Distinct role of spleen tyrosine kinase in the early phosphorylation of inhibitor of κBα via activation of the phosphoinositide-3-kinase and Akt pathways

International Journal of Biochemistry and Cell Biology

Volumn 41, Issue 4, 2009, Pages 811-821

  Lee, Yong Gyu ^a   Chain, Benjamin M ^b   Cho, Jae Youl ^a  

^a Kangwon National University   (South Korea)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

I B ; LPS induced inflammatory response; Macrophages; Non receptor type protein tyrosine kinases; Syk

Indexed keywords

I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE SYK; PROTEIN TYROSINE KINASE;

ANIMAL EXPERIMENT; ARTICLE; C57BL 6 MOUSE; CELL CULTURE; DNA TRANSFECTION; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME INHIBITION; ENZYME REGULATION; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOMODULATION; IMMUNOPRECIPITATION; INFLAMMATION; INSTITUTE FOR CANCER RESEARCH MOUSE; MACROPHAGE; MALE; METABOLIC REGULATION; MOUSE; NONHUMAN; PHOSPHORYLATION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; I-KAPPA B PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; NF-KAPPA B; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STILBENES; TRANSFECTION;

EID: 59649090426     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2008.08.011     Document Type: Article

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