
    • The RSC chromatin-remodelling complex influences mitotic exit and adaptation to the spindle assembly checkpoint by controlling the CDC14 phosphatase
    • in the press
    • Rossio, V., Galati, E., Ferrari, M., Pellicioli, A., Sutani, T., Shirahige, K., Lucchini, G. and Piatti, S. (2010) The RSC chromatin-remodelling complex influences mitotic exit and adaptation to the spindle assembly checkpoint by controlling the CDC14 phosphatase. J. Cell Biol., in the press
    • (2010) J. Cell Biol.
    • Rossio, V.1    Galati, E.2    Ferrari, M.3    Pellicioli, A.4    Sutani, T.5    Shirahige, K.6    Lucchini, G.7    Piatti, S.8
  • 38
    • 0030464317 scopus 로고    scopus 로고
    • Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast
    • Minshull, J., Straight, A., Rudner, A.D., Dernburg, A.F., Belmont, A. and Murray, A.W. (1996) Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast. Curr. Biol. 6, 1609-1620
    • (1996) Curr. Biol. , vol.6 , pp. 1609-1620
    • Minshull, J.1    Straight, A.2    Rudner, A.D.3    Dernburg, A.F.4    Belmont, A.5    Murray, A.W.6
  • 39
    • 0032254350 scopus 로고    scopus 로고
    • The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk- dependent phosphorylation
    • Visintin, R., Craig, K., Hwang, E.S., Prinz, S., Tyers, M. and Amon, A. (1998) The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk- dependent phosphorylation. Mol. Cell 2, 709-718
    • (1998) Mol. Cell , vol.2 , pp. 709-718
    • Visintin, R.1    Craig, K.2    Hwang, E.S.3    Prinz, S.4    Tyers, M.5    Amon, A.6
  • 40
    • 0033574594 scopus 로고    scopus 로고
    • Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex
    • Shou, W., Seol, J.H., Shevchenko, A., Baskerville, C., Moazed, D., Chen, Z.W., Jang, J., Charbonneau, H. and Deshaies, R.J. (1999) Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex. Cell 97, 233-244
    • (1999) Cell , vol.97 , pp. 233-244
    • Shou, W.1    Seol, J.H.2    Shevchenko, A.3    Baskerville, C.4    Moazed, D.5    Chen, Z.W.6    Jang, J.7    Charbonneau, H.8    Deshaies, R.J.9
  • 41
    • 0033614303 scopus 로고    scopus 로고
    • Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus
    • Visintin, R., Hwang, E.S. and Amon, A. (1999) Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus. Nature 398, 818-823
    • (1999) Nature , vol.398 , pp. 818-823
    • Visintin, R.1    Hwang, E.S.2    Amon, A.3
  • 42
    • 10944240060 scopus 로고    scopus 로고
    • Closing mitosis: The functions of the Cdc14 phosphatase and its regulation
    • Stegmeier, F and Amon, A (2004) Closing mitosis: the functions of the Cdc14 phosphatase and its regulation. Annu. Rev. Genet. 38, 203-232
    • (2004) Annu. Rev. Genet. , vol.38 , pp. 203-232
    • Stegmeier, F.1    Amon, A.2
  • 43
    • 0037169353 scopus 로고    scopus 로고
    • Separase, Polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization during early anaphase
    • Stegmeier, F., Visintin, R. and Amon, A. (2002) Separase, Polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization during early anaphase. Cell 108, 207-220
    • (2002) Cell , vol.108 , pp. 207-220
    • Stegmeier, F.1    Visintin, R.2    Amon, A.3
  • 44
    • 23044479628 scopus 로고    scopus 로고
    • Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair
    • Chai, B., Huang, J., Cairns, B.R. and Laurent, B.C. (2005) Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair. Genes Dev. 19, 1656-1661
    • (2005) Genes Dev. , vol.19 , pp. 1656-1661
    • Chai, B.1    Huang, J.2    Cairns, B.R.3    Laurent, B.C.4
  • 45
    • 34948874900 scopus 로고    scopus 로고
    • Dual chromatin remodeling roles for RSC during DNA double strand break induction and repair at the yeast MAT locus
    • Kent, N.A., Chambers, A.L. and Downs, J.A. (2007) Dual chromatin remodeling roles for RSC during DNA double strand break induction and repair at the yeast MAT locus. J. Biol. Chem. 282, 27693-27701
    • (2007) J. Biol. Chem. , vol.282 , pp. 27693-27701
    • Kent, N.A.1    Chambers, A.L.2    Downs, J.A.3
  • 46
    • 34547907083 scopus 로고    scopus 로고
    • RSC functions as an early double-strand-break sensor in the cell's response to DNA damage
    • Liang, B., Qiu, J., Ratnakumar, K. and Laurent, B.C. (2007) RSC functions as an early double-strand-break sensor in the cell's response to DNA damage. Curr. Biol. 17, 1432-1437
    • (2007) Curr. Biol. , vol.17 , pp. 1432-1437
    • Liang, B.1    Qiu, J.2    Ratnakumar, K.3    Laurent, B.C.4
  • 47
    • 33847176208 scopus 로고    scopus 로고
    • RSC mobilizes nucleosomes to improve accessibility of repair machinery to the damaged chromatin
    • Shim, E.Y., Hong, S.J., Oum, J.H., Yanez, Y., Zhang, Y. and Lee, S.E. (2007) RSC mobilizes nucleosomes to improve accessibility of repair machinery to the damaged chromatin. Mol. Cell. Biol. 27, 1602-1613
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 1602-1613
    • Shim, E.Y.1    Hong, S.J.2    Oum, J.H.3    Yanez, Y.4    Zhang, Y.5    Lee, S.E.6
  • 48
    • 18144423533 scopus 로고    scopus 로고
    • The yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaks
    • Shim, E.Y., Ma, J.L., Oum, J.H., Yanez, Y. and Lee, S.E. (2005) The yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaks. Mol. Cell. Biol. 25, 3934-3944
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 3934-3944
    • Shim, E.Y.1    Ma, J.L.2    Oum, J.H.3    Yanez, Y.4    Lee, S.E.5
  • 49
    • 70349452101 scopus 로고    scopus 로고
    • Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly
    • Huang, H.C., Shi, J., Orth, J.D. and Mitchison, T.J. (2009) Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. Cancer Cell 16, 347-358
    • (2009) Cancer Cell , vol.16 , pp. 347-358
    • Huang, H.C.1    Shi, J.2    Orth, J.D.3    Mitchison, T.J.4


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